-
1
-
-
75149130955
-
Diagnosis and classification of diabetes mellitus
-
American Diabetes Association
-
American Diabetes Association. Diagnosis and classification of diabetes mellitus Diabetes Care 2010;33(1):S62-9.
-
(2010)
Diabetes Care
, vol.33
, Issue.1
-
-
-
2
-
-
77951776390
-
Genetic, pathogenesis and clinical intervention in type 1 diabetes
-
J.A. Bluestone, K. Herold, and G. Eisenbarth Genetic, pathogenesis and clinical intervention in type 1 diabetes Nature 464 7293 2010 1293 1300
-
(2010)
Nature
, vol.464
, Issue.7293
, pp. 1293-1300
-
-
Bluestone, J.A.1
Herold, K.2
Eisenbarth, G.3
-
3
-
-
36849089218
-
The vicious cycle of apoptotic β-cell death in type 1 diabetes
-
A. Kaminitz, J. Stein, I. Yaniv, and N. Askenasy The vicious cycle of apoptotic β-cell death in type 1 diabetes Immunol Cell Biol 85 8 2007 582 589
-
(2007)
Immunol Cell Biol
, vol.85
, Issue.8
, pp. 582-589
-
-
Kaminitz, A.1
Stein, J.2
Yaniv, I.3
Askenasy, N.4
-
4
-
-
33745316621
-
Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines
-
J.J. Collier, P.T. Fueger, H.E. Hohmeier, and C.B. Newgard Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines Diabetes 55 5 2006 1398 1406
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1398-1406
-
-
Collier, J.J.1
Fueger, P.T.2
Hohmeier, H.E.3
Newgard, C.B.4
-
5
-
-
84860488264
-
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction
-
J.R. Weaver, T.R. Holman, Y. Imai, A. Jadhav, V. Kenyon, and D.J. Maloney Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction Mol Cell Endocrinol 358 1 2012 88 95
-
(2012)
Mol Cell Endocrinol
, vol.358
, Issue.1
, pp. 88-95
-
-
Weaver, J.R.1
Holman, T.R.2
Imai, Y.3
Jadhav, A.4
Kenyon, V.5
Maloney, D.J.6
-
6
-
-
0041828484
-
Inflammatory mediators and islet β-cell failure: A link between type i and type II diabetes
-
M.Y. Donath, J. Storling, K. Maedler, and T. Mandrup-Poulson Inflammatory mediators and islet β-cell failure: a link between type I and type II diabetes J Mol Med 81 8 2003 455 470
-
(2003)
J Mol Med
, vol.81
, Issue.8
, pp. 455-470
-
-
Donath, M.Y.1
Storling, J.2
Maedler, K.3
Mandrup-Poulson, T.4
-
7
-
-
80052492726
-
Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria
-
E. Gurgul-Convey, I. Mehmeti, S. Lortz, and S. Lenzen Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria J Mol Med 89 8 2011 785 798
-
(2011)
J Mol Med
, vol.89
, Issue.8
, pp. 785-798
-
-
Gurgul-Convey, E.1
Mehmeti, I.2
Lortz, S.3
Lenzen, S.4
-
8
-
-
0035584412
-
Positive modulation by Ras of interleukin-1β-mediated nitric oxide generation in insulin-secreting clonal β (HIT-T15) cells
-
M. Tannous, R. Amin, M.R. Popoff, C. Fiorentini, and A. Kowluru Positive modulation by Ras of interleukin-1β-mediated nitric oxide generation in insulin-secreting clonal β (HIT-T15) cells Biochem Pharmacol 62 11 2001 1459 1468
-
(2001)
Biochem Pharmacol
, vol.62
, Issue.11
, pp. 1459-1468
-
-
Tannous, M.1
Amin, R.2
Popoff, M.R.3
Fiorentini, C.4
Kowluru, A.5
-
9
-
-
0030985959
-
Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production
-
M. Flodström, and D.L. Eizirik Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production Endocrinology 138 7 1997 2747 2753
-
(1997)
Endocrinology
, vol.138
, Issue.7
, pp. 2747-2753
-
-
Flodström, M.1
Eizirik, D.L.2
-
10
-
-
79251492010
-
NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets
-
M.F.R. Graciano, L.R.B. Santos, R. Curi, and A.R. Carpinelli NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets J Cell Physiol 226 4 2011 1110 1117
-
(2011)
J Cell Physiol
, vol.226
, Issue.4
, pp. 1110-1117
-
-
Graciano, M.F.R.1
Santos, L.R.B.2
Curi, R.3
Carpinelli, A.R.4
-
12
-
-
70949087785
-
Insights in to the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic β-cell
-
P. Newsholme, D. Morgan, E. Rebelato, H.C. Oliveira-Emilio, J. Procopio, and R. Curi Insights in to the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic β-cell Diabetologia 52 12 2009 2489 2498
-
(2009)
Diabetologia
, vol.52
, Issue.12
, pp. 2489-2498
-
-
Newsholme, P.1
Morgan, D.2
Rebelato, E.3
Oliveira-Emilio, H.C.4
Procopio, J.5
Curi, R.6
-
13
-
-
0037645789
-
Pancreatic β-cells express phagocyte like NADPH oxidase
-
H.R. Oliveira, R. Verlengia, C.R. Carvalho, L.R. Britto, R. Curi, and A.R. Carpinelli Pancreatic β-cells express phagocyte like NADPH oxidase Diabetes 52 6 2003 1457 1463
-
(2003)
Diabetes
, vol.52
, Issue.6
, pp. 1457-1463
-
-
Oliveira, H.R.1
Verlengia, R.2
Carvalho, C.R.3
Britto, L.R.4
Curi, R.5
Carpinelli, A.R.6
-
14
-
-
78650665214
-
Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: Evidence for regulation by Rac1
-
W. Subasinghe, I. Syed, and A. Kowluru Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1 Am J Physiol Regul Integr Comp Physiol 300 1 2011 R12 R20
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
, Issue.1
-
-
Subasinghe, W.1
Syed, I.2
Kowluru, A.3
-
15
-
-
77954760363
-
Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxide and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic β-cells
-
I. Syed, B. Jayaram, W. Subasinghe, and A. Kowluru Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxide and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic β-cells Biochem Pharmacol 80 6 2010 874 883
-
(2010)
Biochem Pharmacol
, vol.80
, Issue.6
, pp. 874-883
-
-
Syed, I.1
Jayaram, B.2
Subasinghe, W.3
Kowluru, A.4
-
16
-
-
79952780609
-
Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: Role of protein prenylation
-
I. Syed, C.N. Kyathanahalli, and A. Kowluru Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation Am J Physiol Regul Integr Comp Physiol 300 3 2011 R756 R762
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
, Issue.3
-
-
Syed, I.1
Kyathanahalli, C.N.2
Kowluru, A.3
-
17
-
-
78650639425
-
Unraveling the molecular machinery that promotes pancreatic β-cell dysfunction during oxidative stress: Focus on phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: Evidence for regulation by Rac1
-
M. Jastroch Unraveling the molecular machinery that promotes pancreatic β-cell dysfunction during oxidative stress: focus on phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1 Am J Physiol Regul Integr Comp Physiol 300 1 2011 R9 R11
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
, Issue.1
-
-
Jastroch, M.1
-
18
-
-
79251550763
-
Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: Role of PKCζ-mediated p47phox phosphorylation
-
J.T. Leverence, M. Medhora, G.G. Konduri, and V. Sampath Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation Chem Biol Interact 189 1-2 2011 72 81
-
(2011)
Chem Biol Interact
, vol.189
, Issue.12
, pp. 72-81
-
-
Leverence, J.T.1
Medhora, M.2
Konduri, G.G.3
Sampath, V.4
-
19
-
-
14844349754
-
Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: Role of p47phox phosphorylation and binding to TRAF4
-
J.M. Li, L.M. Fan, M.R. Christie, and A.M. Shahi Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4 Mol Cell Biol 25 6 2005 2320 2330
-
(2005)
Mol Cell Biol
, vol.25
, Issue.6
, pp. 2320-2330
-
-
Li, J.M.1
Fan, L.M.2
Christie, M.R.3
Shahi, A.M.4
-
20
-
-
24344453811
-
Synergistic activation of JNK/SAPK induced by TNF-α and IFN-γ: Apoptosis of pancreatic β-cells via the p53 and ROS pathway
-
W.H. Kim, J.W. Lee, B. Goa, and M.H. Jung Synergistic activation of JNK/SAPK induced by TNF-α and IFN-γ: apoptosis of pancreatic β-cells via the p53 and ROS pathway Cell Signal 17 12 2005 1516 1532
-
(2005)
Cell Signal
, vol.17
, Issue.12
, pp. 1516-1532
-
-
Kim, W.H.1
Lee, J.W.2
Goa, B.3
Jung, M.H.4
-
21
-
-
76149107841
-
Small G proteins in islet β function
-
A. Kowluru Small G proteins in islet β function Endocr Rev 31 1 2010 52 78
-
(2010)
Endocr Rev
, vol.31
, Issue.1
, pp. 52-78
-
-
Kowluru, A.1
-
22
-
-
0035208918
-
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells
-
J.R. Lakey, W.L. Suarez-Pinzon, K. Strynadka, G.S. Korbutt, R.V. Rajotte, and J.G. Mabley Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells Lab Invest 81 12 2001 1683 1692
-
(2001)
Lab Invest
, vol.81
, Issue.12
, pp. 1683-1692
-
-
Lakey, J.R.1
Suarez-Pinzon, W.L.2
Strynadka, K.3
Korbutt, G.S.4
Rajotte, R.V.5
Mabley, J.G.6
-
23
-
-
80054716803
-
Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway
-
Z. Zhang, Y. Ding, X. Dai, J. Wang, and Y. Li Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway Eur J Pharmacol 670 1 2011 311 316
-
(2011)
Eur J Pharmacol
, vol.670
, Issue.1
, pp. 311-316
-
-
Zhang, Z.1
Ding, Y.2
Dai, X.3
Wang, J.4
Li, Y.5
-
24
-
-
0141888306
-
Novel roles for palmitoylation of Ras in IL-1β-induced nitric oxide release and caspase-3 activation in insulin-secreting β-cells
-
H.Q. Chen, M. Tannous, R. Veluthakal, R. Amin, and A. Kowluru Novel roles for palmitoylation of Ras in IL-1β-induced nitric oxide release and caspase-3 activation in insulin-secreting β-cells Biochem Pharmacol 66 9 2003 1681 1694
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.9
, pp. 1681-1694
-
-
Chen, H.Q.1
Tannous, M.2
Veluthakal, R.3
Amin, R.4
Kowluru, A.5
-
25
-
-
39149104320
-
The role of endoplasmic reticulum stress in diabetes mellitus
-
D.L. Eizirik, A.K. Cardozo, and M. Cnop The role of endoplasmic reticulum stress in diabetes mellitus Endocr Rev 29 1 2008 42 61
-
(2008)
Endocr Rev
, vol.29
, Issue.1
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
26
-
-
79959897450
-
Endoplasmic reticulum stress and pancreatic β-cell death
-
S.G. Fonseca, J. Gromada, and F. Urano Endoplasmic reticulum stress and pancreatic β-cell death TEM 22 7 2011 266 274
-
(2011)
TEM
, vol.22
, Issue.7
, pp. 266-274
-
-
Fonseca, S.G.1
Gromada, J.2
Urano, F.3
-
27
-
-
79959551995
-
Differential effects of proinflammatory cytokines on cell death and ER stress in insulin-secreting INS1E cells and the involvement of nitric oxide
-
S. Kacheva, S. Lenzen, and E. Gurgul-Concey Differential effects of proinflammatory cytokines on cell death and ER stress in insulin-secreting INS1E cells and the involvement of nitric oxide Cytokine 55 2 2011 195 201
-
(2011)
Cytokine
, vol.55
, Issue.2
, pp. 195-201
-
-
Kacheva, S.1
Lenzen, S.2
Gurgul-Concey, E.3
-
28
-
-
84861910718
-
A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death
-
A.C. Baldwin, C.D. Green, L.K. Olson, M.A. Moxley, and J.A. Corbett A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death Am J Physiol Endocrinol Metab 302 11 2012 E1390 E1398
-
(2012)
Am J Physiol Endocrinol Metab
, vol.302
, Issue.11
-
-
Baldwin, A.C.1
Green, C.D.2
Olson, L.K.3
Moxley, M.A.4
Corbett, J.A.5
-
29
-
-
80755184724
-
Increased phagocyte-like NADPH oxidase and reactive oxygen species generation in type 2 diabetic ZDF rat and human islets: Role of Rac1-Jun NH2- terminal kinase 1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet
-
I. Syed, C.N. Kyathanahalli, B. Jayaram, S. Govind, C.J. Rhodes, and R.A. Kowluru Increased phagocyte-like NADPH oxidase and reactive oxygen species generation in type 2 diabetic ZDF rat and human islets: role of Rac1-Jun NH2- terminal kinase 1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet Diabetes 60 11 2011 2843 2852
-
(2011)
Diabetes
, vol.60
, Issue.11
, pp. 2843-2852
-
-
Syed, I.1
Kyathanahalli, C.N.2
Jayaram, B.3
Govind, S.4
Rhodes, C.J.5
Kowluru, R.A.6
-
30
-
-
84862753776
-
A palmitoylation switch mechanism regulates Rac1 function and membrane organization
-
I. Navarro-Lerida, S. Sanchez-Perales, M. Calvo, C. Rentero, Y. Zheng, and C. Enrich A palmitoylation switch mechanism regulates Rac1 function and membrane organization EMBO J 31 3 2011 534 551
-
(2011)
EMBO J
, vol.31
, Issue.3
, pp. 534-551
-
-
Navarro-Lerida, I.1
Sanchez-Perales, S.2
Calvo, M.3
Rentero, C.4
Zheng, Y.5
Enrich, C.6
-
31
-
-
0037087639
-
GTP-binding proteins in cell survival and demise: The emerging pictures in pancreatic β-cell
-
A. Kowluru, and N.G. Morgan GTP-binding proteins in cell survival and demise: the emerging pictures in pancreatic β-cell Biochem Pharmacol 63 6 2002 1027 1035
-
(2002)
Biochem Pharmacol
, vol.63
, Issue.6
, pp. 1027-1035
-
-
Kowluru, A.1
Morgan, N.G.2
|