New insights in protein kinase conformational dynamics

Current Topics in Medicinal Chemistry

Volumn 12, Issue 17, 2012, Pages 1889-1895

  Saladino, Giorgio ^a   Gervasio, Francesco Luigi ^a  

^a Structural Biology and Biocomputing Programme   (Spain)

Author keywords

Allostery; Imatinib; Kinase; Metadynamics; Molecular dynamics; Signaling

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 5; DASATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; IMATINIB; PROTEIN KINASE;

ALLOSTERISM; ALPHA HELIX; ARTICLE; BINDING SITE; COMPUTER SIMULATION; HUMAN; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DATA BANK; PROTEIN DEPHOSPHORYLATION; SRC HOMOLOGY DOMAIN; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; COMPUTATIONAL BIOLOGY; DRUG DISCOVERY; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SOFTWARE;

EID: 84872241513     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612804547407     Document Type: Article

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