Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation

British Journal of Pharmacology

Volumn 141, Issue 6, 2004, Pages 979-987

  Dugo, Laura ^a   Marzocco, Stefania ^b   Mazzon, Emanuela ^c   Di Paola, Rosanna ^a   Genovese, Tiziana ^a   Caputi, Achille P ^a   Cuzzocrea, Salvatore ^a,c  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Adhesion molecules; Inflammation; iNOS; Peroxynitrite; Pleurisy; Rat; Reactive oxygen species

Indexed keywords

2 AMINO(1 IMINOETHYLAMINO) 5 THIOHEPTANOIC ACID; 3 NITROTYROSINE; ANTIINFLAMMATORY AGENT; CARRAGEENAN; HEPTANOIC ACID DERIVATIVE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); S [2 (1 IMINOETHYLAMINO)ETHYL]HOMOCYSTEINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DOSE RESPONSE; FLUID RETENTION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIPID PEROXIDATION; MALE; NONHUMAN; PLEURA CAVITY; PNEUMONIA; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STAINING; UPREGULATION;

ANIMALS; CARRAGEENAN; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1; INTERLEUKIN-1BETA; LUNG; MALE; MALONDIALDEHYDE; NITRATES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PEPTIDE FRAGMENTS; PEROXIDASE; PLEUROPNEUMONIA; PNEUMONIA; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; SULFIDES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 1942472504     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705683     Document Type: Article

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