메뉴 건너뛰기




Volumn 73, Issue 1, 2013, Pages 307-318

Targeting truncated retinoid X receptor-α by CF31 induces TNF-α-dependent apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; CASPASE 8; CF31; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P85; PROTEIN P85ALPHA; RETINOID X RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

EID: 84871948626     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2038     Document Type: Article
Times cited : (37)

References (59)
  • 1
    • 0035749803 scopus 로고    scopus 로고
    • The promise of retinoids to fight against cancer
    • Altucci L, Gronemeyer H. The promise of retinoids to fight against cancer. Nat Rev Cancer 2001;1:181-93.
    • (2001) Nat Rev Cancer , vol.1 , pp. 181-193
    • Altucci, L.1    Gronemeyer, H.2
  • 2
    • 0036219575 scopus 로고    scopus 로고
    • Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid
    • Dawson MI, Zhang XK. Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid. Curr Med Chem 2002;9:623-37.
    • (2002) Curr Med Chem , vol.9 , pp. 623-637
    • Dawson, M.I.1    Zhang, X.K.2
  • 3
    • 34247526984 scopus 로고    scopus 로고
    • Triterpenoids and rexinoids as multi-functional agents for the prevention and treatment of cancer
    • Liby KT, Yore MM, Sporn MB. Triterpenoids and rexinoids as multi-functional agents for the prevention and treatment of cancer. Nat Rev Cancer 2007;7:357-69.
    • (2007) Nat Rev Cancer , vol.7 , pp. 357-369
    • Liby, K.T.1    Yore, M.M.2    Sporn, M.B.3
  • 4
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell 1995;83:841-50.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 5
    • 0037102446 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium
    • Huang J, Powell WC, Khodavirdi AC, Wu J, Makita T, Cardiff RD, et al. Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium. Cancer Res 2002;62:4812-9.
    • (2002) Cancer Res , vol.62 , pp. 4812-4819
    • Huang, J.1    Powell, W.C.2    Khodavirdi, A.C.3    Wu, J.4    Makita, T.5    Cardiff, R.D.6
  • 6
    • 0034609819 scopus 로고    scopus 로고
    • Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis
    • Li M, Indra AK, Warot X, Brocard J, Messaddeq N, Kato S, et al. Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis. Nature 2000;407:633-6.
    • (2000) Nature , vol.407 , pp. 633-636
    • Li, M.1    Indra, A.K.2    Warot, X.3    Brocard, J.4    Messaddeq, N.5    Kato, S.6
  • 7
    • 0035886844 scopus 로고    scopus 로고
    • Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma
    • Matsushima-Nishiwaki R, Okuno M, Adachi S, Sano T, Akita K, Moriwaki H, et al. Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma. Cancer Res 2001;61:7675-82.
    • (2001) Cancer Res , vol.61 , pp. 7675-7682
    • Matsushima-Nishiwaki, R.1    Okuno, M.2    Adachi, S.3    Sano, T.4    Akita, K.5    Moriwaki, H.6
  • 8
    • 35548999307 scopus 로고    scopus 로고
    • Synergistic effects of RXR{alpha} and PPAR gamma ligands to inhibit growth in human colon cancer cells-phosphorylated RXR{alpha} is a critical target for colon cancer management1
    • Yamazaki K, Shimizu M, Okuno M, Matsushima-Nishiwaki R, Kanemura N, Araki H, et al. Synergistic effects of RXR{alpha} and PPAR gamma ligands to inhibit growth in human colon cancer cells-phosphorylated RXR{alpha} is a critical target for colon cancer management1. Gut 2007;56:1557-63.
    • (2007) Gut , vol.56 , pp. 1557-1563
    • Yamazaki, K.1    Shimizu, M.2    Okuno, M.3    Matsushima-Nishiwaki, R.4    Kanemura, N.5    Araki, H.6
  • 9
    • 0033639286 scopus 로고    scopus 로고
    • Retinoic acid receptor and retinoid X receptor in ductal carcinoma in situ and intraductal proliferative lesions of the human breast
    • Ariga N, Moriya T, Suzuki T, Kimura M, Ohuchi N, Sasano H. Retinoic acid receptor and retinoid X receptor in ductal carcinoma in situ and intraductal proliferative lesions of the human breast. Jpn J Cancer Res 2000;91:1169-76.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1169-1176
    • Ariga, N.1    Moriya, T.2    Suzuki, T.3    Kimura, M.4    Ohuchi, N.5    Sasano, H.6
  • 10
    • 0032897401 scopus 로고    scopus 로고
    • Expression of nuclear retinoid receptors in normal, premalignant and malignant gastric tissues determined by in situ hybridization
    • Jiang SY, Shen SR, Shyu RY, Yu JC, Harn HJ, Yeh MY, et al. Expression of nuclear retinoid receptors in normal, premalignant and malignant gastric tissues determined by in situ hybridization. Br J Cancer 1999;80:206-14.
    • (1999) Br J Cancer , vol.80 , pp. 206-214
    • Jiang, S.Y.1    Shen, S.R.2    Shyu, R.Y.3    Yu, J.C.4    Harn, H.J.5    Yeh, M.Y.6
  • 11
    • 0033986007 scopus 로고    scopus 로고
    • Differential expression of nuclear retinoid receptors in normal and malignant prostates
    • Lotan Y, Xu XC, Shalev M, Lotan R, Williams R, Wheeler TM, et al. Differential expression of nuclear retinoid receptors in normal and malignant prostates. J Clin Oncol 2000;18:116-21.
    • (2000) J Clin Oncol , vol.18 , pp. 116-121
    • Lotan, Y.1    Xu, X.C.2    Shalev, M.3    Lotan, R.4    Williams, R.5    Wheeler, T.M.6
  • 14
    • 0141976407 scopus 로고    scopus 로고
    • Aberration in the expression of the retinoid receptor, RXRalpha, in prostate cancer
    • Zhong C, Yang S, Huang J, Cohen MB, Roy-Burman P. Aberration in the expression of the retinoid receptor, RXRalpha, in prostate cancer. Cancer Biol Ther 2003;2:179-84.
    • (2003) Cancer Biol Ther , vol.2 , pp. 179-184
    • Zhong, C.1    Yang, S.2    Huang, J.3    Cohen, M.B.4    Roy-Burman, P.5
  • 15
    • 0037334906 scopus 로고    scopus 로고
    • Endocrine regulation of mitochondrial activity:Involvement of truncated RXRalpha and c-Erb Aalpha1 proteins
    • Casas F, Daury L, Grandemange S, Busson M, Seyer P, Hatier R, et al. Endocrine regulation of mitochondrial activity:involvement of truncated RXRalpha and c-Erb Aalpha1 proteins. FASEB J 2003;17:426-36.
    • (2003) FASEB J , vol.17 , pp. 426-436
    • Casas, F.1    Daury, L.2    Grandemange, S.3    Busson, M.4    Seyer, P.5    Hatier, R.6
  • 16
    • 0032509203 scopus 로고    scopus 로고
    • Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action
    • Nagaya T, Murata Y, Yamaguchi S, Nomura Y, Ohmori S, Fujieda M, et al. Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action. J Biol Chem 1998;273:33166-73.
    • (1998) J Biol Chem , vol.273 , pp. 33166-33173
    • Nagaya, T.1    Murata, Y.2    Yamaguchi, S.3    Nomura, Y.4    Ohmori, S.5    Fujieda, M.6
  • 17
    • 0036256723 scopus 로고    scopus 로고
    • Degradation of RXRs influences sensitivity of rat osteosarcoma cells to the antiproliferative effects of calcitriol
    • Prufer K, Schroder C, Hegyi K, Barsony J. Degradation of RXRs influences sensitivity of rat osteosarcoma cells to the antiproliferative effects of calcitriol. Mol Endocrinol 2002;16:961-76.
    • (2002) Mol Endocrinol , vol.16 , pp. 961-976
    • Prufer, K.1    Schroder, C.2    Hegyi, K.3    Barsony, J.4
  • 19
    • 34347396203 scopus 로고    scopus 로고
    • Recruitment of RXR by homotetrameric RARalpha fusion proteins is essential for transformation
    • Zeisig BB, Kwok C, Zelent A, Shankaranarayanan P, Gronemeyer H, Dong S, et al. Recruitment of RXR by homotetrameric RARalpha fusion proteins is essential for transformation. Cancer Cell 2007;12:36-51.
    • (2007) Cancer Cell , vol.12 , pp. 36-51
    • Zeisig, B.B.1    Kwok, C.2    Zelent, A.3    Shankaranarayanan, P.4    Gronemeyer, H.5    Dong, S.6
  • 21
    • 7644221712 scopus 로고    scopus 로고
    • Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting
    • Cao X, Liu W, Lin F, Li H, Kolluri SK, Lin B, et al. Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting. Mol Cell Biol 2004;24:9705-25.
    • (2004) Mol Cell Biol , vol.24 , pp. 9705-9725
    • Cao, X.1    Liu, W.2    Lin, F.3    Li, H.4    Kolluri, S.K.5    Lin, B.6
  • 22
    • 18144387309 scopus 로고    scopus 로고
    • Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation
    • Ghose R, ZimmermanTL, Thevananther S, Karpen SJ. Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: a novel mechanism for reduced hepatic gene expression in inflammation. Nucl Recept 2004;2:4.
    • (2004) Nucl Recept , vol.2 , pp. 4
    • Ghose, R.1    Zimmerman, T.L.2    Thevananther, S.3    Karpen, S.J.4
  • 24
    • 33744957050 scopus 로고    scopus 로고
    • Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260
    • Zimmerman TL, Thevananther S, Ghose R, Burns AR, Karpen SJ. Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260. J Biol Chem 2006;281:15434-40.
    • (2006) J Biol Chem , vol.281 , pp. 15434-15440
    • Zimmerman, T.L.1    Thevananther, S.2    Ghose, R.3    Burns, A.R.4    Karpen, S.J.5
  • 25
    • 0344132620 scopus 로고    scopus 로고
    • Cellular and subcellular localization of six retinoid receptors in rat testis during postnatal development: Identification of potential heterodimeric receptors
    • Dufour JM, Kim KH. Cellular and subcellular localization of six retinoid receptors in rat testis during postnatal development: identification of potential heterodimeric receptors. Biol Reprod 1999;61:1300-8.
    • (1999) Biol Reprod , vol.61 , pp. 1300-1308
    • Dufour, J.M.1    Kim, K.H.2
  • 26
    • 0035004021 scopus 로고    scopus 로고
    • Changes in expression and subcellular localization of nuclear retinoic acid receptors in human endometrial epithelium during the menstrual cycle
    • Fukunaka K, Saito T, Wataba K, Ashihara K, Ito E, Kudo R. Changes in expression and subcellular localization of nuclear retinoic acid receptors in human endometrial epithelium during the menstrual cycle. Mol Hum Reprod 2001;7:437-46.
    • (2001) Mol Hum Reprod , vol.7 , pp. 437-446
    • Fukunaka, K.1    Saito, T.2    Wataba, K.3    Ashihara, K.4    Ito, E.5    Kudo, R.6
  • 27
    • 0034682890 scopus 로고    scopus 로고
    • Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
    • Li H, Kolluri SK, Gu J, Dawson MI, Cao X, Hobbs PD, et al. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science 2000;289:1159-64.
    • (2000) Science , vol.289 , pp. 1159-1164
    • Li, H.1    Kolluri, S.K.2    Gu, J.3    Dawson, M.I.4    Cao, X.5    Hobbs, P.D.6
  • 28
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
    • Lin B, Kolluri S, Lin F, Liu W, Han YH, Cao X, et al. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 2004;116:527-40.
    • (2004) Cell , vol.116 , pp. 527-540
    • Lin, B.1    Kolluri, S.2    Lin, F.3    Liu, W.4    Han, Y.H.5    Cao, X.6
  • 29
    • 77953283014 scopus 로고    scopus 로고
    • NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling
    • Zhou H, Liu W, Su Y, Wei Z, Liu J, Kolluri SK, et al. NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell 2010;17:560-73.
    • (2010) Cancer Cell , vol.17 , pp. 560-573
    • Zhou, H.1    Liu, W.2    Su, Y.3    Wei, Z.4    Liu, J.5    Kolluri, S.K.6
  • 30
    • 26044467360 scopus 로고    scopus 로고
    • Xanthone derivatives: New insights in biological activities
    • Pinto MM, Sousa ME, Nascimento MS. Xanthone derivatives: new insights in biological activities. Curr Med Chem 2005;12:2517-38.
    • (2005) Curr Med Chem , vol.12 , pp. 2517-2538
    • Pinto, M.M.1    Sousa, M.E.2    Nascimento, M.S.3
  • 31
    • 85047686294 scopus 로고    scopus 로고
    • Recent cancer drug development with xanthone structures
    • Na Y. Recent cancer drug development with xanthone structures. J Pharm Pharmacol 2009;61:707-12.
    • (2009) J Pharm Pharmacol , vol.61 , pp. 707-712
    • Na, Y.1
  • 33
    • 41649101808 scopus 로고    scopus 로고
    • Anti-cancer effects of xanthones from pericarps of mangosteen
    • Akao Y, Nakagawa Y, Iinuma M, Nozawa Y. Anti-cancer effects of xanthones from pericarps of mangosteen. Int J Mol Sci 2008;9:355-70.
    • (2008) Int J Mol Sci , vol.9 , pp. 355-370
    • Akao, Y.1    Nakagawa, Y.2    Iinuma, M.3    Nozawa, Y.4
  • 34
    • 79551473594 scopus 로고    scopus 로고
    • Xanthone and benzophenone glycosides from the stems of Cratoxylum formosum ssp. pruniflorum
    • Tokyo
    • Duan YH, Dai Y, Wang GH, Chen HF, Gao H, Chen JB, et al. Xanthone and benzophenone glycosides from the stems of Cratoxylum formosum ssp. pruniflorum. Chem Pharm Bull (Tokyo) 2011;59:231-4.
    • (2011) Chem Pharm Bull , vol.59 , pp. 231-234
    • Duan, Y.H.1    Dai, Y.2    Wang, G.H.3    Chen, H.F.4    Gao, H.5    Chen, J.B.6
  • 35
    • 77954934953 scopus 로고    scopus 로고
    • Bioactive xanthones from the stems of Cratoxylum formosum ssp. pruniflorum
    • Duan YH, Dai Y, Wang GH, Zhang X, Chen HF, Chen JB, et al. Bioactive xanthones from the stems of Cratoxylum formosum ssp. pruniflorum. J Nat Prod 2010;73:1283-7.
    • (2010) J Nat Prod , vol.73 , pp. 1283-1287
    • Duan, Y.H.1    Dai, Y.2    Wang, G.H.3    Zhang, X.4    Chen, H.F.5    Chen, J.B.6
  • 39
    • 73349084304 scopus 로고    scopus 로고
    • The effect of antagonists on the conformational exchange of the retinoid X receptor alpha ligand-binding domain
    • Lu J, Dawson MI, HuQY, Xia Z, Dambacher JD, Ye M, et al. The effect of antagonists on the conformational exchange of the retinoid X receptor alpha ligand-binding domain. Magn Reson Chem 2009;47:1071-80.
    • (2009) Magn Reson Chem , vol.47 , pp. 1071-1080
    • Lu, J.1    Dawson, M.I.2    Hu, Q.Y.3    Xia, Z.4    Dambacher, J.D.5    Ye, M.6
  • 41
    • 78649771898 scopus 로고    scopus 로고
    • The "Phantom Effect" of the Rexinoid LG100754: Structural and functional insights
    • Sato Y, Ramalanjaona N, Huet T, Potier N, Osz J, Antony P, et al. The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights. PLoS ONE 2010;5:e15119.
    • (2010) PLoS ONE , vol.5
    • Sato, Y.1    Ramalanjaona, N.2    Huet, T.3    Potier, N.4    Osz, J.5    Antony, P.6
  • 42
    • 0036251738 scopus 로고    scopus 로고
    • Molecular recognition of agonist ligands by RXRs
    • Egea PF, Mitschler A, Moras D. Molecular recognition of agonist ligands by RXRs. Mol Endocrinol 2002;16:987-97.
    • (2002) Mol Endocrinol , vol.16 , pp. 987-997
    • Egea, P.F.1    Mitschler, A.2    Moras, D.3
  • 43
    • 0034213831 scopus 로고    scopus 로고
    • Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid
    • Egea PF, Mitschler A, Rochel N, Ruff M, Chambon P, Moras D. Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid. EMBO J 2000;19:2592-601.
    • (2000) EMBO J , vol.19 , pp. 2592-2601
    • Egea, P.F.1    Mitschler, A.2    Rochel, N.3    Ruff, M.4    Chambon, P.5    Moras, D.6
  • 44
    • 0034521981 scopus 로고    scopus 로고
    • Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models
    • Kollman PA, Massova I, Reyes C, Kuhn B, Huo S, Chong L, et al. Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models. Acc Chem Res 2000;33:889-97.
    • (2000) Acc Chem Res , vol.33 , pp. 889-897
    • Kollman, P.A.1    Massova, I.2    Reyes, C.3    Kuhn, B.4    Huo, S.5    Chong, L.6
  • 45
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase i inhibitors: Camptothecins and beyond
    • Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 2006;6:789-802.
    • (2006) Nat Rev Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 46
    • 52949131927 scopus 로고    scopus 로고
    • A short Nur77-derived peptide converts Bcl-2 from a protector to a killer
    • Kolluri SK, Zhu X, Zhou X, Lin B, Chen Y, Sun K, et al. A short Nur77-derived peptide converts Bcl-2 from a protector to a killer. Cancer Cell 2008;14:285-98.
    • (2008) Cancer Cell , vol.14 , pp. 285-298
    • Kolluri, S.K.1    Zhu, X.2    Zhou, X.3    Lin, B.4    Chen, Y.5    Sun, K.6
  • 47
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer 2009;9:361-71.
    • (2009) Nat Rev Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 48
    • 38449100291 scopus 로고    scopus 로고
    • TNF and cancer: The two sides of the coin
    • Mocellin S, Nitti D. TNF and cancer: the two sides of the coin. Front Biosci 2008;13:2774-83.
    • (2008) Front Biosci , vol.13 , pp. 2774-2783
    • Mocellin, S.1    Nitti, D.2
  • 49
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: Triumphs and trials
    • Corson TW, Crews CM. Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell 2007;130:769-74.
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1    Crews, C.M.2
  • 50
    • 0019303385 scopus 로고
    • Psorospermin, a new anti-leukemic xanthone from Psorospermum febrifugum
    • Kupchan SM, Streelman DR, Sneden AT. Psorospermin, a new anti-leukemic xanthone from Psorospermum febrifugum. J Nat Prod 1980;43:296-301.
    • (1980) J Nat Prod , vol.43 , pp. 296-301
    • Kupchan, S.M.1    Streelman, D.R.2    Sneden, A.T.3
  • 51
    • 0038575250 scopus 로고    scopus 로고
    • Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent
    • Jameson MB, Thompson PI, Baguley BC, Evans BD, Harvey VJ, Porter DJ, et al. Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent. Br J Cancer 2003;88:1844-50.
    • (2003) Br J Cancer , vol.88 , pp. 1844-1850
    • Jameson, M.B.1    Thompson, P.I.2    Baguley, B.C.3    Evans, B.D.4    Harvey, V.J.5    Porter, D.J.6
  • 52
    • 0042422298 scopus 로고    scopus 로고
    • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines
    • Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod 2003;66:1124-7.
    • (2003) J Nat Prod , vol.66 , pp. 1124-1127
    • Matsumoto, K.1    Akao, Y.2    Kobayashi, E.3    Ohguchi, K.4    Ito, T.5    Tanaka, T.6
  • 54
    • 79952006933 scopus 로고    scopus 로고
    • Structure basis of bigelovin as a selectiveRXRagonist with a distinct binding mode
    • Zhang H, Li L, Chen L, Hu L, Jiang H, Shen X. Structure basis of bigelovin as a selectiveRXRagonist with a distinct binding mode. J Mol Biol 2011;407:13-20.
    • (2011) J Mol Biol , vol.407 , pp. 13-20
    • Zhang, H.1    Li, L.2    Chen, L.3    Hu, L.4    Jiang, H.5    Shen, X.6
  • 55
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999;401:82-5.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 56
    • 49049106608 scopus 로고    scopus 로고
    • Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity
    • Pincheira R, Castro AF, Ozes ON, Idumalla PS, Donner DB. Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity. J Immunol 2008;181:1288-98.
    • (2008) J Immunol , vol.181 , pp. 1288-1298
    • Pincheira, R.1    Castro, A.F.2    Ozes, O.N.3    Idumalla, P.S.4    Donner, D.B.5
  • 57
    • 38449111027 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) biology and cell death
    • Bertazza L, Mocellin S. Tumor necrosis factor (TNF) biology and cell death. Front Biosci 2008;13:2736-43.
    • (2008) Front Biosci , vol.13 , pp. 2736-2743
    • Bertazza, L.1    Mocellin, S.2
  • 58
    • 33645782015 scopus 로고    scopus 로고
    • TNF-alpha in cancer treatment: Molecular insights, antitumor effects, and clinical utility
    • van Horssen R, Ten Hagen TL, Eggermont AM. TNF-alpha in cancer treatment: molecular insights, antitumor effects, and clinical utility. Oncologist 2006;11:397-408.
    • (2006) Oncologist , vol.11 , pp. 397-408
    • Van Horssen, R.1    Ten Hagen, T.L.2    Eggermont, A.M.3
  • 59
    • 55149097289 scopus 로고    scopus 로고
    • Tumor necrosis factor and cancer, buddies or foes?
    • Wang X, Lin Y. Tumor necrosis factor and cancer, buddies or foes? Acta Pharmacol Sin 2008;29:1275-88.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 1275-1288
    • Wang, X.1    Lin, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.