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Volumn 145, Issue 2, 2013, Pages 626-637

Molecular mechanism of capillarisin-mediated inhibition of MyD88/TIRAP inflammatory signaling in in vitro and in vivo experimental models

Author keywords

Anti inflammatory; Capillarisin; CFA; MAPKs AP 1; MyD88 TIRAP; NF B

Indexed keywords

ANTIINFLAMMATORY AGENT; CAPILLARISIN; CARRAGEENAN; CYCLOOXYGENASE 2; DEXAMETHASONE; DNA BINDING PROTEIN; FREUND ADJUVANT; GRIESS REAGENT; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; NITRITE; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEIN P50; REAGENT; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TIRAP PROTEIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84872146374     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.12.001     Document Type: Article
Times cited : (67)

References (41)
  • 2
    • 0035217962 scopus 로고    scopus 로고
    • Mode of action of Freund's adjuvants in experimetal modes of autoimmunes diseases
    • A. Billiau, and P. Matthys Mode of action of Freund's adjuvants in experimetal modes of autoimmunes diseases Journal of Leukocyte Biology 70 2001 849 860
    • (2001) Journal of Leukocyte Biology , vol.70 , pp. 849-860
    • Billiau, A.1    Matthys, P.2
  • 3
    • 0035979737 scopus 로고    scopus 로고
    • Duration of nuclear NF-κB action regulated by reversible acetylation
    • L. Chen, W. Fischle, E. Verdin, and W.C. Greene Duration of nuclear NF-κB action regulated by reversible acetylation Science 293 2001 1653 1657
    • (2001) Science , vol.293 , pp. 1653-1657
    • Chen, L.1    Fischle, W.2    Verdin, E.3    Greene, W.C.4
  • 5
    • 37349053781 scopus 로고    scopus 로고
    • Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis draconis, a dragon's blood resin, in RAW 264.7 cells
    • C.S. Choy, C.M. Hu, W.T. Chiu, C.S. Lam, Y. Ting, S.H. Tsai, and T.C. Wang Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis draconis, a dragon's blood resin, in RAW 264.7 cells Journal of Ethnopharmacology 115 2008 455 462
    • (2008) Journal of Ethnopharmacology , vol.115 , pp. 455-462
    • Choy, C.S.1    Hu, C.M.2    Chiu, W.T.3    Lam, C.S.4    Ting, Y.5    Tsai, S.H.6    Wang, T.C.7
  • 7
    • 84855967600 scopus 로고    scopus 로고
    • Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models
    • K.A. da Silva, M.N. Manjavachi, A.F. Paszcuk, M. Pivatto, C. Viegas Jr, V.S. Bolzani, and J.B. Calixto Plant derived alkaloid (-)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models Neuropharmacology 62 2012 967 977
    • (2012) Neuropharmacology , vol.62 , pp. 967-977
    • Da Silva, K.A.1    Manjavachi, M.N.2    Paszcuk, A.F.3    Pivatto, M.4    Viegas, Jr.C.5    Bolzani, V.S.6    Calixto, J.B.7
  • 14
    • 70149121274 scopus 로고    scopus 로고
    • Artemisia capillaris inhibits lipid accumulation in 3T3-L1 adipocytes and obesity in C57BL/6J mice fed a high fat diet
    • J.H. Hong, E.Y. Hwang, H.J. Kim, Y.J. Jeong, and I.S. Lee Artemisia capillaris inhibits lipid accumulation in 3T3-L1 adipocytes and obesity in C57BL/6J mice fed a high fat diet Journal of Medicinal Food 12 2009 736 745
    • (2009) Journal of Medicinal Food , vol.12 , pp. 736-745
    • Hong, J.H.1    Hwang, E.Y.2    Kim, H.J.3    Jeong, Y.J.4    Lee, I.S.5
  • 15
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • T. Horng, G.M. Barton, and R. Medzhitov TIRAP: an adapter molecule in the Toll signaling pathway Nature Immunology 2 2001 835 841
    • (2001) Nature Immunology , vol.2 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 17
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • T. Kawai, O. Takeuchi, T. Fujita, J. Inoue, P.F. Muhlradt, S. Sato, K. Hoshino, and S. Akira Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes Journal of Immunology 167 2001 5887 5894
    • (2001) Journal of Immunology , vol.167 , pp. 5887-5894
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6    Hoshino, K.7    Akira, S.8
  • 18
    • 84863015641 scopus 로고    scopus 로고
    • Anti-inflammatory mechanism of 15,16-epoxy-3α-hydroxylabda-8,13(16) ,14-trien-7-one via inhibition of LPS-induced multicellular signaling pathways
    • S. Khan, O. Shehzad, H.G. Jin, E.R. Woo, S.S. Kang, S.W. Baek, J. Kim, and Y.S. Kim Anti-inflammatory mechanism of 15,16-epoxy-3α-hydroxylabda-8, 13(16),14-trien-7-one via inhibition of LPS-induced multicellular signaling pathways Journal of Natural Products 75 2012 67 71
    • (2012) Journal of Natural Products , vol.75 , pp. 67-71
    • Khan, S.1    Shehzad, O.2    Jin, H.G.3    Woo, E.R.4    Kang, S.S.5    Baek, S.W.6    Kim, J.7    Kim, Y.S.8
  • 22
    • 2442549715 scopus 로고    scopus 로고
    • Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-α in microglia
    • H.S. Kim, S.Y. Whang, M.S. Woo, J.S. Park, W.K. Kim, and I.O. Han Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-α in microglia Journal of Neuroimmunology 151 2004 85 93
    • (2004) Journal of Neuroimmunology , vol.151 , pp. 85-93
    • Kim, H.S.1    Whang, S.Y.2    Woo, M.S.3    Park, J.S.4    Kim, W.K.5    Han, I.O.6
  • 23
    • 2942609150 scopus 로고    scopus 로고
    • Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-κB and c-Jun NH2-terminal kinase
    • Y.H. Kim, S.H. Lee, J.Y. Lee, S.W. Choi, J.W. Park, and T.K. Kwon Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-κB and c-Jun NH2-terminal kinase European Journal of Pharmacology 494 2004 1 9
    • (2004) European Journal of Pharmacology , vol.494 , pp. 1-9
    • Kim, Y.H.1    Lee, S.H.2    Lee, J.Y.3    Choi, S.W.4    Park, J.W.5    Kwon, T.K.6
  • 24
    • 27844479656 scopus 로고    scopus 로고
    • Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals
    • J.K. Kundu, and Y.J. Surh Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals Mutation Research 591 2005 123 146
    • (2005) Mutation Research , vol.591 , pp. 123-146
    • Kundu, J.K.1    Surh, Y.J.2
  • 25
    • 80755125291 scopus 로고    scopus 로고
    • Inhibition of 5-lipoxygenase and skin inflammation by the aerial parts of Artemisia capillaris and its constituents
    • O.S. Kwon, J.S. Choi, M.N. Islam, Y.S. Kim, and H.P. Kim Inhibition of 5-lipoxygenase and skin inflammation by the aerial parts of Artemisia capillaris and its constituents Archives of Pharmacal Research 34 2011 1561 1569
    • (2011) Archives of Pharmacal Research , vol.34 , pp. 1561-1569
    • Kwon, O.S.1    Choi, J.S.2    Islam, M.N.3    Kim, Y.S.4    Kim, H.P.5
  • 26
    • 72449121371 scopus 로고    scopus 로고
    • Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-κB, STAT3 and C/EBP signaling pathways
    • C.S. Lai, J.H. Lee, C.T. Ho, C.B. Liu, J.M. Wang, Y.J. Wang, and M.H. Pan Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-κB, STAT3 and C/EBP signaling pathways Journal of Agricultural and Food Chemistry 57 2009 10990 10998
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , pp. 10990-10998
    • Lai, C.S.1    Lee, J.H.2    Ho, C.T.3    Liu, C.B.4    Wang, J.M.5    Wang, Y.J.6    Pan, M.H.7
  • 27
    • 37549026851 scopus 로고    scopus 로고
    • Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-κB-dependent MMP-9 expression
    • S.O. Lee, Y.J. Jeong, M. Kim, C.H. Kim, and I.S. Lee Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-κB-dependent MMP-9 expression Biochemical Biophysical Research Communications 366 2008 1019 1024
    • (2008) Biochemical Biophysical Research Communications , vol.366 , pp. 1019-1024
    • Lee, S.O.1    Jeong, Y.J.2    Kim, M.3    Kim, C.H.4    Lee, I.S.5
  • 28
    • 48049093247 scopus 로고    scopus 로고
    • Differential IL-6 and VEGF secretion in adult and neonatal mesenchymal stem cells: Role of NF-κB
    • N.M. Novotny, T.A. Markel, P.R. Crisostomo, and D.R. Meldrum Differential IL-6 and VEGF secretion in adult and neonatal mesenchymal stem cells: role of NF-κB Cytokine 43 2008 215 219
    • (2008) Cytokine , vol.43 , pp. 215-219
    • Novotny, N.M.1    Markel, T.A.2    Crisostomo, P.R.3    Meldrum, D.R.4
  • 29
    • 77949489152 scopus 로고    scopus 로고
    • Anti-inflammatory effect of lucidone in mice via inhibition of NF-κB/MAP kinase pathway
    • K.J. Senthil Kumar, H.W. Hsieh, and S.Y. Wang Anti-inflammatory effect of lucidone in mice via inhibition of NF-κB/MAP kinase pathway International Immunopharmacolology 10 2010 385 392
    • (2010) International Immunopharmacolology , vol.10 , pp. 385-392
    • Senthil Kumar, K.J.1    Hsieh, H.W.2    Wang, S.Y.3
  • 30
    • 70249084239 scopus 로고    scopus 로고
    • Lucidone inhibits iNOS and COX-2 expression in LPS-induced RAW 264.7 murine macrophage cells via NF-κB and MAPKs signaling pathways
    • K.J. Senthil Kumar, and S.Y. Wang Lucidone inhibits iNOS and COX-2 expression in LPS-induced RAW 264.7 murine macrophage cells via NF-κB and MAPKs signaling pathways Planta Medica 75 2009 494 500
    • (2009) Planta Medica , vol.75 , pp. 494-500
    • Senthil Kumar, K.J.1    Wang, S.Y.2
  • 31
    • 73449090078 scopus 로고    scopus 로고
    • Anti-inflammatory activity of hispidol A 25-methyl ether, a triterpenoid isolated from Ponciri Immaturus Fructus
    • E.M. Shin, H.Y. Zhou, G.H. Xu, S.H. Lee, I. Merfort, and Y.S. Kim Anti-inflammatory activity of hispidol A 25-methyl ether, a triterpenoid isolated from Ponciri Immaturus Fructus European Journal of Pharmacology 627 2010 318 324
    • (2010) European Journal of Pharmacology , vol.627 , pp. 318-324
    • Shin, E.M.1    Zhou, H.Y.2    Xu, G.H.3    Lee, S.H.4    Merfort, I.5    Kim, Y.S.6
  • 32
    • 0037039665 scopus 로고    scopus 로고
    • Distinct roles of the IκB kinase alpha and beta subunits in liberating nuclear factor κb (NF-κB) from IκB and in phosphorylating the p65 subunit of NF-κB
    • N. Sizemore, N. Lerner, N. Dombrowski, H. Sakurai, and G.R. Stark Distinct roles of the IκB kinase alpha and beta subunits in liberating nuclear factor κB (NF-κB) from IκB and in phosphorylating the p65 subunit of NF-κB Journal of Chemical Biology 277 2002 3863 3869
    • (2002) Journal of Chemical Biology , vol.277 , pp. 3863-3869
    • Sizemore, N.1    Lerner, N.2    Dombrowski, N.3    Sakurai, H.4    Stark, G.R.5
  • 33
    • 34748855636 scopus 로고    scopus 로고
    • NFκB and NFκBI polymorphisms in relation to susceptibility of tumour and other diseases
    • X.F. Sun, and H. Zhang NFκB and NFκBI polymorphisms in relation to susceptibility of tumour and other diseases Histology and Histopathology 22 2007 1387 1398
    • (2007) Histology and Histopathology , vol.22 , pp. 1387-1398
    • Sun, X.F.1    Zhang, H.2
  • 34
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-κB activation
    • Y.J. Surh, K.S. Chun, H.H. Cha, S.S. Han, Y.S. Keum, K.K. Park, and S.S. Lee Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation Mutation Research 480-481 2001 243 268
    • (2001) Mutation Research , vol.480-481 , pp. 243-268
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3    Han, S.S.4    Keum, Y.S.5    Park, K.K.6    Lee, S.S.7
  • 39
    • 46749111110 scopus 로고    scopus 로고
    • An investigation of the anti-inflammatory and analgesic effects of Orthosiphon stamineus leaf extract
    • M.F. Yam, M.Z. Asmawi, and R. Basir An investigation of the anti-inflammatory and analgesic effects of Orthosiphon stamineus leaf extract Journal of Medicinal Food 11 2008 362 368
    • (2008) Journal of Medicinal Food , vol.11 , pp. 362-368
    • Yam, M.F.1    Asmawi, M.Z.2    Basir, R.3
  • 41
    • 0034450123 scopus 로고    scopus 로고
    • Molecular mechanisms of NF-κB activation induced by bacterial lipopolysaccharide through Toll-like receptors
    • G. Zhang, and S. Ghosh Molecular mechanisms of NF-κB activation induced by bacterial lipopolysaccharide through Toll-like receptors Journal of Endotoxin Research 6 2000 453 457
    • (2000) Journal of Endotoxin Research , vol.6 , pp. 453-457
    • Zhang, G.1    Ghosh, S.2


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