Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent Mechanism

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Nguyen, Jacqueline ^a   Tang, Simon Y ^b   Nguyen, Daniel ^b   Alliston, Tamara ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SCLEROSTIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BIOSYNTHESIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MECHANICAL LOAD; MOUSE; NONHUMAN; OSSIFICATION; OSTEOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SENSITIVITY ANALYSIS;

ANIMALS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GENES, REPORTER; GLYCOPROTEINS; LUCIFERASES; MALE; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOCLASTS; OSTEOCYTES; OSTEOGENESIS; PHOSPHORYLATION; SMAD2 PROTEIN; SMAD3 PROTEIN; TIBIA; TRANSFORMING GROWTH FACTOR BETA; WEIGHT-BEARING; X-RAY MICROTOMOGRAPHY;

EID: 84872157358     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053813     Document Type: Article

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