Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages

Molecular and Cellular Biology

Volumn 32, Issue 23, 2012, Pages 4846-4860

  Ha, Soon Duck ^a   Park, Sangwook ^a   Han, Chae Young ^a   Nguyen, Marilyn L ^a   Kim, Sung Ouk ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTHRAX TOXIN; CARRIER PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; CHOLESTEROL; CRYOPYRIN; DNA; DNA METHYLTRANSFERASE 1; GLUTATHIONE; INTERLEUKIN 1BETA CONVERTING ENZYME; MLN64 PROTEIN; NLRP1B PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL LINE; CELL MEMBRANE; CELL MEMBRANE RESISTANCE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; DNA METHYLATION; ENDOSOME; ENZYME ACTIVATION; HYPERPOLARIZATION; MACROPHAGE; MEDIATOR; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; TOXIN INDUCED RESISTANCE; WILD TYPE;

ANIMALS; ANTHRAX; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; BETA-CYCLODEXTRINS; CASPASE 1; CELL DEATH; CELL LINE; CELLS, CULTURED; CHOLESTEROL; DNA METHYLATION; DOWN-REGULATION; GLUTATHIONE; MACROPHAGES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES;

MURINAE;

EID: 84871910605     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00494-12     Document Type: Article

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