Zinc transporter 7 induced by high glucose attenuates epithelial-to- mesenchymal transition of peritoneal mesothelial cells

Biological Trace Element Research

Volumn 151, Issue 1, 2013, Pages 138-147

  Zhang, Xiuli ^a,b   Liang, Dan ^c,d   Guo, Baolei ^e   Sun, Lixia ^a   Chi, Zhi Hong ^a   Cai, Yuan ^a   Wang, Lining ^a   Ma, Jianfei ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Benxi Railway Hospital   (China)

^c GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^d Troops of 95935 Unit PR China   (China)

^e Shenyang Orthopaedics Hospital   (China)

Author keywords

Epithelial to mesenchymal transition; High glucose; Rat peritoneal mesothelial cells; siRNA; Zinc transporter

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; GLUCOSE; SMAD3 PROTEIN; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; ZINC; ZINC TRANSPORTER; ZINC TRANSPORTER 7;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; INTRACELLULAR SIGNALING; MESOTHELIUM CELL; MOLECULAR INTERACTION; NONHUMAN; PERITONEUM CELL; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA INTERFERENCE; ZINC TRANSPORTER GENE;

ANIMALS; BLOTTING, WESTERN; CATION TRANSPORT PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION; GLUCOSE; MICROSCOPY, FLUORESCENCE; PERITONEUM; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD PROTEINS; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

RATTUS;

EID: 84871877202     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9533-3     Document Type: Article

References (35)

1. Yanez-Mo M, Lara-Pezzi E, Selgas R, Ramirez-Huesca M, Dominguez-Jimenez C, Jimenez-Heffernan JA et al (2003) Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med 348:403-413 (Pubitemid 36159357)
2. Chung SH, Stenvinkel P, Bergstrom J, Lindholm B (2000) Biocompatibility of new peritoneal dialysis solutions: what can we hope to achieve? Perit Dial Int 20(Suppl 5):S57-S67
3. Ha H, Yu MR, Lee HB (2001) High glucose-induced PKC activation mediates TGF-beta 1 and fibronectin synthesis by peritoneal mesothelial cells. Kidney Int 59:463-470 (Pubitemid 32157911)
4. Cendoroglo M, Sundaram S, Jaber BL, Pereira BJ (1998) Effect of glucose concentration, osmolality, and sterilization process of peritoneal dialysis fluids on cytokine production by peripheral blood mononuclear cells and polymorphonuclear cell functions in vitro. Am J Kidney Dis 31:273-282 (Pubitemid 28106419)
5. Loureiro J, Schilte M, Aguilera A, Albar-Vizcaino P, Ramirez-Huesca M, Perez-Lozano ML et al (2010) BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure. Nephrol Dial Transplant 25:1098-1108
6. Cannito S, Novo E, di Bonzo LV, Busletta C, Colombatto S, Parola M (2009) Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease. Antioxid Redox Signal 12:1383-1430
7. Yao Q, Pawlaczyk K, Ayala ER, Styszynski A, Breborowicz A, Heimburger O et al (2008) The role of the TGF/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions. Nephron Exp Nephrol 109:e71-e78
8. Yu MA, Shin KS, Kim JH, Kim YI, Chung SS, Park SH (2009) HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium. J Am Soc Nephrol 20:567-581
9. Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79-118 (Pubitemid 23065434)
10. Walsh CT, Sandstead HH, Prasad AS, Newberne PM, Fraker PJ (1994) Zinc: health effects and research priorities for the 1990s. Environ Health Perspect 102(Suppl 2):5-46 (Pubitemid 24217794)
11. Kambe T, Yamaguchi-Iwai Y, Sasaki R, Nagao M (2004) Overview of mammalian zinc transporters. Cell Mol Life Sci 61:49-68 (Pubitemid 38121899)
12. Palmiter RD, Huang L (2004) Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers. Pflugers Arch 447:744-751 (Pubitemid 38241460)
13. Cousins RJ, Liuzzi JP, Lichten LA (2006) Mammalian zinc transport, trafficking, and signals. J Biol Chem 281:24085-24089 (Pubitemid 44274182)
14. Takahashi M, Saito H, Higashimoto M, Hibi T (2007) Possible inhibitory effect of oral zinc supplementation on hepatic fibrosis through downregulation of TIMP-1: a pilot study. Hepatol Res 37:405-409 (Pubitemid 46915784)
15. Wang L, Zhou Z, Saari JT, Kang YJ (2005) Alcohol-induced myocardial fibrosis in metallothionein-null mice: prevention by zinc supplementation. Am J Pathol 167:337-344 (Pubitemid 43026091)
16. Gandhi MS, Deshmukh PA, Kamalov G, Zhao T, Zhao W, Whaley JT et al (2008) Causes and consequences of zinc dyshomeostasis in rats with chronic aldosteronism. J Cardiovasc Pharmacol 52:245-252
17. Van Biervliet S, Vande Velde S, Van Biervliet JP, Robberecht E (2008) The effect of zinc supplements in cystic fibrosis patients. Ann Nutr Metab 52:152-156 (Pubitemid 351723136)
18. Besecker B, Bao S, Bohacova B, Papp A, Sadee W, Knoell DL (2008) The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia. Am J Physiol Lung Cell Mol Physiol 294:L1127-L1136
19. Liuzzi JP, Lichten LA, Rivera S, Blanchard RK, Aydemir TB, Knutson MD et al (2005) Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response. Proc Natl Acad Sci U S A 102:6843-6848 (Pubitemid 40675404)
20. Yamashita S, Miyagi C, Fukada T, Kagara N, Che YS, Hirano T (2004) Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer. Nature 429:298-302 (Pubitemid 38684814)
21. Zhao L, Chen W, Taylor KM, Cai B, Li X (2007) LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway. Biochem Biophys Res Commun 363:82-88 (Pubitemid 47432916)
22. Hjelle JT, Golinska BT, Waters DC, Steidley KR, McCarroll DR, Dobbie JW (1989) Isolation and propagation in vitro of peritoneal mesothelial cells. Perit Dial Int 9:341-347 (Pubitemid 20026350)
23. Sim DL, Yeo WM, Chow VT (2002) The novel human HUEL (C4orf1) protein shares homology with the DNA-binding domain of the XPA DNA repair protein and displays nuclear translocation in a cell cycle-dependent manner. Int J Biochem Cell Biol 34:487-504 (Pubitemid 34242761)
24. Margetts PJ, Bonniaud P, Liu L, Hoff CM, Holmes CJ, West-Mays JA et al (2005) Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. J Am Soc Nephrol 16:425-436 (Pubitemid 41725138)
25. Prasad AS (2008) Clinical, immunological, anti-inflammatory and antioxidant roles of zinc. Exp Gerontol 43:370-377 (Pubitemid 351540838)
26. Bao S, Knoell DL (2006) Zinc modulates cytokine-induced lung epithelial cell barrier permeability. Am J Physiol Lung Cell Mol Physiol 291:L1132-L1141 (Pubitemid 44904519)
27. Mengheri E, Nobili F, Vignolini F, Pesenti M, Brandi G, Biavati B (1999) Bifidobacterium animalis protects intestine from damage induced by zinc deficiency in rats. J Nutr 129:2251-2257
28. Fernandez-Madrid F, Prasad AS, Oberleas D (1973) Effect of zinc deficiency on nucleic acids, collagen, and noncollagenous protein of the connective tissue. J Lab Clin Med 82:951-961
29. Kirschke CP, Huang L (2003) ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus. J Biol Chem 278:4096-4102 (Pubitemid 36801145)
30. Suzuki T, Ishihara K, Migaki H, Nagao M, Yamaguchi-Iwai Y, Kambe T (2005) Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells. J Biol Chem 280:30956-30962 (Pubitemid 41291828)
31. Suzuki T, Ishihara K, Migaki H, Matsuura W, Kohda A, Okumura K et al (2005) Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane. J Biol Chem 280:637-643 (Pubitemid 40165030)
32. Jiang Y, Xie X, Li Z, Wang Z, Zhang Y, Ling ZQ et al (2011) Functional cooperation of RKTG with p53 in tumorigenesis and epithelial-mesenchymal transition. Cancer Res 71:2959-2968
33. Ornatowski W, Poschet JF, Perkett E, Taylor-Cousar JL, Deretic V (2007) Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity. J Clin Invest 117:3489-3497 (Pubitemid 350097004)
34. Koli K, Saharinen J, Hyytiainen M, Penttinen C, Keski-Oja J (2001) Latency, activation, and binding proteins of TGF-beta. Microsc Res Tech 52:354-362 (Pubitemid 32167823)
35. Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113:685-700 (Pubitemid 36724933)