메뉴 건너뛰기




Volumn 34, Issue 3, 2012, Pages 895-904

Protective effect of lactofermented red beetroot juice against aberrant crypt foci formation, genotoxicity of fecal water and oxidative stress induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats model

Author keywords

Aberrant crypt foci; Betalain; Fermented beetroot juice; Functional food; Lactobacillus; Oxidative status

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CARCINOGEN; MALONALDEHYDE;

EID: 84871772359     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2012.08.009     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 51449109544 scopus 로고    scopus 로고
    • The past, present and future of multi-targeted cancer treatment "Naturally": food for thought
    • Aggarwal B.B. The past, present and future of multi-targeted cancer treatment "Naturally": food for thought. Cancer Lett. 2008, 269:187-188.
    • (2008) Cancer Lett. , vol.269 , pp. 187-188
    • Aggarwal, B.B.1
  • 2
    • 0025934809 scopus 로고
    • Formation of a glutathione conjugate and a semistable transportable glucuronide of N2-oxidized species of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat liver
    • Alexander J., Wallin H., Rossland O.J., Solberg K.E., Holme J.A., Becher G., Andersson R., Grivas S. Formation of a glutathione conjugate and a semistable transportable glucuronide of N2-oxidized species of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat liver. Carcinogenesis 1991, 12:2239-2245.
    • (1991) Carcinogenesis , vol.12 , pp. 2239-2245
    • Alexander, J.1    Wallin, H.2    Rossland, O.J.3    Solberg, K.E.4    Holme, J.A.5    Becher, G.6    Andersson, R.7    Grivas, S.8
  • 3
    • 0023629080 scopus 로고
    • Observation and quantification of aberrant crypts in murine colon treated with a colon carcinog preliminary findings
    • Bird R.P. Observation and quantification of aberrant crypts in murine colon treated with a colon carcinog preliminary findings. Cancer Lett. 1987, 37:147-151.
    • (1987) Cancer Lett. , vol.37 , pp. 147-151
    • Bird, R.P.1
  • 4
    • 0034699113 scopus 로고    scopus 로고
    • A comparison of the in vitro genotoxicity of tri-and hexavalent chromium
    • Błasiak J., Kowalik J. A comparison of the in vitro genotoxicity of tri-and hexavalent chromium. Mutat. Res. 2000, 649:135-145.
    • (2000) Mutat. Res. , vol.649 , pp. 135-145
    • Błasiak, J.1    Kowalik, J.2
  • 5
    • 0035711224 scopus 로고    scopus 로고
    • Effect of lactobacilli, bifidobacteria and inulin on the formation of aberrant crypt foci in rats
    • Bolognani F., Rumney C.J., Pool-Zobel B.L., Rowland I.R. Effect of lactobacilli, bifidobacteria and inulin on the formation of aberrant crypt foci in rats. Eur. J. Nutr. 2001, 40:293-300.
    • (2001) Eur. J. Nutr. , vol.40 , pp. 293-300
    • Bolognani, F.1    Rumney, C.J.2    Pool-Zobel, B.L.3    Rowland, I.R.4
  • 7
    • 33947188192 scopus 로고    scopus 로고
    • Differences between the faecal microbiota of celiac children and healthy controls
    • Collado M., Calabuing M., Sanz Y. Differences between the faecal microbiota of celiac children and healthy controls. Curr. Issues Intest. Microbiol. 2007, 8:9-14.
    • (2007) Curr. Issues Intest. Microbiol. , vol.8 , pp. 9-14
    • Collado, M.1    Calabuing, M.2    Sanz, Y.3
  • 8
    • 33645979676 scopus 로고    scopus 로고
    • The influence of lactic acid fermentation process of red beet juice on the stability of biologically active colorants
    • Czyzowska A., Klewicka E., Libudzisz Z. The influence of lactic acid fermentation process of red beet juice on the stability of biologically active colorants. Eur. Food Res. Technol. 2006, 223:110-116.
    • (2006) Eur. Food Res. Technol. , vol.223 , pp. 110-116
    • Czyzowska, A.1    Klewicka, E.2    Libudzisz, Z.3
  • 9
    • 69749125001 scopus 로고    scopus 로고
    • Gastrointestinal microflora, food components and colon cancer prevention
    • Davis C.D., Milner J.A. Gastrointestinal microflora, food components and colon cancer prevention. J. Nutr. Biochem. 2009, 20:743-752.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 743-752
    • Davis, C.D.1    Milner, J.A.2
  • 11
    • 0036086130 scopus 로고    scopus 로고
    • Free radical in the physiological control of cell function
    • Droge W. Free radical in the physiological control of cell function. Physiol. Rev. 2002, 82:47-95.
    • (2002) Physiol. Rev. , vol.82 , pp. 47-95
    • Droge, W.1
  • 12
    • 77956172547 scopus 로고    scopus 로고
    • Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ)
    • Ferk F., Huber W.W., Filipič M., Bichler J., Haslinger E., Mišik M., Nersesyan A., Grasal-Kraupp B., Žegura B., Knasmüller S. Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ). Mutat. Res. 2010, 691:17-22.
    • (2010) Mutat. Res. , vol.691 , pp. 17-22
    • Ferk, F.1    Huber, W.W.2    Filipič, M.3    Bichler, J.4    Haslinger, E.5    Mišik, M.6    Nersesyan, A.7    Grasal-Kraupp, B.8    Žegura, B.9    Knasmüller, S.10
  • 14
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., Reed J.C. Mitochondria and apoptosis. Science 1998, 281(28):1309-1312.
    • (1998) Science , vol.281 , Issue.28 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 15
    • 0031555339 scopus 로고    scopus 로고
    • Protective effect of carnosine against malonodialdehyde -induced toxicity towards cultured brain endothelial cells
    • Hipkiss A.R., Preston J.E., Himswoth D.M., Worthington V.C., Abbot N.J. Protective effect of carnosine against malonodialdehyde -induced toxicity towards cultured brain endothelial cells. Neurosci. Lett. 1997, 238:135-138.
    • (1997) Neurosci. Lett. , vol.238 , pp. 135-138
    • Hipkiss, A.R.1    Preston, J.E.2    Himswoth, D.M.3    Worthington, V.C.4    Abbot, N.J.5
  • 16
    • 0032782895 scopus 로고    scopus 로고
    • Development and validation of automated microscopy-based method for enumeration of groups of intestinal bacteria
    • Jansen G.J., Wildeboer-Veloo A.C.M., Tonk R.H.J., Franks A.H., Welling G.W. Development and validation of automated microscopy-based method for enumeration of groups of intestinal bacteria. J. Microbiol. Meth. 1999, 37:215-221.
    • (1999) J. Microbiol. Meth. , vol.37 , pp. 215-221
    • Jansen, G.J.1    Wildeboer-Veloo, A.C.M.2    Tonk, R.H.J.3    Franks, A.H.4    Welling, G.W.5
  • 17
    • 0035181508 scopus 로고    scopus 로고
    • Betalains -a new class of dietary cationized antioxidants
    • Kanner J., Harel S., Granit R. Betalains -a new class of dietary cationized antioxidants. J. Agric. Food Chem. 2001, 49:5178-5185.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 5178-5185
    • Kanner, J.1    Harel, S.2    Granit, R.3
  • 18
    • 0037331663 scopus 로고    scopus 로고
    • Chemoprevention of DMBA-induced UV-B promoted. NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot
    • Kapadia G.J., Azuine M.A., Sridhar R., Okuda Y., Tsuruta A., Ichiishi E., Mukainake T., Takasaki M., Konoshima T., Nishino H., Tokuda H. Chemoprevention of DMBA-induced UV-B promoted. NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot. Pharm. Res. 2003, 47:141-148.
    • (2003) Pharm. Res. , vol.47 , pp. 141-148
    • Kapadia, G.J.1    Azuine, M.A.2    Sridhar, R.3    Okuda, Y.4    Tsuruta, A.5    Ichiishi, E.6    Mukainake, T.7    Takasaki, M.8    Konoshima, T.9    Nishino, H.10    Tokuda, H.11
  • 19
    • 33748349879 scopus 로고    scopus 로고
    • A vegetable to meat consumption ratio as relevant factor determining cancer preventive diet. The Mediterranean versus other European countries
    • Forum Nurt. Basel. S. Karger, Basel, M. Heinrich, W.E. Müller, C. Galli (Eds.)
    • Kapiszewska M. A vegetable to meat consumption ratio as relevant factor determining cancer preventive diet. The Mediterranean versus other European countries. Local Mediterranean Food Plants and Nutraceuticals 2006, 130-153. Forum Nurt. Basel. S. Karger, Basel. M. Heinrich, W.E. Müller, C. Galli (Eds.).
    • (2006) Local Mediterranean Food Plants and Nutraceuticals , pp. 130-153
    • Kapiszewska, M.1
  • 20
    • 0030580947 scopus 로고    scopus 로고
    • The comet assay: mechanisms and technical consideration
    • Klaude M., Eriksson S., Nygren J., Ahnstrom G. The comet assay: mechanisms and technical consideration. Mutat. Res. 1996, 363:89-96.
    • (1996) Mutat. Res. , vol.363 , pp. 89-96
    • Klaude, M.1    Eriksson, S.2    Nygren, J.3    Ahnstrom, G.4
  • 21
    • 84863631171 scopus 로고    scopus 로고
    • Betacyanins -bioavailability and biological activity
    • (in Polish; abstract in English)
    • Klewicka E. Betacyanins -bioavailability and biological activity. zywność Nauka Technologia Jakość 2012, 2(81):5-21. (in Polish; abstract in English).
    • (2012) zywność Nauka Technologia Jakość , vol.2 , Issue.81 , pp. 5-21
    • Klewicka, E.1
  • 22
    • 77955028107 scopus 로고    scopus 로고
    • Fermented beetroot juice as a factor limiting chemical mutations induced by MNNG in the Salmonella typhimurium TA 98 and TA 100 strains
    • Klewicka E. Fermented beetroot juice as a factor limiting chemical mutations induced by MNNG in the Salmonella typhimurium TA 98 and TA 100 strains. Food Technol. Biotechnol. 2010, 48(2):229-233.
    • (2010) Food Technol. Biotechnol. , vol.48 , Issue.2 , pp. 229-233
    • Klewicka, E.1
  • 23
    • 80053483200 scopus 로고    scopus 로고
    • The biological stability of lacto-fermented beetroot juice during refrigerated storage
    • Klewicka E., Czyzowska A. The biological stability of lacto-fermented beetroot juice during refrigerated storage. Pol. J. Food Sci. Nutr. 2011, 61(4):251-256.
    • (2011) Pol. J. Food Sci. Nutr. , vol.61 , Issue.4 , pp. 251-256
    • Klewicka, E.1    Czyzowska, A.2
  • 24
    • 64949170214 scopus 로고    scopus 로고
    • Effect of lactobacillus fermented beetroot juice on composition and activity of cecal microflora of rats
    • Klewicka E., Zduńczyk Z., Juśkiewicz J. Effect of lactobacillus fermented beetroot juice on composition and activity of cecal microflora of rats. Eur. Food Res. Technol. 2009, 229:153-157.
    • (2009) Eur. Food Res. Technol. , vol.229 , pp. 153-157
    • Klewicka, E.1    Zduńczyk, Z.2    Juśkiewicz, J.3
  • 26
    • 0028342393 scopus 로고
    • Determination of proanthocyanidins and catechins in beer and barley by high-performance liquid chromatography with dual-electrode electrochemical detection
    • Madigan D., McMurrough I., Smyth M.R. Determination of proanthocyanidins and catechins in beer and barley by high-performance liquid chromatography with dual-electrode electrochemical detection. Analyst 1994, 119:863-868.
    • (1994) Analyst , vol.119 , pp. 863-868
    • Madigan, D.1    McMurrough, I.2    Smyth, M.R.3
  • 27
    • 70349604811 scopus 로고    scopus 로고
    • Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro
    • Nowak A., Libudzisz Z. Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro. Eur. J. Nutr. 2009, 48:419-427.
    • (2009) Eur. J. Nutr. , vol.48 , pp. 419-427
    • Nowak, A.1    Libudzisz, Z.2
  • 28
    • 84871247698 scopus 로고    scopus 로고
    • Carcinogenic activity of intestinal microbiota
    • (in Polish; abstract in English)
    • Nowak A., Libudzisz Z. Carcinogenic activity of intestinal microbiota. zywność Nauka Technologia Jakość 2008, 6(61):25-39. (in Polish; abstract in English).
    • (2008) zywność Nauka Technologia Jakość , vol.6 , Issue.61 , pp. 25-39
    • Nowak, A.1    Libudzisz, Z.2
  • 29
    • 1842579604 scopus 로고    scopus 로고
    • Inhibitory effects of beer on heterocyclic amine-induced mutagenesis and PhIP -induced aberrant crypt foci in rat colon
    • Nozawa H., Tazumi K., Sato K., Yoshida A., Takata J., Arimoto-Kobayashi S., Kondo K. Inhibitory effects of beer on heterocyclic amine-induced mutagenesis and PhIP -induced aberrant crypt foci in rat colon. Mutat. Res. 2004, 559:177-187.
    • (2004) Mutat. Res. , vol.559 , pp. 177-187
    • Nozawa, H.1    Tazumi, K.2    Sato, K.3    Yoshida, A.4    Takata, J.5    Arimoto-Kobayashi, S.6    Kondo, K.7
  • 30
    • 36549075219 scopus 로고    scopus 로고
    • Nutrition and colonic health: the critical role of the microbiota
    • O'Keefe S.J. Nutrition and colonic health: the critical role of the microbiota. Curr. Opin. Gastroenterol. 2008, 24:51-58.
    • (2008) Curr. Opin. Gastroenterol. , vol.24 , pp. 51-58
    • O'Keefe, S.J.1
  • 31
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 32
    • 78549258809 scopus 로고    scopus 로고
    • Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed in immortal mammalian cells
    • Platt K.L., Edenharder R., Aderhold S., Muckel E., Glatt H. Fruits and vegetables protect against the genotoxicity of heterocyclic aromatic amines activated by human xenobiotic-metabolizing enzymes expressed in immortal mammalian cells. Mutat. Res. 2010, 703:90-98.
    • (2010) Mutat. Res. , vol.703 , pp. 90-98
    • Platt, K.L.1    Edenharder, R.2    Aderhold, S.3    Muckel, E.4    Glatt, H.5
  • 33
    • 0036288062 scopus 로고    scopus 로고
    • Experimental evidences on the potential of probiotic fructans to reduce the risk of colon cancer
    • Pool-Zobel B., Van Loo J., Rowland I., Reberfroid M.B. Experimental evidences on the potential of probiotic fructans to reduce the risk of colon cancer. Br. J. Nutr. 2002, 87:273-281.
    • (2002) Br. J. Nutr. , vol.87 , pp. 273-281
    • Pool-Zobel, B.1    Van Loo, J.2    Rowland, I.3    Reberfroid, M.B.4
  • 34
    • 79951773045 scopus 로고    scopus 로고
    • Heterocyclic amine content in commercial ready to eat meat products
    • Puangsombat K., Gadil P., Houser A.T., Hunt C.M., Smith J.S. Heterocyclic amine content in commercial ready to eat meat products. Meat Sci. 2011, 88:227-233.
    • (2011) Meat Sci. , vol.88 , pp. 227-233
    • Puangsombat, K.1    Gadil, P.2    Houser, A.T.3    Hunt, C.M.4    Smith, J.S.5
  • 35
    • 0030912476 scopus 로고    scopus 로고
    • Components of the AIN-93 diets as improvements in the AIN-76A
    • Reeves P.G. Components of the AIN-93 diets as improvements in the AIN-76A. J. Nutr. 1997, 127:S838-S841.
    • (1997) J. Nutr. , vol.127
    • Reeves, P.G.1
  • 36
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175:184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.2    Tice, R.R.3    Schneider, E.L.4
  • 37
    • 0028850262 scopus 로고
    • High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) occur in chicen but are dependent on the cooking method
    • Sinha R., Rothman N., Brown E.D., Salmon C.P., Knize M.G., Swanson C.A., Rossi S.C., Mark S.D., Levander O.A., Felton J.S. High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) occur in chicen but are dependent on the cooking method. Cancer Res. 1995, 55:4516-4519.
    • (1995) Cancer Res. , vol.55 , pp. 4516-4519
    • Sinha, R.1    Rothman, N.2    Brown, E.D.3    Salmon, C.P.4    Knize, M.G.5    Swanson, C.A.6    Rossi, S.C.7    Mark, S.D.8    Levander, O.A.9    Felton, J.S.10
  • 38
    • 35148837739 scopus 로고    scopus 로고
    • Betanin a betacyanin pigment purified from fruits of Opuntia ficus-indica induces apoptosis in human chronic myeloid leukemia cell line K562
    • Sreekanth D., Arunasree M.K., Roy K.R., Reddy T.Ch., Reddy G.V., Reddanna P. Betanin a betacyanin pigment purified from fruits of Opuntia ficus-indica induces apoptosis in human chronic myeloid leukemia cell line K562. Phytomedicine 2007, 14:739-746.
    • (2007) Phytomedicine , vol.14 , pp. 739-746
    • Sreekanth, D.1    Arunasree, M.K.2    Roy, K.R.3    Reddy, T.4    Reddy, G.V.5    Reddanna, P.6
  • 39
    • 41949113893 scopus 로고    scopus 로고
    • Binding of heterocyclic aromatic amines by lactic acid bacteria: results of comprehensive screening trial
    • Stidl R., Sontag G., Koller V., Knasmüller S. Binding of heterocyclic aromatic amines by lactic acid bacteria: results of comprehensive screening trial. Mol. Nutr. Food Res. 2008, 52:322-329.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 322-329
    • Stidl, R.1    Sontag, G.2    Koller, V.3    Knasmüller, S.4
  • 41
    • 33846419107 scopus 로고    scopus 로고
    • Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion
    • Tache S., Ladam A., Corpet D.E. Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion. Eur. J. Cancer. 2007, 43:454-458.
    • (2007) Eur. J. Cancer. , vol.43 , pp. 454-458
    • Tache, S.1    Ladam, A.2    Corpet, D.E.3
  • 42
    • 40749103351 scopus 로고    scopus 로고
    • The physiological relevance of the intestinal microbiota -contributions to human health
    • Tappenden K.A., Deutsch A.S. The physiological relevance of the intestinal microbiota -contributions to human health. J. Am. Coll. Nutr. 2007, 26:79s-83s.
    • (2007) J. Am. Coll. Nutr. , vol.26
    • Tappenden, K.A.1    Deutsch, A.S.2
  • 43
    • 5144227379 scopus 로고    scopus 로고
    • Absorption, extraction and distribution of dietary antioxidant betalains in LDLs: potential health effects of betalains in human
    • Tesoriere L., Allegra M., Butera D., Livrea M.A. Absorption, extraction and distribution of dietary antioxidant betalains in LDLs: potential health effects of betalains in human. Am. J. Clin. Nutr. 2004, 80:941-945.
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 941-945
    • Tesoriere, L.1    Allegra, M.2    Butera, D.3    Livrea, M.A.4
  • 45
    • 33846829596 scopus 로고    scopus 로고
    • Heterocyclic amines in griddled beef steak analyzed using single extract clean-up procedure
    • Toribio F., Busquets R., Puignou L., Galeran M.T. Heterocyclic amines in griddled beef steak analyzed using single extract clean-up procedure. Food Chem. Toxicol. 2007, 45:667-675.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 667-675
    • Toribio, F.1    Busquets, R.2    Puignou, L.3    Galeran, M.T.4
  • 46
    • 0036041273 scopus 로고    scopus 로고
    • Heterocyclic aromatic amine metabolism. DNA adduct formation, mutagenesis, and carcinogenesis
    • Turesky R.J. Heterocyclic aromatic amine metabolism. DNA adduct formation, mutagenesis, and carcinogenesis. Drug Metab. Rev. 2002, 34:625-650.
    • (2002) Drug Metab. Rev. , vol.34 , pp. 625-650
    • Turesky, R.J.1
  • 47
    • 84871785718 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services Report on Carcinogens. Public Health Service, National Toxicology Program
    • U.S. Department of Health and Human Services Report on Carcinogens 2005, Public Health Service, National Toxicology Program. 11th ed.
    • (2005)
  • 48
    • 41949093540 scopus 로고    scopus 로고
    • The microbial PhIP metaboloite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-α] pyrimidin-5-ium chloride (PhIP-M1) induced DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells
    • Vanhaecke L., Derycke L., Le Curieux F., Lust S., Marzin D., Verstraete W., Bracke M. The microbial PhIP metaboloite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-α] pyrimidin-5-ium chloride (PhIP-M1) induced DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells. Toxicol. Lett. 2008, 178:61-69.
    • (2008) Toxicol. Lett. , vol.178 , pp. 61-69
    • Vanhaecke, L.1    Derycke, L.2    Le Curieux, F.3    Lust, S.4    Marzin, D.5    Verstraete, W.6    Bracke, M.7
  • 49
    • 0036716803 scopus 로고    scopus 로고
    • Dietary inulin suppresses azoxymethane-induced preneoplastic aberrant crypt foci in mature fisher 344 rats
    • Verghese M., Rao D.R., Chawan C.B., Shackelford L. Dietary inulin suppresses azoxymethane-induced preneoplastic aberrant crypt foci in mature fisher 344 rats. J. Nutr. 2002, 132:2804-2808.
    • (2002) J. Nutr. , vol.132 , pp. 2804-2808
    • Verghese, M.1    Rao, D.R.2    Chawan, C.B.3    Shackelford, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.