p38α inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species

Cancer Research

Volumn 73, Issue 1, 2013, Pages 215-224

  Sakurai, Toshiharu ^a,b   Kudo, Masatoshi ^a   Umemura, Atsushi ^b   He, Guobin ^b   Elsharkawy, Ahmed M ^b,d   Seki, Ekihiro ^c   Karin, Michael ^b  

^a KINKI UNIVERSITY   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GANKYRIN; HEAT SHOCK PROTEIN 27; MEMBRANE PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOACCUMULATION; CANCER INHIBITION; CANCER RECURRENCE; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROGENESIS; GENE; GENE TARGETING; HSP25 GENE; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER FIBROSIS; LIVER INJURY; LIVER METABOLISM; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; XENOBIOTIC METABOLISM;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 14; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84871984069     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-1602     Document Type: Article

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