-
2
-
-
34548414599
-
Protective effect of long-term angiotensin II inhibition
-
DOI 10.1152/ajpheart.00393.2007
-
Basso N, Cini Pietrelli A R, Ferder L, Terragno NA, Inserra F. Protective effect of long-term angiotensin II inhibition. Am J Physiol Heart Circ Physiol 293: H1351-H1358, 2007. (Pubitemid 47367173)
-
(2007)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.293
, Issue.3
-
-
Basso, N.1
Cini, R.2
Pietrelli, A.3
Ferder, L.4
Terragno, N.A.5
Inserra, F.6
-
3
-
-
65349128571
-
Disruption of the Ang II type 1 receptor promotes longevity in mice
-
Benigni A, Corna D, Zoja C, Sonzogni A, Latini R, Salio M, Conti S, Rottoli D, Longaretti L, Cassis P, Morigi M, Coffman TM, Remuzzi G. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 119: 524-530, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 524-530
-
-
Benigni, A.1
Corna, D.2
Zoja, C.3
Sonzogni, A.4
Latini, R.5
Salio, M.6
Conti, S.7
Rottoli, D.8
Longaretti, L.9
Cassis, P.10
Morigi, M.11
Coffman, T.M.12
Remuzzi, G.13
-
4
-
-
34548146108
-
Effect of aging, MnSOD deficiency, and genetic background on endothelial function: Evidence for MnSOD haploinsufficiency
-
DOI 10.1161/ATVBAHA.107.146852, PII 0004360520070900000012
-
Brown KA, Didion SP, Andresen JJ, Faraci FM. Effect of aging, MnSOD deficiency, and genetic background on endothelial function: evidence for MnSOD haploinsufficiency. Arterioscler Thromb Vasc Biol 27: 1941-1946, 2007. (Pubitemid 47312302)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.9
, pp. 1941-1946
-
-
Brown, K.A.1
Didion, S.P.2
Andresen, J.J.3
Faraci, F.M.4
-
5
-
-
54449093276
-
The role of oxidative stress and NADPH oxidase in cerebrovascular disease
-
Chrissobolis S, Faraci FM. The role of oxidative stress and NADPH oxidase in cerebrovascular disease. Trends Mol Med 14: 495-502, 2008.
-
(2008)
Trends Mol Med
, vol.14
, pp. 495-502
-
-
Chrissobolis, S.1
Faraci, F.M.2
-
6
-
-
65249129115
-
Ca channels, myogenic tone, and vasodilator responses in middle cerebral arteries and parenchymal arterioles: Effec of ischemia and reperfusion
-
Ca channels, myogenic tone, and vasodilator responses in middle cerebral arteries and parenchymal arterioles: effec of ischemia and reperfusion. Stroke 40: 1451-1457-1502, 2009.
-
(2009)
Stroke
, vol.40
-
-
Cipolla, M.J.1
Smith, J.2
Kohlmeyer, M.M.3
Godfrey, J.A.4
-
7
-
-
33751094316
-
Heterozygous CuZn superoxide dismutase deficiency produces a vascular phenotype with aging
-
DOI 10.1161/01.HYP.0000247302.20559.3a, PII 0000426820061200000015
-
Didion SP, Kinzenbaw DA, Schrader LI, Faraci FM. Heterozygous CuZn superoxide dismutase deficiency produces a vascular phenotype with aging. Hypertension 48: 1072-1079, 2006. (Pubitemid 44772710)
-
(2006)
Hypertension
, vol.48
, Issue.6
, pp. 1072-1079
-
-
Didion, S.P.1
Kinzenbaw, D.A.2
Schrader, L.I.3
Faraci, F.M.4
-
8
-
-
0035048905
-
Tissue angiotensin and pathobiology of vascular disease a unifying hypothesis
-
Dzau VJ. Tissue angiotensin and pathophysiology of vascular disease. A unifying hypothesis. Hypertension 37: 1047-1052, 2001. (Pubitemid 32304002)
-
(2001)
Hypertension
, vol.37
, Issue.4
, pp. 1047-1052
-
-
Dzau, V.J.1
-
9
-
-
0027057558
-
Regulation of the cerebral circulation by endothelium
-
Faraci FM. Regulation of the cerebral circulation by endothelium. Pharmacol Ther 56: 1-22, 1992. (Pubitemid 23070495)
-
(1992)
Pharmacology and Therapeutics
, vol.56
, Issue.1
, pp. 1-22
-
-
Faraci, F.M.1
-
10
-
-
0345642933
-
Cerebral circulation during aging
-
edited by Phillis JW. Boca Raton, FL: CRC
-
Faraci FM. Cerebral circulation during aging. In: The Regulation of Cerebral Blood Flow, edited by Phillis JW. Boca Raton, FL: CRC, 1993, p. 341-352.
-
(1993)
The Regulation of Cerebral Blood Flow
, pp. 341-352
-
-
Faraci, F.M.1
-
11
-
-
3943073829
-
Vascular protection: Superoxide dismutase isoforms in the vessel wall
-
DOI 10.1161/01.ATV.0000133604.20182.cf
-
Faraci FM, Didion SP. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler Thromb Vasc Biol 24: 1367-1373, 2004. (Pubitemid 39050427)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.8
, pp. 1367-1373
-
-
Faraci, F.M.1
Didion, S.P.2
-
12
-
-
0025097985
-
Regulation of large cerebral arteries and cerebral microsvascular pressure
-
Faraci FM, Heistad DD. Regulation of large cerebral arteries and cerebral microvascular pressure. Circ Res 66: 8-17, 1990. (Pubitemid 20033921)
-
(1990)
Circulation Research
, vol.66
, Issue.1
, pp. 8-17
-
-
Faraci, F.M.1
Heistad, D.D.2
-
13
-
-
0031893415
-
Regulation of the cerebral circulation: Role of endothelium and potassium channels
-
Faraci FM, Heistad DD. Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol Rev 78: 53-97, 1998. (Pubitemid 28070975)
-
(1998)
Physiological Reviews
, vol.78
, Issue.1
, pp. 53-97
-
-
Faraci, F.M.1
Heistad, D.D.2
-
14
-
-
33645849538
-
Cerebral vascular effects of angiotensin II: New insights from genetic models
-
Faraci FM, Lamping KG, Modrick ML, Ryan MJ, Sigmund CD, Didion SP. Cerebral vascular effects of angiotensin II: new insights from genetic models. J Cereb Blood Flow Metab 26: 449-455, 2006.
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 449-455
-
-
Faraci, F.M.1
Lamping, K.G.2
Modrick, M.L.3
Ryan, M.J.4
Sigmund, C.D.5
Didion, S.P.6
-
15
-
-
33744946795
-
Selective cerebral vascular dysfunction in Mn-SOD-deficient mice
-
DOI 10.1152/japplphysiol.00939.2005
-
Faraci FM, Modrick ML, Lynch CM, Didion LA, Fegan PE, Didion SP. Selective cerebral vascular dysfunction in Mn-SOD-deficient mice. J Appl Physiol 100: 2089-2093, 2006. (Pubitemid 43845886)
-
(2006)
Journal of Applied Physiology
, vol.100
, Issue.6
, pp. 2089-2093
-
-
Faraci, F.M.1
Modrick, M.L.2
Lynch, C.M.3
Didion, L.A.4
Fegan, P.E.5
Didion, S.P.6
-
16
-
-
28844473846
-
Radical medicine: Treating ageing to cure disease
-
DOI 10.1038/nrm1763
-
Finkel T. Radical medicine: treating ageing to cure disease. Nat Rev Mol Cell Biol 6: 971-976, 2005. (Pubitemid 41778716)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.12
, pp. 971-976
-
-
Finkel, T.1
-
17
-
-
0027136046
-
Physiology of cardiovascular aging
-
Folkow B, Svanborg A. Physiology of cardiovascular aging. Physiol Rev 73: 725-764, 1993. (Pubitemid 24004651)
-
(1993)
Physiological Reviews
, vol.73
, Issue.4
, pp. 725-764
-
-
Folkow, B.1
Svanborg, A.2
-
19
-
-
7644223380
-
Risk factors for vascular dementia and Alzheimer disease
-
DOI 10.1161/01.STR.0000143318.70292.47
-
Gorelick PB. Risk factors for vascular dementia and Alzheimer's disease. Stroke 35, Suppl 1: 2620-2622, 2004. (Pubitemid 39458352)
-
(2004)
Stroke
, vol.35
, Issue.11 SUPPL. 1
, pp. 2620-2622
-
-
Gorelick, P.B.1
-
20
-
-
0025336725
-
Effects of aging on mechanics and composition of cerebral arterioles in rats
-
Hajdu MA, Heistad DD, Siems JW, Baumbach GL. Effects of aging on mechanics and composition of cerebral arterioles in rats. Circ Res 66: 1747-1754, 1990. (Pubitemid 20178723)
-
(1990)
Circulation Research
, vol.66
, Issue.6
, pp. 1747-1754
-
-
Hajdu, M.A.1
Heistad, D.D.2
Siems, J.E.3
Baumbach, G.L.4
-
21
-
-
0025289830
-
Effect of aging on endothelium-dependent vascular relaxation of isolated human basilar artery to thrombin and bradykinin
-
Hatake K, Kakishita E, Wakabayashi I, Sakiyama N, Hishida S. Effect of aging on endothelium-dependent vascular relaxation of isolated human basilar artery to thrombin and bradykinin. Stroke 21: 1039-1043, 1990. (Pubitemid 20218168)
-
(1990)
Stroke
, vol.21
, Issue.7
, pp. 1039-1043
-
-
Hatake, K.1
Kakishita, E.2
Wakabayashi, I.3
Sakiyama, N.4
Hishida, S.5
-
22
-
-
0031686286
-
Genetic deletion and overexpression of angiotensin II receptors
-
DOI 10.1007/s001090050277
-
Hein L. Genetic deletion and overexpression of angiotensin II receptors. J Mol Med 76: 756-763. 1998. (Pubitemid 28475170)
-
(1998)
Journal of Molecular Medicine
, vol.76
, Issue.11
, pp. 756-763
-
-
Hein, L.1
-
23
-
-
44349096287
-
Hypertension and cerebrovascular dysfunction
-
Iadecola C, Davisson RL. Hypertension and cerebrovascular dysfunction. Cell Metab 7: 476-484, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 476-484
-
-
Iadecola, C.1
Davisson, R.L.2
-
24
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
DOI 10.1038/nrd1718
-
Jagtap P, Szabo C. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4: 421-440, 2005. (Pubitemid 40704125)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.5
, pp. 421-440
-
-
Jagtap, P.1
Szabo, C.2
-
25
-
-
33646684516
-
New insights into structure and function of mitochondria and their role in aging and disease
-
DOI 10.1089/ars.2006.8.417
-
Lenaz G, Baracca A, Fato R, Genova ML, Solaini G. New insights into structure and function of mitochondria and their role in aging and disease. Antioxid Redox Signal 8: 417-437, 2006. (Pubitemid 43741313)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.3-4
, pp. 417-437
-
-
Lenaz, G.1
Baracca, A.2
Fato, R.3
Genova, M.L.4
Solaini, G.5
-
27
-
-
33645082252
-
Peroxynitrite diminishes myogenic activity and is associated with decreased vascular smooth muscle F-actin in rat posterior cerebral arteries
-
DOI 10.1161/01.STR.0000204043.18592.0d, PII 0000767020060300000038
-
Maneen MJ, Hannah R, Vitullo L, DeLance N, Cipolla MJ. Peroxynitrite diminishes myogenic tone and is associated with decreased vascular smooth muscle F-actin in rat posterior cerebral arteries. Stroke 37: 894-899, 2006. (Pubitemid 43731928)
-
(2006)
Stroke
, vol.37
, Issue.3
, pp. 894-899
-
-
Maneen, M.J.1
Hannah, R.2
Vitullo, L.3
Delance, N.4
Cipolla, M.J.5
-
28
-
-
0028957303
-
Age-related changes in vascular responses: A review
-
Marin J. Age-related changes in vascular responses: a review. Mech Ageing Dev 79: 71-114, 1995.
-
(1995)
Mech Ageing Dev
, vol.79
, pp. 71-114
-
-
Marin, J.1
-
29
-
-
46449096453
-
Age-related alterations in reactivity of cerebral arterioles: Role of oxidative stress
-
Mayhan WG, Arrick DM, Sharpe GM, Sun H. Age-related alterations in reactivity of cerebral arterioles: role of oxidative stress. Microcirculation 15: 225-236, 2008.
-
(2008)
Microcirculation
, vol.15
, pp. 225-236
-
-
Mayhan, W.G.1
Arrick, D.M.2
Sharpe, G.M.3
Sun, H.4
-
30
-
-
33846362954
-
Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
-
DOI 10.1152/ajpcell.00287.2006
-
Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292: C82-C97, 2007. (Pubitemid 46127306)
-
(2007)
American Journal of Physiology - Cell Physiology
, vol.292
, Issue.1
-
-
Mehta, P.K.1
Griendling, K.K.2
-
31
-
-
0033586684
-
Intracranial arteries of human fetuses are more resistant to hypercholesterolemia-induced fatty streak formation than extracranial arteries
-
Napoli C, Witztum JL, de Nigris F, Palumbo G, D'Armiento FP, Palinski W. Intracranial arteries of human fetuses are more resistant to hypercholesterolemia-induced fatty streak formation than extracranial arteries. Circulation 99: 2003-2010, 1999. (Pubitemid 29183898)
-
(1999)
Circulation
, vol.99
, Issue.15
, pp. 2003-2010
-
-
Napoli, C.1
Witztum, J.L.2
De Nigris, F.3
Palumbo, G.4
D'Armiento, F.P.5
Palinski, W.6
-
32
-
-
0037154324
-
1-type angiotensin receptor in oxidative stress and atherogenesis: Part I: Oxidative stress and atherogenesis
-
DOI 10.1161/hc0302.102618
-
Nickenig G, Harrison DG. The AT1-type angiotensin receptor in oxidative stress and atherosclerosis. Part I: oxidative stress and atherogenesis. Circulation 105: 393-396, 2002. (Pubitemid 34106191)
-
(2002)
Circulation
, vol.105
, Issue.3
, pp. 393-396
-
-
Nickenig, G.1
Harrison, D.G.2
-
33
-
-
46749118458
-
Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease
-
Pacher P, Szabo C. Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease. Am J Pathol 173: 2-13, 2008.
-
(2008)
Am J Pathol
, vol.173
, pp. 2-13
-
-
Pacher, P.1
Szabo, C.2
-
34
-
-
36248935988
-
Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain
-
DOI 10.1038/sj.jcbfm.9600491, PII 9600491
-
Park L, Anrather J, Girouard H, Zhou P, Iadecola C. Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain. J Cereb Blood Flow Metab 27: 1908-1918, 2007. (Pubitemid 350129160)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.12
, pp. 1908-1918
-
-
Park, L.1
Anrather, J.2
Girouard, H.3
Zhou, P.4
Iadecola, C.5
-
35
-
-
39549106246
-
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
-
Park L, Zhou P, Pitstick R, Capone C, Anrather J, Norris EH, Younkin L, Younkin S, Carlson G, McEwen BS, Iadecola C. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci USA 105: 1347-1352, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1347-1352
-
-
Park, L.1
Zhou, P.2
Pitstick, R.3
Capone, C.4
Anrather, J.5
Norris, E.H.6
Younkin, L.7
Younkin, S.8
Carlson, G.9
McEwen, B.S.10
Iadecola, C.11
-
36
-
-
27844562639
-
Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study)
-
DOI 10.1016/S0140-6736(05)67702-1, PII S0140673605677021
-
Rothwell PM, Coull AJ, Silver LE, Fairhead JF, Giles MF, Lovelock CE, Redgrave JN, Bull LM, Welch SJ, Cuthbertson FC, Binney LE, Gutnikov SA, Anslow P, Banning AP, Mant D, Mehta Z. The Oxford Vascular Study. Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). Lancet 366: 1773-1783, 2005. (Pubitemid 41642641)
-
(2005)
Lancet
, vol.366
, Issue.9499
, pp. 1773-1783
-
-
Rothwell, P.M.1
Coull, A.J.2
Silver, L.E.3
Fairhead, J.F.4
Giles, M.F.5
Lovelock, C.E.6
Redgrave, J.N.E.7
Bull, L.M.8
Welch, S.J.V.9
Cuthbertson, F.C.10
Binney, L.E.11
Gutnikov, S.A.12
Anslow, P.13
Banning, A.P.14
Mant, D.15
Mehta, Z.16
-
37
-
-
0036144727
-
Endothelial dysfunction and blood pressure variability in selected inbred mouse strains
-
DOI 10.1161/hq0102.101098
-
Ryan MJ, Didion SP, Davis DR, Faraci FM, Sigmund CD. Endothelial dysfunction and blood pressure variability in selected inbred mouse strains. Arterioscler Thromb Vasc Biol 22: 42-48, 2002. (Pubitemid 34076230)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.1
, pp. 42-48
-
-
Ryan, M.J.1
Didion, S.P.2
Davis, D.R.3
Faraci, F.M.4
Sigmund, C.D.5
-
38
-
-
0033969820
-
Age-related impairment of coupling mechanism between neuronal activation and functional cerebral blood flow response was restored by cholinesterase inhibition: PET study with microdialysis in the awake monkey brain
-
DOI 10.1016/S0006-8993(99)02394-X, PII S000689939902394X
-
Tsukada H, Sato K, Kakiuchi T, Nishiyama S. Age-related impairment of coupling mechanism between neuronal activation and functional cerebral blood flow response was restored by cholinesterase inhibition: PET study with microdialysis in the awake monkey brain. Brain Res 857: 158-164, 2000. (Pubitemid 30107801)
-
(2000)
Brain Research
, vol.857
, Issue.1-2
, pp. 158-164
-
-
Tsukada, H.1
Sato, K.2
Kakiuchi, T.3
Nishiyama, S.4
-
39
-
-
33846855776
-
Oxidative stress in the aging murine olfactory bulb: Redox proteomics and cellular localization
-
DOI 10.1002/jnr.21130
-
Vaishnav RA, Getchell ML, Poon HF, Barnett KR, Hunter SA, Pierce WM, Klein JB, Butterfield DA, Getchell TV. Oxidative stress in the aging murine olfactory bulb: redox proteomics and cellular localization. J Neurosci Res 85: 373-385, 2007. (Pubitemid 46219305)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.2
, pp. 373-385
-
-
Vaishnav, R.A.1
Getchell, M.L.2
Poon, H.F.3
Barnett, K.R.4
Hunter, S.A.5
Pierce, W.M.6
Klein, J.B.7
Butterfield, D.A.8
Getchell, T.V.9
-
40
-
-
0038119606
-
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates
-
DOI 10.1161/01.HYP.0000073843.56046.45
-
Wang M, Takagi G, Asai K, Resuello RG, Natividad FF, Vatner DE, Vatner SF, Lakatta EG. Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates. Hypertension 41: 1308-1316, 2003. (Pubitemid 36706082)
-
(2003)
Hypertension
, vol.41
, Issue.6
, pp. 1308-1316
-
-
Wang, M.1
Takagi, G.2
Asai, K.3
Resuello, R.G.4
Natividad, F.F.5
Vatner, D.E.6
Vatner, S.F.7
Lakatta, E.G.8
-
41
-
-
34250816941
-
Proinflammatory profile within the grossly normal aged human aortic wall
-
DOI 10.1161/HYPERTENSIONAHA.107.089409
-
Wang M, Zhang J, Jiang LQ, Spinetti G, Pintus G, Monticone R, Kolodgie FD, Virmani R, Lakatta EG. Proinflammatory profile within the grossly normal aged human aortic wall. Hypertension 50: 219-227, 2007. (Pubitemid 46986044)
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 219-227
-
-
Wang, M.1
Zhang, J.2
Jiang, L.-Q.3
Spinetti, G.4
Pintus, G.5
Monticone, R.6
Kolodgie, F.D.7
Virmani, R.8
Lakatta, E.G.9
-
42
-
-
0035923532
-
5 muscarinic acetylcholine receptor knockout mice
-
DOI 10.1073/pnas.251542998
-
Yamada M, Lamping KG, Duttaroy A, Zhang W, Cui Y, Bymasterm FP, McKinzie DL, Felder CC, Deng CX, Faraci FM, Wess J. Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice. Proc Natl Acad Sci USA 98: 14096-14101, 2001. (Pubitemid 33116030)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.24
, pp. 14096-14101
-
-
Yamada, M.1
Lamping, K.G.2
Duttaroy, A.3
Zhang, W.4
Cui, Y.5
Bymaster, F.P.6
McKinzie, D.L.7
Felder, C.C.8
Deng, C.-X.9
Faraci, F.M.10
Wess, J.11
|