-
2
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002;31:339-346.
-
(2002)
Nat Genet
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
3
-
-
0033630490
-
Differentiation mechanisms and malignancy
-
Abelev GI. Differentiation mechanisms and malignancy. Biochemistry (Moscow) 2000;65:107-116.
-
(2000)
Biochemistry (Moscow)
, vol.65
, pp. 107-116
-
-
Abelev, G.I.1
-
4
-
-
0026928723
-
HNF1, a homeoprotein member of the hepatic transcription regulatory network
-
Tronche F, Yaniv M. HNF1, a homeoprotein member of the hepatic transcription regulatory network. Bioessays 1992;14:579-587.
-
(1992)
Bioessays
, vol.14
, pp. 579-587
-
-
Tronche, F.1
Yaniv, M.2
-
5
-
-
1842621473
-
Tissue-specific regulation by transcription factors
-
Locker J, ed. Oxford: BIOS Scientific Publishers Ltd
-
Locker J. Tissue-specific regulation by transcription factors. In: Locker J, ed. Transcription factors. Oxford: BIOS Scientific Publishers Ltd, 2001: 237-262.
-
(2001)
Transcription Factors
, pp. 237-262
-
-
Locker, J.1
-
6
-
-
0029962261
-
Liver-enriched transcription factors and hepatocyte differentiation
-
Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J 1996;10:267-282.
-
(1996)
FASEB J
, vol.10
, pp. 267-282
-
-
Cereghini, S.1
-
7
-
-
0033630189
-
Molecular mechanisms of alpha-fetoprotein gene expression
-
Lazarevich NL. Molecular mechanisms of alpha-fetoprotein gene expression. Biochemstry (Moscow) 2000;65:117-133.
-
(2000)
Biochemstry (Moscow)
, vol.65
, pp. 117-133
-
-
Lazarevich, N.L.1
-
8
-
-
0036200587
-
Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
-
Schrem H, Klempnauer J, Borlak J. Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol Rev 2002;54:129-158.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 129-158
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
9
-
-
0034090310
-
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
-
Li J, Ning G, Duncan SA. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev 2000;14:464-474.
-
(2000)
Genes Dev
, vol.14
, pp. 464-474
-
-
Li, J.1
Ning, G.2
Duncan, S.A.3
-
10
-
-
0035141324
-
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
-
Hayhurst GP, Lee YH, Lambert G, Ward JM, Gonzalez FJ. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol 2001;21: 1393-1403.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1393-1403
-
-
Hayhurst, G.P.1
Lee, Y.H.2
Lambert, G.3
Ward, J.M.4
Gonzalez, F.J.5
-
11
-
-
0038757830
-
Hepatocyte nuclear factor 4 alpha controls the development of a hepatic epithelium and liver morphogenesis
-
Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, Kaestner KH, et al. Hepatocyte nuclear factor 4 alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet 2003; 34:292-296.
-
(2003)
Nat Genet
, vol.34
, pp. 292-296
-
-
Parviz, F.1
Matullo, C.2
Garrison, W.D.3
Savatski, L.4
Adamson, J.W.5
Ning, G.6
Kaestner, K.H.7
-
12
-
-
0028914210
-
Expression of the liver-enriched transcription factors C/EBP alpha, C/ EBP beta, HNF-1, and HNF-4 in preneoplastic nodules and hepatocellular carcinoma in rat liver
-
Flodby P, Liao DZ, Blanck A, Xanthopoulos KG, Hallstrom IP. Expression of the liver-enriched transcription factors C/EBP alpha, C/EBP beta, HNF-1, and HNF-4 in preneoplastic nodules and hepatocellular carcinoma in rat liver. Mol Carcinog 1995;12:103-109.
-
(1995)
Mol Carcinog
, vol.12
, pp. 103-109
-
-
Flodby, P.1
Liao, D.Z.2
Blanck, A.3
Xanthopoulos, K.G.4
Hallstrom, I.P.5
-
13
-
-
0028799497
-
The DNA binding activity of the liver transcription factors LFB1 (HNF1) and HNF4 varies coordinately in rat hepatocellular carcinoma
-
Stumpf H, Senkel S, Rabes HM, Ryffel GU. The DNA binding activity of the liver transcription factors LFB1 (HNF1) and HNF4 varies coordinately in rat hepatocellular carcinoma. Carcinogenesis 1995;16:143-145.
-
(1995)
Carcinogenesis
, vol.16
, pp. 143-145
-
-
Stumpf, H.1
Senkel, S.2
Rabes, H.M.3
Ryffel, G.U.4
-
14
-
-
0029915773
-
Expression of hepatocyte-enriched nuclear transcription factors in mouse liver tumours
-
Kalkuhl A, Kaestner K, Buchmann A, Schwarz M. Expression of hepatocyte-enriched nuclear transcription factors in mouse liver tumours. Carcinogenesis 1996;17:609-612.
-
(1996)
Carcinogenesis
, vol.17
, pp. 609-612
-
-
Kalkuhl, A.1
Kaestner, K.2
Buchmann, A.3
Schwarz, M.4
-
15
-
-
0035300430
-
Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma
-
Xu L, Hui L, Wang S, Gong J, Jin Y, Wang Y, Ji Y, et al. Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma. Cancer Res 2001;61:3176-3181.
-
(2001)
Cancer Res
, vol.61
, pp. 3176-3181
-
-
Xu, L.1
Hui, L.2
Wang, S.3
Gong, J.4
Jin, Y.5
Wang, Y.6
Ji, Y.7
-
16
-
-
0034180450
-
Rapid progression of transplantable mouse hepatocarcinoma associated with the loss of cell-surface polarity
-
Engelhardt NV, Kudryavtseva EI, Morozova OV, Rudinskaya TD, Turusov VS. Rapid progression of transplantable mouse hepatocarcinoma associated with the loss of cell-surface polarity. Arkh Patol (Russ) 2000;62: 24-29.
-
(2000)
Arkh Patol (Russ)
, vol.62
, pp. 24-29
-
-
Engelhardt, N.V.1
Kudryavtseva, E.I.2
Morozova, O.V.3
Rudinskaya, T.D.4
Turusov, V.S.5
-
17
-
-
0025690311
-
Liver-enriched transcription factor HNF4 is a novel member of the steroid hormone receptor superfamily
-
Sladek FM, Zhong W, Lai E, Darnell Jr JE. Liver-enriched transcription factor HNF4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990;4:2353-2364.
-
(1990)
Genes Dev
, vol.4
, pp. 2353-2364
-
-
Sladek, F.M.1
Zhong, W.2
Lai, E.3
Darnell Jr., J.E.4
-
18
-
-
0030695445
-
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism
-
Stoffel M, Duncan SA. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci U S A 1997;94:13209-13214.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13209-13214
-
-
Stoffel, M.1
Duncan, S.A.2
-
19
-
-
0031054568
-
Murine gastrulation requires HNF4 regulated gene expression in the visceral endoderm: Tetraploid rescue of HNF4-/- embryos
-
Duncan SA, Nagy A, Chan W. Murine gastrulation requires HNF4 regulated gene expression in the visceral endoderm: tetraploid rescue of HNF4-/- embryos. Development 1997;124:279-287.
-
(1997)
Development
, vol.124
, pp. 279-287
-
-
Duncan, S.A.1
Nagy, A.2
Chan, W.3
-
20
-
-
0035408885
-
Disturbances of intercellular contacts and interaction of cells with extracellular matrix in the rapidly growing mouse hepatocarcinoma
-
Kudryavtseva EI, Morozova OV, Rudinskaya TD, Engelhardt NV. Disturbances of intercellular contacts and interaction of cells with extracellular matrix in the rapidly growing mouse hepatocarcinoma. Ark Patol (Russ) 2001;63:33-37.
-
(2001)
Ark Patol (Russ)
, vol.63
, pp. 33-37
-
-
Kudryavtseva, E.I.1
Morozova, O.V.2
Rudinskaya, T.D.3
Engelhardt, N.V.4
-
21
-
-
0030743347
-
Advances in quantification and characterization of telomerase activity by telomeric repeat amplification protocol (TRAP)
-
Kim NW, Wu F. Advances in quantification and characterization of telomerase activity by telomeric repeat amplification protocol (TRAP). Nucl Acids Res 1997;25:2595-2597.
-
(1997)
Nucl Acids Res
, vol.25
, pp. 2595-2597
-
-
Kim, N.W.1
Wu, F.2
-
22
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, Garcia De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol 2000;2:84-89.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Franci, C.3
Dominguez, D.4
Monfar, M.5
Baulida, J.6
Garcia De Herreros, A.7
-
23
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, Portillo F, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2000;2:76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
Del Barrio, M.G.6
Portillo, F.7
-
24
-
-
0031595551
-
Alpha3beta1-integrin as a critical mediator of the hepatic differentiation response to the extracellular matrix
-
Lora JM, Rowader KE, Soares L, Giancotti F, Zaret KS. Alpha3beta1-integrin as a critical mediator of the hepatic differentiation response to the extracellular matrix. HEPATOLOGY 1998;28:1095-1104.
-
(1998)
HEPATOLOGY
, vol.28
, pp. 1095-1104
-
-
Lora, J.M.1
Rowader, K.E.2
Soares, L.3
Giancotti, F.4
Zaret, K.S.5
-
25
-
-
0036317838
-
Transforming growth factor-beta1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin
-
Giannelli G, Fransvea E, Marinosci F, Bergamini C, Colucci S, Schiraldi O, Antonaci S. Transforming growth factor-beta1 triggers hepatocellular carcinoma invasiveness via alpha3beta1 integrin. Am J Pathol 2002;161: 183-193.
-
(2002)
Am J Pathol
, vol.161
, pp. 183-193
-
-
Giannelli, G.1
Fransvea, E.2
Marinosci, F.3
Bergamini, C.4
Colucci, S.5
Schiraldi, O.6
Antonaci, S.7
-
26
-
-
0037220834
-
B-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
-
Monga SPS, Monga HK, Tan X, Mulé K, Pediaditakis P, Michalopoulos GK. B-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology 2003;124: 202-216.
-
(2003)
Gastroenterology
, vol.124
, pp. 202-216
-
-
Monga, S.P.S.1
Monga, H.K.2
Tan, X.3
Mulé, K.4
Pediaditakis, P.5
Michalopoulos, G.K.6
-
27
-
-
0032991680
-
Cellular aspects of alpha-fetoprotein reexpression in tumors
-
Abelev GI, Eraiser TL. Cellular aspects of alpha-fetoprotein reexpression in tumors. Semin Cancer Biol 1999;9:95-107.
-
(1999)
Semin Cancer Biol
, vol.9
, pp. 95-107
-
-
Abelev, G.I.1
Eraiser, T.L.2
-
28
-
-
0037213346
-
Mechanisms controlling early development of the liver
-
Duncan SA. Mechanisms controlling early development of the liver. Mech Dev 2003;120:19-33.
-
(2003)
Mech Dev
, vol.120
, pp. 19-33
-
-
Duncan, S.A.1
-
29
-
-
0029981643
-
Chicken ovalbumin upstream promoter-transcription factors and their regulation
-
Qiu Y, Krishnan V, Pereira FA, Tsai SY, Tsai MJ. Chicken ovalbumin upstream promoter-transcription factors and their regulation. J Steroid Biochem Mol Biol 1996;56:81-85.
-
(1996)
J Steroid Biochem Mol Biol
, vol.56
, pp. 81-85
-
-
Qiu, Y.1
Krishnan, V.2
Pereira, F.A.3
Tsai, S.Y.4
Tsai, M.J.5
-
30
-
-
0034747205
-
Expression of HNF4a isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3 end splicing
-
Torres-Padilla ME, Fougere-Deschatrette C, Weiss MC. Expression of HNF4a isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3 end splicing. Mech Dev 2001;109:183-193.
-
(2001)
Mech Dev
, vol.109
, pp. 183-193
-
-
Torres-Padilla, M.E.1
Fougere-Deschatrette, C.2
Weiss, M.C.3
-
31
-
-
0032559647
-
Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells
-
Spath GF, Weiss MC. Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells. J Cell Biol 1998;140:935-946.
-
(1998)
J Cell Biol
, vol.140
, pp. 935-946
-
-
Spath, G.F.1
Weiss, M.C.2
-
32
-
-
0024061257
-
A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells
-
Cereghini S, Blumenfeld M, Yaniv M. A liver-specific factor essential for albumin transcription differs between differentiated and dedifferentiated rat hepatoma cells. Genes Dev 1988;2:957-974.
-
(1988)
Genes Dev
, vol.2
, pp. 957-974
-
-
Cereghini, S.1
Blumenfeld, M.2
Yaniv, M.3
-
33
-
-
0032518210
-
An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types
-
Nakhei H, Lingott A, Lemm I, Ryffel GU. An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types. Nucl Acids Res 1998;26:497-504.
-
(1998)
Nucl Acids Res
, vol.26
, pp. 497-504
-
-
Nakhei, H.1
Lingott, A.2
Lemm, I.3
Ryffel, G.U.4
-
34
-
-
0027204617
-
HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids
-
Griffo G, Hamon-Benais C, Angrand PO, Fox M, West L, Lecoq O, Povey S, et al. HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids. J Cell Biol 1993;121:887-898.
-
(1993)
J Cell Biol
, vol.121
, pp. 887-898
-
-
Griffo, G.1
Hamon-Benais, C.2
Angrand, P.O.3
Fox, M.4
West, L.5
Lecoq, O.6
Povey, S.7
-
35
-
-
0030785641
-
Hepatocyte nuclear factor-4 prevents silencing of hepatocyte nuclear factor-1 expression in hepatoma x fibroblast cell hybrids
-
Bulla GA. Hepatocyte nuclear factor-4 prevents silencing of hepatocyte nuclear factor-1 expression in hepatoma x fibroblast cell hybrids. Nucleic Acids Res 1997;25:2501-2508.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2501-2508
-
-
Bulla, G.A.1
-
36
-
-
0031595805
-
Expression of HNF-1 alpha and HNF-1 beta in various histological differentiations of hepatocellular carcinoma
-
Wang W, Hayashi Y, Ninomiya T, Ohta K, Nakabayashi H, Tamaoki T, Itoh H. Expression of HNF-1 alpha and HNF-1 beta in various histological differentiations of hepatocellular carcinoma. J Pathol 1998;184:272-278.
-
(1998)
J Pathol
, vol.184
, pp. 272-278
-
-
Wang, W.1
Hayashi, Y.2
Ninomiya, T.3
Ohta, K.4
Nakabayashi, H.5
Tamaoki, T.6
Itoh, H.7
-
37
-
-
0030022255
-
Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein
-
Watkins PJ, Condreay JP, Huber BE, Jacobs SJ, Adams DJ. Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein. Cancer Res 1996;56:1063-1067.
-
(1996)
Cancer Res
, vol.56
, pp. 1063-1067
-
-
Watkins, P.J.1
Condreay, J.P.2
Huber, B.E.3
Jacobs, S.J.4
Adams, D.J.5
-
38
-
-
0015170823
-
Expression of differentiated functions in hepatoma cell hybrids: Reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes
-
Weiss MC, Chaplain M. Expression of differentiated functions in hepatoma cell hybrids: reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes. Proc Natl Acad Sci U S A 1971;68:3026-3030.
-
(1971)
Proc Natl Acad Sci U S A
, vol.68
, pp. 3026-3030
-
-
Weiss, M.C.1
Chaplain, M.2
-
39
-
-
0022552059
-
Tissue-specific expression of the rat albumin gene: Genetic control of its extinction in microcell hybrids
-
Petit C, Levilliers J, Ott MO, Weiss MC. Tissue-specific expression of the rat albumin gene: genetic control of its extinction in microcell hybrids. Proc Natl Acad Sci U S A 1986;83:2561-2565.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 2561-2565
-
-
Petit, C.1
Levilliers, J.2
Ott, M.O.3
Weiss, M.C.4
-
40
-
-
0021133977
-
A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells
-
Killary AM, Fournier RE. A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells. Cell 1984;38:523-534.
-
(1984)
Cell
, vol.38
, pp. 523-534
-
-
Killary, A.M.1
Fournier, R.E.2
-
41
-
-
0027405827
-
Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcriptional activators
-
Nitsch D, Boshart M, Schutz G. Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcriptional activators. Genes Dev 1993;7:308-319.
-
(1993)
Genes Dev
, vol.7
, pp. 308-319
-
-
Nitsch, D.1
Boshart, M.2
Schutz, G.3
-
42
-
-
0025940335
-
The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase
-
Boshart M, Weih F, Nichols M, Schutz G. The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase. Cell 1991;66:849-859.
-
(1991)
Cell
, vol.66
, pp. 849-859
-
-
Boshart, M.1
Weih, F.2
Nichols, M.3
Schutz, G.4
-
43
-
-
18444397450
-
Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: Antisense, microarray, gene overexpression, and transcription factor decoy
-
Cho-Chung YS, Nesterova M, Becker KG, Srivastava R, Park YG, Lee YN, Cho YS, et al. Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy. Ann NY Acad Sci 2002;968:22-36.
-
(2002)
Ann NY Acad Sci
, vol.968
, pp. 22-36
-
-
Cho-Chung, Y.S.1
Nesterova, M.2
Becker, K.G.3
Srivastava, R.4
Park, Y.G.5
Lee, Y.N.6
Cho, Y.S.7
|