Functional imaging of legumain in cancer using a new quenched activity-based probe

Journal of the American Chemical Society

Volumn 135, Issue 1, 2013, Pages 174-182

  Edgington, Laura E ^a   Verdoes, Martijn ^a   Ortega, Alberto ^a   Withana, Nimali P ^a   Lee, Jiyoun ^a,b   Syed, Salahuddin ^a   Bachmann, Michael H ^a   Blum, Galia ^a,b,c   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Sungshin Women's University   (South Korea)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED MACROPHAGES; ACTIVITY-BASED PROBE; BIOLOGICAL FUNCTIONS; CANCER PROGRESSION; CYSTEINE PROTEASE; FUNCTIONAL IMAGING; HIGHLY-CORRELATED; HUMAN CANCER; INFLAMMATORY DISEASE; MACROPHAGE ACTIVATION; METASTATIC LESIONS; MOUSE MODELS; TUMOR MICROENVIRONMENT; TUMORIGENESIS; WHOLE CELL;

AMINO ACIDS; DISEASES; MACROPHAGES; PATHOLOGY; TUMORS;

PROBES;

LEGUMAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; METASTASIS; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANIMALS; CELL LINE; CYSTEINE ENDOPEPTIDASES; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT DYES; HUMANS; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NEOPLASMS, EXPERIMENTAL;

EID: 84872113307     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja307083b     Document Type: Article

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