LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

EMBO Journal

Volumn 31, Issue 2, 2012, Pages 443-456

  Ruzzenente, Benedetta ^a,b   Metodiev, Metodi D ^a   Wredenberg, Anna ^a   Bratic, Ana ^a,c   Park, Chan Bae ^d   Cámara, Yolanda ^e,f   Milenkovic, Dusanka ^a   Zickermann, Volker ^g   Wibom, Rolf ^c   Hultenby, Kjell ^c   Erdjument Bromage, Hediye ^h   Tempst, Paul ^h   Brandt, Ulrich ^g   Stewart, James B ^a   Gustafsson, Claes M ⁱ   Larsson, Nils Göran ^a,c  

^a MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

^b UNIVERSITY OF PADOVA   (Italy)

^c KAROLINSKA INSTITUTE   (Sweden)

^d Ajou University School of Medicine   (South Korea)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^g GOETHE UNIVERSITY   (Germany)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Leigh syndrome French Canadian variant; LRPPRC; mitochondria; RNA stability; SLIRP

Indexed keywords

LEUCINE RICH PENTATRICOPEPTIDE REPEAT CONTAINING PROTEIN; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; CYTOCHROME C OXIDASE DEFICIENCY; EMBRYO; EMBRYO DEVELOPMENT; MAMMAL CELL; MOUSE; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN DEPLETION; STEADY STATE; TRANSLATION REGULATION;

ANIMALS; CYTOCHROME-C OXIDASE DEFICIENCY; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; HELA CELLS; HUMANS; LEIGH DISEASE; MACROMOLECULAR SUBSTANCES; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; NEOPLASM PROTEINS; ORGAN SPECIFICITY; POLYADENYLATION; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS;

MAMMALIA; MUS;

EID: 84857192195     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.392     Document Type: Article

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