Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Lucas, Daniel ^a,f   Delgado García, José M ^b   Escudero, Beatriz ^c   Albo, Carmen ^c   Aza, Ana ^d   Acín Pérez, Rebeca ^c   Torres, Yaima ^c   Moreno, Paz ^c   Enríquez, José Antonio ^c   Samper, Enrique ^c   Blanco, Luis ^d   Fairén, Alfonso ^e   Bernad, Antonio ^c   Gruart, Agnès ^b  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^d CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^e MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; DNA POLYMERASE; DNA POLYMERASE MU; GROWTH HORMONE; PROLACTIN; PROLACTIN 1; SECURIN; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; ZINC TRANSPORTER; ZINC TRANSPORTER 3;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DNA REPAIR; ENDOCRINE FUNCTION; ENZYME ACTIVITY; EXCITATORY POSTSYNAPTIC POTENTIAL; EYELID REFLEX; GENE; GENE EXPRESSION; GROWTH HORMONE GENE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; INSULIN LIKE GROWTH FACTOR RECEPTOR 1 GENE; LONG TERM POTENTIATION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PROK1 GENE; PROLACTIN 1 GENE; PTTG1 GENE; RECEPTOR GENE; STATE DEPENDENT LEARNING; SYNAPSE; WILD TYPE;

AGING; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CONDITIONING, CLASSICAL; DNA; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; HIPPOCAMPUS; LEARNING; LOCOMOTION; LONG-TERM POTENTIATION; MALE; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; PHENOTYPE; REPRODUCIBILITY OF RESULTS; TEMPERATURE;

MUS;

EID: 84871910142     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053243     Document Type: Article

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