Simultaneous inhibition of COX-2 and activation of PPAR-γ resulted in the same level and pattern of neuroprotection as they were targeted separately

Journal of Molecular Neuroscience

Volumn 49, Issue 1, 2013, Pages 116-129

  Abraki, Shahnaz Babaei ^a   Khalaj, Leila ^a,b   Shaerzadeh, Fatemeh ^a   Khodagholi, Fariba ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ALBORZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

15d PGJ2; Cyclooxygenase 2; Neuroprotection; NF B; Nrf2; PPAR

Indexed keywords

15D PGJ2; 2 CHLORO 5 NITROBENZANILIDE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; HYDROGEN PEROXIDE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; BINDING AFFINITY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; HYPOTHESIS; IMMUNE RESPONSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PC12 CELL; PHEOCHROMOCYTOMA CELL; RAT; SIGNAL TRANSDUCTION;

ANILIDES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CYCLOOXYGENASE 2 INHIBITORS; HYDROGEN PEROXIDE; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; NITROBENZENES; PC12 CELLS; PPAR GAMMA; PROSTAGLANDIN D2; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SULFONAMIDES;

RATTUS;

EID: 84871969754     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9903-5     Document Type: Article

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