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Volumn 36, Issue 1, 2013, Pages 5-13

Brain renin-angiotensin system in the nexus of hypertension and aging

Author keywords

autonomic nervous system; brain; cardiovascular; metabolic; transgenic rats

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN[1-7]; LEPTIN; RENIN;

EID: 84872093629     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2012.161     Document Type: Review
Times cited : (47)

References (124)
  • 1
    • 77954684189 scopus 로고    scopus 로고
    • Aging of the autonomic nervous system and possible improvements in autonomic activity using somatic afferent stimulation
    • Hotta H, Uchida S. Aging of the autonomic nervous system and possible improvements in autonomic activity using somatic afferent stimulation. Geriatr Gerontol Int 2010; 10(Suppl 1): S127-S136.
    • (2010) Geriatr Gerontol Int , vol.10 , Issue.SUPPL. 1
    • Hotta, H.1    Uchida, S.2
  • 2
    • 3042691909 scopus 로고    scopus 로고
    • Invited review: Aging and the cardiovascular system
    • Ferrari AU, Radaelli A, Centola M. Invited review: aging and the cardiovascular system. J Appl Physiol 2003; 95: 2591-2597.
    • (2003) J Appl Physiol , vol.95 , pp. 2591-2597
    • Ferrari, A.U.1    Radaelli, A.2    Centola, M.3
  • 5
    • 49349107302 scopus 로고    scopus 로고
    • Renin-angiotensin system revisited
    • Fyhrquist F, Saijonmaa O. Renin-angiotensin system revisited. J Intern Med 2008; 264: 224-236.
    • (2008) J Intern Med , vol.264 , pp. 224-236
    • Fyhrquist, F.1    Saijonmaa, O.2
  • 8
    • 77954241805 scopus 로고    scopus 로고
    • Angiotensin receptor blockers for management of hypertension
    • Catanzaro DF, Frishman WH. Angiotensin receptor blockers for management of hypertension. South Med J 2010; 103: 669-673.
    • (2010) South Med J , vol.103 , pp. 669-673
    • Catanzaro, D.F.1    Frishman, W.H.2
  • 9
    • 42649115768 scopus 로고    scopus 로고
    • Recent advances in the angiotensinconverting enzyme 2-angiotensin 1-7)-Mas axis
    • Santos RA, Ferreira AJ, Simoes e Silva AC. Recent advances in the angiotensinconverting enzyme 2-angiotensin(1-7)-Mas axis. Exp Physiol 2008; 93: 519-527.
    • (2008) Exp Physiol , vol.93 , pp. 519-527
    • Santos, R.A.1    Ferreira, A.J.2    Simoes E Silva, A.C.3
  • 10
    • 0031601350 scopus 로고    scopus 로고
    • Angiotensin-1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system
    • Iyer SN, Ferrario CM, Chappell MC. Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension 1998; 31(1 Pt 2): 356-361.
    • (1998) Hypertension , vol.31 , Issue.1 PART 2 , pp. 356-361
    • Iyer, S.N.1    Ferrario, C.M.2    Chappell, M.C.3
  • 11
    • 0029129342 scopus 로고
    • Antihypertensive actions of angiotensin-1-7) in spontaneously hypertensive rats
    • Benter IF, Ferrario CM, Morris M, Diz DI. Antihypertensive actions of angiotensin-(1-7) in spontaneously hypertensive rats. Am J Physiol 1995; 269(1 Pt 2): H313-H319.
    • (1995) Am J Physiol , vol.269 , Issue.1 PART 2
    • Benter, I.F.1    Ferrario, C.M.2    Morris, M.3    Diz, D.I.4
  • 18
    • 84865577246 scopus 로고    scopus 로고
    • In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 Rats
    • Garcia-Espinosa MA, Shaltout HA, Gallagher PE, Chappell MC, Diz DI. In Vivo Expression of Angiotensin-(1-7) Lowers Blood Pressure and Improves Baroreflex Function in Transgenic (mRen2)27 Rats. J Cardiovasc Pharmacol 2012; 60: 150-157.
    • (2012) J Cardiovasc Pharmacol , vol.60 , pp. 150-157
    • Garcia-Espinosa, M.A.1    Shaltout, H.A.2    Gallagher, P.E.3    Chappell, M.C.4    Diz, D.I.5
  • 19
    • 84856088086 scopus 로고    scopus 로고
    • Angiotensin-(1-7) Deficiency and Baroreflex Impairment Precede the Antenatal Betamethasone Exposure-Induced Elevation in Blood Pressure
    • Shaltout HA, Rose JC, Chappell MC, Diz DI. Angiotensin-(1-7) Deficiency and Baroreflex Impairment Precede the Antenatal Betamethasone Exposure-Induced Elevation in Blood Pressure. Hypertension 2012; 59: 453-458.
    • (2012) Hypertension , vol.59 , pp. 453-458
    • Shaltout, H.A.1    Rose, J.C.2    Chappell, M.C.3    Diz, D.I.4
  • 21
    • 34249862899 scopus 로고    scopus 로고
    • Aging and the brain renin-angiotensin system: Insights from studies in transgenic rats
    • Diz DI, Kasper SO, Sakima A, Ferrario CM. Aging and the brain renin-angiotensin system: insights from studies in transgenic rats. Cleve Clin J Med 2007; 74(Suppl 1): S95-S98.
    • (2007) Cleve Clin J Med , vol.74 , Issue.SUPPL. 1
    • Diz, D.I.1    Kasper, S.O.2    Sakima, A.3    Ferrario, C.M.4
  • 23
    • 34249774906 scopus 로고    scopus 로고
    • Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio
    • Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I. Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. Endocrinology 2007; 148: 2453-2457.
    • (2007) Endocrinology , vol.148 , pp. 2453-2457
    • Wakahara, S.1    Konoshita, T.2    Mizuno, S.3    Motomura, M.4    Aoyama, C.5    Makino, Y.6    Kato, N.7    Koni, I.8    Miyamori, I.9
  • 24
    • 59849118931 scopus 로고    scopus 로고
    • Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension
    • Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in Circulatory and Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 in Fetal Programmed Hypertension. Hypertension 2009; 53: 404-408.
    • (2009) Hypertension , vol.53 , pp. 404-408
    • Shaltout, H.A.1    Figueroa, J.P.2    Rose, J.C.3    Diz, D.I.4    Chappell, M.C.5
  • 26
    • 81755177460 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system and glucose homeostasis
    • Luther JM, Brown NJ. The renin-angiotensin-aldosterone system and glucose homeostasis. Trends Pharmacol Sci 2011; 32: 734-739.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 734-739
    • Luther, J.M.1    Brown, N.J.2
  • 27
    • 2342540961 scopus 로고    scopus 로고
    • Impact of the renin-angiotensin system on lipid and carbohydrate metabolism
    • Strazzullo P, Galletti F. Impact of the renin-angiotensin system on lipid and carbohydrate metabolism. Curr Opin Nephrol Hypertens 2004; 13: 325-332.
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 325-332
    • Strazzullo, P.1    Galletti, F.2
  • 31
    • 78650919357 scopus 로고    scopus 로고
    • Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity
    • Yvan-Charvet L, Quignard-Boulange A. Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity. Kidney Int 2011; 79: 162-168.
    • (2011) Kidney Int , vol.79 , pp. 162-168
    • Yvan-Charvet, L.1    Quignard-Boulange, A.2
  • 35
    • 70350057468 scopus 로고    scopus 로고
    • Aliskiren reduces bodyweight gain, adiposity and plasma leptin during diet-induced obesity
    • Stucchi P, Cano V, Ruiz-Gayo M, Fernandez-Alfonso MS. Aliskiren reduces bodyweight gain, adiposity and plasma leptin during diet-induced obesity. Br J Pharmacol 2009; 158: 771-778.
    • (2009) Br J Pharmacol , vol.158 , pp. 771-778
    • Stucchi, P.1    Cano, V.2    Ruiz-Gayo, M.3    Fernandez-Alfonso, M.S.4
  • 36
    • 67649486849 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet
    • Weisinger RS, Stanley TK, Begg DP, Weisinger HS, Spark KJ, Jois M. Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet. Physiol Behav 2009; 98: 192-197.
    • (2009) Physiol Behav , vol.98 , pp. 192-197
    • Weisinger, R.S.1    Stanley, T.K.2    Begg, D.P.3    Weisinger, H.S.4    Spark, K.J.5    Jois, M.6
  • 37
    • 72649093929 scopus 로고    scopus 로고
    • Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat
    • Velkoska E, Warner FJ, Cole TJ, Smith I, Morris MJ. Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat. Nutr Metab Cardiovasc Dis 2010; 20: 49-55.
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 49-55
    • Velkoska, E.1    Warner, F.J.2    Cole, T.J.3    Smith, I.4    Morris, M.J.5
  • 38
    • 81555210904 scopus 로고    scopus 로고
    • Aliskiren prevents and ameliorates metabolic syndrome in fructose-fed rats
    • Chou CL, Lai YH, Lin TY, Lee TJ, Fang TC. Aliskiren prevents and ameliorates metabolic syndrome in fructose-fed rats. Arch Med Sci 2011; 7: 882-888.
    • (2011) Arch Med Sci , vol.7 , pp. 882-888
    • Chou, C.L.1    Lai, Y.H.2    Lin, T.Y.3    Lee, T.J.4    Fang, T.C.5
  • 43
    • 79959679349 scopus 로고    scopus 로고
    • Mechanistic and clinical aspects of renin-angiotensin-aldosterone system blockade in the prevention of diabetes mellitus and cardiovascular disease
    • Hershon KS. Mechanistic and clinical aspects of renin-angiotensin- aldosterone system blockade in the prevention of diabetes mellitus and cardiovascular disease. Endocr Pract 2011; 17: 430-440.
    • (2011) Endocr Pract , vol.17 , pp. 430-440
    • Hershon, K.S.1
  • 46
    • 0030667938 scopus 로고    scopus 로고
    • Angiotensin II affects basal, pulsatile, and glucose-stimulated insulin secretion in humans
    • Fliser D, Schaefer F, Schmid D, Veldhuis JD, Ritz E. Angiotensin II affects basal, pulsatile, and glucose-stimulated insulin secretion in humans. Hypertension 1997; 30: 1156-1161.
    • (1997) Hypertension , vol.30 , pp. 1156-1161
    • Fliser, D.1    Schaefer, F.2    Schmid, D.3    Veldhuis, J.D.4    Ritz, E.5
  • 47
    • 0027280155 scopus 로고
    • Angiotensin II enhances insulin sensitivity in healthy volunteers under euglycemic conditions
    • Fliser D, Arnold U, Kohl B, Hartung R, Ritz E. Angiotensin II enhances insulin sensitivity in healthy volunteers under euglycemic conditions. J Hypertens 1993; 11: 983-988.
    • (1993) J Hypertens , vol.11 , pp. 983-988
    • Fliser, D.1    Arnold, U.2    Kohl, B.3    Hartung, R.4    Ritz, E.5
  • 50
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288: 2981-2997.
    • (2002) JAMA , vol.288 , pp. 2981-2997
  • 51
    • 77950341044 scopus 로고    scopus 로고
    • Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas
    • Munoz MC, Giani JF, Dominici FP. Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas. Regul Pept 2010; 161: 1-7.
    • (2010) Regul Pept , vol.161 , pp. 1-7
    • Munoz, M.C.1    Giani, J.F.2    Dominici, F.P.3
  • 53
    • 62949127898 scopus 로고    scopus 로고
    • The sweeter side of ACE2: Physiological evidence for a role in diabetes
    • Bindom SM, Lazartigues E. The sweeter side of ACE2: Physiological evidence for a role in diabetes. Mol Cell Endocrinol 2009; 302: 193-202.
    • (2009) Mol Cell Endocrinol , vol.302 , pp. 193-202
    • Bindom, S.M.1    Lazartigues, E.2
  • 55
    • 77957558776 scopus 로고    scopus 로고
    • Ç ôConverting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice
    • Bindom SM, Hans CP, Xia H, Boulares AH, Lazartigues E, Angiotensin IG. Ç ôConverting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes 2010; 59: 2540-22548.
    • (2010) Diabetes , vol.59 , pp. 2540-22548
    • Bindom, S.M.1    Hans, C.P.2    Xia, H.3    Boulares, A.H.4    Lazartigues, E.5    Angiotensin, I.G.6
  • 56
    • 77951183011 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2: A new target for neurogenic hypertension
    • Feng Y, Xia H, Santos RA, Speth R, Lazartigues E. Angiotensin-converting enzyme 2: a new target for neurogenic hypertension. Exp Physiol 2010; 95: 601-606.
    • (2010) Exp Physiol , vol.95 , pp. 601-606
    • Feng, Y.1    Xia, H.2    Santos, R.A.3    Speth, R.4    Lazartigues, E.5
  • 57
    • 23244467912 scopus 로고    scopus 로고
    • Impaired heart rate baroreflex in older rats: Role of endogenous angiotensin-1-7) at the nucleus tractus solitarii
    • Sakima A, Averill DB, Gallagher PE, Kasper SO, Tommasi EN, Ferrario CM, Diz DI. Impaired heart rate baroreflex in older rats: role of endogenous angiotensin-(1-7) at the nucleus tractus solitarii. Hypertension 2005; 46: 333-340.
    • (2005) Hypertension , vol.46 , pp. 333-340
    • Sakima, A.1    Averill, D.B.2    Gallagher, P.E.3    Kasper, S.O.4    Tommasi, E.N.5    Ferrario, C.M.6    Diz, D.I.7
  • 58
    • 0027407197 scopus 로고
    • Age-related reduction of reflex bradycardia in conscious rats by catecholaminergic nucleus tractus solitarius lesions
    • Itoh H, Bunag RD. Age-related reduction of reflex bradycardia in conscious rats by catecholaminergic nucleus tractus solitarius lesions. Mech Ageing Dev 1993; 67: 47-63.
    • (1993) Mech Ageing Dev , vol.67 , pp. 47-63
    • Itoh, H.1    Bunag, R.D.2
  • 59
    • 74949084475 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function
    • Garcia-Espinosa MA, Shaltout HA, Olson J, Westwood BM, Robbins ME, Link K, Diz DI. Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function. Hypertension 2010; 55: 487-493.
    • (2010) Hypertension , vol.55 , pp. 487-493
    • Garcia-Espinosa, M.A.1    Shaltout, H.A.2    Olson, J.3    Westwood, B.M.4    Robbins, M.E.5    Link, K.6    Diz, D.I.7
  • 60
    • 84872087157 scopus 로고    scopus 로고
    • Correlation of the brain medullary metabolites N-acetyl aspartic acid and N-acetyl aspartyl glutamate with the age related decline in sensitivity for baroreflex control of heart rate in humans
    • (Abstract
    • Diz DI, Garcia-Espinosa MA, Shaltout HA, Olson J, Bourland JD, Groban L. Correlation of the brain medullary metabolites N-acetyl aspartic acid and N-acetyl aspartyl glutamate with the age related decline in sensitivity for baroreflex control of heart rate in humans. Hypertension 2011; 58: e116 (Abstract).
    • (2011) Hypertension , vol.58
    • Diz, D.I.1    Garcia-Espinosa, M.A.2    Shaltout, H.A.3    Olson, J.4    Bourland, J.D.5    Groban, L.6
  • 61
    • 33845692083 scopus 로고    scopus 로고
    • The role of vagal function in the risk for cardiovascular disease and mortality
    • Thayer JF, Lane RD. The role of vagal function in the risk for cardiovascular disease and mortality. Biol Psychol 2007; 74: 224-242.
    • (2007) Biol Psychol , vol.74 , pp. 224-242
    • Thayer, J.F.1    Lane, R.D.2
  • 63
    • 67449104698 scopus 로고    scopus 로고
    • Renin angiotensin system inhibition in the older person: A review
    • Mohamed MA, Weir MR. Renin angiotensin system inhibition in the older person: a review. Clin Geriatr Med 2009; 25: 245-257.
    • (2009) Clin Geriatr Med , vol.25 , pp. 245-257
    • Mohamed, M.A.1    Weir, M.R.2
  • 69
    • 79960810124 scopus 로고    scopus 로고
    • ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function
    • Xia H, Suda S, Bindom S, Feng Y, Gurley SB, Seth D, Navar LG, Lazartigues E. ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS One 2011; 6: e22682.
    • (2011) PLoS One , vol.6
    • Xia, H.1    Suda, S.2    Bindom, S.3    Feng, Y.4    Gurley, S.B.5    Seth, D.6    Navar, L.G.7    Lazartigues, E.8
  • 72
    • 0030905968 scopus 로고    scopus 로고
    • Ageing and the renin-angiotensin system
    • Anderson S. Ageing and the renin-angiotensin system. Nephrol Dial Transplant 1997; 12: 1093-1094.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 1093-1094
    • Anderson, S.1
  • 73
    • 46449122577 scopus 로고    scopus 로고
    • Dahl memorial lecture: The renin-angiotensin system and aging
    • Diz DI, Lewis K. Dahl memorial lecture: the renin-angiotensin system and aging. Hypertension 2008; 52: 37-43.
    • (2008) Hypertension , vol.52 , pp. 37-43
    • Diz, D.I.1    Lewis, K.2
  • 74
    • 0030824948 scopus 로고    scopus 로고
    • Role of angiotensin-1-7) in the modulation of the baroreflex in renovascular hypertensive rats
    • Britto RR, Santos RA, Fagundes-Moura CR, Khosla MC, Campagnole-Santos MJ. Role of angiotensin-(1-7) in the modulation of the baroreflex in renovascular hypertensive rats. Hypertension 1997; 30(3 Pt 2): 549-556.
    • (1997) Hypertension , vol.30 , Issue.3 PART 2 , pp. 549-556
    • Britto, R.R.1    Santos, R.A.2    Fagundes-Moura, C.R.3    Khosla, M.C.4    Campagnole-Santos, M.J.5
  • 76
    • 77954956655 scopus 로고    scopus 로고
    • Brain angiotensin peptides regulate sympathetic tone and blood pressure
    • Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens 2010; 28: 1599-1610.
    • (2010) J Hypertens , vol.28 , pp. 1599-1610
    • Dupont, A.G.1    Brouwers, S.2
  • 77
    • 0023899932 scopus 로고
    • Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii
    • Campagnole-Santos MJ, Diz DI, Ferrario CM. Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii. Hypertension 1988; 11(2 Pt 2): I167-I171.
    • (1988) Hypertension , vol.11 , Issue.2 PART 2
    • Campagnole-Santos, M.J.1    Diz, D.I.2    Ferrario, C.M.3
  • 78
    • 0022477010 scopus 로고
    • Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats
    • Casto R, Phillips MI. Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats. Am J Physiol 1986; 250(2 Pt 2): R193-R198.
    • (1986) Am J Physiol , vol.250 , Issue.2 PART 2
    • Casto, R.1    Phillips, M.I.2
  • 79
    • 0030004176 scopus 로고    scopus 로고
    • Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats
    • Oliveira DR, Santos RA, Santos GF, Khosla M, Campagnole-Santos MJ. Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats. Hypertension 1996; 27: 1284-1290.
    • (1996) Hypertension , vol.27 , pp. 1284-1290
    • Oliveira, D.R.1    Santos, R.A.2    Santos, G.F.3    Khosla, M.4    Campagnole-Santos, M.J.5
  • 80
    • 0033668722 scopus 로고    scopus 로고
    • Modulation of the baroreflex control of heart rate by angiotensin-1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats
    • Chaves GZ, Caligiorne SM, Santos RA, Khosla MC, Campagnole-Santos MJ. Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats. J Hypertens 2000; 18: 1841-1848.
    • (2000) J Hypertens , vol.18 , pp. 1841-1848
    • Chaves, G.Z.1    Caligiorne, S.M.2    Santos, R.A.3    Khosla, M.C.4    Campagnole-Santos, M.J.5
  • 82
    • 42649141198 scopus 로고    scopus 로고
    • Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
    • Diz DI, Garcia-Espinosa MA, Gegick S, Tommasi EN, Ferrario CM, Ann TE, Chappell MC, Gallagher PE. Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Exp Physiol 2008; 93: 694-700.
    • (2008) Exp Physiol , vol.93 , pp. 694-700
    • Diz, D.I.1    Garcia-Espinosa, M.A.2    Gegick, S.3    Tommasi, E.N.4    Ferrario, C.M.5    Ann, T.E.6    Chappell, M.C.7    Gallagher, P.E.8
  • 83
    • 0025733426 scopus 로고
    • Differential effects of aging on the heart rate and blood pressure influences of arterial baroreceptors in awake rats
    • Ferrari AU, Daffonchio A, Albergati F, Mancia G. Differential effects of aging on the heart rate and blood pressure influences of arterial baroreceptors in awake rats. J Hypertens 1991; 9: 615-621.
    • (1991) J Hypertens , vol.9 , pp. 615-621
    • Ferrari, A.U.1    Daffonchio, A.2    Albergati, F.3    Mancia, G.4
  • 85
    • 0026502928 scopus 로고
    • Transgenic rats carrying the mouse renin gene-morphological characterization of a low-renin hypertension model
    • Bachmann S, Peters J, Engler E, Ganten D, Mullins J. Transgenic rats carrying the mouse renin gene-morphological characterization of a low-renin hypertension model. Kidney Int 1992; 41: 24-36.
    • (1992) Kidney Int , vol.41 , pp. 24-36
    • Bachmann, S.1    Peters, J.2    Engler, E.3    Ganten, D.4    Mullins, J.5
  • 86
    • 82955188119 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats
    • Isa K, Arnold AC, Westwood BM, Chappell MC, Diz DI. Angiotensin- converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats. Hypertens Res 2011; 34: 1257-1262.
    • (2011) Hypertens Res , vol.34 , pp. 1257-1262
    • Isa, K.1    Arnold, A.C.2    Westwood, B.M.3    Chappell, M.C.4    Diz, D.I.5
  • 87
    • 84872089174 scopus 로고    scopus 로고
    • Chronic intracerebroventricular angiotensin-(1-7) infusion, but not AT1 receptor blockade, improves vagal components of the baroreflex function in hypertensive (mRen2)27 transgenic rats
    • (Abstract
    • Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Chronic intracerebroventricular angiotensin-(1-7) infusion, but not AT1 receptor blockade, improves vagal components of the baroreflex function in hypertensive (mRen2)27 transgenic rats. Hypertension 2011; 58: e96 (Abstract).
    • (2011) Hypertension , vol.58
    • Nautiyal, M.1    Shaltout, H.A.2    Chappell, M.C.3    Diz, D.I.4
  • 88
    • 0035726046 scopus 로고    scopus 로고
    • Differential role of kinases in brain stem of hypertensive and normotensive rats
    • Seyedabadi M, Goodchild AK, Pilowsky PM. Differential role of kinases in brain stem of hypertensive and normotensive rats. Hypertension 2001; 38: 1087-1092.
    • (2001) Hypertension , vol.38 , pp. 1087-1092
    • Seyedabadi, M.1    Goodchild, A.K.2    Pilowsky, P.M.3
  • 89
    • 80053944510 scopus 로고    scopus 로고
    • The functional role of PI3K in maintenance of blood pressure and baroreflex suppression in (mRen2)27 and mRen2. Lewis rat
    • Logan EM, Aileru AA, Shaltout HA, Averill DB, Diz DI. The functional role of PI3K in maintenance of blood pressure and baroreflex suppression in (mRen2)27 and mRen2. Lewis rat. J Cardiovasc Pharmacol 2011; 58: 367-373.
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 367-373
    • Logan, E.M.1    Aileru, A.A.2    Shaltout, H.A.3    Averill, D.B.4    Diz, D.I.5
  • 93
    • 29244447183 scopus 로고    scopus 로고
    • Low glial angiotensinogen is not associated with deficits in angiotensin peptides in neuronal pathways in transgenic ASrAogen rats
    • (Abstract
    • Vinsant S, Chappell MC, Ferrario CM, Ganten D, Diz DI. Low glial angiotensinogen is not associated with deficits in angiotensin peptides in neuronal pathways in transgenic ASrAogen rats. FASEB J 2005; 19: A1188 (Abstract).
    • (2005) FASEB J , vol.19
    • Vinsant, S.1    Chappell, M.C.2    Ferrario, C.M.3    Ganten, D.4    Diz, D.I.5
  • 94
    • 0035090067 scopus 로고    scopus 로고
    • Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen
    • Baltatu O, Janssen BJ, Bricca G, Plehm R, Monti J, Ganten D, Bader M. Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen. Hypertension 2001; 37(2 Part 2): 408-413.
    • (2001) Hypertension , vol.37 , Issue.2 PART 2 , pp. 408-413
    • Baltatu, O.1    Janssen, B.J.2    Bricca, G.3    Plehm, R.4    Monti, J.5    Ganten, D.6    Bader, M.7
  • 97
    • 42349089333 scopus 로고    scopus 로고
    • Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen
    • Arnold AC, Sakima A, Ganten D, Ferrario CM, Diz DI. Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen. Hypertension 2008; 51: 1326-1331.
    • (2008) Hypertension , vol.51 , pp. 1326-1331
    • Arnold, A.C.1    Sakima, A.2    Ganten, D.3    Ferrario, C.M.4    Diz, D.I.5
  • 98
    • 15244340172 scopus 로고    scopus 로고
    • Differential modulation of baroreflex control of heart rate by neuron-vs. glia-derived angiotensin II
    • Sakai K, Chapleau MW, Morimoto S, Cassell MD, Sigmund CD. Differential modulation of baroreflex control of heart rate by neuron-vs. glia-derived angiotensin II. Physiol Genomics 2004; 20: 66-72.
    • (2004) Physiol Genomics , vol.20 , pp. 66-72
    • Sakai, K.1    Chapleau, M.W.2    Morimoto, S.3    Cassell, M.D.4    Sigmund, C.D.5
  • 101
    • 78650456535 scopus 로고    scopus 로고
    • Angiotensin II blockade: A strategy to slow ageing by protecting mitochondria?
    • de Cavanagh EM, Inserra F, Ferder L. Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria? Cardiovasc Res 2011; 89: 31-40.
    • (2011) Cardiovasc Res , vol.89 , pp. 31-40
    • De Cavanagh, E.M.1    Inserra, F.2    Ferder, L.3
  • 104
    • 77952546615 scopus 로고    scopus 로고
    • The brain RAS and Alzheimer's disease
    • Wright JW, Harding JW. The brain RAS and Alzheimer's disease. Exp Neurol 2010; 223: 326-333.
    • (2010) Exp Neurol , vol.223 , pp. 326-333
    • Wright, J.W.1    Harding, J.W.2
  • 106
    • 0036791462 scopus 로고    scopus 로고
    • Leptin and insulin action in the central nervous system
    • Porte Jr. D, Baskin DG, Schwartz MW. Leptin and insulin action in the central nervous system. Nutr Rev 2002; 60(10 Pt 2): S20-S29.
    • (2002) Nutr Rev , vol.60 , Issue.10 PART 2
    • Porte Jr., D.1    Baskin, D.G.2    Schwartz, M.W.3
  • 107
    • 33847364813 scopus 로고    scopus 로고
    • Rats with low brain angiotensinogen do not exhibit insulin resistance during early aging
    • Kasper SO, Ferrario CM, Ganten D, Diz DI. Rats with low brain angiotensinogen do not exhibit insulin resistance during early aging. Endocrine 2006; 30: 167-174.
    • (2006) Endocrine , vol.30 , pp. 167-174
    • Kasper, S.O.1    Ferrario, C.M.2    Ganten, D.3    Diz, D.I.4
  • 109
    • 36549059075 scopus 로고    scopus 로고
    • Inhibition of the protein tyrosine phosphatase PTP1B: Potential therapy for obesity, insulin resistance and type-2 diabetes mellitus
    • Koren S, Fantus IG. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus. Best Pract Res Clin Endocrinol Metab 2007; 21: 621-640.
    • (2007) Best Pract Res Clin Endocrinol Metab , vol.21 , pp. 621-640
    • Koren, S.1    Fantus, I.G.2
  • 112
    • 20444367066 scopus 로고    scopus 로고
    • Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN
    • Kasper SO, Ferrario CM, Ganten D, Diz DI. Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN. Neurotox Res 2004; 6: 259-265.
    • (2004) Neurotox Res , vol.6 , pp. 259-265
    • Kasper, S.O.1    Ferrario, C.M.2    Ganten, D.3    Diz, D.I.4
  • 113
    • 0036563174 scopus 로고    scopus 로고
    • Differential effects of angiotensin II and angiotensin-1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen
    • Couto AS, Baltatu O, Santos RA, Ganten D, Bader M, Campagnole-Santos MJ. Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen. J Hypertens 2002; 20: 919-925.
    • (2002) J Hypertens , vol.20 , pp. 919-925
    • Couto, A.S.1    Baltatu, O.2    Santos, R.A.3    Ganten, D.4    Bader, M.5    Campagnole-Santos, M.J.6
  • 114
    • 70449706328 scopus 로고    scopus 로고
    • Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus
    • Arnold AC, Shaltout HA, Gallagher PE, Diz DI. Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus. Hypertension 2009; 54: 1001-1008.
    • (2009) Hypertension , vol.54 , pp. 1001-1008
    • Arnold, A.C.1    Shaltout, H.A.2    Gallagher, P.E.3    Diz, D.I.4
  • 115
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
    • Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 2007; 292: C82-C97.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Mehta, P.K.1    Griendling, K.K.2
  • 116
  • 117
    • 59849116907 scopus 로고    scopus 로고
    • Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney
    • Mark AL, Agassandian K, Morgan DA, Liu X, Cassell MD, Rahmouni K. Leptin signaling in the nucleus tractus solitarii increases sympathetic nerve activity to the kidney. Hypertension 2009; 53: 375-380.
    • (2009) Hypertension , vol.53 , pp. 375-380
    • Mark, A.L.1    Agassandian, K.2    Morgan, D.A.3    Liu, X.4    Cassell, M.D.5    Rahmouni, K.6
  • 118
    • 0036269954 scopus 로고    scopus 로고
    • Angiotensin II increases leptin secretion by 3T3-L1 and human adipocytes via a prostaglandinindependent mechanism
    • Kim S, Whelan J, Claycombe K, Reath DB, Moustaid-Moussa N. Angiotensin II increases leptin secretion by 3T3-L1 and human adipocytes via a prostaglandinindependent mechanism. J Nutr 2002; 132: 1135-1140.
    • (2002) J Nutr , vol.132 , pp. 1135-1140
    • Kim, S.1    Whelan, J.2    Claycombe, K.3    Reath, D.B.4    Moustaid-Moussa, N.5
  • 119
    • 0346458801 scopus 로고    scopus 로고
    • Differential effects of local versus systemic angiotensin II in the regulation of leptin release from adipocytes
    • Cassis LA, English VL, Bharadwaj K, Boustany CM. Differential effects of local versus systemic angiotensin II in the regulation of leptin release from adipocytes. Endocrinology 2004; 145: 169-174.
    • (2004) Endocrinology , vol.145 , pp. 169-174
    • Cassis, L.A.1    English, V.L.2    Bharadwaj, K.3    Boustany, C.M.4
  • 121
    • 64949128269 scopus 로고    scopus 로고
    • Distinct metabolic effects of different classes of antihypertensive drugs
    • Koh KK. Distinct metabolic effects of different classes of antihypertensive drugs. Hypertension 2009; 53: e26.
    • (2009) Hypertension , vol.53
    • Koh, K.K.1
  • 122
    • 20444479426 scopus 로고    scopus 로고
    • Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients
    • Fogari R, Derosa G, Zoppi A, Rinaldi A, Lazzari P, Fogari E, Mugellini A, Preti P. Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. Hypertens Res 2005; 28: 209-214.
    • (2005) Hypertens Res , vol.28 , pp. 209-214
    • Fogari, R.1    Derosa, G.2    Zoppi, A.3    Rinaldi, A.4    Lazzari, P.5    Fogari, E.6    Mugellini, A.7    Preti, P.8
  • 124
    • 79954414794 scopus 로고    scopus 로고
    • Endogenous leptin within the solitary tract nucleus contributes to age-related baroreflex suppression in older anesthetized sprague-dawley rats
    • Abstract
    • Arnold AC, Diz DI. Endogenous leptin within the solitary tract nucleus contributes to age-related baroreflex suppression in older anesthetized sprague-dawley rats Hypertension 2010; 56: e72 (Abstract).
    • (2010) Hypertension , vol.56
    • Arnold, A.C.1    Diz, D.I.2


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