Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; Possibilities and limitations for targeting with trypanocidal drugs

Parasitology

Volumn 140, Issue 1, 2013, Pages 1-20

  Gualdrón López, Melisa ^a   Brennand, Ana ^a   Avilán, Luisana ^b   Michels, Paul A M ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b FACULTAD DE CIENCIAS   (Venezuela)

Author keywords

ABC transporters; channels; drug targeting; glycosomal membrane; glycosome; matrix protein import; metabolite channelling; multi enzyme complex; solute translocation; trypanosomes

Indexed keywords

ABC TRANSPORTER; ACYL COENZYME A; ADENOSINE DERIVATIVE; ANTITRYPANOSOMAL AGENT; BENZALDEHYDE DERIVATIVE; BISPHOSPHONIC ACID DERIVATIVE; CYTOSOL RECEPTOR; EBSELEN; MATRIX PROTEIN; PEROXIN; QUERCETIN;

AFRICAN TRYPANOSOMIASIS; CELL MEMBRANE; CELL ORGANELLE; DRUG TARGETING; GLUCONEOGENESIS; GLYCOLYSIS; GLYCOSOME; HUMAN; IC 50; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

ANIMALS; BIOLOGICAL TRANSPORT; DRUG DISCOVERY; HUMANS; INTRACELLULAR MEMBRANES; MICROBODIES; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; TRYPANOCIDAL AGENTS; TRYPANOSOMA;

KINETOPLASTIDA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

EID: 84872039252     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182012001278     Document Type: Review

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