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Volumn 2, Issue 4, 2010, Pages 114-119

MTA1 aids the AKT pathway by inhibiting expression of a key regulator, PTEN

Author keywords

AKT; Breast cancer; Histone deacetylation; Metastasis; MTA1; PI3K; PTEN

Indexed keywords

CALVASCULIN; HISTONE DEACETYLASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMALL INTERFERING RNA;

EID: 77954961890     PISSN: None     EISSN: 19485956     Source Type: Journal    
DOI: 10.4172/1948-5956.1000034     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein inase which phosphorylates and activates protein kinase Balpha
    • Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, et al. (1997) Characterization of a 3-phosphoinositide-dependent protein inase which phosphorylates and activates protein kinase Balpha. Curr Biol 7: 261-269.
    • (1997) Curr Biol , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5
  • 2
    • 21244446273 scopus 로고    scopus 로고
    • Direct interaction between metastasis-associated protein 1 and endophilin 3
    • Aramaki Y, Ogawa K, Toh Y, Ito T, Akimitsu N, et al. (2005) Direct interaction between metastasis-associated protein 1 and endophilin 3. FEBS Lett 579: 3731-3736.
    • (2005) FEBS Lett , vol.579 , pp. 3731-3736
    • Aramaki, Y.1    Ogawa, K.2    Toh, Y.3    Ito, T.4    Akimitsu, N.5
  • 3
    • 33745442538 scopus 로고    scopus 로고
    • Expression of metastasisassociated protein 1 (MTA1) in benign endometrium and endometrial adenocarcinomas
    • Balasenthil S, Broaddus RR, Kumar R (2006) Expression of metastasisassociated protein 1 (MTA1) in benign endometrium and endometrial adenocarcinomas. Hum Pathol 37: 656-661.
    • (2006) Hum Pathol , vol.37 , pp. 656-661
    • Balasenthil, S.1    Broaddus, R.R.2    Kumar, R.3
  • 5
    • 0032560796 scopus 로고    scopus 로고
    • Akt activation by growth factors is a multiple-step process: The role of the PH domain
    • Bellacosa A, Chan TO, Ahmed NN, Datta K, Malstrom S, et al. (1998) Akt activation by growth factors is a multiple-step process: the role of the PH domain. Oncogene 17: 313-325.
    • (1998) Oncogene , vol.17 , pp. 313-325
    • Bellacosa, A.1    Chan, T.O.2    Ahmed, N.N.3    Datta, K.4    Malstrom, S.5
  • 6
    • 17844385784 scopus 로고    scopus 로고
    • Regulatory cross-talk between lysine acetylation and ubiquitination: Role in the control of protein stability
    • Caron C, Boyault C, Khochbin S (2005) Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability. Bioessays 27: 408-415.
    • (2005) Bioessays , vol.27 , pp. 408-415
    • Caron, C.1    Boyault, C.2    Khochbin, S.3
  • 7
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers AF, Groom AC, MacDonald IC (2002) Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2: 563-572.
    • (2002) Nat Rev Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    Macdonald, I.C.3
  • 8
    • 33746653428 scopus 로고    scopus 로고
    • Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer
    • Gururaj AE, Holm C, Landberg G, Kumar R (2006a) Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer. Cell Cycle 5: 1407-1410.
    • (2006) Cell Cycle , vol.5 , pp. 1407-1410
    • Gururaj, A.E.1    Holm, C.2    Landberg, G.3    Kumar, R.4
  • 10
    • 33645550355 scopus 로고    scopus 로고
    • MTA1 overexpression correlates significantly with tumor grade and angiogenesis in human breast cancers
    • Jang KS, Paik SS, Chung H, Oh YH, Kong G (2006) MTA1 overexpression correlates significantly with tumor grade and angiogenesis in human breast cancers. Cancer Sci 97: 374-379.
    • (2006) Cancer Sci , vol.97 , pp. 374-379
    • Jang, K.S.1    Paik, S.S.2    Chung, H.3    Oh, Y.H.4    Kong, G.5
  • 11
    • 55249083025 scopus 로고    scopus 로고
    • Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: Correlation with metastasis and invasion
    • Kawasaki G, Yanamoto S, Yoshitomi I, Yamada S, Mizuno A (2008) Overexpression of metastasis-associated MTA1 in oral squamous cell carcinomas: correlation with metastasis and invasion. Int J Oral Maxillofac Surg 37: 1039-1046.
    • (2008) Int J Oral Maxillofac Surg , vol.37 , pp. 1039-1046
    • Kawasaki, G.1    Yanamoto, S.2    Yoshitomi, I.3    Yamada, S.4    Mizuno, A.5
  • 12
    • 41149083495 scopus 로고    scopus 로고
    • Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1
    • Khaleque MA, Bharti A, Gong J, Gray PJ, Sachdev V, et al. (2008) Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1. Oncogene 27: 1886-1893.
    • (2008) Oncogene , vol.27 , pp. 1886-1893
    • Khaleque, M.A.1    Bharti, A.2    Gong, J.3    Gray, P.J.4    Sachdev, V.5
  • 13
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, Podsypanina K, Bose S, et al. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275: 1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypanina, K.4    Bose, S.5
  • 14
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T, Dixon JE (1998) The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 16
    • 0035328865 scopus 로고    scopus 로고
    • Loss of heterozygosity events impeding breast cancer metastasis contain the MTA1 gene
    • Martin MD, Fischbach K, Osborne CK, Mohsin SK, Allred DC, et al. (2001) Loss of heterozygosity events impeding breast cancer metastasis contain the MTA1 gene. Cancer Res 61: 3578-3580.
    • (2001) Cancer Res , vol.61 , pp. 3578-3580
    • Martin, M.D.1    Fischbach, K.2    Osborne, C.K.3    Mohsin, S.K.4    Allred, D.C.5
  • 17
    • 32444434471 scopus 로고    scopus 로고
    • Breast tumors that overexpress nuclear metastasis-associated 1 (MTA1) protein have high recurrence risks but enhanced responses to systemic therapies
    • Martin MD, Hilsenbeck SG, Mohsin SK, Hopp TA, Clark GM, et al. (2006) Breast tumors that overexpress nuclear metastasis-associated 1 (MTA1) protein have high recurrence risks but enhanced responses to systemic therapies. Breast Cancer Res Treat 95: 7-12.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 7-12
    • Martin, M.D.1    Hilsenbeck, S.G.2    Mohsin, S.K.3    Hopp, T.A.4    Clark, G.M.5
  • 18
    • 0037805635 scopus 로고    scopus 로고
    • MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions
    • Mishra SK, Mazumdar A, Vadlamudi RK, Li F, Wang RA, et al. (2003) MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions. J Biol Chem 278: 19209-19219.
    • (2003) J Biol Chem , vol.278 , pp. 19209-19219
    • Mishra, S.K.1    Mazumdar, A.2    Vadlamudi, R.K.3    Li, F.4    Wang, R.A.5
  • 19
    • 52449130697 scopus 로고    scopus 로고
    • Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas
    • Pinto M, Vieira J, Ribeiro FR, Soares MJ, Henrique R, et al. (2008) Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas. Cell Oncol 30: 389-395.
    • (2008) Cell Oncol , vol.30 , pp. 389-395
    • Pinto, M.1    Vieira, J.2    Ribeiro, F.R.3    Soares, M.J.4    Henrique, R.5
  • 20
    • 37549020704 scopus 로고    scopus 로고
    • Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
    • Saal LH, Gruvberger-Saal SK, Persson C, Lovgren K, Jumppanen M, et al. (2008) Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nat Genet 40: 102-107.
    • (2008) Nat Genet , vol.40 , pp. 102-107
    • Saal, L.H.1    Gruvberger-Saal, S.K.2    Persson, C.3    Lovgren, K.4    Jumppanen, M.5
  • 23
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, et al. (1998) Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95: 29-39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    de la Pompa, J.L.3    Brothers, G.M.4    Mirtsos, C.5
  • 24
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, et al. (1997) Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15: 356-362.
    • (1997) Nat Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3    Yung, W.K.4    Lin, H.5
  • 25
    • 0030799706 scopus 로고    scopus 로고
    • Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
    • Stokoe D, Stephens LR, Copeland T, Gaffney PR, Reese CB, et al. (1997) Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277: 567-570.
    • (1997) Science , vol.277 , pp. 567-570
    • Stokoe, D.1    Stephens, L.R.2    Copeland, T.3    Gaffney, P.R.4    Reese, C.B.5
  • 26
    • 3242689606 scopus 로고    scopus 로고
    • Metastasisassociated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator
    • Talukder AH, Gururaj A, Mishra SK, Vadlamudi RK, Kumar R (2004) Metastasisassociated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator. Mol Cell Biol 24: 6581-6591.
    • (2004) Mol Cell Biol , vol.24 , pp. 6581-6591
    • Talukder, A.H.1    Gururaj, A.2    Mishra, S.K.3    Vadlamudi, R.K.4    Kumar, R.5
  • 27
    • 0013294458 scopus 로고    scopus 로고
    • MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions
    • Talukder AH, Mishra SK, Mandal M, Balasenthil S, Mehta S, et al. (2003) MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions. J Biol Chem 278: 11676-11685.
    • (2003) J Biol Chem , vol.278 , pp. 11676-11685
    • Talukder, A.H.1    Mishra, S.K.2    Mandal, M.3    Balasenthil, S.4    Mehta, S.5
  • 28
    • 0032999309 scopus 로고    scopus 로고
    • Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas
    • Toh Y, Kuwano H, Mori M, Nicolson GL, Sugimachi K (1999) Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas. Br J Cancer 79: 1723-1726.
    • (1999) Br J Cancer , vol.79 , pp. 1723-1726
    • Toh, Y.1    Kuwano, H.2    Mori, M.3    Nicolson, G.L.4    Sugimachi, K.5
  • 29
    • 0030863876 scopus 로고    scopus 로고
    • Overexpression of the MTA1 gene in gastrointestinal carcinomas: Correlation with invasion and metastasis
    • Toh Y, Oki E, Oda S, Tokunaga E, Ohno S, et al. (1997) Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis. Int J Cancer 74: 459-463.
    • (1997) Int J Cancer , vol.74 , pp. 459-463
    • Toh, Y.1    Oki, E.2    Oda, S.3    Tokunaga, E.4    Ohno, S.5
  • 30
    • 0027978984 scopus 로고
    • A novel candidate metastasisassociated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses
    • Toh Y, Pencil SD, Nicolson GL (1994) A novel candidate metastasisassociated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. J Biol Chem 269: 22958-22963.
    • (1994) J Biol Chem , vol.269 , pp. 22958-22963
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 31
    • 0029029343 scopus 로고
    • Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines
    • Toh Y, Pencil SD, Nicolson GL (1995) Analysis of the complete sequence of the novel metastasis-associated candidate gene, mta1, differentially expressed in mammary adenocarcinoma and breast cancer cell lines. Gene 159: 97-104.
    • (1995) Gene , vol.159 , pp. 97-104
    • Toh, Y.1    Pencil, S.D.2    Nicolson, G.L.3
  • 32
    • 34249905439 scopus 로고    scopus 로고
    • Overexpression of fascin-1 in advanced colorectal adenocarcinoma: Tissue microarray analysis of immunostaining scores with clinicopathological parameters
    • Tsai WC, Chao YC, Sheu LF, Chang JL, Nieh S, et al. (2007) Overexpression of fascin-1 in advanced colorectal adenocarcinoma: tissue microarray analysis of immunostaining scores with clinicopathological parameters. Dis Markers 23: 153-160.
    • (2007) Dis Markers , vol.23 , pp. 153-160
    • Tsai, W.C.1    Chao, Y.C.2    Sheu, L.F.3    Chang, J.L.4    Nieh, S.5
  • 33
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck B, Alessi DR (2000) The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 346 Pt 3: 561-576.
    • (2000) Biochem J 346 Pt , vol.3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 34
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2: 489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 35
    • 0032252209 scopus 로고    scopus 로고
    • NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
    • Xue Y, Wong J, Moreno GT, Young MK, Cote J, et al. (1998) NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol Cell 2: 851-861.
    • (1998) Mol Cell , vol.2 , pp. 851-861
    • Xue, Y.1    Wong, J.2    Moreno, G.T.3    Young, M.K.4    Cote, J.5
  • 36
    • 0142211208 scopus 로고    scopus 로고
    • The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity
    • Yao YL, Yang WM (2003) The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity. J Biol Chem 278: 42560-42568.
    • (2003) J Biol Chem , vol.278 , pp. 42560-42568
    • Yao, Y.L.1    Yang, W.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.