Interplay between Th1 and Th17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Gαi2-deficient mouse

International Immunology

Volumn 25, Issue 1, 2013, Pages 35-44

  Götlind, Yu Yuan ^a   Fritsch Fredin, Maria ^b   Kumawat, Ashok Kumar ^c   Strid, Hilja ^c   Willén, Roger ^d   Rangel, Ignacio ^c   Bland, Paul W ^a   Hörnquist, Elisabeth Hultgren ^c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c ÖREBRO UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Chemokines; Constrained correspondence analysis; Dysplasia; Inflammatory bowel disease; Real time RT PCR

Indexed keywords

CXCL1 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON CANCER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; EFFECTOR CELL; FEMALE; HISTOLOGY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; SPLEEN WEIGHT; TH1 CELL; TH17 CELL; THYMUS; WILD TYPE;

ANIMALS; COLITIS; COLON; COLONIC NEOPLASMS; CYTOKINES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; INTESTINE, SMALL; MALE; MICE; MICE, KNOCKOUT; ORGAN SIZE; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SPLEEN; TH1 CELLS; TH1-TH2 BALANCE; TH17 CELLS; THYMUS GLAND; TRANSCRIPTION, GENETIC;

EID: 84872130510     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxs089     Document Type: Article

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