-
1
-
-
0027468145
-
The biochemistry and cell biology of antigen processing and presentation
-
Germain, R.N. & Margulies, D.H. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11, 403-450 (1993).
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 403-450
-
-
Germain, R.N.1
Margulies, D.H.2
-
2
-
-
0029615496
-
How MHC class II molecules acquire peptide cargo: Biosynthesis and trafficking through the endocytic pathway
-
Wolf, P.R. & Ploegh, H.L. How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway. Annu. Rev. Cell Cev. Biol. 11, 267-306 (1995).
-
(1995)
Annu. Rev. Cell Cev. Biol.
, vol.11
, pp. 267-306
-
-
Wolf, P.R.1
Ploegh, H.L.2
-
3
-
-
0030028779
-
Invariant chain structure and MHC class II function
-
Cresswell, P. Invariant chain structure and MHC class II function. Cell 84, 505-507 (1996).
-
(1996)
Cell
, vol.84
, pp. 505-507
-
-
Cresswell, P.1
-
4
-
-
0030937833
-
Capture and processing of exogenous antigens for presentation on MHC molecules
-
Watts, C. Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 15, 821-850 (1997).
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 821-850
-
-
Watts, C.1
-
5
-
-
0028344533
-
Structure of peptides associated with class I and class II MHC molecules
-
Engelhard, V.H. Structure of peptides associated with class I and class II MHC molecules. Annu. Rev. Immunol. 12, 181-207 (1994).
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 181-207
-
-
Engelhard, V.H.1
-
6
-
-
0036467586
-
Trafficking of MHC class II molecules in the late secretory pathway
-
Hiltbold, E.M. & Roche, P.A. Trafficking of MHC class II molecules in the late secretory pathway. Curr. Opin. Immunol. 14, 30-35 (2002).
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 30-35
-
-
Hiltbold, E.M.1
Roche, P.A.2
-
7
-
-
0026505030
-
Irreversible association of peptides with class II MHC molecules in living cells
-
Lanzavecchia, A., Reid, P.A. & Watts, C. Irreversible association of peptides with class II MHC molecules in living cells. Nature 357, 249-252 (1992).
-
(1992)
Nature
, vol.357
, pp. 249-252
-
-
Lanzavecchia, A.1
Reid, P.A.2
Watts, C.3
-
8
-
-
0036227429
-
Diversity in MHC class II antigen presentation
-
Robinson, J.H. & Delvig, A.A. Diversity in MHC class II antigen presentation. Immunology 105, 252-262 (2002).
-
(2002)
Immunology
, vol.105
, pp. 252-262
-
-
Robinson, J.H.1
Delvig, A.A.2
-
9
-
-
0026587182
-
Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E
-
Bennett, K. et al. Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E. Eur. J. Immunol. 22, 1519-1524 (1992).
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 1519-1524
-
-
Bennett, K.1
-
10
-
-
0033592902
-
Extracellular antigen processing and presentation by immature dendritic cells
-
Santambrogio, L. et al. Extracellular antigen processing and presentation by immature dendritic cells. Proc. Natl. Acad. Sci. USA 96, 15056-15061 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 15056-15061
-
-
Santambrogio, L.1
-
11
-
-
0347362810
-
Differential processing of CD4 T-cell epitopes from the protective antigen of Bacillus anthracis
-
Musson, J.A., Walker, N., Flick-Smith, H., Williamson, E.D. & Robinson, J.H. Differential processing of CD4 T-cell epitopes from the protective antigen of Bacillus anthracis. J. Biol. Chem. 278, 52425-52431 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52425-52431
-
-
Musson, J.A.1
Walker, N.2
Flick-Smith, H.3
Williamson, E.D.4
Robinson, J.H.5
-
12
-
-
0035145332
-
Antigen processing in the endocytic compartment
-
Watts, C. Antigen processing in the endocytic compartment. Curr. Opin. Immunol. 13, 26-31 (2001).
-
(2001)
Curr. Opin. Immunol.
, vol.13
, pp. 26-31
-
-
Watts, C.1
-
13
-
-
0037805704
-
Lysosomal cysteine proteases regulate antigen presentation
-
Honey, K. & Rudensky, A.Y. Lysosomal cysteine proteases regulate antigen presentation. Nat. Rev. Immunol. 3, 472-482 (2003).
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 472-482
-
-
Honey, K.1
Rudensky, A.Y.2
-
14
-
-
1042278900
-
Class II MHC peptide loading by the professionals
-
Bryant, P. & Ploegh, H. Class II MHC peptide loading by the professionals. Curr. Opin. Immunol. 16, 96-102 (2004).
-
(2004)
Curr. Opin. Immunol.
, vol.16
, pp. 96-102
-
-
Bryant, P.1
Ploegh, H.2
-
15
-
-
0011720253
-
Role for intracellular proteases in the processing and transport of class II HLA antigens
-
Blum, J.S. & Cresswell, P. Role for intracellular proteases in the processing and transport of class II HLA antigens. Proc. Natl. Acad. Sci. USA 85, 3975-3979 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 3975-3979
-
-
Blum, J.S.1
Cresswell, P.2
-
16
-
-
0028922618
-
Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles
-
Amigorena, S. et al. Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles. J. Exp. Med. 181, 1729-1741 (1995).
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1729-1741
-
-
Amigorena, S.1
-
17
-
-
0037396716
-
Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone
-
Manoury, B. et al. Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone. Immunity 18, 489-498 (2003).
-
(2003)
Immunity
, vol.18
, pp. 489-498
-
-
Manoury, B.1
-
18
-
-
0029931108
-
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading
-
Riese, R.J. et al. Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading. Immunity 4, 357-366 (1996).
-
(1996)
Immunity
, vol.4
, pp. 357-366
-
-
Riese, R.J.1
-
19
-
-
0030985764
-
Li chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes
-
Brachet, V., Raposo, G., Amigorena, S. & Mellman, I. li chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes. J. Cell. Biol. 137, 51-65 (1997).
-
(1997)
J. Cell. Biol.
, vol.137
, pp. 51-65
-
-
Brachet, V.1
Raposo, G.2
Amigorena, S.3
Mellman, I.4
-
20
-
-
0033571691
-
Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells
-
Driessen, C. et al. Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. J. Cell. Biol. 147, 775-790 (1999).
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 775-790
-
-
Driessen, C.1
-
21
-
-
0032540474
-
Cathepsin L: Critical role in li degradation and CD4 T cell selection in the thymus
-
Nakagawa, T. et al. Cathepsin L: critical role in li degradation and CD4 T cell selection in the thymus. Science 280, 450-453 (1998).
-
(1998)
Science
, vol.280
, pp. 450-453
-
-
Nakagawa, T.1
-
22
-
-
0141831692
-
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis
-
Tolosa, E. et al. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J. Clin. Invest. 112, 517-526 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 517-526
-
-
Tolosa, E.1
-
23
-
-
0038651151
-
Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs
-
Bahia, J. et al. Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs. Proc. Natl. Acad. Sci. USA 100, 6664-6669 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6664-6669
-
-
Bahia, J.1
-
24
-
-
0034599498
-
Role for cathepsin F in invariant chain processing and major Histocompatibility complex class II peptide loading by macrophages
-
Shi, G.P. et al. Role for cathepsin F in invariant chain processing and major Histocompatibility complex class II peptide loading by macrophages. J. Exp. Med. 191, 1177-1185 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1177-1185
-
-
Shi, G.P.1
-
25
-
-
0036329099
-
Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity
-
Saegusa, K. et al. Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity. J. Clin. Invest. 110, 361-369 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 361-369
-
-
Saegusa, K.1
-
26
-
-
0032103322
-
Cathepsin S activity regulates antigen presentation and immunity
-
Riese, R.J. et al. Cathepsin S activity regulates antigen presentation and immunity. J. Clin. Invest. 101, 2351-2363 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2351-2363
-
-
Riese, R.J.1
-
27
-
-
2442549710
-
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice
-
Nakagawa, T.Y. et al. Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice. Immunity 10, 207-217 (1999).
-
(1999)
Immunity
, vol.10
, pp. 207-217
-
-
Nakagawa, T.Y.1
-
28
-
-
0030790341
-
Degradation of mouse invariant chain: Roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism
-
Villadangos, J.A., Riese, R.J., Peters, C., Chapman, H.A. & Ploegh, H.L. Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism. J. Exp. Med. 188, 549-560 (1997).
-
(1997)
J. Exp. Med.
, vol.188
, pp. 549-560
-
-
Villadangos, J.A.1
Riese, R.J.2
Peters, C.3
Chapman, H.A.4
Ploegh, H.L.5
-
29
-
-
20244366658
-
Antigen processing and presentation in human muscle: Cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies
-
Wiendl, H. et al. Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies. J. Neuroimmunol. 138, 132-143 (2003).
-
(2003)
J. Neuroimmunol.
, vol.138
, pp. 132-143
-
-
Wiendl, H.1
-
30
-
-
0037022599
-
Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity
-
Matza, D. et al. Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity. Proc. Natl. Acad. Sci. USA 99, 3018-3023 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3018-3023
-
-
Matza, D.1
-
31
-
-
0038401145
-
Invariant chain, a chain of command
-
Matza, D., Kerem, A. & Shachar, I. Invariant chain, a chain of command. Trends Immunol. 24, 264-268 (2003).
-
(2003)
Trends Immunol.
, vol.24
, pp. 264-268
-
-
Matza, D.1
Kerem, A.2
Shachar, I.3
-
32
-
-
0033083688
-
Cathepsin S required for normal MHC class II peptide loading and germinal center development
-
Shi, G.P. et al. Cathepsin S required for normal MHC class II peptide loading and germinal center development. Immunity 10, 197-206 (1999).
-
(1999)
Immunity
, vol.10
, pp. 197-206
-
-
Shi, G.P.1
-
33
-
-
0028981178
-
HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading
-
Denzin, L.K. & Cresswell, P. HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82, 155-165 (1995).
-
(1995)
Cell
, vol.82
, pp. 155-165
-
-
Denzin, L.K.1
Cresswell, P.2
-
34
-
-
0029072047
-
Mediation by HLA-DM of dissociation of peptides from HLA-DR
-
Sloan, V.S. et al. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375, 802-806 (1995).
-
(1995)
Nature
, vol.375
, pp. 802-806
-
-
Sloan, V.S.1
-
35
-
-
0029084023
-
DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
-
Sherman, M.A., Weber, D.A. & Jensen, P.E. DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity 3, 197-205 (1995).
-
(1995)
Immunity
, vol.3
, pp. 197-205
-
-
Sherman, M.A.1
Weber, D.A.2
Jensen, P.E.3
-
36
-
-
0029864967
-
Developing shedding inhibitions: How MHC class II molecules reach maturity
-
Busch, R. & Mellins, E.D. Developing and shedding inhibitions: how MHC class II molecules reach maturity. Curr. Opin. Immunol. 8, 51-58 (1996).
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 51-58
-
-
Busch, R.1
Mellins, E.D.2
-
37
-
-
0031080953
-
How HLA-DM edits the MHC class II peptide repertoire: Survival of the fittest?
-
Kropshofer, H., Hammerling, G.J. & Vogt, A.B. How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest? Immunol. Today 18, 77-82 (1997).
-
(1997)
Immunol. Today
, vol.18
, pp. 77-82
-
-
Kropshofer, H.1
Hammerling, G.J.2
Vogt, A.B.3
-
38
-
-
0034082410
-
Nonclassical MHC class II molecules
-
Alfonso, C. & Karlsson, L. Nonclassical MHC class II molecules. Annu. Rev. Immunol. 18, 113-142 (2000).
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 113-142
-
-
Alfonso, C.1
Karlsson, L.2
-
39
-
-
0036467491
-
HLA-DM, HLA-DO and tapasin: Functional similarities and differences
-
Brocke, P., Garbi, N., Momburg, F. & Hammerling, G.J. HLA-DM, HLA-DO and tapasin: functional similarities and differences. Curr. Opin. Immunol. 14, 22-29. (2002).
-
(2002)
Curr. Opin. Immunol.
, vol.14
, pp. 22-29
-
-
Brocke, P.1
Garbi, N.2
Momburg, F.3
Hammerling, G.J.4
-
40
-
-
0036838687
-
Structural factors contributing to DM susceptibility of MHC class II/peptide complexes
-
Belmares, M.P., Busch, R., Wucherpfennig, K.W., McConnell, H.M. & Mellins, E.D. Structural factors contributing to DM susceptibility of MHC class II/peptide complexes. J. Immunol. 169, 5109-5117 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 5109-5117
-
-
Belmares, M.P.1
Busch, R.2
Wucherpfennig, K.W.3
McConnell, H.M.4
Mellins, E.D.5
-
41
-
-
1642495746
-
Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain
-
Stratikos, E., Wiley, D.C. & Stern, L.J. Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain. J. Immunol. 172, 1109-1117 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 1109-1117
-
-
Stratikos, E.1
Wiley, D.C.2
Stern, L.J.3
-
42
-
-
1842633890
-
T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM
-
Pu, Z., Lovitch, S.B., Bikoff, E.K. & Unanue, E.R. T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. Immunity 20, 467-476 (2004).
-
(2004)
Immunity
, vol.20
, pp. 467-476
-
-
Pu, Z.1
Lovitch, S.B.2
Bikoff, E.K.3
Unanue, E.R.4
-
43
-
-
0028899617
-
The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent
-
Stebbins, C.C., Loss, G.E., Jr., Elias, C.G., Chervonsky, A. & Sant, A.J. The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent. J. Exp. Med. 181, 223-234 (1995).
-
(1995)
J. Exp. Med.
, vol.181
, pp. 223-234
-
-
Stebbins, C.C.1
Loss Jr., G.E.2
Elias, C.G.3
Chervonsky, A.4
Sant, A.J.5
-
44
-
-
0031665409
-
The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed
-
Wolf, P.R. et al. The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed. Eur. J. Immunol. 28, 2605-2618 (1998).
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2605-2618
-
-
Wolf, P.R.1
-
46
-
-
0037378896
-
DM loss in k haplotype mice reveals isotype-specific chaperone requirements
-
Koonce, C.H. et al. DM loss in k haplotype mice reveals isotype-specific chaperone requirements. J. Immunol. 170, 3751-3761 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 3751-3761
-
-
Koonce, C.H.1
-
47
-
-
0041429632
-
Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides
-
Pashine, A. et al. Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Immunity 19, 183-192 (2003).
-
(2003)
Immunity
, vol.19
, pp. 183-192
-
-
Pashine, A.1
-
48
-
-
0029790517
-
HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport
-
Liljedahl, M. et al. HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport. EMBO J. 15, 4817-4824 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 4817-4824
-
-
Liljedahl, M.1
-
49
-
-
0037089576
-
Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development
-
Chen, X. et al. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J. Exp. Med. 195, 1053-1062 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1053-1062
-
-
Chen, X.1
-
50
-
-
0037089675
-
Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO
-
Glazier, K.S. et al. Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO. J. Exp. Med. 195, 1063-1069 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1063-1069
-
-
Glazier, K.S.1
-
51
-
-
0033784580
-
Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice
-
Perraudeau, M. et al. Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice. Eur. J. Immunol. 30, 2871-2880 (2000).
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2871-2880
-
-
Perraudeau, M.1
-
52
-
-
20244364647
-
Altered antigen presentation in mice lacking H2-O
-
Liljedahl, M. et al. Altered antigen presentation in mice lacking H2-O. Immunity 8, 233-243 (1998).
-
(1998)
Immunity
, vol.8
, pp. 233-243
-
-
Liljedahl, M.1
-
53
-
-
0343238970
-
Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO
-
van Ham, M. et al. Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J. Exp. Med. 191, 1127-1136 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1127-1136
-
-
van Ham, M.1
-
54
-
-
0024949536
-
Processing of immunoglobulin-associated antigen in B lymphocytes
-
Watts, C., West, M.A., Reid, P.A. & Davidson, H.W. Processing of immunoglobulin-associated antigen in B lymphocytes. Cold Spring Harb. Symp. Quant. Biol. 1, 345-352 (1989).
-
(1989)
Cold Spring Harb. Symp. Quant. Biol.
, vol.1
, pp. 345-352
-
-
Watts, C.1
West, M.A.2
Reid, P.A.3
Davidson, H.W.4
-
55
-
-
0037331965
-
Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes
-
Brocke, P., Armandola, E., Garbi, N. & Hammerling, G.J. Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes. Eur. J. Immunol. 33, 411-421 (2003).
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 411-421
-
-
Brocke, P.1
Armandola, E.2
Garbi, N.3
Hammerling, G.J.4
-
56
-
-
0042430497
-
Analysis of H2-O influence on antigen presentation by B cells
-
Alfonso, C. et al. Analysis of H2-O influence on antigen presentation by B cells. J. Immunol. 171, 2331-2337 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 2331-2337
-
-
Alfonso, C.1
-
57
-
-
0027407108
-
Dominance and crypticity of T cell antigenic determinants
-
Sercarz, E.E. et al. Dominance and crypticity of T cell antigenic determinants. Annu. Rev. Immunol. 11, 729-766 (1993).
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 729-766
-
-
Sercarz, E.E.1
-
58
-
-
0343867197
-
Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcγ receptors
-
Driessen, C., Lennon-Dumenil, A.M. & Ploegh, H.L. Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcγ receptors. Eur. J. Immunol. 31, 1592-1601 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 1592-1601
-
-
Driessen, C.1
Lennon-Dumenil, A.M.2
Ploegh, H.L.3
-
59
-
-
0036177422
-
Specific role for cathepsin S in the generation of antigenic peptides in vivo
-
Pluger, E.B. et al. Specific role for cathepsin S in the generation of antigenic peptides in vivo. Eur. J. Immunol. 32, 467-476 (2002).
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 467-476
-
-
Pluger, E.B.1
-
60
-
-
0037087364
-
A Role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation
-
Hsieh, C.S., deRoos, P., Honey, K., Beers, C. & Rudensky, A.Y. A Role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J. Immunol. 168, 2618-2625 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 2618-2625
-
-
Hsieh, C.S.1
deRoos, P.2
Honey, K.3
Beers, C.4
Rudensky, A.Y.5
-
61
-
-
0037141021
-
+ T cell selection independently of its effect on invariant chain: A role in the generation of positively selecting peptide ligands
-
+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. J. Exp. Med. 195, 1349-1358 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1349-1358
-
-
Honey, K.1
Nakagawa, T.2
Peters, C.3
Rudensky, A.4
-
62
-
-
0032542285
-
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation
-
Manoury, B. et al. An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation. Nature 396, 695-699 (1998).
-
(1998)
Nature
, vol.396
, pp. 695-699
-
-
Manoury, B.1
-
63
-
-
0032435254
-
Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cystein endopeptidases
-
Chen, J.M., Rawlings, N.D., Stevens, R.A.E. & Barrett, A.J. Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cystein endopeptidases. FEBS Lett. 441, 461-465 (1998).
-
(1998)
FEBS Lett.
, vol.441
, pp. 461-465
-
-
Chen, J.M.1
Rawlings, N.D.2
Stevens, R.A.E.3
Barrett, A.J.4
-
64
-
-
1542705057
-
Roles for asparagine endopeptidase in class II MHC-restricted antigen processing
-
Watts, C. et al. Roles for asparagine endopeptidase in class II MHC-restricted antigen processing. Biochem. Soc. Symp. 70, 31-38 (2003).
-
(2003)
Biochem. Soc. Symp.
, vol.70
, pp. 31-38
-
-
Watts, C.1
-
65
-
-
0033696962
-
Control of antigen presentation by a single protease cleavage site
-
Antoniou, A.N., Blackwood, S.L., Mazzeo, D. & Watts, C. Control of antigen presentation by a single protease cleavage site. Immunity 12, 391-398 (2000).
-
(2000)
Immunity
, vol.12
, pp. 391-398
-
-
Antoniou, A.N.1
Blackwood, S.L.2
Mazzeo, D.3
Watts, C.4
-
66
-
-
0141626757
-
Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase
-
Loak, K. et al. Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase. Biol. Chem. 384, 1239-1246 (2003).
-
(2003)
Biol. Chem.
, vol.384
, pp. 1239-1246
-
-
Loak, K.1
-
67
-
-
0036167693
-
Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP
-
Manoury, B. et al. Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP. Nat. Immunol. 3, 169-174 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 169-174
-
-
Manoury, B.1
-
68
-
-
0034678450
-
Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
-
Krogsgaard, M. et al. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex. J. Exp. Med. 191, 1395-1412. (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1395-1412
-
-
Krogsgaard, M.1
-
69
-
-
1642340732
-
Lowering the affinity between antigen and the B cell receptor can enhance antigen presentation
-
Brooks, K. & Knight, A.M. Lowering the affinity between antigen and the B cell receptor can enhance antigen presentation. Eur. J. Immunol. 34, 837-843 (2004).
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 837-843
-
-
Brooks, K.1
Knight, A.M.2
-
70
-
-
0026343001
-
Reduction of disulfide bonds within lysosomes is a key step in antigen processing
-
Collins, D.S., Unanue, E.R. & Harding, C.V. Reduction of disulfide bonds within lysosomes is a key step in antigen processing. J. Immunol. 147, 4054-4059 (1991).
-
(1991)
J. Immunol.
, vol.147
, pp. 4054-4059
-
-
Collins, D.S.1
Unanue, E.R.2
Harding, C.V.3
-
71
-
-
0029445546
-
Antigen unfolding and disulfide reduction in antigen presenting cells
-
Jensen, P.E. Antigen unfolding and disulfide reduction in antigen presenting cells. Semin. Immunol. 7, 347-353 (1995).
-
(1995)
Semin. Immunol.
, vol.7
, pp. 347-353
-
-
Jensen, P.E.1
-
72
-
-
0034681122
-
Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a γ-interferon-inducible lysosomal thiol reductase (GILT)
-
Arunachalam, B., Phan, U.T., Geuze, H.J. & Cresswell, P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a γ-interferon-inducible lysosomal thiol reductase (GILT). Proc. Natl. Acad. Sci. USA 97, 745-50 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 745-750
-
-
Arunachalam, B.1
Phan, U.T.2
Geuze, H.J.3
Cresswell, P.4
-
73
-
-
0037141017
-
Absence of γ-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes
-
Haque, M.A. et al. Absence of γ-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes. J. Exp. Med. 195, 1267-1277 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1267-1277
-
-
Haque, M.A.1
-
74
-
-
0035834410
-
Defective antigen processing in GILT-free mice
-
Maric, M. et al. Defective antigen processing in GILT-free mice. Science 294, 1361-1365 (2001).
-
(2001)
Science
, vol.294
, pp. 1361-1365
-
-
Maric, M.1
-
75
-
-
0036721601
-
Role of disulfide bonds in regulating antigen processing and epitope selection
-
Li, P., Haque, M.A. & Blum, J.S. Role of disulfide bonds in regulating antigen processing and epitope selection. J. Immunol. 169, 2444-2450 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 2444-2450
-
-
Li, P.1
Haque, M.A.2
Blum, J.S.3
-
76
-
-
0036884519
-
Zwitterionic polysaccharides stimulate T cells by MHC class II-dependent interactions
-
Kalka-Moll, W.M. et al. Zwitterionic polysaccharides stimulate T cells by MHC class II-dependent interactions. J. Immunol. 169, 6149-6153 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 6149-6153
-
-
Kalka-Moll, W.M.1
-
77
-
-
2542507286
-
Polysaccharide processing and presentation by the MHCII pathway
-
Cobb, B.A., Wang, Q., Tzianabos, A.O. & Kasper, D.L. Polysaccharide processing and presentation by the MHCII pathway. Cell 117, 677-687 (2004).
-
(2004)
Cell
, vol.117
, pp. 677-687
-
-
Cobb, B.A.1
Wang, Q.2
Tzianabos, A.O.3
Kasper, D.L.4
-
78
-
-
0041876230
-
Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice
-
Shirahama-Noda, K. et al. Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. J. Biol. Chem. 278, 33194-33199 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33194-33199
-
-
Shirahama-Noda, K.1
-
79
-
-
0035933763
-
Cathepsin S regulates the Expression of cathepsin L and the turnover of γ-interferon-inducible lysosomal thiol reductase in B lymphocytes
-
Honey, K. et al. Cathepsin S regulates the Expression of cathepsin L and the turnover of γ-interferon-inducible lysosomal thiol reductase in B lymphocytes. J. Biol. Chem. 276, 22573-22578 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22573-22578
-
-
Honey, K.1
-
80
-
-
17844383711
-
The p41 isoform of invariant chain is a chaperone for cathepsin L
-
Lennon-Dumenil, A.M. et al. The p41 isoform of invariant chain is a chaperone for cathepsin L. EMBO J. 20, 4055-4064 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 4055-4064
-
-
Lennon-Dumenil, A.M.1
-
81
-
-
0036853166
-
Thymocyte expression of cathepsin L is essential for NKT cell development
-
Honey, K. et al. Thymocyte expression of cathepsin L is essential for NKT cell development. Nat. Immunol. 3, 1069-1074 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1069-1074
-
-
Honey, K.1
-
82
-
-
0039547996
-
Crystal structure of MHC class II-associated p41 li fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S
-
Guncar, G., Pungercic, G., Klemencic, I., Turk, V. & Turk, D. Crystal structure of MHC class II-associated p41 li fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S. EMBO J. 18, 793-803 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 793-803
-
-
Guncar, G.1
Pungercic, G.2
Klemencic, I.3
Turk, V.4
Turk, D.5
-
83
-
-
0027761288
-
Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney
-
Ogrinc, T., Dolenc, I., Ritonja, A. & Turk, V. Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney. FEBS Lett. 336, 555-559 (1993).
-
(1993)
FEBS Lett.
, vol.336
, pp. 555-559
-
-
Ogrinc, T.1
Dolenc, I.2
Ritonja, A.3
Turk, V.4
-
84
-
-
0037020835
-
Invariant chain controls the activity of extracellular cathepsin L
-
Fiebiger, E. et al. Invariant chain controls the activity of extracellular cathepsin L. J. Exp. Med. 196, 1263-1269 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1263-1269
-
-
Fiebiger, E.1
-
85
-
-
0037454948
-
Differential regulation of cathepsin S and cathepsin L in interferon-γ-treated macrophages
-
Beers, C., Honey, K., Fink, S., Forbush, K. & Rudensky, A. Differential regulation of cathepsin S and cathepsin L in interferon-γ-treated macrophages. J. Exp. Med. 197, 169-179 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 169-179
-
-
Beers, C.1
Honey, K.2
Fink, S.3
Forbush, K.4
Rudensky, A.5
-
86
-
-
0026729240
-
Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41
-
Peterson, M. & Miller, J. Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41. Nature 357, 596-598 (1992).
-
(1992)
Nature
, vol.357
, pp. 596-598
-
-
Peterson, M.1
Miller, J.2
-
87
-
-
0035896750
-
Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells
-
Fiebiger, E. et al. Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells. J. Exp. Med. 193, 881-892 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 881-892
-
-
Fiebiger, E.1
-
88
-
-
0037470438
-
Activation of lysosomal function during dendritic cell maturation
-
Trombetta, E.S., Ebersold, M., Garrett, W., Pypaert, M. & Mellman, I. Activation of lysosomal function during dendritic cell maturation. Science 299, 1400-1403 (2003).
-
(2003)
Science
, vol.299
, pp. 1400-1403
-
-
Trombetta, E.S.1
Ebersold, M.2
Garrett, W.3
Pypaert, M.4
Mellman, I.5
-
89
-
-
0141755165
-
Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo
-
Li, D.N., Matthews, S.P., Antoniou, A.N., Mazzeo, D. & Watts, C. Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo. J. Biol. Chem. 278, 38980-38990 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38980-38990
-
-
Li, D.N.1
Matthews, S.P.2
Antoniou, A.N.3
Mazzeo, D.4
Watts, C.5
-
90
-
-
0035494424
-
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
-
Kleijmeer, M. et al. Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J. Cell. Biol. 155, 53-63 (2001).
-
(2001)
J. Cell. Biol.
, vol.155
, pp. 53-63
-
-
Kleijmeer, M.1
-
91
-
-
0037194733
-
Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane
-
Chow, A., Toomre, D., Garrett, W. & Mellman, I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 418, 988-994 (2002).
-
(2002)
Nature
, vol.418
, pp. 988-994
-
-
Chow, A.1
Toomre, D.2
Garrett, W.3
Mellman, I.4
-
92
-
-
0030858138
-
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
-
Celia, M., Engering, A., Pinet, V., Pieters, J. & Lanzavecchia, A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782-787 (1997).
-
(1997)
Nature
, vol.388
, pp. 782-787
-
-
Celia, M.1
Engering, A.2
Pinet, V.3
Pieters, J.4
Lanzavecchia, A.5
-
93
-
-
0037039379
-
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
-
Steinman, R.M. & Nussenzweig, M.C. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 99, 351-358 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 351-358
-
-
Steinman, R.M.1
Nussenzweig, M.C.2
-
94
-
-
0038528584
-
Dendritic cells process and present antigens across a range of maturation states
-
Veeraswamy, R.K., Celia, M., Colonna, M. & Unanue, E.R. Dendritic cells process and present antigens across a range of maturation states. J. Immunol. 170, 5367-5372 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 5367-5372
-
-
Veeraswamy, R.K.1
Celia, M.2
Colonna, M.3
Unanue, E.R.4
-
95
-
-
1542373657
-
Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis
-
Wilson, N.S., El-Sukkari, D. & Villadangos, J.A. Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis. Blood 103, 2187-2195 (2004).
-
(2004)
Blood
, vol.103
, pp. 2187-2195
-
-
Wilson, N.S.1
El-Sukkari, D.2
Villadangos, J.A.3
-
96
-
-
0034697282
-
Transport of peptide-MHC class II complexes in developing dendritic cells
-
Turley, S.J. et al. Transport of peptide-MHC class II complexes in developing dendritic cells. Science 288, 522-527 (2000).
-
(2000)
Science
, vol.288
, pp. 522-527
-
-
Turley, S.J.1
-
97
-
-
0037194784
-
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport
-
Boes, M. et al. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature 418, 983-988 (2002).
-
(2002)
Nature
, vol.418
, pp. 983-988
-
-
Boes, M.1
-
98
-
-
0344153938
-
+ compartments in dendritic cells
-
+ compartments in dendritic cells. J. Immunol. 171, 5689-5696 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 5689-5696
-
-
Bertho, N.1
-
99
-
-
1042286458
-
Association of MHC class II-peptide complexes with plasma membrane lipid microdomains
-
Poloso, N.J. & Roche, P.A. Association of MHC class II-peptide complexes with plasma membrane lipid microdomains. Curr. Opin. Immunol. 16, 103-107 (2004).
-
(2004)
Curr. Opin. Immunol.
, vol.16
, pp. 103-107
-
-
Poloso, N.J.1
Roche, P.A.2
-
100
-
-
0036144745
-
Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes
-
Kropshofer, H. et al. Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes. Nat. Immunol. 3, 61-68 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 61-68
-
-
Kropshofer, H.1
-
101
-
-
0023853711
-
T cell recognition of fibrinogen. A determinant on the A α-chain does not require processing
-
Lee, P., Matsueda, G.R. & Allen, P.M. T cell recognition of fibrinogen. A determinant on the A α-chain does not require processing. J. Immunol. 140, 1063-1068 (1988).
-
(1988)
J. Immunol.
, vol.140
, pp. 1063-1068
-
-
Lee, P.1
Matsueda, G.R.2
Allen, P.M.3
-
102
-
-
0025939316
-
Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes
-
Davidson, H.W., Reid, P.A., Lanzavecchia, A. & Watts, C. Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes. Cell 67, 105-116 (1991).
-
(1991)
Cell
, vol.67
, pp. 105-116
-
-
Davidson, H.W.1
Reid, P.A.2
Lanzavecchia, A.3
Watts, C.4
-
103
-
-
0030451002
-
Distinct antigen MHC class II complexes generated by separate processing pathways
-
Lindner, R. & Unanue, E.R. Distinct antigen MHC class II complexes generated by separate processing pathways. EMBO J. 15, 6910-6920 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 6910-6920
-
-
Lindner, R.1
Unanue, E.R.2
-
104
-
-
0034161292
-
Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM
-
Villadangos, J.A., Driessen, C., Shi, G.-P., Chapman, H.A. & Ploegh, H.L. Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM. EMBO J. 19, 882-891 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 882-891
-
-
Villadangos, J.A.1
Driessen, C.2
Shi, G.-P.3
Chapman, H.A.4
Ploegh, H.L.5
-
105
-
-
0031030323
-
Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules
-
Nelson, C.A., Vidavsky, I., Viner, N.J., Gross, M.L. & Unanue, E.R. Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules. Proc. Natl. Acad. Sci. USA 94, 628-633 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 628-633
-
-
Nelson, C.A.1
Vidavsky, I.2
Viner, N.J.3
Gross, M.L.4
Unanue, E.R.5
-
106
-
-
0036839244
-
Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets
-
Lippolis, J.D. et al. Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets. J. Immunol. 169, 5089-5097 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 5089-5097
-
-
Lippolis, J.D.1
-
107
-
-
0030802693
-
T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage
-
Carson, R.T., Vignali, K.M., Woodland, D.L. & Vignali, D.A. T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage. Immunity 7, 387-399 (1997).
-
(1997)
Immunity
, vol.7
, pp. 387-399
-
-
Carson, R.T.1
Vignali, K.M.2
Woodland, D.L.3
Vignali, D.A.4
-
108
-
-
0141832121
-
MHC-guided processing: Binding of large antigen fragments
-
Sercarz, E.E. & Maverakis, E. MHC-guided processing: binding of large antigen fragments. Nat. Rev. Immunol. 3, 621-629 (2003).
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 621-629
-
-
Sercarz, E.E.1
Maverakis, E.2
-
109
-
-
0037290833
-
CD1-restricted antigen presentation: An oily matter
-
Joyce, S. & Van Kaer, L. CD1-restricted antigen presentation: an oily matter. Curr. Opin. Immunol. 15, 95-104 (2003).
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 95-104
-
-
Joyce, S.1
Van Kaer, L.2
-
110
-
-
2542448243
-
CD1: Antigen presentation and T cell function
-
Brigl, M. & Brenner, M.B. CD1: Antigen presentation and T cell function. Annu. Rev. Immunol. 22, 817-90 (2004).
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 817-890
-
-
Brigl, M.1
Brenner, M.B.2
-
111
-
-
0029029565
-
+ T lymphocytes
-
+ T lymphocytes. Science 268, 863-865 (1995).
-
(1995)
Science
, vol.268
, pp. 863-865
-
-
Bendelac, A.1
-
112
-
-
0035984523
-
Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains
-
Gadola, S.D. et al. Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains. Nat. Immunol. 3, 721-726 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 721-726
-
-
Gadola, S.D.1
-
113
-
-
0043198070
-
Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Å
-
Zajonc, D.M., Elsliger, M.A., Teyton, L. & Wilson, I.A. Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Å. Nat. Immunol. 4, 808-815 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 808-815
-
-
Zajonc, D.M.1
Elsliger, M.A.2
Teyton, L.3
Wilson, I.A.4
-
114
-
-
0036285648
-
Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells
-
Sugita, M. et al. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity 16, 697-706 (2002).
-
(2002)
Immunity
, vol.16
, pp. 697-706
-
-
Sugita, M.1
-
115
-
-
0142157012
-
α14i NKT cells
-
α14i NKT cells. J. Exp. Med. 198, 1133-1146 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1133-1146
-
-
Elewaut, D.1
-
116
-
-
0141958157
-
Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development
-
Cernadas, M. et al. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. J. Immunol. 171, 4149-4155 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 4149-4155
-
-
Cernadas, M.1
-
117
-
-
0035690582
-
CD1 trafficking: Invariant chain gives a new twist to the tale
-
Moody, D.B. & Porcelli, S.A. CD1 trafficking: invariant chain gives a new twist to the tale. Immunity 15, 861-865 (2001).
-
(2001)
Immunity
, vol.15
, pp. 861-865
-
-
Moody, D.B.1
Porcelli, S.A.2
-
118
-
-
0037007230
-
Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules
-
Kang, S.J. & Cresswell, P. Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 21, 1650-1660 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 1650-1660
-
-
Kang, S.J.1
Cresswell, P.2
-
119
-
-
0035690583
-
CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain
-
Jayawardena-Wolf, J., Benlagha, K., Chiu, Y.H., Mehr, R. & Bendelac, A. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 15, 897-908 (2001).
-
(2001)
Immunity
, vol.15
, pp. 897-908
-
-
Jayawardena-Wolf, J.1
Benlagha, K.2
Chiu, Y.H.3
Mehr, R.4
Bendelac, A.5
-
120
-
-
0036143535
-
Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d
-
Chiu, Y.H. et al. Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat. Immunol. 3, 55-60 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, pp. 55-60
-
-
Chiu, Y.H.1
-
121
-
-
18244391760
-
+ T cell selection and maturation by cathepsin S
-
+ T cell selection and maturation by cathepsin S. Immunity 15, 909-919 (2001).
-
(2001)
Immunity
, vol.15
, pp. 909-919
-
-
Riese, R.J.1
-
122
-
-
1142263116
-
Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells
-
Kang, S.J. & Cresswell, P. Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells. Nat. Immunol. 5, 175-181 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 175-181
-
-
Kang, S.J.1
Cresswell, P.2
-
123
-
-
9144256638
-
Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins
-
Zhou, D. et al. Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science 303, 523-527 (2004).
-
(2004)
Science
, vol.303
, pp. 523-527
-
-
Zhou, D.1
-
124
-
-
10744232076
-
Saposin C is required for lipid presentation by human CD1b
-
Winau, F. et al. Saposin C is required for lipid presentation by human CD1b. Nat. Immunol. 5, 169-174 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 169-174
-
-
Winau, F.1
-
125
-
-
0030016109
-
Proteolytic processing patterns of prosaposin in insect and mammalian cells
-
Leonova, T. et al. Proteolytic processing patterns of prosaposin in insect and mammalian cells. J. Biol. Chem. 271, 17312-17320 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17312-17320
-
-
Leonova, T.1
-
126
-
-
0029730641
-
Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP) precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor
-
Vielhaber, G., Hurwitz, R. & Sandhoff, K. Biosynthesis, processing, and targeting of sphingolipid activator protein (SAP) precursor in cultured human fibroblasts. Mannose 6-phosphate receptor-independent endocytosis of SAP precursor. J. Biol. Chem. 271, 32438-32446 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32438-32446
-
-
Vielhaber, G.1
Hurwitz, R.2
Sandhoff, K.3
-
127
-
-
0036644686
-
Promiscuous gene expression and central T-cell tolerance: More than meets the eye
-
Kyewski, B., Derbinski, J., Gotter, J. & Klein, L. Promiscuous gene expression and central T-cell tolerance: more than meets the eye. Trends Immunol. 23, 364-371 (2002).
-
(2002)
Trends Immunol.
, vol.23
, pp. 364-371
-
-
Kyewski, B.1
Derbinski, J.2
Gotter, J.3
Klein, L.4
-
128
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson, M.S. et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 10, 1395-1401 (2002).
-
(2002)
Science
, vol.10
, pp. 1395-1401
-
-
Anderson, M.S.1
-
129
-
-
0027421816
-
Structural analysis of proteolytic products of MHC class II-invariant chain complexes generated in vivo
-
Newcomb, J.R. & Cresswell, P. Structural analysis of proteolytic products of MHC class II-invariant chain complexes generated in vivo. J. Immunol. 151, 4153-4163 (1993).
-
(1993)
J. Immunol.
, vol.151
, pp. 4153-4163
-
-
Newcomb, J.R.1
Cresswell, P.2
-
130
-
-
0030458137
-
HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules
-
Denzin, L.K., Hammond, C. & Cresswell, P. HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J. Exp. Med. 184, 2153-2165 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 2153-2165
-
-
Denzin, L.K.1
Hammond, C.2
Cresswell, P.3
-
131
-
-
0029035307
-
Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
-
Simitsek, P.D., Campbell, D.G., Lanzavecchia, A., Fairweather, N. & Watts, C. Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J. Exp. Med. 181, 1957-1963 (1995).
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1957-1963
-
-
Simitsek, P.D.1
Campbell, D.G.2
Lanzavecchia, A.3
Fairweather, N.4
Watts, C.5
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