Dehydrozingerone, a structural analogue of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells

Journal of Natural Products

Volumn 75, Issue 12, 2012, Pages 2088-2093

  Yogosawa, Shingo ^a   Yamada, Yasumasa ^b   Yasuda, Shusuke ^a   Sun, Qi ^a   Takizawa, Kaori ^a   Sakai, Toshiyuki ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN B; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DEHYDROZINGERONE; PROTEIN P21; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; G2 PHASE CELL CYCLE CHECKPOINT; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; OXIDATIVE STRESS; PROTEIN DEPHOSPHORYLATION; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL DIVISION; COLONIC NEOPLASMS; CURCUMA; CURCUMIN; G2 PHASE; HT29 CELLS; HUMANS; MOLECULAR STRUCTURE; REACTIVE OXYGEN SPECIES; STEREOISOMERISM; STYRENES; ZINGIBERACEAE;

CURCUMA LONGA; ZINGIBER OFFICINALE;

EID: 84871952149     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np300465f     Document Type: Article

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