Functional screening of TLRs in human amniotic epithelial cells

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2766-2774

  Gillaux, Claire ^a   Méhats, Céline ^a   Vaiman, Daniel ^a   Cabrol, Dominique ^b   Breuiller Fouché, Michelle ^a  

^a INSTITUT COCHIN   (France)

^b Assistance Publique Hôpitaux de Paris ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN BAX; PROTEIN BCL 2; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9;

AMNION CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INDUCTION; EPITHELIUM CELL; FEMALE; FETUS; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

AMNION; BLOTTING, WESTERN; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; HUMANS; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTORS;

EID: 80052677599     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100217     Document Type: Article

References (57)

1. Goldenberg, R. L., J. F. Culhane, J. D. Iams, and R. Romero. 2008. Epidemiology and causes of preterm birth. Lancet 371: 75-84.
2. Brown, N. L., S. A. Alvi, M. G. Elder, P. R. Bennett, and M. H. Sullivan. 1998. A spontaneous induction of fetal membrane prostaglandin production precedes clinical labour. J. Endocrinol. 157: R1-R6. (Pubitemid 28238038)
3. Khan, A. H., R. J. Carson, and S. M. Nelson. 2008. Prostaglandins in labor - a translational approach. Front. Biosci. 13: 5794-5809.
4. Olson, D. M. 2003. The role of prostaglandins in the initiation of parturition. Best Pract. Res. Clin. Obstet. Gynaecol. 17: 717-730. (Pubitemid 37168291)
5. Fortunato, S. J., R. Menon, C. Bryant, and S. J. Lombardi. 2000. Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes. Am. J. Obstet. Gynecol. 182: 1468-1476. (Pubitemid 30437418)
6. Romero, R., J. Espinoza, J. P. Kusanovic, F. Gotsch, S. Hassan, O. Erez, T. Chaiworapongsa, and M. Mazor. 2006. The preterm parturition syndrome. BJOG 113(Suppl 3): 17-42. (Pubitemid 44934664)
7. Christiaens, I., D. B. Zaragoza, L. Guilbert, S. A. Robertson, B. F. Mitchell, and D. M. Olson. 2008. Inflammatory processes in preterm and term parturition. J. Reprod. Immunol. 79: 50-57.
8. Goldenberg, R. L., J. C. Hauth, and W. W. Andrews. 2000. Intrauterine infection and preterm delivery. N. Engl. J. Med. 342: 1500-1507. (Pubitemid 30318275)
9. Kim, M. J., R. Romero, M. T. Gervasi, J. S. Kim, W. Yoo, D. C. Lee, P. Mittal, O. Erez, J. P. Kusanovic, S. S. Hassan, and C. J. Kim. 2009. Widespread microbial invasion of the chorioamniotic membranes is a consequence and not a cause of intra-amniotic infection. Lab. Invest. 89: 924-936.
10. Kawai, T., and S. Akira. 2010. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11: 373-384.
11. Drexler, S. K., and B. M. Foxwell. 2010. The role of toll-like receptors in chronic inflammation. Int. J. Biochem. Cell Biol. 42: 506-518.
12. Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell 124: 783-801. (Pubitemid 43261452)
13. Barton, G. M., and R. Medzhitov. 2003. Toll-like receptor signaling pathways. Science 300: 1524-1525. (Pubitemid 36682871)
14. Nasu, K., and H. Narahara. 2010. Pattern recognition via the toll-like receptor system in the human female genital tract. Mediators Inflamm. 2010: 976024.
15. Thaxton, J. E., T. A. Nevers, and S. Sharma. 2010. TLR-mediated preterm birth in response to pathogenic agents. Infect. Dis. Obstet. Gynecol. 2010: 378472.
16. Patni, S., P. Flynn, L. P. Wynen, A. L. Seager, G. Morgan, J. O. White, and C. A. Thornton. 2007. An introduction to Toll-like receptors and their possible role in the initiation of labour. BJOG 114: 1326-1334. (Pubitemid 47609941)
17. Fazeli, A., C. Bruce, and D. O. Anumba. 2005. Characterization of Toll-like receptors in the female reproductive tract in humans. Hum. Reprod. 20: 1372-1378. (Pubitemid 40790266)
18. Gonzalez, J. M., H. Xu, E. Ofori, and M. A. Elovitz. 2007. Toll-like receptors in the uterus, cervix, and placenta: is pregnancy an immunosuppressed state? Am. J. Obstet. Gynecol. 197: 296.e1-6.
19. Patni, S., L. P. Wynen, A. L. Seager, G. Morgan, J. O. White, and C. A. Thornton. 2009. Expression and activity of Toll-like receptors 1-9 in the human term placenta and changes associated with labor at term. Biol. Reprod. 80: 243-248.
20. Abrahams, V. M., and G. Mor. 2005. Toll-like receptors and their role in the trophoblast. Placenta 26: 540-547. (Pubitemid 40916306)
21. Kim, Y. M., R. Romero, T. Chaiworapongsa, G. J. Kim, M. R. Kim, H. Kuivaniemi, G. Tromp, J. Espinoza, E. Bujold, V. M. Abrahams, and G. Mor. 2004. Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis. Am. J. Obstet. Gynecol. 191: 1346-1355. (Pubitemid 39421595)
22. Haddad, R., G. Tromp, H. Kuivaniemi, T. Chaiworapongsa, Y. M. Kim, M. Mazor, and R. Romero. 2006. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am. J. Obstet. Gynecol. 195: 394.e1-24.
23. Parry, S., and J. F. Strauss, III. 1998. Premature rupture of the fetal membranes. N. Engl. J. Med. 338: 663-670. (Pubitemid 28108437)
24. Casey, M. L., and P. C. MacDonald. 1996. Interstitial collagen synthesis and processing in human amnion: a property of the mesenchymal cells. Biol. Reprod. 55: 1253-1260. (Pubitemid 26398868)
25. Oger, S., C. Méhats, E. Dallot, D. Cabrol, and M. J. Leroy. 2005. Evidence for a role of phosphodiesterase 4 in lipopolysaccharide-stimulated prostaglandin E2 production and matrix metalloproteinase-9 activity in human amniochorionic membranes. J. Immunol. 174: 8082-8089. (Pubitemid 40806319)
26. Hart, K. M., A. J. Murphy, K. T. Barrett, C. R. Wira, P. M. Guyre, and P. A. Pioli. 2009. Functional expression of pattern recognition receptors in tissues of the human female reproductive tract. J. Reprod. Immunol. 80: 33-40.
27. Noguchi, T., T. Sado, K. Naruse, H. Shigetomi, A. Onogi, S. Haruta, R. Kawaguchi, A. Nagai, Y. Tanase, S. Yoshida, et al. 2010. Evidence for activation of Toll-like receptor and receptor for advanced glycation end products in preterm birth. Mediators Inflamm. 2010: 490406.
28. Klaffenbach, D., W. Rascher, M. Röllinghoff, J. Dötsch, U. Meissner, and M. Schnare. 2005. Regulation and signal transduction of toll-like receptors in human chorioncarcinoma cell lines. Am. J. Reprod. Immunol. 53: 77-84. (Pubitemid 40347597)
29. Rindsjö, E., U. Holmlund, E. Sverremark-Ekström, N. Papadogiannakis, and A. Scheynius. 2007. Toll-like receptor-2 expression in normal and pathologic human placenta. Hum. Pathol. 38: 468-473. (Pubitemid 46227536)
30. Ma, Y., G. Krikun, V. M. Abrahams, G. Mor, and S. Guller. 2007. Cell type-specific expression and function of toll-like receptors 2 and 4 in human placenta: implications in fetal infection. Placenta 28: 1024-1031. (Pubitemid 47355239)
31. Dulay, A. T., C. S. Buhimschi, G. Zhao, E. A. Oliver, A. Mbele, S. Jing, and I. A. Buhimschi. 2009. Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection. J. Immunol. 182: 7244-7253.
32. Lappas, M., M. Permezel, H. M. Georgiou, and G. E. Rice. 2002. Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro. Biol. Reprod. 67: 668-673. (Pubitemid 34803959)
33. Allport, V. C., D. M. Slater, R. Newton, and P. R. Bennett. 2000. NF-kappaB and AP-1 are required for cyclo-oxygenase 2 gene expression in amnion epithelial cell line (WISH). Mol. Hum. Reprod. 6: 561-565. (Pubitemid 30365803)
34. Yan, X., M. Sun, and W. Gibb. 2002. Localization of nuclear factor-kappa B (NF kappa B) and inhibitory factor-kappa B (I kappa B) in human fetal membranes and decidua at term and preterm delivery. Placenta 23: 288-293. (Pubitemid 41348521)
35. Elliott, C. L., V. C. Allport, J. A. Loudon, G. D. Wu, and P. R. Bennett. 2001. Nuclear factor-kappa B is essential for up-regulation of interleukin-8 expression in human amnion and cervical epithelial cells. Mol. Hum. Reprod. 7: 787-790. (Pubitemid 32734303)
36. Romero, R., M. Emamian, M. Wan, R. Quintero, J. C. Hobbins, and M. D. Mitchell. 1987. Prostaglandin concentrations in amniotic fluid of women with intra-amniotic infection and preterm labor. Am. J. Obstet. Gynecol. 157: 1461-1467. (Pubitemid 18022877)
37. Reisenberger, K., C. Egarter, M. Knöfler, I. Schiebel, H. Gregor, A. M. Hirschl, G. Heinze, and P. Husslein. 1998. Cytokine and prostaglandin production by amnion cells in response to the addition of different bacteria. Am. J. Obstet. Gynecol. 178: 50-53. (Pubitemid 28302793)
38. Rajasingam, D., P. R. Bennett, S. A. Alvi, M. G. Elder, and M. H. Sullivan. 1998. Stimulation of prostaglandin production from intact human fetal membranes by bacteria and bacterial products. Placenta 19: 301-306. (Pubitemid 28224799)
39. Brown, N. L., S. A. Alvi, M. G. Elder, P. R. Bennett, and M. H. Sullivan. 1998. Interleukin-1beta and bacterial endotoxin change the metabolism of prostaglandins E2 and F2alpha in intact term fetal membranes. Placenta 19: 625-630.
40. Breuiller-Fouché, M., M. J. Leroy, O. Dubois, P. Reinaud, A. Chissey, H. Qi, G. Germain, M. A. Fortier, and G. Charpigny. 2010. Differential expression of the enzymatic system controlling synthesis, metabolism, and transport of PGF2 alpha in human fetal membranes. Biol. Reprod. 83: 155-162.
41. Larsen, B., and J. Hwang. 2010. Mycoplasma, Ureaplasma, and adverse pregnancy outcomes: a fresh look. Infect. Dis. Obstet. Gynecol. 2010: 521921.
42. Jones, H. E., K. A. Harris, M. Azizia, L. Bank, B. Carpenter, J. C. Hartley, N. Klein, and D. Peebles. 2009. Differing prevalence and diversity of bacterial species in fetal membranes from very preterm and term labor. PLoS ONE 4: e8205.
43. McGowin, C. L., L. Ma, D. H. Martin, and R. B. Pyles. 2009. Mycoplasma genitalium-encoded MG309 activates NF-kappaB via Toll-like receptors 2 and 6 to elicit proinflammatory cytokine secretion from human genital epithelial cells. Infect. Immun. 77: 1175-1181.
44. Lei, H., E. E. Furth, R. Kalluri, T. Chiou, K. I. Tilly, J. L. Tilly, K. B. Elkon, J. J. Jeffrey, and J. F. Strauss, III. 1996. A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J. Clin. Invest. 98: 1971-1978. (Pubitemid 26376284)
45. Luo, G., V. M. Abrahams, S. Tadesse, E. F. Funai, E. J. Hodgson, J. Gao, and E. R. Norwitz. 2010. Progesterone inhibits basal and TNF-alpha-induced apoptosis in fetal membranes: a novel mechanism to explain progesterone-mediated prevention of preterm birth. Reprod. Sci. 17: 532-539.
46. Moore, R. M., R. J. Silver, and J. J. Moore. 2003. Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. Placenta 24: 173-180. (Pubitemid 37184713)
47. Adams, J. M., and S. Cory. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326. (Pubitemid 28406819)
48. Abrahams, V. M., P. Bole-Aldo, Y. M. Kim, S. L. Straszewski-Chavez, T. Chaiworapongsa, R. Romero, and G. Mor. 2004. Divergent trophoblast responses to bacterial products mediated by TLRs. J. Immunol. 173: 4286-4296. (Pubitemid 39280656)
49. Wang, H., and E. Hirsch. 2003. Bacterially-induced preterm labor and regulation of prostaglandin-metabolizing enzyme expression in mice: the role of toll-like receptor 4. Biol. Reprod. 69: 1957-1963. (Pubitemid 37505342)
50. Elovitz, M. A., and C. Mrinalini. 2004. Animal models of preterm birth. Trends Endocrinol. Metab. 15: 479-487. (Pubitemid 39488151)
51. Lorenz, E., M. Hallman, R. Marttila, R. Haataja, and D. A. Schwartz. 2002. Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population. Pediatr. Res. 52: 373-376. (Pubitemid 34920267)
52. Rey, G., F. Skowronek, J. Alciaturi, J. Alonso, B. Bertoni, and R. Sapiro. 2008. Toll receptor 4 Asp299Gly polymorphism and its association with preterm birth and premature rupture of membranes in a South American population. Mol. Hum. Reprod. 14: 555-559.
53. Agnese, D. M., J. E. Calvano, S. J. Hahm, S. M. Coyle, S. A. Corbett, S. E. Calvano, and S. F. Lowry. 2002. Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J. Infect. Dis. 186: 1522-1525. (Pubitemid 35286126)
54. Hirsch, E., and H. Wang. 2005. The molecular pathophysiology of bacterially induced preterm labor: insights from the murine model. J. Soc. Gynecol. Investig. 12: 145-155. (Pubitemid 40387807)
55. Adams, K. M., J. Lucas, R. P. Kapur, and A. M. Stevens. 2007. LPS induces translocation of TLR4 in amniotic epithelium. Placenta 28: 477-481. (Pubitemid 46593779)
56. Chang, J., S. Jain, D. J. Carl, L. Paolella, R. P. Darveau, M. G. Gravett, and K. M. Adams Waldorf. 2010. Differential host response to LPS variants in amniochorion and the TLR4/MD-2 system in Macaca nemestrina. Placenta 31: 811-817.
57. Ilievski, V., and E. Hirsch. 2010. Synergy between viral and bacterial toll-like receptors leads to amplification of inflammatory responses and preterm labor in the mouse. Biol. Reprod. 83: 767-773.