Comprehensive structural and functional characterization of the human kinome by protein structure modeling and ligand virtual screening

Journal of Chemical Information and Modeling

Volumn 50, Issue 10, 2010, Pages 1839-1854

  Brylinski, Michal ^a   Skolnick, Jeffrey ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; DIGITAL LIBRARIES; ENZYME INHIBITION; USER INTERFACES;

ACADEMIC COMMUNITY; BIOACTIVE COMPOUNDS; FUNCTIONAL CHARACTERIZATION; HIERARCHICAL APPROACH; STRUCTURAL CHARACTERIZATION; STRUCTURAL GENOMICS; THREE-DIMENSIONAL STRUCTURE; VIRTUAL LIGAND SCREENING;

LIGANDS;

LIGAND; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; HUMAN; METABOLISM; METHODOLOGY; PROTEIN CONFORMATION; PROTEOMICS;

BINDING SITES; DRUG DESIGN; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEOMICS;

EID: 77958567426     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci100235n     Document Type: Article

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