The novel human HUEL (C4orf1) protein shares homology with the DNA-binding domain of the XPA DNA repair protein and displays nuclear translocation in a cell cycle-dependent manner

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 5, 2002, Pages 487-504

  Sim, Del L C ^a   Yeo, W M ^a   Chow, Vincent T K ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

C4orf1; Cell cycle; HUEL; Nuclear translocation; Xeroderma pigmentosum complementation group A

Indexed keywords

AMINO ACID DERIVATIVE; COMPLEMENTARY DNA; DEOXYRIBONUCLEOPROTEIN; LEUCINE ZIPPER PROTEIN; NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL DIVISION; CELL SYNCHRONIZATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CPG ISLAND; DNA REPAIR; DNA SYNTHESIS; GC RICH SEQUENCE; GENE DELETION; GENE ISOLATION; GENE MAPPING; GENETIC CODE; GENOME ANALYSIS; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR EVOLUTION; NUCLEAR LOCALIZATION SIGNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION; VALIDATION PROCESS; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATION TRANSPORT PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; DNA REPAIR; DNA-BINDING PROTEINS; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES; URINARY BLADDER NEOPLASMS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

MAMMALIA; MURINAE;

EID: 0036131212     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(01)00156-X     Document Type: Article

References (51)

1. The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and encodes a nuclear protein containing the nuclear receptor interaction motif
2. The DNA damage-recognition problem in human and other eukaryotic cells: The XPA damage binding protein
3. The simultaneous extraction of high-molecular-weight DNA and of RNA from solid tumors
4. Genomic organization and mapping of the human HEP-COP gene (COPA) to 1q
5. The human DENN gene: Genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22
6. Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells
7. Basic local alignment search tool
8. Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner
9. A catalogue of splice junction sequences
10. Splicing of messenger RNA precursors
11. Association of intron phases with conservation at splice site sequences and evolution of spliceosomal introns
12. Regulation of alternative splicing of CD45 by antagonistic effects of SR protein splicing factors
13. Exon-skipping in BCR/ABL is induced by ABL exon 2
14. CpG islands in vertebrate genomes
15. Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain
16. Mutational analysis of the structure and function of the xeroderma pigmentosum group A complementing protein. Identification of essential domains for nuclear localization and DNA excision repair
17. Molecular cloning of human XPAC gene homologs from chicken, Xenopus laevis and Drosophila melanogaster
18. Identification of intrinsic order and disorder in the DNA repair protein XPA
19. Identification of a damaged-DNA-binding domain of the XPA protein
20. Distribution of mutations in the human xeroderma pigmentosum group A gene and their relationships to the functional regions of the DNA damage recognition protein
21. NMR structure of a specific DNA complex of Zn-containing DNA-binding domain of GATA-1
22. Structural features of the minimal DNA-binding domain (M98-F219) of human nucleotide excision repair protein XPA
23. Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA
24. Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA
25. Deletion of two regions on chromosome 4 in bladder carcinoma: Definition of a critical 750 kb region at 4p16.3
26. Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma
27. Regulated nuclear localization of stress-responsive factors: How the nuclear trafficking of protein kinases and transcription factors contributes to cell survival
28. Nuclear transport and transcription
29. Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
30. Regulation of E2F4 mitogenic activity during terminal differentiation by its heterodimerization partners for nuclear translocation
31. Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus
32. Phosphorylation of transcription factors and control of the cell cycle
33. Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B sub-unit
34. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha
35. Nuclear entry, oligomerization, and DNA-binding of the Drosophila heat shock transcription factor are regulated by a unique nuclear localization sequence
36. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
37. Wild-type p53 protein shows calcium-dependent binding to F-actin
38. Regulation of DNA-binding and transactivation in p53 by nuclear localization and phosphorylation
39. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
40. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
41. A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of sub-cellular localization and p53 activity by NES masking
42. Number and location of AUUUA motifs: Role in regulating transiently expressed RNAs
43. AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A)
44. Cloning, expression, and purification of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase: Crystallization of nucleic acid complexes
45. Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: Functional implications for template-primer binding to the fingers domain
46. Systematic identification of mitotic phosphoproteins
47. Metaphase protein phosphorylation in Xenopus laevis eggs
48. Phosphorylation changes associated with the early cell cycle in Xenopus eggs
49. Synthesis of RNA and protein during mitosis in mammalian tissue culture cells
50. Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb
51. The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phoshorylated and excluded from the condensed chromosomes during mitosis