-
1
-
-
0028673279
-
Legumain: asparaginyl endopeptidase
-
Ishii S. Legumain: asparaginyl endopeptidase. Methods Enzymol. 244 (1994) 604-615
-
(1994)
Methods Enzymol.
, vol.244
, pp. 604-615
-
-
Ishii, S.1
-
2
-
-
0032435254
-
Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases
-
Chen J.M., Rawlings N.D., Stevens R.A., and Barrett A.J. Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases. FEBS Lett. 441 (1998) 361-365
-
(1998)
FEBS Lett.
, vol.441
, pp. 361-365
-
-
Chen, J.M.1
Rawlings, N.D.2
Stevens, R.A.3
Barrett, A.J.4
-
3
-
-
0027688051
-
Molecular characterization of a vacuolar processing enzyme related to a putative cysteine proteinase of Schistosoma mansoni
-
Hara-Nishimura I., Takeuchi Y., and Nishimura M. Molecular characterization of a vacuolar processing enzyme related to a putative cysteine proteinase of Schistosoma mansoni. Plant Cell 5 (1993) 1651-1659
-
(1993)
Plant Cell
, vol.5
, pp. 1651-1659
-
-
Hara-Nishimura, I.1
Takeuchi, Y.2
Nishimura, M.3
-
4
-
-
0042357049
-
Vacuolar processing enzymes are essential for proper processing of seed storage proteins in Arabidopsis thaliana
-
Shimada T., et al. Vacuolar processing enzymes are essential for proper processing of seed storage proteins in Arabidopsis thaliana. J. Biol. Chem. 278 (2003) 32292-32299
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 32292-32299
-
-
Shimada, T.1
-
5
-
-
3843128438
-
A plant vacuolar protease, VPE, mediates virus-induced hypersensitive cell death
-
Hatsugai N., Kuroyanagi M., Yamada K., Meshi T., Tsuda S., Kondo M., Nishimura M., and Hara-Nishimura I. A plant vacuolar protease, VPE, mediates virus-induced hypersensitive cell death. Science 305 (2004) 855-858
-
(2004)
Science
, vol.305
, pp. 855-858
-
-
Hatsugai, N.1
Kuroyanagi, M.2
Yamada, K.3
Meshi, T.4
Tsuda, S.5
Kondo, M.6
Nishimura, M.7
Hara-Nishimura, I.8
-
6
-
-
0030992979
-
Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase
-
Chen J.M., et al. Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase. J. Biol. Chem. 272 (1997) 8090-8098
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8090-8098
-
-
Chen, J.M.1
-
7
-
-
0041876230
-
Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice
-
Shirahama-Noda K., Yamamoto A., Sugihara K., Hashimoto N., Asano M., Nishimura M., and Hara-Nishimura I. Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice. J. Biol. Chem. 278 (2003) 33194-33199
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33194-33199
-
-
Shirahama-Noda, K.1
Yamamoto, A.2
Sugihara, K.3
Hashimoto, N.4
Asano, M.5
Nishimura, M.6
Hara-Nishimura, I.7
-
8
-
-
0032189364
-
Cloning and expression of mouse legumain, a lysosomal endopeptidase
-
Chen J.M., Dando P.M., Stevens R.A., Fortunato M., and Barrett A.J. Cloning and expression of mouse legumain, a lysosomal endopeptidase. Biochem. J. 335 Pt 1 (1998) 111-117
-
(1998)
Biochem. J.
, vol.335
, Issue.PART 1
, pp. 111-117
-
-
Chen, J.M.1
Dando, P.M.2
Stevens, R.A.3
Fortunato, M.4
Barrett, A.J.5
-
9
-
-
0036538799
-
Legumain from bovine kidney: its purification, molecular cloning, immunohistochemical localization and degradation of annexin II and vitamin D-binding protein
-
Yamane T., Takeuchi K., Yamamoto Y., Li Y.H., Fujiwara M., Nishi K., Takahashi S., and Ohkubo I. Legumain from bovine kidney: its purification, molecular cloning, immunohistochemical localization and degradation of annexin II and vitamin D-binding protein. Biochim. Biophys. Acta 1596 (2002) 108-120
-
(2002)
Biochim. Biophys. Acta
, vol.1596
, pp. 108-120
-
-
Yamane, T.1
Takeuchi, K.2
Yamamoto, Y.3
Li, Y.H.4
Fujiwara, M.5
Nishi, K.6
Takahashi, S.7
Ohkubo, I.8
-
10
-
-
26044442817
-
Macrophages direct tumour histology and clinical outcome in a colon cancer model
-
Oosterling S.J., et al. Macrophages direct tumour histology and clinical outcome in a colon cancer model. J. Pathol. 207 (2005) 147-155
-
(2005)
J. Pathol.
, vol.207
, pp. 147-155
-
-
Oosterling, S.J.1
-
11
-
-
0038243036
-
Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy
-
Liu C., Sun C., Huang H., Janda K., and Edgington T. Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy. Cancer Res. 63 (2003) 2957-2964
-
(2003)
Cancer Res.
, vol.63
, pp. 2957-2964
-
-
Liu, C.1
Sun, C.2
Huang, H.3
Janda, K.4
Edgington, T.5
-
12
-
-
16844367758
-
Legumain expression in relation to clinicopathologic and biological variables in colorectal cancer
-
Murthy R.V., Arbman G., Gao J., Roodman G.D., and Sun X.F. Legumain expression in relation to clinicopathologic and biological variables in colorectal cancer. Clin. Cancer Res. 11 (2005) 2293-2299
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 2293-2299
-
-
Murthy, R.V.1
Arbman, G.2
Gao, J.3
Roodman, G.D.4
Sun, X.F.5
-
13
-
-
33947400487
-
Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers
-
Moparthi S.B., Arbman G., Wallin A., Kayed H., Kleeff J., Zentgraf H., and Sun X.F. Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers. Int. J. Oncol. 30 (2007) 91-95
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 91-95
-
-
Moparthi, S.B.1
Arbman, G.2
Wallin, A.3
Kayed, H.4
Kleeff, J.5
Zentgraf, H.6
Sun, X.F.7
-
14
-
-
33746718151
-
Targeting tumor-associated macrophages as a novel strategy against breast cancer
-
Luo Y., et al. Targeting tumor-associated macrophages as a novel strategy against breast cancer. J. Clin. Invest. 116 (2006) 2132-2141
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2132-2141
-
-
Luo, Y.1
-
15
-
-
33746826203
-
Novel candidate genes in unstable areas of human atherosclerotic plaques
-
Papaspyridonos M., et al. Novel candidate genes in unstable areas of human atherosclerotic plaques. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 1837-1844
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 1837-1844
-
-
Papaspyridonos, M.1
-
16
-
-
0023896174
-
Three-dimensional network of cords: the main component of basement membranes
-
Inoue S., and Leblond C.P. Three-dimensional network of cords: the main component of basement membranes. Am. J. Anat. 181 (1988) 341-358
-
(1988)
Am. J. Anat.
, vol.181
, pp. 341-358
-
-
Inoue, S.1
Leblond, C.P.2
-
17
-
-
33748936323
-
Specific molecular targeting of renal injury in obstructive nephropathy
-
Chevalier R.L. Specific molecular targeting of renal injury in obstructive nephropathy. Kidney Int. 70 (2006) 1200-1201
-
(2006)
Kidney Int.
, vol.70
, pp. 1200-1201
-
-
Chevalier, R.L.1
-
18
-
-
0034053336
-
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
-
Koya D., et al. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. Faseb J. 14 (2000) 439-447
-
(2000)
Faseb J.
, vol.14
, pp. 439-447
-
-
Koya, D.1
-
19
-
-
0036796746
-
Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions
-
Sottile J., and Hocking D.C. Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. Mol. Biol. Cell 13 (2002) 3546-3559
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3546-3559
-
-
Sottile, J.1
Hocking, D.C.2
-
20
-
-
0034112260
-
Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats
-
Evans T., Deng D.X., Chen S., and Chakrabarti S. Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats. Diabetes 49 (2000) 662-666
-
(2000)
Diabetes
, vol.49
, pp. 662-666
-
-
Evans, T.1
Deng, D.X.2
Chen, S.3
Chakrabarti, S.4
-
21
-
-
0036087126
-
Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis
-
Yokoi H., et al. Role of connective tissue growth factor in fibronectin expression and tubulointerstitial fibrosis. Am. J. Physiol. Renal Physiol. 282 (2002) F933-F942
-
(2002)
Am. J. Physiol. Renal Physiol.
, vol.282
-
-
Yokoi, H.1
-
22
-
-
0035076282
-
Urinary tract obstruction
-
Klahr S. Urinary tract obstruction. Semin. Nephrol. 21 (2001) 133-145
-
(2001)
Semin. Nephrol.
, vol.21
, pp. 133-145
-
-
Klahr, S.1
-
23
-
-
0031943252
-
Differential effects of ACE and AT1 receptor inhibition on chemoattractant and adhesion molecule synthesis
-
Morrissey J.J., and Klahr S. Differential effects of ACE and AT1 receptor inhibition on chemoattractant and adhesion molecule synthesis. Am. J. Physiol. 274 (1998) F580-F586
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Morrissey, J.J.1
Klahr, S.2
-
24
-
-
0035030918
-
Contributions of angiotensin II and tumor necrosis factor-alpha to the development of renal fibrosis
-
Guo G., Morrissey J., McCracken R., Tolley T., Liapis H., and Klahr S. Contributions of angiotensin II and tumor necrosis factor-alpha to the development of renal fibrosis. Am. J. Physiol. Renal Physiol. 280 (2001) F777-F785
-
(2001)
Am. J. Physiol. Renal Physiol.
, vol.280
-
-
Guo, G.1
Morrissey, J.2
McCracken, R.3
Tolley, T.4
Liapis, H.5
Klahr, S.6
-
25
-
-
0028233556
-
Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney
-
Kaneto H., Morrissey J., McCracken R., Reyes A., and Klahr S. Enalapril reduces collagen type IV synthesis and expansion of the interstitium in the obstructed rat kidney. Kidney Int. 45 (1994) 1637-1647
-
(1994)
Kidney Int.
, vol.45
, pp. 1637-1647
-
-
Kaneto, H.1
Morrissey, J.2
McCracken, R.3
Reyes, A.4
Klahr, S.5
-
26
-
-
0024410550
-
The use of monoclonal antibodies to define levels of cystatin C in normal human serum
-
Ishiguro H., Ohkubo I., Mizokami M., Titani K., and Sasaki M. The use of monoclonal antibodies to define levels of cystatin C in normal human serum. Hybridoma 8 (1989) 303-313
-
(1989)
Hybridoma
, vol.8
, pp. 303-313
-
-
Ishiguro, H.1
Ohkubo, I.2
Mizokami, M.3
Titani, K.4
Sasaki, M.5
-
27
-
-
0021855104
-
Differences in domain structure between human fibronectins isolated from plasma and from culture supernatants of normal and transformed fibroblasts. Studies with domain-specific antibodies
-
Sekiguchi K., Siri A., Zardi L., and Hakomori S. Differences in domain structure between human fibronectins isolated from plasma and from culture supernatants of normal and transformed fibroblasts. Studies with domain-specific antibodies. J. Biol. Chem. 260 (1985) 5105-5114
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 5105-5114
-
-
Sekiguchi, K.1
Siri, A.2
Zardi, L.3
Hakomori, S.4
-
28
-
-
33750693942
-
Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice
-
Fu P., et al. Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice. J. Am. Soc. Nephrol. 17 (2006) 3105-3114
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 3105-3114
-
-
Fu, P.1
-
29
-
-
0037404251
-
Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells
-
Takaya K., Koya D., Isono M., Sugimoto T., Sugaya T., Kashiwagi A., and Haneda M. Involvement of ERK pathway in albumin-induced MCP-1 expression in mouse proximal tubular cells. Am. J. Physiol. Renal. Physiol. 284 (2003) F1037-F1045
-
(2003)
Am. J. Physiol. Renal. Physiol.
, vol.284
-
-
Takaya, K.1
Koya, D.2
Isono, M.3
Sugimoto, T.4
Sugaya, T.5
Kashiwagi, A.6
Haneda, M.7
-
30
-
-
33947387817
-
A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade
-
Okada H., et al. A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade. Am. J. Pathol. 169 (2006) 1577-1589
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 1577-1589
-
-
Okada, H.1
-
31
-
-
33645471300
-
Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis
-
Ostendorf T., et al. Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J. Am. Soc. Nephrol. 17 (2006) 1054-1062
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1054-1062
-
-
Ostendorf, T.1
-
32
-
-
0033516575
-
Inhibition of mammalian legumain by some cystatins is due to a novel second reactive site
-
Alvarez-Fernandez M., Barrett A.J., Gerhartz B., Dando P.M., Ni J., and Abrahamson M. Inhibition of mammalian legumain by some cystatins is due to a novel second reactive site. J. Biol. Chem. 274 (1999) 19195-19203
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19195-19203
-
-
Alvarez-Fernandez, M.1
Barrett, A.J.2
Gerhartz, B.3
Dando, P.M.4
Ni, J.5
Abrahamson, M.6
-
33
-
-
0022102304
-
Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene
-
Kornblihtt A.R., Umezawa K., Vibe-Pedersen K., and Baralle F.E. Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. Embo J. 4 (1985) 1755-1759
-
(1985)
Embo J.
, vol.4
, pp. 1755-1759
-
-
Kornblihtt, A.R.1
Umezawa, K.2
Vibe-Pedersen, K.3
Baralle, F.E.4
-
34
-
-
0041662269
-
A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake
-
East L., McCarthy A., Wienke D., Sturge J., Ashworth A., and Isacke C.M. A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake. EMBO Rep. 4 (2003) 710-716
-
(2003)
EMBO Rep.
, vol.4
, pp. 710-716
-
-
East, L.1
McCarthy, A.2
Wienke, D.3
Sturge, J.4
Ashworth, A.5
Isacke, C.M.6
-
35
-
-
12844269776
-
Fibronectin matrix turnover occurs through a caveolin-1-dependent process
-
Sottile J., and Chandler J. Fibronectin matrix turnover occurs through a caveolin-1-dependent process. Mol. Biol. Cell 16 (2005) 757-768
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 757-768
-
-
Sottile, J.1
Chandler, J.2
-
36
-
-
0033638127
-
Molecular basis of renal fibrosis
-
Eddy A.A. Molecular basis of renal fibrosis. Pediatr. Nephrol. 15 (2000) 290-301
-
(2000)
Pediatr. Nephrol.
, vol.15
, pp. 290-301
-
-
Eddy, A.A.1
-
37
-
-
33644638349
-
Renal fibrosis: new insights into the pathogenesis and therapeutics
-
Liu Y. Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int. 69 (2006) 213-217
-
(2006)
Kidney Int.
, vol.69
, pp. 213-217
-
-
Liu, Y.1
-
38
-
-
0032745254
-
Expression profile of extracellular matrix and its regulatory proteins during the process of interstitial fibrosis after anti-glomerular basement membrane antibody-induced glomerular sclerosis in Sprague-Dawley rats
-
Adhikary L.P., Yamamoto T., Isome M., Nakano Y., Kawasaki K., Yaoita E., and Kihara I. Expression profile of extracellular matrix and its regulatory proteins during the process of interstitial fibrosis after anti-glomerular basement membrane antibody-induced glomerular sclerosis in Sprague-Dawley rats. Pathol. Int. 49 (1999) 716-725
-
(1999)
Pathol. Int.
, vol.49
, pp. 716-725
-
-
Adhikary, L.P.1
Yamamoto, T.2
Isome, M.3
Nakano, Y.4
Kawasaki, K.5
Yaoita, E.6
Kihara, I.7
-
39
-
-
0032956765
-
Progressive renal disease: fibroblasts, extracellular matrix, and integrins
-
Norman J.T., and Fine L.G. Progressive renal disease: fibroblasts, extracellular matrix, and integrins. Exp. Nephrol. 7 (1999) 167-177
-
(1999)
Exp. Nephrol.
, vol.7
, pp. 167-177
-
-
Norman, J.T.1
Fine, L.G.2
-
40
-
-
0001201494
-
Experimental insights into the mechanisms of tubulo-interstitial scarring
-
El Nahas A., Harris K., and Anderson S. (Eds), Oxford University Press, Oxford
-
Jernigan S., and Eddy A.A. Experimental insights into the mechanisms of tubulo-interstitial scarring. In: El Nahas A., Harris K., and Anderson S. (Eds). Mechanisms and Clinical Management of Chronic Renal Failure (2000), Oxford University Press, Oxford 104-145
-
(2000)
Mechanisms and Clinical Management of Chronic Renal Failure
, pp. 104-145
-
-
Jernigan, S.1
Eddy, A.A.2
-
41
-
-
0034937132
-
Activation of progelatinase A by mammalian legumain, a recently discovered cysteine proteinase
-
Chen J.M., Fortunato M., Stevens R.A., and Barrett A.J. Activation of progelatinase A by mammalian legumain, a recently discovered cysteine proteinase. Biol. Chem. 382 (2001) 777-783
-
(2001)
Biol. Chem.
, vol.382
, pp. 777-783
-
-
Chen, J.M.1
Fortunato, M.2
Stevens, R.A.3
Barrett, A.J.4
|