Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension

Stem Cells and Development

Volumn 21, Issue 7, 2012, Pages 1176-1186

  Wang, Yang Kao ^a,b   Yu, Xiang ^a   Cohen, Daniel M ^a   Wozniak, Michele A ^a   Yang, Michael T ^a   Gao, Lin ^a   Eyckmans, Jeroen ^a   Chen, Christopher S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; COMPLEMENTARY DNA; CYTOKINE; DEXAMETHASONE; DNA; PROTEIN KINASE; RHO ASSOCIATED PROTEIN KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RNA; SMAD1 PROTEIN; SMAD4 PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BONE DEVELOPMENT; CELL SHAPE; CELL SPREADING; CONTROLLED STUDY; CYTOSKELETON; DIMERIZATION; ENZYME ASSAY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; BONE MORPHOGENETIC PROTEIN 2; CELL ADHESION; CELL DIFFERENTIATION; CELL SHAPE; CELLS, CULTURED; CYTOSKELETON; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMANS; MESENCHYMAL STEM CELLS; MYOSINS; OSTEOGENESIS; PHOSPHORYLATION; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SMAD PROTEINS; STRESS FIBERS; STRESS, MECHANICAL;

EID: 84860140464     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0293     Document Type: Article

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