Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 19, 2005, Pages 6843-6848

  Liuzzi, Juan P ^a   Lichten, Louis A ^a   Rivera, Seth ^b   Blanchard, Raymond K ^a,c   Aydemir, Tolunay Beker ^a   Knutson, Mitchell D ^a   Ganz, Tomas ^b   Cousins, Robert J ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SuperArray Bioscience Corporation   (United States)

Author keywords

Endotoxemia; Hepatic; Inflammation; Knockout mice; Slc39a14

Indexed keywords

FERROPORTIN 1; FLUORESCENT DYE; HEPCIDIN; INTERLEUKIN 6; MESSENGER RNA; METALLOTHIONEIN; ZINC; ZINC TRANSPORTER;

ACUTE PHASE RESPONSE; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DNA TRANSFECTION; GENE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; IRON DEFICIENCY; KNOCKOUT MOUSE; LIVER; LIVER CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ZINC BLOOD LEVEL; ZINC DEFICIENCY; ZIP GENE; ZNT GENE;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, NORTHERN; CATION TRANSPORT PROTEINS; CELL LINE; CELL MEMBRANE; DNA; DNA, COMPLEMENTARY; EPITOPES; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TISSUE DISTRIBUTION; TRANSFECTION; TURPENTINE; UP-REGULATION; ZINC;

EID: 18744376312     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502257102     Document Type: Article

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