Modulation of Th1/Th2 balance by infliximab rescues postoperative occurrence of small-intestinal inflammation associated with ulcerative colitis

Digestive Diseases and Sciences

Volumn 55, Issue 6, 2010, Pages 1781-1784

  Akitake, Reiko ^a   Nakase, Hiroshi ^a   Tamaoki, Masashi ^a   Ueno, Satoru ^a   Mikami, Sakae ^a   Chiba, Tsutomu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Infliximab; Small intestinal inflammation; Th1 Th2 balance; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; C REACTIVE PROTEIN; CORTICOSTEROID; GAMMA INTERFERON; INFLIXIMAB; INTERLEUKIN 4; MESALAZINE; SALAZOSULFAPYRIDINE; TACROLIMUS;

ABDOMINAL PAIN; ADULT; ANEMIA; ARTICLE; CASE REPORT; CECUM; CELL INFILTRATION; COLON POUCH; COLON RESECTION; COLONOSCOPY; COMPUTER ASSISTED TOMOGRAPHY; DISEASE EXACERBATION; DUODENITIS; DUODENUM; EDEMA; ENDOSCOPY; EPIGASTRIC PAIN; ESOPHAGOGASTRODUODENOSCOPY; FEMALE; HEMATOCHEZIA; HISTOLOGY; HUMAN; ILEITIS; ILEOSTOMY; ILEUM; INTESTINAL BLEEDING; INTESTINE ANASTOMOSIS; NEUTROPHIL; PRIORITY JOURNAL; PROCTOCOLECTOMY; PUS; RECTUM; TH1 CELL; TH2 CELL; ULCERATIVE COLITIS; VOMITING;

ADULT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; BIOPSY; COLITIS, ULCERATIVE; COLONIC POUCHES; DIGESTIVE SYSTEM SURGICAL PROCEDURES; DUODENITIS; DUODENUM; ENDOSCOPY, DIGESTIVE SYSTEM; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; ILEOSTOMY; POUCHITIS; PROCTOCOLECTOMY, RESTORATIVE; RECURRENCE; TH1 CELLS; TH2 CELLS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 77954424088     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-009-0910-5     Document Type: Article

References (16)

1. JW Thompson JA Bargen 1960 Ulcerative duodenitis and chronic ulcerative colitis: report of two cases Gastroenterology 38 452 455 13838088
2. R Valdez HD Appleman MP Bronner 2000 Diffuse duodenitis associated with ulcerative colitis Am J Surg Pathol 24 1407 1413 10.1097/00000478-200010000- 00011 1:STN:280:DC%2BD3cvmvVansg%3D%3D 11023103
3. S Terashima Y Hoshino N Kanzaki M Kogure M Gotoh 2001 Ulcerative duodenitis accompanying ulcerative colitis J Clin Gastroenterol 32 172 175 10.1097/00004836-200102000-00018 1:STN:280:DC%2BD3M3jt1Gitg%3D%3D 11205658 (Pubitemid 32113252)
4. H Ikeuchi K Hori T Nishigami H Nakano M Uchino M Nakamura N Kaibe M Noda H Yanagi T Yamamura 2006 Diffuse gastroduodenitis and pouchitis associated with ulcerative colitis World J Gastroenterol 12 5913 5915 17007066 (Pubitemid 44594268)
5. K Kawai T Watanabe H Nakayama I Roberts-Thomson H Nagawa 2005 Image of interest. Gastrointestinal: small bowel inflammation and ulcerative colitis J Gastroenterol Hepatol 20 1791 10.1111/j.1440-1746.2005.04162.x 1:STN:280:DC%2BD2MrmvFCqsg%3D%3D 16246204 (Pubitemid 43961091)
6. AJ Bell AB Price A Forbes PJ Ciclitira C Groves RJ Nicholls 2006 Pre-pouch ileitis: a disease of the ileum in ulcerative colitis after restorative panctocolectomy Colorectal Dis 8 402 410 10.1111/j.1463-1318.2006. 00954.x 1:STN:280:DC%2BD283lvF2hsw%3D%3D 16684084 (Pubitemid 43676655)
7. J Rubenstein A Sherif H Appelman WD Chey 2004 Ulcerative colitis-associated enteritis: is ulcerative colitis always confined to the colon? J Clin Gastroenterol 38 46 51 10.1097/00004836-200401000-00011 14679327 (Pubitemid 37549268)
8. K Hori H Ikeuchi H Nakano M Uchino T Tomita Y Ohda N Hida T Matsumoto Y Fukuda H Miwa 2008 Gastroduodenitis associated with ulcerative colitis J Gastroenterol 43 193 201 10.1007/s00535-007-2143-8 18373161 (Pubitemid 351486680)
9. IR Gooding R Springall IC Talbot DB Silk 2008 Idiopathic small-intestinal inflammation after colectomy for ulcerative colitis Clin Gastroenterol Hepatol 6 707 709 10.1016/j.cgh.2008.02.031 18467187
10. A Kohn M Daperno A Armuzzi M Cappello L Biancone A Orlando A Viscido V Annese G Riegler G Meucci M Marrollo R Sostegni A Gasbarrini S Peralta C Prantera 2007 Infliximab in severe ulcerative colitis: short-term results of different infusion regimens and long-term follow-up Alimen Pharmacol Ther 6 747 756 (Pubitemid 47246204)
11. P Rutgeerts WJ Sandborn BG Feagan W Reinisch A Olson J Johanns S Travers D Rachmilewitz SB Hanauer GR Lichtenstein WJ de Villiers D Present BE Sands JF Colombel 2005 Infliximab for induction and maintenance therapy for ulcerative colitis N Engl J Med 353 2462 2476 10.1056/NEJMoa050516 1:CAS:528: DC%2BD2MXhtlShurjE 16339095 (Pubitemid 41770166)
12. T ten Hove C van Montfrans MP Peppelenbosch SJ van Deventer 2002 Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease Gut 50 206 211 10.1136/gut.50.2.206 1:CAS:528: DC%2BD38XhtFWrsbk%3D 11788561 (Pubitemid 34087933)
13. K Kasahara H Nakase N Uza S Ueno M Matsuura S Mikami S Inoue T Chiba 2007 Administration of PEG-interferon to a patient with ulcerative colitis and chronic hepatitis C correlated with reduced colonic inflammation and reversal of peripheral Th1/Th2 ratios Case Rep Gastroenterol 1 157 161 10.1159/000112654
14. Matsumura K, Nakase H, Yamamoto S, Yoshino T, Takeda Y, Kasahara K, Ueno S, Uza N, Chiba T. Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with flare-up of ulcerative colitis. Inflamm Bowel Dis. 2008; (Epub ahead of print).
15. Takeda Y, Nakase H, Namba K, Inoue S, Ueno S, Uza N, Chiba T. Up-regulation of T-bet and tight junction molecules by Bifidobactrium longum improves colonic inflammation of ulcerative colitis. Inflamm Bowel Dis (in press).
16. B Shen H Wu F Remzi R Lopez L Shen V Fazio 2009 Diagnostic value of esophagogastroduodenoscopy in patients with ileal pouch-anal anastomosis Inflamm Bowel Dis 15 395 401 10.1002/ibd.20771 18972552