Effects of urea on selectivity and protein-ligand interactions in multimodal cation exchange chromatography

Langmuir

Volumn 29, Issue 1, 2013, Pages 158-167

  Holstein, Melissa A ^a,c   Parimal, Siddharth ^a,c   McCallum, Scott A ^b,c   Cramer, Steven M ^a,c  

^a Rensselaer Polytechnic Institute   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION EXCHANGE CHROMATOGRAPHY; CHROMATOGRAPHIC SYSTEMS; FLUID-PHASE; IN-DEPTH ANALYSIS; ISOTOPICALLY ENRICHED; LIGAND BINDING; LIGAND INTERACTIONS; LIGAND-PROTEIN INTERACTION; MD SIMULATION; MOLECULAR DYNAMICS SIMULATIONS; MULTI-MODAL; NMR TITRATION; PROTEIN LIBRARY; PROTEIN RETENTION; PROTEIN-LIGAND INTERACTIONS; UBIQUITIN;

CHROMATOGRAPHY; LIGANDS; METABOLISM; MOLECULAR DYNAMICS; TITRATION; UREA;

PROTEINS;

LIGAND; PROTEIN; UBIQUITIN; UREA;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; ION EXCHANGE CHROMATOGRAPHY; METABOLISM; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING;

CHROMATOGRAPHY, ION EXCHANGE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEINS; UBIQUITIN; UREA;

EID: 84872106709     PISSN: 07437463     EISSN: 15205827     Source Type: Journal    
DOI: 10.1021/la302360b     Document Type: Article

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