Genetic validation of aldolase and glyceraldehyde-3-phosphate dehydrogenase as drug targets in Trypanosoma brucei

Molecular and Biochemical Parasitology

Volumn 169, Issue 1, 2010, Pages 50-54

  Cáceres, Ana Judith ^a   Michels, Paul A M ^b   Hannaert, Véronique ^b  

^a FACULTAD DE CIENCIAS   (Venezuela)

^b DE DUVE INSTITUTE   (Belgium)

Author keywords

Aldolase; Glyceraldehyde 3 phosphate dehydrogenase; Glycolysis; RNA interference; Trypanosomes

Indexed keywords

FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME STRUCTURE; GENETIC ANALYSIS; GLUCOSE INTAKE; GLYCOLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTOZOAL GENETICS; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; TRYPANOSOMA BRUCEI;

ANIMALS; CELL LINE; FRUCTOSE-BISPHOSPHATE ALDOLASE; GENE KNOCKDOWN TECHNIQUES; GENETIC VARIATION; GLUCOSE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GLYCOLYSIS; HUMANS; PROTOZOAN PROTEINS; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

TRYPANOSOMA BRUCEI;

EID: 71549138698     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.09.001     Document Type: Article

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