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Volumn 18, Issue 1, 2013, Pages 120-136

A nanoformulation of siRNA and its role in cancer therapy: In vitro and in vivo evaluation

Author keywords

Apoptosis; Bcl 2; Cancer; Chitosan; Nanoformulation; RNA interference; siRNA

Indexed keywords

CHITOSAN; CISPLATIN; NANOPARTICLE; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 84871830648     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-012-0043-2     Document Type: Article
Times cited : (25)

References (44)
  • 1
    • 0034057320 scopus 로고    scopus 로고
    • Apoptosis in cancer
    • Lowe, S. W. and Lin, A. W. Apoptosis in cancer. Carcinogenesis21 (2000) 485-496.
    • (2000) Carcinogenesis , vol.21 , pp. 485-496
    • Lowe, S.W.1    Lin, A.W.2
  • 2
    • 33645902688 scopus 로고    scopus 로고
    • Apoptotic pathways in cancer progression and treatment
    • T. Finkel and J. S. Gutkind (Eds.), Hoboken, NJ, USA: John Wiley & Sons, Inc
    • Chandra, J. and Kaufmann, S. H. Apoptotic pathways in cancer progression and treatment, in: Signal Transduction and Human Disease (Finkel, T. and Gutkind, J. S. Eds.), John Wiley & Sons, Inc., Hoboken, NJ, USA. (2003) 143-170. DOI: 10. 1002/0471482706. ch4.
    • (2003) Signal Transduction and Human Disease , pp. 143-170
    • Chandra, J.1    Kaufmann, S.H.2
  • 3
    • 0037018277 scopus 로고    scopus 로고
    • Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression
    • Fulda, S., Meyer, E. and Debatin, K. M. Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. Oncogene21 (2002) 2283-2291.
    • (2002) Oncogene , vol.21 , pp. 2283-2291
    • Fulda, S.1    Meyer, E.2    Debatin, K.M.3
  • 4
    • 0038786580 scopus 로고    scopus 로고
    • Apoptosis-targeted therapies for cancer
    • Reed, J. C. Apoptosis-targeted therapies for cancer. Cancer Cell3 (2003) 17-30.
    • (2003) Cancer Cell , vol.3 , pp. 17-30
    • Reed, J.C.1
  • 5
    • 14644407525 scopus 로고    scopus 로고
    • The role of apoptosis in cancer development and treatment response
    • Brown, J. M. and Attardi, L. D. The role of apoptosis in cancer development and treatment response. Nat. Rev. Cancer5 (2005) 231-237.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 231-237
    • Brown, J.M.1    Attardi, L.D.2
  • 6
    • 0037075898 scopus 로고    scopus 로고
    • Activation of the p53 tumor suppressor protein
    • Vousden, K. H. Activation of the p53 tumor suppressor protein. Biochim. Biophys. Acta-Rev. Cancer1602 (2002) 47-59.
    • (2002) Biochim. Biophys. Acta-Rev. Cancer , vol.1602 , pp. 47-59
    • Vousden, K.H.1
  • 7
    • 0033118475 scopus 로고    scopus 로고
    • Apoptosis, p53, and tumor cell sensitivity to anticancer agents
    • Brown J. M. and Wouters, B. G. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 59 (1999) 1391-1404.
    • (1999) Cancer Res. , vol.59 , pp. 1391-1404
    • Brown, J.M.1    Wouters, B.G.2
  • 9
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: arbiters of cell survival
    • Adams J. M. and Cory, S. The Bcl-2 protein family: arbiters of cell survival. Science281 (1998) 1322-1345.
    • (1998) Science , vol.281 , pp. 1322-1345
    • Adams, J.M.1    Cory, S.2
  • 10
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: roles in cell survival and oncogenesis
    • Cory, S., Huang, D. C. S. and Adams, J. M. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene22 (2003) 8590-8607.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.S.2    Adams, J.M.3
  • 11
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed, J. C. Dysregulation of apoptosis in cancer. J. Clin. Oncol. 17 (1999) 2941-2961.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2941-2961
    • Reed, J.C.1
  • 12
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T. and Taniguchi, T. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science288 (2000) 1053-1061.
    • (2000) Science , vol.288 , pp. 1053-1061
    • Oda, E.1    Ohki, R.2    Murasawa, H.3    Nemoto, J.4    Shibue, T.5    Yamashita, T.6    Tokino, T.7    Taniguchi, T.8
  • 13
    • 0035514046 scopus 로고    scopus 로고
    • Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim
    • Bouillet, P., Cory, S., Zhang, L. C., Strasser, A. and Adams, J. M. Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev. Cell1 (2001) 645-653.
    • (2001) Dev. Cell , vol.1 , pp. 645-653
    • Bouillet, P.1    Cory, S.2    Zhang, L.C.3    Strasser, A.4    Adams, J.M.5
  • 15
    • 0032146987 scopus 로고    scopus 로고
    • Bcl-2-family proteins: the role of the BH3 domain in apoptosis
    • Kelekar A. and Thompson, C. B. Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol. 8 (1998) 324-330.
    • (1998) Trends Cell Biol. , vol.8 , pp. 324-330
    • Kelekar, A.1    Thompson, C.B.2
  • 16
    • 0034641980 scopus 로고    scopus 로고
    • Apoptosis in development
    • Meier, P., Finch A. and Evan, G. Apoptosis in development. Nature6805 (2000) 796-801.
    • (2000) Nature , vol.6805 , pp. 796-801
    • Meier, P.1    Finch, A.2    Evan, G.3
  • 18
    • 17244380208 scopus 로고    scopus 로고
    • Application of RNAi to cancer research and therapy
    • Tan, F. L. and Yin, J. Q. Application of RNAi to cancer research and therapy. Front Biosci. 10 (2005) 1946-1960.
    • (2005) Front Biosci. , vol.10 , pp. 1946-1960
    • Tan, F.L.1    Yin, J.Q.2
  • 20
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • Akhtar, S. and Benter, I. F. Nonviral delivery of synthetic siRNAs in vivo. J. Clin. Invest. 117 (2007) 3623-3632.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3623-3632
    • Akhtar, S.1    Benter, I.F.2
  • 21
    • 1842434428 scopus 로고    scopus 로고
    • Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics
    • Bozkir, A. and Saka, O. M. Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics. Drug Deliv. 11 (2004) 107-112.
    • (2004) Drug Deliv. , vol.11 , pp. 107-112
    • Bozkir, A.1    Saka, O.M.2
  • 23
    • 33749844509 scopus 로고    scopus 로고
    • Development and characterisation of chitosan nanoparticles for siRNA delivery
    • Katas, H. and Alpar, H. O. Development and characterisation of chitosan nanoparticles for siRNA delivery. J. Control. Release115 (2006) 216-225.
    • (2006) J. Control. Release , vol.115 , pp. 216-225
    • Katas, H.1    Alpar, H.O.2
  • 24
    • 7444268954 scopus 로고    scopus 로고
    • Recent advances on chitosan-based micro-and nanoparticles in drug delivery
    • Agnihotri, S. A., Mallikarjuna N. N. and Aminabhavi, T. M. Recent advances on chitosan-based micro-and nanoparticles in drug delivery, J. Control. Release100 (2004) 5-28.
    • (2004) J. Control. Release , vol.100 , pp. 5-28
    • Agnihotri, S.A.1    Mallikarjuna, N.N.2    Aminabhavi, T.M.3
  • 25
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
    • Roy, K., Mao, H. Q., Huang, S. K. and Leong, K. W. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat. Med. 5 (1999) 387-397.
    • (1999) Nat. Med. , vol.5 , pp. 387-397
    • Roy, K.1    Mao, H.Q.2    Huang, S.K.3    Leong, K.W.4
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods65 (1983) 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot, F. and Lang, R. Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods89 (1986) 271-277.
    • (1986) J. Immunol. Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 29
    • 71949127621 scopus 로고
    • Process for amplifying nucleic acid sequences
    • Mullis, K. B. Process for amplifying nucleic acid sequences. Google Patents (1987).
    • (1987) Google Patents
    • Mullis, K.B.1
  • 31
    • 0026580422 scopus 로고
    • Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction
    • Lanciotti, R. S., Calisher, C. H., Gubler, D. J., Chang, G J. and Vorndam, A. V. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J. Clin. Microbiol. 30 (1992) 545-560.
    • (1992) J. Clin. Microbiol. , vol.30 , pp. 545-560
    • Lanciotti, R.S.1    Calisher, C.H.2    Gubler, D.J.3    Chang, G.J.4    Vorndam, A.V.5
  • 32
    • 0019551730 scopus 로고
    • Western blotting: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • Burnette, W. N. Western blotting: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112 (1981) 195-203.
    • (1981) Anal. Biochem. , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 33
    • 38349125637 scopus 로고    scopus 로고
    • siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma
    • De Martimprey, H., Bertrand, J. R., Fusco, A., Santoro, M., Couvreur, P., Vauthier, C. and Malvy, C. siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma. Nucleic Acids Res. 36 (2008) e2-e2.
    • (2008) Nucleic Acids Res. , vol.36
    • de Martimprey, H.1    Bertrand, J.R.2    Fusco, A.3    Santoro, M.4    Couvreur, P.5    Vauthier, C.6    Malvy, C.7
  • 34
    • 0036073240 scopus 로고    scopus 로고
    • The molecular perspective: Bcl-2 and apoptosis
    • Goodsell, D. S. The molecular perspective: Bcl-2 and apoptosis. The Oncologist7 (2002) 259-260.
    • (2002) The Oncologist , vol.7 , pp. 259-260
    • Goodsell, D.S.1
  • 35
    • 64249135764 scopus 로고    scopus 로고
    • Novel agents on the horizon for cancer therapy
    • Ma, W. W. and Adjei, A. A. Novel agents on the horizon for cancer therapy. CA Cancer J. Clin. 59 (2009) 111-137.
    • (2009) CA Cancer J. Clin. , vol.59 , pp. 111-137
    • Ma, W.W.1    Adjei, A.A.2
  • 38
    • 77954592089 scopus 로고    scopus 로고
    • STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL
    • Verma, N. K., Davies, A. M., Long, A., Kelleher, D. and Volkov, Y. STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL. Cell. Mol. Biol. Lett. 15 (2010) 342-355.
    • (2010) Cell. Mol. Biol. Lett. , vol.15 , pp. 342-355
    • Verma, N.K.1    Davies, A.M.2    Long, A.3    Kelleher, D.4    Volkov, Y.5
  • 39
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • Akhtar, S. and Benter, I. F. Nonviral delivery of synthetic siRNAs in vivo. J. Clin. Invest. 117 (2007) 3623-3643.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3623-3643
    • Akhtar, S.1    Benter, I.F.2
  • 40
    • 75149133614 scopus 로고    scopus 로고
    • Chitosan-based formulations for delivery of DNA and siRNA
    • Mao, S., Sun, W. and Kissel, T. Chitosan-based formulations for delivery of DNA and siRNA. Adv. Drug Delivery Rev. 62 (2010) 12-27.
    • (2010) Adv. Drug Delivery Rev. , vol.62 , pp. 12-27
    • Mao, S.1    Sun, W.2    Kissel, T.3
  • 41
    • 46649092718 scopus 로고    scopus 로고
    • The use of chitosan formulations in cancer therapy
    • Dass, C. R. and Choong, P. F. M. The use of chitosan formulations in cancer therapy. J. Microencapsul. 25 (2008) 275-279.
    • (2008) J. Microencapsul. , vol.25 , pp. 275-279
    • Dass, C.R.1    Choong, P.F.M.2
  • 44
    • 84870935425 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin
    • Spandana, K., Hitesh, J., Vasanth, R. P., Jesil, M. A., Mallikarjuna, R. C. and Venkata R. J. In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin. Exp. Mol. Pathol. 2012; http://dx. doi. org/10. 1016/j. yexmp. 2012. 10. 007.
    • (2012) Exp. Mol. Pathol
    • Spandana, K.1    Hitesh, J.2    Vasanth, R.P.3    Jesil, M.A.4    Mallikarjuna, R.C.5    Venkata, R.J.6


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