-
1
-
-
25444495618
-
Rexinoid-triggered differentiation and tumours selective apoptosis of AML by protein kinase-A-mediated de-subordination of RXR
-
Altucci L., Rossin A., Hirsch O., Nebbioso A., Vitoux D., Wilhelm E., Guidez F., Schiavone E.M., Grimwade D., Zelent A., et al. Rexinoid-triggered differentiation and tumours selective apoptosis of AML by protein kinase-A-mediated de-subordination of RXR. Cancer Res. 65 (2005) 8754-8765
-
(2005)
Cancer Res.
, vol.65
, pp. 8754-8765
-
-
Altucci, L.1
Rossin, A.2
Hirsch, O.3
Nebbioso, A.4
Vitoux, D.5
Wilhelm, E.6
Guidez, F.7
Schiavone, E.M.8
Grimwade, D.9
Zelent, A.10
-
2
-
-
13344260002
-
Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RAR alpha-mediated increase of type II transglutaminase
-
Benedetti L., Grignani F., Scicchitano B.M., Jetten A.M., Diverio D., Lo Coco F., Avvisati G., Gambarcoti-Passerini C., Adamo S., Levin A.A., et al. Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RAR alpha-mediated increase of type II transglutaminase. Blood 87 (1996) 1939-1950
-
(1996)
Blood
, vol.87
, pp. 1939-1950
-
-
Benedetti, L.1
Grignani, F.2
Scicchitano, B.M.3
Jetten, A.M.4
Diverio, D.5
Lo Coco, F.6
Avvisati, G.7
Gambarcoti-Passerini, C.8
Adamo, S.9
Levin, A.A.10
-
3
-
-
0033572682
-
RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
-
Benoit G., Altucci L., Flexor M., Ruchaud S., Lillehaug J., Raffelsberger W., Gronemeyer H., and Lanotte M. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18 (1999) 7011-7018
-
(1999)
EMBO J.
, vol.18
, pp. 7011-7018
-
-
Benoit, G.1
Altucci, L.2
Flexor, M.3
Ruchaud, S.4
Lillehaug, J.5
Raffelsberger, W.6
Gronemeyer, H.7
Lanotte, M.8
-
4
-
-
0030615230
-
A PML RAR alpha transgene initiates murine acute promyelocytic leukemia
-
Brown D., Kogan S., Lagasse E., Weissman I., Alcalay M., Pelicci P.G., Atwater S., and Bishop J.M. A PML RAR alpha transgene initiates murine acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 94 (1997) 2551-2556
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2551-2556
-
-
Brown, D.1
Kogan, S.2
Lagasse, E.3
Weissman, I.4
Alcalay, M.5
Pelicci, P.G.6
Atwater, S.7
Bishop, J.M.8
-
5
-
-
33744798752
-
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes
-
Calleja C., Messaddeq N., Chapellier B., Yang H., Krezel W., Li M., Metzger D., Mascrez B., Ohta K., Kagechika H., et al. Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes. Genes Dev. 20 (2006) 1525-1538
-
(2006)
Genes Dev.
, vol.20
, pp. 1525-1538
-
-
Calleja, C.1
Messaddeq, N.2
Chapellier, B.3
Yang, H.4
Krezel, W.5
Li, M.6
Metzger, D.7
Mascrez, B.8
Ohta, K.9
Kagechika, H.10
-
6
-
-
33750089739
-
Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1
-
Choi S.J., Chung S.S., Rho E.J., Lee H.W., Lee M.H., Choi H.S., Seol J.H., Baek S.H., Bang O.S., and Chung C.H. Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. J. Biol. Chem. 281 (2006) 30669-30677
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30669-30677
-
-
Choi, S.J.1
Chung, S.S.2
Rho, E.J.3
Lee, H.W.4
Lee, M.H.5
Choi, H.S.6
Seol, J.H.7
Baek, S.H.8
Bang, O.S.9
Chung, C.H.10
-
7
-
-
0025098239
-
Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene
-
de Thé H., Vivanco-Ruiz M.M., Tiollais P., Stunnenberg H., and Dejean A. Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene. Nature 343 (1990) 177-180
-
(1990)
Nature
, vol.343
, pp. 177-180
-
-
de Thé, H.1
Vivanco-Ruiz, M.M.2
Tiollais, P.3
Stunnenberg, H.4
Dejean, A.5
-
8
-
-
0025875679
-
The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
-
de Thé H., Lavau C., Marchio A., Chomienne C., Degos L., and Dejean A. The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66 (1991) 675-684
-
(1991)
Cell
, vol.66
, pp. 675-684
-
-
de Thé, H.1
Lavau, C.2
Marchio, A.3
Chomienne, C.4
Degos, L.5
Dejean, A.6
-
9
-
-
0033566289
-
Overexpression of wild-type retinoic acid receptor alpha (RAR alpha) recapitulates retinoic acid-sensitive transformation of primary myeloid progenitors by acute promyelocytic leukemia RAR alpha-fusion genes
-
Du C., Redner R.L., Cooke M.P., and Lavau C. Overexpression of wild-type retinoic acid receptor alpha (RAR alpha) recapitulates retinoic acid-sensitive transformation of primary myeloid progenitors by acute promyelocytic leukemia RAR alpha-fusion genes. Blood 94 (1999) 793-802
-
(1999)
Blood
, vol.94
, pp. 793-802
-
-
Du, C.1
Redner, R.L.2
Cooke, M.P.3
Lavau, C.4
-
10
-
-
0033034749
-
SUMO-1 modification of the acute promyelocytic leukaemia protein PML: Implications for nuclear localisation
-
Duprez E., Saurin A.J., Desterro J.M., Lallemand-Breitenbach V., Howe K., Boddy M.N., Solomon E., de Thé H., Hay R.T., and Freemont P.S. SUMO-1 modification of the acute promyelocytic leukaemia protein PML: Implications for nuclear localisation. J. Cell Sci. 112 (1999) 381-393
-
(1999)
J. Cell Sci.
, vol.112
, pp. 381-393
-
-
Duprez, E.1
Saurin, A.J.2
Desterro, J.M.3
Lallemand-Breitenbach, V.4
Howe, K.5
Boddy, M.N.6
Solomon, E.7
de Thé, H.8
Hay, R.T.9
Freemont, P.S.10
-
11
-
-
0037050017
-
Co-regulator recruitment and the mechanism of retinoic acid receptor synergy
-
Germain P., Iyer J., Zechel C., and Gronemeyer H. Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature 415 (2002) 187-192
-
(2002)
Nature
, vol.415
, pp. 187-192
-
-
Germain, P.1
Iyer, J.2
Zechel, C.3
Gronemeyer, H.4
-
12
-
-
0141706670
-
The AF-1 and AF-2 domains of RAR gamma 2 and RXR alpha cooperate for triggering the transactivation and the degradation of RAR gamma 2/RXR alpha heterodimers
-
Gianni M., Tarrade A., Nigro E.A., Garattini E., and Rochette-Egly C. The AF-1 and AF-2 domains of RAR gamma 2 and RXR alpha cooperate for triggering the transactivation and the degradation of RAR gamma 2/RXR alpha heterodimers. J. Biol. Chem. 278 (2003) 34458-34466
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34458-34466
-
-
Gianni, M.1
Tarrade, A.2
Nigro, E.A.3
Garattini, E.4
Rochette-Egly, C.5
-
13
-
-
0027320110
-
The acute promyelocytic leukemia specific PML/RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
-
Grignani F., Ferrucci P., Testa U., Talamo G., Fagioli M., Alcalay M., Mencarelli A., Grignani F., Peschle C., Nicoletti I., and Pelicci P. The acute promyelocytic leukemia specific PML/RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell 74 (1993) 423-431
-
(1993)
Cell
, vol.74
, pp. 423-431
-
-
Grignani, F.1
Ferrucci, P.2
Testa, U.3
Talamo, G.4
Fagioli, M.5
Alcalay, M.6
Mencarelli, A.7
Grignani, F.8
Peschle, C.9
Nicoletti, I.10
Pelicci, P.11
-
14
-
-
17144458786
-
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
-
Grignani F., de Matteis S., Nervi C., Tomassoni L., Gelmetti V., Cioce M., Fanelli M., Ruthardt M., Ferrara F.F., Zamir I., et al. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature 391 (1998) 815-818
-
(1998)
Nature
, vol.391
, pp. 815-818
-
-
Grignani, F.1
de Matteis, S.2
Nervi, C.3
Tomassoni, L.4
Gelmetti, V.5
Cioce, M.6
Fanelli, M.7
Ruthardt, M.8
Ferrara, F.F.9
Zamir, I.10
-
15
-
-
0037131973
-
In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia
-
Guillemin M.C., Raffoux E., Vitoux D., Kogan S., Soilihi H., Lallemand-Breitenbach V., Zhu J., Janin A., Daniel M.T., Gourmel B., et al. In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia. J. Exp. Med. 196 (2002) 1373-1380
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1373-1380
-
-
Guillemin, M.C.1
Raffoux, E.2
Vitoux, D.3
Kogan, S.4
Soilihi, H.5
Lallemand-Breitenbach, V.6
Zhu, J.7
Janin, A.8
Daniel, M.T.9
Gourmel, B.10
-
16
-
-
0141593653
-
A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis
-
Hansen L.A., Brown D., Virador V., Tanaka T., Andreola F., Strain K., Dancheck B., Riley R., Arbeit J.M., De Luca L.M., et al. A PMLRARA transgene results in a retinoid-deficient phenotype associated with enhanced susceptibility to skin tumorigenesis. Cancer Res. 63 (2003) 5257-5265
-
(2003)
Cancer Res.
, vol.63
, pp. 5257-5265
-
-
Hansen, L.A.1
Brown, D.2
Virador, V.3
Tanaka, T.4
Andreola, F.5
Strain, K.6
Dancheck, B.7
Riley, R.8
Arbeit, J.M.9
De Luca, L.M.10
-
17
-
-
15944406765
-
SUMO: A history of modification
-
Hay R.T. SUMO: A history of modification. Mol. Cell 18 (2005) 1-12
-
(2005)
Mol. Cell
, vol.18
, pp. 1-12
-
-
Hay, R.T.1
-
18
-
-
0344305376
-
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
-
Huang T.T., Wuerzberger-Davis S.M., Wu Z.H., and Miyamoto S. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115 (2003) 565-576
-
(2003)
Cell
, vol.115
, pp. 565-576
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Wu, Z.H.3
Miyamoto, S.4
-
19
-
-
0029081592
-
Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways
-
Jansen J.H., Mahfoudi A., Rambaud S., Lavau C., Wahli W., and Dejean A. Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways. Proc. Natl. Acad. Sci. USA 92 (1995) 7401-7405
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7401-7405
-
-
Jansen, J.H.1
Mahfoudi, A.2
Rambaud, S.3
Lavau, C.4
Wahli, W.5
Dejean, A.6
-
20
-
-
0032947848
-
Retinoid X receptor (RXR) agonist-induced activation of dominant-negative RXR-retinoic acid receptor alpha 403 heterodimers is developmentally regulated during myeloid differentiation
-
Johnson B.S., Chandraratna R.A.S., Heyman R.A., Allegretto E.A., Mueller L., and Collins S.J. Retinoid X receptor (RXR) agonist-induced activation of dominant-negative RXR-retinoic acid receptor alpha 403 heterodimers is developmentally regulated during myeloid differentiation. Mol. Cell. Biol. 19 (1999) 3372-3382
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3372-3382
-
-
Johnson, B.S.1
Chandraratna, R.A.S.2
Heyman, R.A.3
Allegretto, E.A.4
Mueller, L.5
Collins, S.J.6
-
21
-
-
13844299891
-
PML/RARA-RXR oligomers mediate retinoid- and rexinoid-/cAMP in APL cell differentiation
-
Kamashev D.E., Vitoux D., and De Thé H. PML/RARA-RXR oligomers mediate retinoid- and rexinoid-/cAMP in APL cell differentiation. J. Exp. Med. 199 (2004) 1-13
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1-13
-
-
Kamashev, D.E.1
Vitoux, D.2
De Thé, H.3
-
22
-
-
0032500634
-
Identification of three major sentrinization sites in PML
-
Kamitani T., Kito K., Nguyen H.P., Wada H., Fukuda-Kamitani T., and Yeh E.T.H. Identification of three major sentrinization sites in PML. J. Biol. Chem. 41 (1998) 26675-26682
-
(1998)
J. Biol. Chem.
, vol.41
, pp. 26675-26682
-
-
Kamitani, T.1
Kito, K.2
Nguyen, H.P.3
Wada, H.4
Fukuda-Kamitani, T.5
Yeh, E.T.H.6
-
23
-
-
0026583943
-
Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins
-
Kastner P., Perez A., Lutz Y., Rochette-Egly C., Gaub M.-P., Durand B., Lanotte M., Berger R., and Chambon P. Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): Structural similarities with a new family of oncoproteins. EMBO J. 11 (1992) 629-642
-
(1992)
EMBO J.
, vol.11
, pp. 629-642
-
-
Kastner, P.1
Perez, A.2
Lutz, Y.3
Rochette-Egly, C.4
Gaub, M.-P.5
Durand, B.6
Lanotte, M.7
Berger, R.8
Chambon, P.9
-
24
-
-
0029584593
-
Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
-
Kastner P., Mark M., and Chambon P. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?. Cell 83 (1995) 859-869
-
(1995)
Cell
, vol.83
, pp. 859-869
-
-
Kastner, P.1
Mark, M.2
Chambon, P.3
-
25
-
-
0036660179
-
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice
-
Kogan S.C., Ward J.M., Anver M.R., Berman J.J., Brayton C., Cardiff R.D., Carter J.S., de Coronado S., Downing J.R., Fredrickson T.N., et al. Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood 100 (2002) 238-245
-
(2002)
Blood
, vol.100
, pp. 238-245
-
-
Kogan, S.C.1
Ward, J.M.2
Anver, M.R.3
Berman, J.J.4
Brayton, C.5
Cardiff, R.D.6
Carter, J.S.7
de Coronado, S.8
Downing, J.R.9
Fredrickson, T.N.10
-
26
-
-
1642399848
-
Allostery and coupled sequence variation in nuclear hormone receptors
-
Kuriyan J. Allostery and coupled sequence variation in nuclear hormone receptors. Cell 116 (2004) 354-356
-
(2004)
Cell
, vol.116
, pp. 354-356
-
-
Kuriyan, J.1
-
27
-
-
32044463370
-
Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells
-
Kwok C., Zeisig B.B., Dong S., and So C.W. Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells. Cancer Cell 9 (2006) 95-108
-
(2006)
Cancer Cell
, vol.9
, pp. 95-108
-
-
Kwok, C.1
Zeisig, B.B.2
Dong, S.3
So, C.W.4
-
28
-
-
0033526012
-
Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia
-
Lallemand-Breitenbach V., Guillemin M.-C., Janin A., Daniel M.-T., Degos L., Kogan S.C., Bishop J.M., and de Thé H. Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia. J. Exp. Med. 189 (1999) 1043-1052
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1043-1052
-
-
Lallemand-Breitenbach, V.1
Guillemin, M.-C.2
Janin, A.3
Daniel, M.-T.4
Degos, L.5
Kogan, S.C.6
Bishop, J.M.7
de Thé, H.8
-
29
-
-
0035908032
-
Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As(2)O(3)-induced PML or PML/retinoic acid receptor alpha degradation
-
Lallemand-Breitenbach V., Zhu J., Puvion F., Koken M., Honore N., Doubeikovsky A., Duprez E., Pandolfi P.P., Puvion E., Freemont P., and de Thé H. Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As(2)O(3)-induced PML or PML/retinoic acid receptor alpha degradation. J. Exp. Med. 193 (2001) 1361-1372
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1361-1372
-
-
Lallemand-Breitenbach, V.1
Zhu, J.2
Puvion, F.3
Koken, M.4
Honore, N.5
Doubeikovsky, A.6
Duprez, E.7
Pandolfi, P.P.8
Puvion, E.9
Freemont, P.10
de Thé, H.11
-
30
-
-
0345708448
-
Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice
-
Lane A.A., and Ley T.J. Neutrophil elastase cleaves PML-RARalpha and is important for the development of acute promyelocytic leukemia in mice. Cell 115 (2003) 305-318
-
(2003)
Cell
, vol.115
, pp. 305-318
-
-
Lane, A.A.1
Ley, T.J.2
-
31
-
-
0029995024
-
Retroviral vectors for the transduction of the PML-RARalpha fusion product of acute promyelocytic leukemia
-
Lavau C., Heard J.M., Danos O., and Dejean A. Retroviral vectors for the transduction of the PML-RARalpha fusion product of acute promyelocytic leukemia. Exp. Hematol. 24 (1996) 544-551
-
(1996)
Exp. Hematol.
, vol.24
, pp. 544-551
-
-
Lavau, C.1
Heard, J.M.2
Danos, O.3
Dejean, A.4
-
32
-
-
0034609819
-
Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis
-
Li M., Indra A.K., Warot X., Brocard J., Messaddeq N., Kato S., Metzger D., and Chambon P. Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis. Nature 407 (2000) 633-636
-
(2000)
Nature
, vol.407
, pp. 633-636
-
-
Li, M.1
Indra, A.K.2
Warot, X.3
Brocard, J.4
Messaddeq, N.5
Kato, S.6
Metzger, D.7
Chambon, P.8
-
33
-
-
32044441026
-
Reconstructing a disease: What essential features of the retinoic acid receptor fusion oncoproteins generate acute promyelocytic leukemia?
-
Licht J.D. Reconstructing a disease: What essential features of the retinoic acid receptor fusion oncoproteins generate acute promyelocytic leukemia?. Cancer Cell 9 (2006) 73-74
-
(2006)
Cancer Cell
, vol.9
, pp. 73-74
-
-
Licht, J.D.1
-
34
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukaemia
-
Lin R.J., Nagy L., Inoue S., Shao W.L., Miller W.H., and Evans R.M. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 391 (1998) 811-814
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.L.4
Miller, W.H.5
Evans, R.M.6
-
35
-
-
0033634946
-
Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers
-
Lin R., and Evans R. Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers. Mol. Cell 5 (2000) 821-830
-
(2000)
Mol. Cell
, vol.5
, pp. 821-830
-
-
Lin, R.1
Evans, R.2
-
36
-
-
26444504134
-
Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation
-
Mann K.K., Padovani A.M., Guo Q., Colosimo A.L., Lee H.Y., Kurie J.M., and Miller Jr. W.H. Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation. J. Clin. Invest. 115 (2005) 2924-2933
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2924-2933
-
-
Mann, K.K.1
Padovani, A.M.2
Guo, Q.3
Colosimo, A.L.4
Lee, H.Y.5
Kurie, J.M.6
Miller Jr., W.H.7
-
37
-
-
33645873584
-
In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia
-
Matsushita H., Scaglioni P.P., Bhaumik M., Rego E.M., Cai L.F., Majid S.M., Miyachi H., Kakizuka A., Miller Jr. W.H., and Pandolfi P.P. In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia. J. Exp. Med. 203 (2006) 821-828
-
(2006)
J. Exp. Med.
, vol.203
, pp. 821-828
-
-
Matsushita, H.1
Scaglioni, P.P.2
Bhaumik, M.3
Rego, E.M.4
Cai, L.F.5
Majid, S.M.6
Miyachi, H.7
Kakizuka, A.8
Miller Jr., W.H.9
Pandolfi, P.P.10
-
38
-
-
0033638969
-
Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation
-
Minucci S., Maccarana M., Cioce M., De Luca P., Gelmetti V., Segalla S., Di Croce L., Giavara S., Matteucci C., Gobbi A., et al. Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. Mol. Cell 5 (2000) 811-820
-
(2000)
Mol. Cell
, vol.5
, pp. 811-820
-
-
Minucci, S.1
Maccarana, M.2
Cioce, M.3
De Luca, P.4
Gelmetti, V.5
Segalla, S.6
Di Croce, L.7
Giavara, S.8
Matteucci, C.9
Gobbi, A.10
-
39
-
-
0037498052
-
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
-
Muller S., Matunis M.J., and Dejean A. Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J. 17 (1998) 61-70
-
(1998)
EMBO J.
, vol.17
, pp. 61-70
-
-
Muller, S.1
Matunis, M.J.2
Dejean, A.3
-
40
-
-
0027328057
-
PML/RAR homodimers: Distinct binding properties and heteromeric interactions with RXR
-
Perez A., Kastner P., Sethi S., Lutz Y., Reibel C., and Chambon P. PML/RAR homodimers: Distinct binding properties and heteromeric interactions with RXR. EMBO J. 12 (1993) 3171-3182
-
(1993)
EMBO J.
, vol.12
, pp. 3171-3182
-
-
Perez, A.1
Kastner, P.2
Sethi, S.3
Lutz, Y.4
Reibel, C.5
Chambon, P.6
-
41
-
-
0031752849
-
A sustained increase in the endogenous level of cAMP reduces the retinoid concentration required for APL cell maturation to near physiological levels
-
Quenech'Du N., Ruchaud S., Khelef N., Guiso N., and Lanotte M. A sustained increase in the endogenous level of cAMP reduces the retinoid concentration required for APL cell maturation to near physiological levels. Leukemia 12 (1998) 1829-1833
-
(1998)
Leukemia
, vol.12
, pp. 1829-1833
-
-
Quenech'Du, N.1
Ruchaud, S.2
Khelef, N.3
Guiso, N.4
Lanotte, M.5
-
42
-
-
0029965094
-
The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells
-
Rusten L.S., Dybedal I., Blomhoff H.K., Blomhoff R., Smeland E.B., and Jacobsen S.E. The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells. Blood 87 (1996) 1728-1736
-
(1996)
Blood
, vol.87
, pp. 1728-1736
-
-
Rusten, L.S.1
Dybedal, I.2
Blomhoff, H.K.3
Blomhoff, R.4
Smeland, E.B.5
Jacobsen, S.E.6
-
43
-
-
0028941493
-
Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor
-
Saitou M., Sugai S., Tanaka T., Shimouchi K., Fuchs E., Narumiya S., and Kakizuka A. Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature 374 (1995) 159-162
-
(1995)
Nature
, vol.374
, pp. 159-162
-
-
Saitou, M.1
Sugai, S.2
Tanaka, T.3
Shimouchi, K.4
Fuchs, E.5
Narumiya, S.6
Kakizuka, A.7
-
44
-
-
28444440238
-
Leukemia: Stem cells, maturation arrest, and differentiation therapy
-
Sell S. Leukemia: Stem cells, maturation arrest, and differentiation therapy. Stem Cell Rev. 1 (2005) 197-205
-
(2005)
Stem Cell Rev.
, vol.1
, pp. 197-205
-
-
Sell, S.1
-
45
-
-
0030992905
-
A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation
-
Shao W., Benedetti L., Lamph W.W., Nervi C., and Miller W.H.J. A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation. Blood 89 (1997) 4282-4289
-
(1997)
Blood
, vol.89
, pp. 4282-4289
-
-
Shao, W.1
Benedetti, L.2
Lamph, W.W.3
Nervi, C.4
Miller, W.H.J.5
-
46
-
-
0033559654
-
Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro
-
Shiohara M., Dawson M.I., Hobbs P.D., Sawai N., Higuchi T., Koike K., Komiyama A., and Koeffler H.P. Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro. Blood 93 (1999) 2057-2066
-
(1999)
Blood
, vol.93
, pp. 2057-2066
-
-
Shiohara, M.1
Dawson, M.I.2
Hobbs, P.D.3
Sawai, N.4
Higuchi, T.5
Koike, K.6
Komiyama, A.7
Koeffler, H.P.8
-
47
-
-
12844281209
-
c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha
-
Srinivas H., Juroske D.M., Kalyankrishna S., Cody D.D., Price R.E., Xu X.C., Narayanan R., Weigel N.L., and Kurie J.M. c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha. Mol. Cell. Biol. 25 (2005) 1054-1069
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1054-1069
-
-
Srinivas, H.1
Juroske, D.M.2
Kalyankrishna, S.3
Cody, D.D.4
Price, R.E.5
Xu, X.C.6
Narayanan, R.7
Weigel, N.L.8
Kurie, J.M.9
-
48
-
-
32044471311
-
Forced retinoic acid receptor a homodimer prime mice for APL-like leukemia
-
Sternsdorf T., Phan V.T., Maunakea M.L., Ocampo C., Sohal J., Siletto A., Galimi F., Le Beau M.M., Evans R., and Kogan S. Forced retinoic acid receptor a homodimer prime mice for APL-like leukemia. Cancer Cell 9 (2006) 81-94
-
(2006)
Cancer Cell
, vol.9
, pp. 81-94
-
-
Sternsdorf, T.1
Phan, V.T.2
Maunakea, M.L.3
Ocampo, C.4
Sohal, J.5
Siletto, A.6
Galimi, F.7
Le Beau, M.M.8
Evans, R.9
Kogan, S.10
-
49
-
-
2442485843
-
The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity
-
Takano Y., Adachi S., Okuno M., Muto Y., Yoshioka T., Matsushima-Nishiwaki R., Tsurumi H., Ito K., Friedman S.L., Moriwaki H., et al. The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity. J. Biol. Chem. 279 (2004) 18926-18934
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18926-18934
-
-
Takano, Y.1
Adachi, S.2
Okuno, M.3
Muto, Y.4
Yoshioka, T.5
Matsushima-Nishiwaki, R.6
Tsurumi, H.7
Ito, K.8
Friedman, S.L.9
Moriwaki, H.10
-
50
-
-
16444375621
-
Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha
-
Tarrade A., Bastien J., Bruck N., Bauer A., Gianni M., and Rochette-Egly C. Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha. Oncogene 24 (2005) 2277-2288
-
(2005)
Oncogene
, vol.24
, pp. 2277-2288
-
-
Tarrade, A.1
Bastien, J.2
Bruck, N.3
Bauer, A.4
Gianni, M.5
Rochette-Egly, C.6
-
51
-
-
33846862464
-
Down-regulation of RXRα expression is essential for neutrophil development from granulocyte/monocyte progenitors
-
10.1182/blood-2006-04-020552 Published online October 3, 2006
-
Taschner S., Koesters C., Platzer B., Jorgl A., Ellmeier W., Benesch T., and Strobl H. Down-regulation of RXRα expression is essential for neutrophil development from granulocyte/monocyte progenitors. Blood 109 (2007) 971-979 10.1182/blood-2006-04-020552 Published online October 3, 2006
-
(2007)
Blood
, vol.109
, pp. 971-979
-
-
Taschner, S.1
Koesters, C.2
Platzer, B.3
Jorgl, A.4
Ellmeier, W.5
Benesch, T.6
Strobl, H.7
-
52
-
-
25844437172
-
Mutual interactions between the SUMO and ubiquitin systems: A plea of no contest
-
Ulrich H.D. Mutual interactions between the SUMO and ubiquitin systems: A plea of no contest. Trends Cell Biol. 15 (2005) 525-532
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 525-532
-
-
Ulrich, H.D.1
-
53
-
-
0037295721
-
Modification with SUMO. A role in transcriptional regulation
-
Verger A., Perdomo J., and Crossley M. Modification with SUMO. A role in transcriptional regulation. EMBO Rep. 4 (2003) 137-142
-
(2003)
EMBO Rep.
, vol.4
, pp. 137-142
-
-
Verger, A.1
Perdomo, J.2
Crossley, M.3
-
55
-
-
0042441182
-
High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression
-
Westervelt P., Lane A.A., Pollock J.L., Oldfather K., Holt M.S., Zimonjic D.B., Popescu N.C., DiPersio J.F., and Ley T.J. High-penetrance mouse model of acute promyelocytic leukemia with very low levels of PML-RARalpha expression. Blood 102 (2003) 1857-1865
-
(2003)
Blood
, vol.102
, pp. 1857-1865
-
-
Westervelt, P.1
Lane, A.A.2
Pollock, J.L.3
Oldfather, K.4
Holt, M.S.5
Zimonjic, D.B.6
Popescu, N.C.7
DiPersio, J.F.8
Ley, T.J.9
-
56
-
-
33745161824
-
Dimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization
-
Zhou J., Peres L., Honore N., Nasr R., Zhu J., and de Thé H. Dimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization. Proc. Natl. Acad. Sci. USA 103 (2006) 9238-9243
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9238-9243
-
-
Zhou, J.1
Peres, L.2
Honore, N.3
Nasr, R.4
Zhu, J.5
de Thé, H.6
-
57
-
-
0033592948
-
Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RAR alpha) and oncogenic RAR alpha fusion proteins
-
Zhu J., Gianni M., Kopf E., Honore N., Chelbi-Alix M., Koken M., Quignon F., Rochette-Egly C., and de Thé H. Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RAR alpha) and oncogenic RAR alpha fusion proteins. Proc. Natl. Acad. Sci. USA 96 (1999) 14807-14812
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14807-14812
-
-
Zhu, J.1
Gianni, M.2
Kopf, E.3
Honore, N.4
Chelbi-Alix, M.5
Koken, M.6
Quignon, F.7
Rochette-Egly, C.8
de Thé, H.9
-
58
-
-
13844269220
-
A sumoylation site in PML/RARA is essential for leukemic transformation
-
Zhu J., Zhou J., Peres L., Riaucoux F., Honore N., Kogan S., and de Thé H. A sumoylation site in PML/RARA is essential for leukemic transformation. Cancer Cell 7 (2005) 143-153
-
(2005)
Cancer Cell
, vol.7
, pp. 143-153
-
-
Zhu, J.1
Zhou, J.2
Peres, L.3
Riaucoux, F.4
Honore, N.5
Kogan, S.6
de Thé, H.7
-
59
-
-
33744957050
-
Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260
-
Zimmerman T.L., Thevananther S., Ghose R., Burns A.R., and Karpen S.J. Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260. J. Biol. Chem. 281 (2006) 15434-15440
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15434-15440
-
-
Zimmerman, T.L.1
Thevananther, S.2
Ghose, R.3
Burns, A.R.4
Karpen, S.J.5
|