Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 311-316

  Zhang, Zhaofeng ^a   Ding, Ye ^a   Dai, Xiaoqian ^a   Wang, Junbo ^a   Li, Yong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Epigallocatechin 3 gallate; Insulin producing cell; Mitochondrial pathway; Pro inflammatory cytokine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C; CYTOKINE; EPIGALLOCATECHIN GALLATE; GAMMA INTERFERON; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RECOMBINANT INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL DAMAGE; CELL FUNCTION; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN SYNTHESIS; INTRACELLULAR TRANSPORT; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RADIOIMMUNOASSAY; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; BCL-2-ASSOCIATED X PROTEIN; CATECHIN; CELL DEATH; CELL LINE; CYTOCHROMES C; CYTOKINES; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 80054716803     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.033     Document Type: Article

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