Baroreceptor reflex regulation in anesthetized transgenic rats with low glia-derived angiotensinogen

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 3, 2007, Pages

  Sakima, Atsushi ^a   Averill, David B ^a   Kasper, Sherry O ^a   Jackson, LaRhonda ^a   Ganten, Detlev ^b   Ferrario, Carlos M ^a   Gallagher, Patricia E ^a   Diz, Debra I ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Baroreceptors; Brain renin angiotensin system; Solitary tract nucleus; Transgenic rats

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; CANDESARTAN; CHLORALOSE; MESSENGER RNA; URETHAN;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GLIA; HEART RATE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOLITARY TRACT NUCLEUS; TRANSGENIC RAT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSINOGEN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BAROREFLEX; BENZIMIDAZOLES; BLOOD PRESSURE; BRAIN; HEART RATE; MALE; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SOLITARY NUCLEUS; TETRAZOLES;

EID: 33847719904     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00984.2006     Document Type: Article

References (64)

1. Averill DB, Diz DI. Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata. Brain Res Bull 51: 119-128, 2001.
2. Baltatu O, Fontes MA, Campagnole-Santos MJ, Caligiorni S, Ganten D, Santos RA, Bader M. Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen. Am J Physiol Regul Integr Comp Physiol 280: R428-R433, 2001.
3. Baltatu O, Janssen BJ, Bricca G, Plehm R, Monti J, Ganten D, Bader M. Alterations of blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen. Hypertension 37: 408-413, 2001.
4. Barnes KL, Diz DI, Ferrario CM. Functional interactions between angiotensin II and substance P in the dorsal medulla. Hypertension 17: 1121-1126, 1991.
5. Barnes KL, Knowles WD, Ferrario CM. Angiotensin II and angiotensin-(1-7) excite neurons in the canine medulla in vitro. Brain Res Bull 24: 275-280, 1990.
6. Britto RR, Santos RA, Fagundes-Moura CR, Khosla MC, Campagnole-Santos MJ. Role of angiotensin-(1-7) in the modulation of the baroreflex in renovascular hypertensive rats. Hypertension 30: 549-556, 1997.
7. Campagnole-Santos MJ, Diz DI, Ferrario CM. Actions of angiotensin peptides after partial denervation of the solitary tract nucleus. Hypertension 15 Suppl I: I-34 -I-39, 1990.
8. Campagnole-Santos MJ, Diz DI, Ferrario CM. Baroreflex reflex modulation by angiotensin II at the nucleus tractus solitarii. Hypertension 11 Suppl I: I-167-I-171, 1988.
9. Campagnole-Santos MJ, Heringer SB, Batista EN, Khosla MC, Santos RA. Differential baroreceptor reflex modulation by centrally infused angiotensin peptides. Am J Physiol Regul Integr Comp Physiol 263: R89-R94, 1992.
10. Campos LA, Couto AS, Iliescu R, Santos JA, Santos RA, Ganten D, Campagnole-Santos MJ, Bader M, Baltatu O. Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen. Regul Pept 119: 177-182, 2004.
11. Casto R, Phillips MI. Angiotensin II attenuates the baroreflexes at nucleus tractus solitarius of rats. Am J Physiol Regul Integr Comp Physiol 250: R193-R198, 1986.
12. Chappell MC, Brosnihan KB, Diz DI, Ferrario CM. Identification of angiotensin-(1-7) in rat brain: evidence for differential processing of angiotensin peptides. J Biol Chem 264: 16518-16521, 1989.
13. Chaves GZ, Caligiorne SM, Santos RA, Khosla MC, Campagnole-Santos MJ. Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats. J Hypertens 18: 1841-1848, 2000.
14. Couto AS, Baltatu O, Santos RA, Ganten D, Bader M, Campagnole-Santos MJ. Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen. J Hypertens 20: 919-925, 2002.
15. Davisson RL. Physiological genomic analysis of the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 285: R498-R511, 2003.
16. Deschepper CF, Bouhnik J, Ganong WF. Colocalization of angiotensinogen and glial fibrillary acidic protein in astrocytes of rat brain. Brain Res 374: 195-198, 1986.
17. DiBona GF. Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium. Acta Physiol Scand 177: 285-289, 2003.
18. Diz DI, Barnes KL, Ferrario CM. Hypotensive actions of microinjections of angiotensin II into the dorsal motor nucleus of the vagus. J Hypertens 2: 53-56, 1984.
19. Diz DI, Fantz DL, Benter IF, Bosch SM. Acute depressor actions of angiotensin II in the nucleus of the solitary tract are mediated by substance P. Am J Physiol Regul Integr Comp Physiol 273: R28-R34, 1997.
20. Diz DI, Ferrario CM. Angiotensin receptor heterogeneity in the dorsal medulla oblongata as defined by angiotensin-(1-7). In: Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors, edited by Sumners PR. New York: Plenum, 1996, p. 225-235.
21. Diz DI, Jessup JA, Westwood BM, Bosch SM, Vinsant S, Gallagher PE, Averill DB. Angiotensin peptides as neurotransmitters/neuromodulators in the dorsomedial medulla. Clin Exp Pharmacol Physiol 29: 473-482, 2001.
22. Diz DI, Kasper SO, Sakima A, Ferrario CM. Aging and the brain renin-angiotensin system: insights from studies in transgenic rats. Cleve Clin J. In press.
23. Diz DI, Pirro N. Differential actions of angiotensin II and angiotensin-(1-7) on transmitter release. Hypertension 19 Suppl II: II-41-II-48, 1992.
24. 1 antisense distinguishes receptors mediating angiotensin II actions in solitary tract nucleus. Hypertension 37: 1292-1297, 2001.
25. 1 receptor antagonist blocks angiotensin II responses in renin transgenic rat medulla oblongata. Hypertension 31: 473-479, 1998.
26. Eshima K, Hirooka Y, Shigematsu H, Matsuo I, Koike G, Sakai K, Takeshita A. Angiotensin in the nucleus tractus solitarii contributes to neurogenic hypertension caused by chronic nitric oxide synthase inhibition. Hypertension 36: 259-263, 2000.
27. Felix D, Khosla MC, Barnes KL, Imboden H, Montani B, Ferrario CM. Neurophysiological responses to angiotensin-(1-7). Hypertension 17: 1111-1114, 1991.
28. Fontes MA, Baltatu O, Caligiorne SM, Campagnole-Santos MJ, Ganten D, Bader M, Santos RA. Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats. Physiol Genomics 2: 137-142, 2000.
29. Gallagher PE, Li P, Lenhart JR, Chappell MC, Brosnihan KB. Estrogen regulation of angiotensin-converting enzyme mRNA. Hypertension 33: 323-329, 1999.
30. 1 receptors in the central control of sympathetic vasomotor function. Clin Exp Pharmacol Physiol Suppl 3: S93-S98, 1996.
31. + and ouabain are attenuated in transgenic rats deficient in brain angiotensinogen. Hypertension 37: 683-686, 2001.
32. Jackson L, Sakima A, Oden SD, Tommasi EN, Ganten D, Ferrario CM, Diz DI. Angiotensin receptor density in dorsomedial medulla under varying local angiotensin levels during aging (Abstract). Hypertension 44: 516, 2004.
33. Kasparov S, Paton JF. Differential effects of angiotensin II in the nucleus tractus solitarii of the rat - plausible neuronal mechanisms. J Physiol 521: 227-238, 1999.
34. Kasper SO, Carter CS, Ferrario CM, Ganten D, Ferder LF, Sonntag WE, Gallagher PE, Diz DI. Growth and metabolism disturbances in transgenic rats with altered renin-angiotensin system expression. Physiol Genomics 23: 311-317, 2005.
35. 1 receptors in the SFO and PVN. Neurotoxicity Res 6: 259-265, 2004.
36. Kasper SO, Sakima A, Ferrario CM, Ganten D, Diz DI. Altered stress responses in rats with low glial angiotensinogen. Am J Med Sci. 321: 225-236, 2001.
37. Lavoie JL, Cassell MD, Gross KW, Sigmund CD. Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model. Hypertension 43: 1116-1119, 2004.
38. Lynch KR, Hawelu-Johnson CL, Guyenet PG. Localization of brain angiotensinogen mRNA by hybridization histochemistry. Mol Brain Res 2: 149-158, 1987.
39. Matsukawa K, Ninomiya I. Anesthetic effects on tonic and reflex renal sympathetic nerve activity in awake cats. Am J Physiol Regul Integr Comp Physiol 257: R371-R378, 1989.
40. 1 receptors in the nucleus of the solitary tract to attenuate the baroreceptor reflex. Am J Physiol Regul Integr Comp Physiol 275: R1611-R1619, 1998.
41. Michelini LC, Bonagamba LG. Angiotensin II as a modulator of the baroreceptor reflex in the brain stem of conscious rats. Hypertension 11 Suppl I: I75-I79, 1988.
42. Morimoto S, Cassell MD, Sigmund CD. Neuron-specific expression of human angiotensinogen in brain causes increased salt appetite. Physiol Genomics 9: 113-120, 2002.
43. Morimoto S, Cassell MD, Sigmund CD. Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. J Biol Chem 277: 33235-33241, 2002.
44. Oliveria DR, Santos RA, Santos GF, Khosla MC, Campagnole-Santos MJ. Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats. Hypertension 27: 1284-1290, 1996.
45. Panzenbeck MJ, Tan W, Hajdu MA, Zucker IH. Prostaglandins mediate the increased sensitivity of left ventricular reflexes after captopril treatment in conscious dogs. J Pharmacol Exp Ther 244: 384-390, 1988.
46. Paton JF, Kasparov S. Differential effects of angiotensin II on cardiorespiratory reflexes mediated by nucleus tractus solitarii - a microinjection study in the rat. J Physiol 521: 213-225, 1999.
47. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. Orlando, FL: Academic, 1986.
48. Potts PD, Allen AM, Horiuchi J, Dampney RA. Does angiotensin II have a significant tonic action on cardiovascular neurons in the rostral and caudal VLM? Am J Physiol Regul Integr Comp Physiol 279: R1392-R1402, 2000.
49. Potts PD, Horiuchi J, Coleman MJ, Dampney RA. The cardiovascular effects of angiotensin-(1-7) in the rostral and caudal ventrolateral medulla of the rabbit. Brain Res 877: 58-64, 2000.
50. Raizada MK, Sumners C, Lu D. Angiotensin II type 1 receptor mRNA levels in the brains of normotensive and spontaneously hypertensive rats. J Neurochem 60: 1949-1952, 1993.
51. Sakai K, Chapleau MW, Morimoto S, Cassell MD, Sigmund CD. Differential modulation of baroreflex control of heart rate by neuron- vs. glia-derived angiotensin II. Physiol Genomics 20: 66-72, 2004.
52. Sakima A, Averill DB, Gallagher PE, Kasper SO, Tommasi EN, Ferrario CM, Diz DI. Impaired heart rate baroreflex in older rats. Role of endogenous angiotensin-(1-7) at the nucleus tractus solitarii. Hypertension 46: 333-340, 2005.
53. Sakima A, Averill DB, Kasper SO, Tommasi E, Gilliam-Davis S, Jackson L, Ganten D, Ferrario CM, Diz DI. Cardiovascular and autonomic control in transgenic rats with low glial-derived angiotensinogen. International Soc Hyperten 157: PM3-03-01, 2006.
54. Schinke M, Baltatu O, Bohm M, Peters J, Rascher W, Bricca G, Lippoldt A, Ganten D, Bader M. Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen. Proc Natl Acad Sci USA 96: 3975-3980, 1999.
55. Sernia C, Zeng T, Kerr D, Wyse B. Novel perspectives in pituitary and brain angiotensinogen. Front Neuroendocrinol 18: 174-208, 1997.
56. Shigematsu H, Hirooka Y, Eshima K, Shihara M, Tagawa T, Takeshita A. Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt. Am J Physiol Regul Integr Comp Physiol 280: R1665-R1673, 2001.
57. Shimokawa A, Kunitake T, Takasaki M, Kannan H. Differential effects of anesthetics on sympathetic nerve activity and arterial baroreceptor reflex in chronically instrumented rats. J Auton Nerv Syst 72: 46-54, 1998.
58. 1 receptors mediate excitatory inputs to RVLM pressor neurons from hypothalamus. Hypertension 34: 1301-1307, 1999.
59. Tamura T, Yokoyama N, Sumida Y, Fujita T, Chiva E, Tamura N, Kobayashi S, Kihara M, Murakami K, Horiuchi M, Umemura S. Tissue-specific changes of type 1 angiotensin II receptor and angiotensin-converting enzyme mRNA in angiotensin gene-knockout mice. J Endocrinol 160: 401-408, 1999.
60. Thomas WG, Greenland KJ, Shinkel TA, Sernia C. Angiotensinogen is secreted by pure rat neuronal cell cultures. Brain Res 488: 191-200, 1992.
61. Vinsant S, Chappell MC, Ferrario CM, Ganten D, Diz DI. Low glial angiotensinogen is not associated with deficits in angiotensin peptides in neuronal pathways in transgenic ASrAogen rats (Abstract). FASEB J 19: A1188, 2005.
62. Wang H, Huang BS, Ganten D, Leenen FH. Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen. Circ Res 94: 843-849, 2004.
63. Widdop RE, Krstew E, Jarrott B. Temperature dependence of angiotensin II-mediated depolarisation of the rat isolated nodose ganglion. Eur J Pharmacol 185: 107-111, 1990.
64. Widdop RE, Krstew E, Jarrott B. Electrophysiological responses of angiotensin peptides on the rat isolated nodose ganglion. Clin Exp Hypertens A Theory Practice 14: 597-613, 1992.