Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses

International Journal of Oncology

Volumn 39, Issue 2, 2011, Pages 319-328

  Kuo, Chao Lin ^a   Wu, Shan Ying ^a   Ip, Siu Wan ^a   Wu, Ping Ping ^a   Yu, Chun Shu ^a   Yang, Jai Sing ^a   Chen, Po Yuan ^a   Wu, Shin Hwar ^a,b   Chung, Jing Gung ^a,c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c ASIA UNIVERSITY   (Taiwan)

Author keywords

AIF; Apoptotic death; Caspase 3; Curcumin; Human nasopharyngeal carcinoma NPC TW 076 cells; Mitochondrial depolarization

Indexed keywords

CASPASE 3; CURCUMIN; CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE 1; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CALCIUM; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CURCUMIN; CYTOSOL; DNA DAMAGE; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; NASOPHARYNGEAL NEOPLASMS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 79959923588     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1057     Document Type: Article

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