MTA1-mediated transcriptional repression of SMAD7 in breast cancer cell lines

European Journal of Cancer

Volumn 49, Issue 2, 2013, Pages 492-499

  Salot, Shimul ^a,b   Gude, Rajiv ^a,b  

^a Gude Lab   (India)

^b TATA MEMORIAL HOSPITAL   (India)

Author keywords

Breast cancer; Metastasis; MTA1; SMAD7; TGFbeta

Indexed keywords

BETA6 INTEGRIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; METASTASIS ASSOCIATED 1 PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SHORT HAIRPIN RNA; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CARCINOGENESIS; CONTROLLED STUDY; DEACETYLATION; ENZYME ACTIVATION; GENE INACTIVATION; HUMAN; HUMAN CELL; METASTASIS; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEACETYLASES; HUMANS; MCF-7 CELLS; REPRESSOR PROTEINS; SMAD7 PROTEIN; TRANSCRIPTION, GENETIC;

EID: 84872121742     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.06.019     Document Type: Article

References (47)

1. A.F. Chambers, A.C. Groom, and I.C. MacDonald Dissemination and growth of cancer cells in metastatic sites Nat Rev Cancer 2 2002 563 572
2. Y. Toh, S.D. Pencil, and G.L. Nicolson A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses J Biol Chem 269 1994 22958 22963
3. Y. Toh, S.D. Pencil, and G.L. Nicolson Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines Gene 159 1995 97 104
4. H. Sasaki, S. Moriyama, and Y. Nakashima Expression of the MTA1 mRNA in advanced lung cancer Lung cancer 35 2002 149 154
5. H. Sasaki, H. Yukiue, and Y. Kobayashi Expression of the MTA1 mRNA in thymoma patients Cancer Lett 174 2001 159 163
6. S. Balasenthil, R.R. Broaddus, and R. Kumar Expression of metastasis-associated protein 1 (MTA1) in benign endometrium and endometrial adenocarcinomas Hum Pathol 37 2006 656 661
7. Y. Toh, H. Kuwano, M. Mori, G.L. Nicolson, and K. Sugimachi Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas Br J Cancer 79 1999 1723 1726
8. Y. Toh, E. Oki, and S. Oda Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis Int J Cancer 74 1997 459 463
9. G. Kawasaki, S. Yanamoto, I. Yoshitomi, S. Yamada, and A. Mizuno Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: correlation with metastasis and invasion Int J Oral Maxillofac Surg 2008
10. S.H. Li, H. Tian, and W.M. Yue Overexpression of metastasis-associated protein 1 is significantly correlated with tumor angiogenesis and poor survival in patients with early-stage non-small cell lung cancer Ann Surg Oncol 18 2011 2048 2056
11. K.S. Jang, S.S. Paik, H. Chung, Y.H. Oh, and G. Kong MTA1 overexpression correlates significantly with tumor grade and angiogenesis in human breast cancers Cancer Sci 97 2006 374 379
12. M.D. Martin, S.G. Hilsenbeck, and S.K. Mohsin Breast tumors that overexpress nuclear metastasis-associated 1 (MTA1) protein have high recurrence risks but enhanced responses to systemic therapies Breast Cancer Res Treat 95 2006 7 12
13. M.D. Martin, K. Fischbach, and C.K. Osborne Loss of heterozygosity events impeding breast cancer metastasis contain the MTA1 gene Cancer Res 61 2001 3578 3580
14. A.E. Gururaj, C. Holm, G. Landberg, and R. Kumar Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer Cell Cycle 5 2006 1407 1410
15. Y. Xue, J. Wong, and G.T. Moreno NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities Mol Cell 2 1998 851 861
16. S. Balasenthil, A.E. Gururaj, and A.H. Talukder Identification of Pax5 as a target of MTA1 in B-cell lymphomas Cancer Res 67 2007 7132 7138
17. B. Manavathi, S. Peng, and S.K. Rayala Repression of Six3 by a corepressor regulates rhodopsin expression Proc Natl Acad Sci U S A 104 2007 13128 13133
18. A. Mazumdar, R.A. Wang, and S.K. Mishra Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor Nat Cell Biol 3 2001 30 37
19. R. Kumar, S. Balasenthil, and S.B. Pakala Metastasis-associated protein 1 short form stimulates Wnt1 pathway in mammary epithelial and cancer cells Cancer Res 70 2010 6598 6608
20. Y. Shi, and J. Massague Mechanisms of TGF-beta signaling from cell membrane to the nucleus Cell 113 2003 685 700
21. A. Moustakas, S. Souchelnytskyi, and C.H. Heldin Smad regulation in TGF-beta signal transduction J Cell Sci 114 2001 4359 4369
22. P. ten Dijke, and C.S. Hill New insights into TGF-beta-Smad signalling Trends Biochem Sci 29 2004 265 273
23. X. Yan, Z. Liu, and Y. Chen Regulation of TGF-beta signaling by Smad7 Acta Biochim Biophys Sin (Shanghai) 41 2009 263 272
24. B. Wang, A. Omar, and T. Angelovska Regulation of collagen synthesis by inhibitory Smad7 in cardiac myofibroblasts Am J Physiol Heart Circ Physiol 293 2007 H1282 1290
25. H.Y. Lan Smad7 as a therapeutic agent for chronic kidney diseases Front Biosci 13 2008 4984 4992
26. A.C. Chung, X.R. Huang, and L. Zhou Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice Nephrol Dial Transplant 24 2009 1443 1454
27. W. Wang, X.R. Huang, and A.G. Li Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7 J Am Soc Nephrol 16 2005 1371 1383
28. G. Monteleone, F. Pallone, and T.T. MacDonald Smad7 in TGF-beta-mediated negative regulation of gut inflammation Trends Immunol 25 2004 513 517
29. J.M. Cerutti, K.N. Ebina, and S.E. Matsuo Expression of Smad4 and Smad7 in human thyroid follicular carcinoma cell lines J Endocrinol Invest 26 2003 516 521
30. M. Mikula, V. Proell, A.N. Fischer, and W. Mikulits Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion J Cell Physiol 209 2006 560 567
31. S.C. Dowdy, A. Mariani, and M.M. Reinholz Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer Gynecol Oncol 96 2005 368 373
32. N.E. Buckley, A.M. Hosey, and J.J. Gorski BRCA1 regulates IFN-gamma signaling through a mechanism involving the type I IFNs Mol Cancer Res 5 2007 261 270
33. A.H. Talukder, S.K. Mishra, and M. Mandal MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions J Biol Chem 278 2003 11676 11685
34. A.H. Talukder, A. Gururaj, S.K. Mishra, R.K. Vadlamudi, and R. Kumar Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator Mol Cell Biol 24 2004 6581 6591
35. Y. Aramaki, K. Ogawa, and Y. Toh Direct interaction between metastasis-associated protein 1 and endophilin 3 FEBS Lett 579 2005 3731 3736
36. S.K. Mishra, A. Mazumdar, and R.K. Vadlamudi MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions J Biol Chem 278 2003 19209 19219
37. M.A. Khaleque, A. Bharti, and J. Gong Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1 Oncogene 27 2008 1886 1893
38. C.H. Heldin, and A. Moustakas Role of Smads in TGFbeta signaling Cell Tissue Res 347 2012 21 36
39. J. Massague TGFbeta in Cancer Cell 134 2008 215 230
40. J.J. Yin, K. Selander, and J.M. Chirgwin TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development J Clin Invest 103 1999 197 206
41. D. Javelaud, K.S. Mohammad, and C.R. McKenna Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis Cancer Res 67 2007 2317 2324
42. I.J. Fidler Blockade of the TGF-beta superfamily by Smad7: breaking a link in the metastatic chain J Natl Cancer Inst 97 2005 1714 1715
43. G.L. Nicolson, A. Nawa, and Y. Toh Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation Clin Exp Metastasis 20 2003 19 24
44. H. Qian, J. Yu, and Y. Li RNA interference of metastasis-associated gene 1 inhibits metastasis of B16F10 melanoma cells in a C57BL/6 mouse model Biol Cell 99 2007 573 581
45. S.B. Pakala, K. Singh, and S.D. Reddy TGF-beta1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells Oncogene 30 2011 2230 2241
46. M. Kidd, I.M. Modlin, and R. Pfragner Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1 Cancer 109 2007 2420 2431
47. S. Salot, and R. Gude MTA1 Aids the AKT Pathway by Inhibiting Expression of a Key Regulator, PTEN J Can Sci Ther 2 4 2010 114 119