Mobile phase modifier effects in multimodal cation exchange chromatography

Biotechnology and Bioengineering

Volumn 109, Issue 1, 2012, Pages 176-186

  Holstein, Melissa A ^a,b   Parimal, Siddharth ^a,b   McCallum, Scott A ^a,b   Cramer, Steven M ^a,b  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Adsorption; Mobile phase modifiers; Multimodal chromatography; Nuclear magnetic resonance; Protein library

Indexed keywords

BINDING BEHAVIORS; BOUND PROTEINS; CATION EXCHANGE CHROMATOGRAPHY; CHROMATOGRAPHIC RETENTION; CHROMATOGRAPHIC SYSTEMS; COMPETITIVE BINDING; DIVERSE PROTEINS; HYDROPHOBIC INTERACTIONS; ION EXCHANGE SYSTEMS; MOBILE PHASE MODIFIERS; MULTI-MODAL; MULTIMODAL SYSTEM; PROTEIN ADSORPTION; PROTEIN BINDING; PROTEIN LIBRARY; PROTEIN SEPARATIONS; RETENTION BEHAVIOR; SODIUM CAPRYLATE; STRUCTURAL BASIS; UBIQUITIN;

ADSORPTION; AMINO ACIDS; BINDING ENERGY; BIOCHEMISTRY; HYDROPHOBICITY; ION EXCHANGE; NUCLEAR MAGNETIC RESONANCE; PROTEINS;

CHROMATOGRAPHY;

ARGININE; GUANIDINE; ION EXCHANGE RESIN; OCTANOIC ACID; UBIQUITIN;

ADSORPTION; ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; HYDROPHOBICITY; ION EXCHANGE CHROMATOGRAPHY; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN BINDING; STATIC ELECTRICITY;

ADSORPTION; CATIONS; CHROMATOGRAPHY, ION EXCHANGE; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEINS;

EID: 81455158773     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23318     Document Type: Article

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