-
1
-
-
0242383401
-
Obesity--is it a genetic disorder?
-
Loos RJ, Bouchard C. Obesity--is it a genetic disorder? J Intern Med 2003; 254: 401-425.
-
(2003)
J Intern Med
, vol.254
, pp. 401-425
-
-
Loos, R.J.1
Bouchard, C.2
-
2
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley MA, Smart JL, Rubinstein M, et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 2001; 411: 480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
-
3
-
-
0037178730
-
Activation of central melanocortin pathways by fenfluramine
-
Heisler LK, Cowley MA, Tecott LH, et al. Activation of central melanocortin pathways by fenfluramine. Science 2002; 297: 609-611.
-
(2002)
Science
, vol.297
, pp. 609-611
-
-
Heisler, L.K.1
Cowley, M.A.2
Tecott, L.H.3
-
4
-
-
0037057802
-
The need to feed: homeostatic and hedonic control of eating
-
Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron 2002; 36: 199-211.
-
(2002)
Neuron
, vol.36
, pp. 199-211
-
-
Saper, C.B.1
Chou, T.C.2
Elmquist, J.K.3
-
5
-
-
0043026937
-
Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions
-
Raffin-Sanson ML, de Keyzer Y, Bertagna X. Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions. Eur J Endocrinol 2003; 149: 79-90.
-
(2003)
Eur J Endocrinol
, vol.149
, pp. 79-90
-
-
Raffin-Sanson, M.L.1
de Keyzer, Y.2
Bertagna, X.3
-
6
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG. Central nervous system control of food intake. Nature 2000; 404: 661-671.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr, D.3
Seeley, R.J.4
Baskin, D.G.5
-
7
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88: 131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
-
8
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 2003; 348: 1085-1095.
-
(2003)
N Engl J Med
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.3
Lank, E.J.4
Cheetham, T.5
O'Rahilly, S.6
-
9
-
-
0343953074
-
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
-
Farooqi IS, Yeo GS, Keogh JM, et al. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest 2000; 106: 271-279.
-
(2000)
J Clin Invest
, vol.106
, pp. 271-279
-
-
Farooqi, I.S.1
Yeo, G.S.2
Keogh, J.M.3
-
10
-
-
0033927916
-
Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
-
Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 2000; 106: 253-262.
-
(2000)
J Clin Invest
, vol.106
, pp. 253-262
-
-
Vaisse, C.1
Clement, K.2
Durand, E.3
Hercberg, S.4
Guy-Grand, B.5
Froguel, P.6
-
11
-
-
0033818103
-
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass
-
Chen AS, Marsh DJ, Trumbauer ME, et al. Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass. Nat Genet 2000; 26: 97-102.
-
(2000)
Nat Genet
, vol.26
, pp. 97-102
-
-
Chen, A.S.1
Marsh, D.J.2
Trumbauer, M.E.3
-
12
-
-
0034456398
-
A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse
-
Butler AA, Kesterson RA, Khong K, et al. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology 2000; 141: 3518-3521.
-
(2000)
Endocrinology
, vol.141
, pp. 3518-3521
-
-
Butler, A.A.1
Kesterson, R.A.2
Khong, K.3
-
13
-
-
24144443764
-
Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity
-
Feng N, Young SF, Aguilera G, et al. Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity. Diabetes 2005; 54: 2663-2667.
-
(2005)
Diabetes
, vol.54
, pp. 2663-2667
-
-
Feng, N.1
Young, S.F.2
Aguilera, G.3
-
14
-
-
84991847410
-
The role of melanocortin 3 receptor gene in childhood obesity
-
Lee YS, Poh LK, Kek BL, Loke KY. The role of melanocortin 3 receptor gene in childhood obesity. Diabetes 2007; 56: 2622-2630.
-
(2007)
Diabetes
, vol.56
, pp. 2622-2630
-
-
Lee, Y.S.1
Poh, L.K.2
Kek, B.L.3
Loke, K.Y.4
-
15
-
-
0036963510
-
A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity
-
Lee YS, Poh LK, Loke KY. A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity. J Clin Endocrinol Metab 2002; 87: 1423-1426.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1423-1426
-
-
Lee, Y.S.1
Poh, L.K.2
Loke, K.Y.3
-
16
-
-
0342804352
-
Melanocortin-3 receptor mRNA expression in pro-opiomelanocortin neurones of the rat arcuate nucleus
-
Jegou S, Boutelet I, Vaudry H. Melanocortin-3 receptor mRNA expression in pro-opiomelanocortin neurones of the rat arcuate nucleus. J Neuroendocrinol 2000; 12: 501-505.
-
(2000)
J Neuroendocrinol
, vol.12
, pp. 501-505
-
-
Jegou, S.1
Boutelet, I.2
Vaudry, H.3
-
17
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu B, Goulding EH, Zang K, et al. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 2003; 6: 736-742.
-
(2003)
Nat Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
-
18
-
-
7044262828
-
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
-
Yeo GS, Connie Hung CC, Rochford J, et al. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nat Neurosci 2004; 7: 1187-1189.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1187-1189
-
-
Yeo, G.S.1
Connie, H.C.2
Rochford, J.3
-
19
-
-
33749859790
-
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
-
Oh IS, Shimizu H, Satoh T, et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 2006; 443: 709-712.
-
(2006)
Nature
, vol.443
, pp. 709-712
-
-
Oh, I.S.1
Shimizu, H.2
Satoh, T.3
-
20
-
-
27344433932
-
Agouti-related peptide-expressing neurons are mandatory for feeding
-
Gropp E, Shanabrough M, Borok E, et al. Agouti-related peptide-expressing neurons are mandatory for feeding. Nat Neurosci 2005; 8: 1289-1291.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1289-1291
-
-
Gropp, E.1
Shanabrough, M.2
Borok, E.3
-
21
-
-
0031687052
-
Assignment of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping
-
Sundaramurthy D, Campbell DA, Leek JP, Markham AF, Pieri LF. Assignment of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping. Cytogenet Cell Genet 1998; 82: 97-98.
-
(1998)
Cytogenet Cell Genet
, vol.82
, pp. 97-98
-
-
Sundaramurthy, D.1
Campbell, D.A.2
Leek, J.P.3
Markham, A.F.4
Pieri, L.F.5
-
22
-
-
0027227288
-
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor
-
Gantz I, Miwa H, Konda Y, et al. Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J Biol Chem 1993; 268: 15174-15179.
-
(1993)
J Biol Chem
, vol.268
, pp. 15174-15179
-
-
Gantz, I.1
Miwa, H.2
Konda, Y.3
-
23
-
-
0028134706
-
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
-
Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 1994; 8: 1298-1308.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1298-1308
-
-
Mountjoy, K.G.1
Mortrud, M.T.2
Low, M.J.3
Simerly, R.B.4
Cone, R.D.5
-
24
-
-
0032524392
-
Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems
-
Mountjoy KG, Wild JM. Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems. Brain Res Dev Brain Res 1998; 107: 309-314.
-
(1998)
Brain Res Dev Brain Res
, vol.107
, pp. 309-314
-
-
Mountjoy, K.G.1
Wild, J.M.2
-
25
-
-
0036257961
-
Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with early-onset obesity
-
Miraglia Del Giudice E, Cirillo G, Nigro V, et al. Low frequency of melanocortin-4 receptor (MC4R) mutations in a Mediterranean population with early-onset obesity. Int J Obes Relat Metab Disord 2002; 26: 647-651.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 647-651
-
-
Miraglia, D.G.E.1
Cirillo, G.2
Nigro, V.3
-
26
-
-
18644363563
-
Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis cohort
-
Jacobson P, Ukkola O, Rankinen T, et al. Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: the Swedish Obese Subjects, the HERITAGE Family Study, and a Memphis cohort. J Clin Endocrinol Metab 2002; 87: 4442-4446.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4442-4446
-
-
Jacobson, P.1
Ukkola, O.2
Rankinen, T.3
-
27
-
-
0141564582
-
Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity
-
Hinney A, Hohmann S, Geller F, et al. Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity. J Clin Endocrinol Metab 2003; 88: 4258-4267.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4258-4267
-
-
Hinney, A.1
Hohmann, S.2
Geller, F.3
-
28
-
-
0033495921
-
Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese
-
Ohshiro Y, Sanke T, Ueda K, et al. Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese. Ann Hum Genet 1999; 63: 483-487.
-
(1999)
Ann Hum Genet
, vol.63
, pp. 483-487
-
-
Ohshiro, Y.1
Sanke, T.2
Ueda, K.3
-
29
-
-
12244281827
-
Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity
-
Larsen LH, Echwald SM, Sorensen TI, Andersen T, Wulff BS, Pedersen O. Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity. J Clin Endocrinol Metab 2005; 90: 219-224.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 219-224
-
-
Larsen, L.H.1
Echwald, S.M.2
Sorensen, T.I.3
Andersen, T.4
Wulff, B.S.5
Pedersen, O.6
-
30
-
-
33746040561
-
Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population
-
Rong R, Tao YX, Cheung BM, Xu A, Cheung GC, Lam KS. Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population. Clin Endocrinol (Oxf) 2006; 65: 198-205.
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, pp. 198-205
-
-
Rong, R.1
Tao, Y.X.2
Cheung, B.M.3
Xu, A.4
Cheung, G.C.5
Lam, K.S.6
-
31
-
-
33846489214
-
Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents
-
Wang CL, Liang L, Wang HJ, Fu JF, Hebebrand J, Hinney A. Several mutations in the melanocortin 4 receptor gene are associated with obesity in Chinese children and adolescents. J Endocrinol Invest 2006; 29: 894-898.
-
(2006)
J Endocrinol Invest
, vol.29
, pp. 894-898
-
-
Wang, C.L.1
Liang, L.2
Wang, H.J.3
Fu, J.F.4
Hebebrand, J.5
Hinney, A.6
-
32
-
-
34347406987
-
The relationship between body mass index and per cent body fat in the severely obese
-
Adams TD, Heath EM, LaMonte MJ, et al. The relationship between body mass index and per cent body fat in the severely obese. Diabetes Obes Metab 2007; 9: 498-505.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 498-505
-
-
Adams, T.D.1
Heath, E.M.2
LaMonte, M.J.3
-
33
-
-
40749107004
-
Novel melanocortin 4 receptor gene mutations in severely obese children
-
Lee YS, Poh LK, Kek BL, Loke KY. Novel melanocortin 4 receptor gene mutations in severely obese children. Clin Endocrinol (Oxf) 2008; 68: 529-535.
-
(2008)
Clin Endocrinol (Oxf)
, vol.68
, pp. 529-535
-
-
Lee, Y.S.1
Poh, L.K.2
Kek, B.L.3
Loke, K.Y.4
-
34
-
-
0033343736
-
Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans
-
Hinney A, Schmidt A, Nottebom K, et al. Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans. J Clin Endocrinol Metab 1999; 84: 1483-1486.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 1483-1486
-
-
Hinney, A.1
Schmidt, A.2
Nottebom, K.3
-
35
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity
-
Yeo GS, Farooqi IS, Aminian S, Halsall DJ, Stanhope RG, O'Rahilly S. A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat Genet 1998; 20: 111-112.
-
(1998)
Nat Genet
, vol.20
, pp. 111-112
-
-
Yeo, G.S.1
Farooqi, I.S.2
Aminian, S.3
Halsall, D.J.4
Stanhope, R.G.5
O'Rahilly, S.6
-
36
-
-
33646423288
-
Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany
-
Hinney A, Bettecken T, Tarnow P, et al. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J Clin Endocrinol Metab 2006; 91: 1761-1769.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1761-1769
-
-
Hinney, A.1
Bettecken, T.2
Tarnow, P.3
-
37
-
-
52749092130
-
Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees
-
Stutzmann F, Tan K, Vatin V, et al. Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees. Diabetes 2008; 57: 2511-2518.
-
(2008)
Diabetes
, vol.57
, pp. 2511-2518
-
-
Stutzmann, F.1
Tan, K.2
Vatin, V.3
-
38
-
-
33745036725
-
Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist
-
Xiang Z, Litherland SA, Sorensen NB, et al. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist. Biochemistry 2006; 45: 7277-7288.
-
(2006)
Biochemistry
, vol.45
, pp. 7277-7288
-
-
Xiang, Z.1
Litherland, S.A.2
Sorensen, N.B.3
-
39
-
-
34547839796
-
Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene
-
Stutzmann F, Vatin V, Cauchi S, et al. Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene. Hum Mol Genet 2007; 16:1837-1844.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1837-1844
-
-
Stutzmann, F.1
Vatin, V.2
Cauchi, S.3
-
40
-
-
34547831224
-
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals
-
Young EH, Wareham NJ, Farooqi S, et al. The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals. Int J Obes (Lond) 2007; 31: 1437-1441.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 1437-1441
-
-
Young, E.H.1
Wareham, N.J.2
Farooqi, S.3
-
41
-
-
77249140993
-
Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals
-
Wang D, Ma J, Zhang S, et al. Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55, 195 individuals. Obesity (Silver Spring) 2010; 18:573-579.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 573-579
-
-
Wang, D.1
Ma, J.2
Zhang, S.3
-
42
-
-
0027456619
-
Molecular cloning of a novel melanocortin receptor
-
Gantz I, Konda Y, Tashiro T, et al. Molecular cloning of a novel melanocortin receptor. J Biol Chem 1993; 268: 8246-8250.
-
(1993)
J Biol Chem
, vol.268
, pp. 8246-8250
-
-
Gantz, I.1
Konda, Y.2
Tashiro, T.3
-
43
-
-
0027436690
-
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
-
Roselli-Rehfuss L, Mountjoy KG, Robbins LS, et al. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc Natl Acad Sci U S A 1993; 90: 8856-8860.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8856-8860
-
-
Roselli-Rehfuss, L.1
Mountjoy, K.G.2
Robbins, L.S.3
-
45
-
-
0033977437
-
Melanocortin 3 receptor (MC3R) gene variants in extremely obese women
-
Li WD, Joo EJ, Furlong EB, et al. Melanocortin 3 receptor (MC3R) gene variants in extremely obese women. Int J Obes Relat Metab Disord 2000; 24: 206-210.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 206-210
-
-
Li, W.D.1
Joo, E.J.2
Furlong, E.B.3
-
46
-
-
0035380668
-
Naturally occurring mutations in the melanocortin receptor 3 gene are not associated with type 2 diabetes mellitus in French Caucasians
-
Hani EH, Dupont S, Durand E, et al. Naturally occurring mutations in the melanocortin receptor 3 gene are not associated with type 2 diabetes mellitus in French Caucasians. J Clin Endocrinol Metab 2001; 86: 2895-2898.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 2895-2898
-
-
Hani, E.H.1
Dupont, S.2
Durand, E.3
-
47
-
-
10244226787
-
The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908c/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek caucasians
-
Yiannakouris N, Melistas L, Kontogianni M, Heist K, Mantzoros CS. The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908c/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek caucasians. J Endocrinol Invest 2004; 27: 714-720.
-
(2004)
J Endocrinol Invest
, vol.27
, pp. 714-720
-
-
Yiannakouris, N.1
Melistas, L.2
Kontogianni, M.3
Heist, K.4
Mantzoros, C.S.5
-
48
-
-
78650553919
-
Rare melanocortin-3 receptor mutations with in vitro functional consequences are associated with human obesity
-
Mencarelli M, Dubern B, Alili R, et al. Rare melanocortin-3 receptor mutations with in vitro functional consequences are associated with human obesity. Hum Mol Genet 2011; 20: 392-399.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 392-399
-
-
Mencarelli, M.1
Dubern, B.2
Alili, R.3
-
49
-
-
61849161252
-
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study
-
Calton MA, Ersoy BA, Zhang S, et al. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet 2009; 18: 1140-1147.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1140-1147
-
-
Calton, M.A.1
Ersoy, B.A.2
Zhang, S.3
|