Diapause Formation and Downregulation of Insulin-Like Signaling via DAF-16/FOXO Delays Axonal Degeneration and Neuronal Loss

PLoS Genetics

Volumn 8, Issue 12, 2012, Pages

  Calixto, Andrea ^a,c   Jara, Juan S ^a   Court, Felipe A ^a,b  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b Neurounion Biomedical Foundation   (Chile)

^c UNIVERSIDAD MAYOR   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CATALASE; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO;

ARTICLE; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; CELL LOSS; CONTROLLED STUDY; DIAPAUSE; DOWN REGULATION; ENZYME INDUCTION; FUNCTIONAL MORPHOLOGY; INTRACELLULAR SIGNALING; METABOLIC REGULATION; MOUSE; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ANIMALS; AXONS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM; CATALASE; GENE EXPRESSION REGULATION; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; NEURONS; NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS; MAMMALIA; MUS; WALLERIA;

EID: 84872038812     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003141     Document Type: Article

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