Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 24, 1996, Pages 13731-13736

  Arakane, Futoshi ^a   Sugawara, Teruo ^a   Nishino, Hideaki ^a   Liu, Zhiming ^b   Holt, John A ^a   Pain, Debkumar ^a   Stocco, Douglas M ^b   Miller, Walter L ^c   Strauss III, Jerome F ^a,d  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d 778 Clinical Research Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; COMPLEMENTARY DNA; REGULATOR PROTEIN;

ADRENAL CORTEX; AMINO ACID SEQUENCE; ANIMAL CELL; CELL FRACTIONATION; CHOLESTEROL TRANSPORT; CONFERENCE PAPER; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; DELETION MUTANT; ELECTRON MICROSCOPY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; STEROIDOGENESIS;

ANIMALIA;

EID: 0030459652     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.24.13731     Document Type: Article

References (22)

1. Lin, D., Sugawara, T., Strauss, J. F., III, Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A. & Miller, W. L. (1995) Science 267, 1828-1831.
2. Stocco, D. M. & Clark, B. J. (1996) Endocr. Rev. 17, 221-244.
3. Pon, L. A., Hartigan, J. A. & Orme-Johnson, N. R. (1986) J. Biol. Chem. 261, 13309-13316.
4. Epstein, L. F. & Orme-Johnson, N. (1991) J. Biol. Chem. 266, 19739-19745.
5. Clark, B. J., Wells, J., King, S. R. & Stocco, D. M. (1994) J. Biol. Chem. 269, 28314-28322.
6. King, S. R., Ronen-Fuhrmann, T., Timberg, R., Clark, B. J., Orly, J. & Stocco, D. M. (1995) Endocrinology 136, 5165-5176.
7. Jefcoate, C. R., McNamara, B. C., Artemenko, I. & Yamazaki, T. (1992) J. Steroid Biochem. Mol. Biol. 43, 751-767.
8. Tee, M. K., Lin, D., Sugawara, T., Holt, J. A., Guigen, Y., Buckingham, B., Strauss, J. F., III, & Miller, W. L. (1995) Hum. Mol. Genet. 4, 2299-2305.
9. Gradi, A., Tang-Wai, R., McBride, H. M., Chu, L. L., Shore, G. C. & Pelletier, J. (1995) Biochim. Biophys. Acta 1258, 228-233.
10. Sugawara, T., Holt, J. A., Driscoll, D., Strauss, J. F., III, Lin, D., Miller, W. L., Patterson, D., Clancy, K. P., Hart, I. M., Clark, B. J. & Stocco, D. M. (1995) Proc. Natl. Acad. Sci. USA 92, 4778-4782.
11. Harikrishna, J. A., Black, S. M., Szkaz, G. D. & Miller, W. L. (1993) DNA Cell Biol. 12, 371-337.
12. Smith, R. M. & Jarett, L. (1993) in Handbook of Endocrine Research Techniques eds. de Pablo, F., Scanes, C. G. & Weintraub, B. D. (Academic, San Diego), pp. 227-264.
13. Toaff, M. E., Schleyer, H. & Strauss, J. F., III (1982) Endocrinology 111, 1785-1794.
14. Bose, H. S., Sugawara, T., Strauss, J. F., III, & Miller, W. L. for the International Lipoid CAH Consortium (1996) N. Engl. J. Med., in press.
15. Hendrick, J. P., Hodges, P. E. & Rosenberg, L. E. (1989) Proc. Natl. Acad. Sci. USA 86, 4056-4060.
16. Gavel, Y. & von Heijne, G. (1990) Protein Eng. 4, 33-37.
17. Fenton, W. A. (1995) Am. J. Hum. Genet. 57, 235-238.
18. Gazdar, A. F., Oie, H. K., Shackleton, C. H., Chen, T. R., Triche, T. J., Myers, C. E., Chrousos, G. P., Brennan, M. F., Stein, C. A. & La Rocca, R. V. (1990) Cancer Res. 50, 5488-5496.
19. Staels, B., Hum, D. W. & Miller, W. L. (1993) Mol. Endocrinol. 7, 423-433.
20. Rainey, W. E., Bird, I. M. & Mason, J. I. (1994) Mol. Cell. Endocrinol. 100, 45-50.
21. Papadopoulos, V. (1993) Endocr. Rev. 14, 222-240.
22. Schatz, G. & Dobberstein, B. (1996) Science 271, 1519-1526.