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Volumn 30, Issue 1, 2013, Pages

Prognostic significance of epigenetic inactivation of p16, p15, MGMT and DAPK genes in follicular lymphoma

Author keywords

DAPK; Follicular lymphoma; Methylation; MGMT; p15; p16

Indexed keywords

DEATH ASSOCIATED PROTEIN KINASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN P15; PROTEIN P16;

EID: 84871603787     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-012-0441-3     Document Type: Article
Times cited : (15)

References (48)
  • 1
    • 0031927984 scopus 로고    scopus 로고
    • New approach to classifying non-Hodgkin's lymphoma: Clinical features of the major histologic subtypes
    • 9704731 1:STN:280:DyaK1czmvVChuw%3D%3D
    • Armitage JO, Weisenburger DD. New approach to classifying non-Hodgkin's lymphoma: clinical features of the major histologic subtypes. J Clin Oncol. 1998;16:2780-95.
    • (1998) J Clin Oncol , vol.16 , pp. 2780-2795
    • Armitage, J.O.1    Weisenburger, D.D.2
  • 2
    • 33644677932 scopus 로고    scopus 로고
    • Ew treatment options have changed the survival of patients with follicular lymphoma
    • 16230674 10.1200/JCO.2005.03.1674 1:CAS:528:DC%2BD2MXhtlWhtrbJ
    • Fisher RI, LeBlanc M, Press OW, Maloney DG, Unger JM, Miller TP. ew treatment options have changed the survival of patients with follicular lymphoma. J Clin Oncol. 2005;23:8447-52.
    • (2005) J Clin Oncol , vol.23 , pp. 8447-8452
    • Fisher, R.I.1    Leblanc, M.2    Press, O.W.3    Maloney, D.G.4    Unger, J.M.5    Miller, T.P.6
  • 4
    • 84855383490 scopus 로고    scopus 로고
    • Follicular lymphoma: Prognostic factors, conventional therapies, and hematopoietic cell transplantation
    • 22226118 10.1016/j.bbmt.2011.11.012
    • Sehn LH, Fenske TS, Laport GG. Follicular lymphoma: prognostic factors, conventional therapies, and hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2012;18:S82-91.
    • (2012) Biol Blood Marrow Transplant , vol.18
    • Sehn, L.H.1    Fenske, T.S.2    Laport, G.G.3
  • 5
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • 3874430 10.1126/science.3874430 1:CAS:528:DyaL2MXktlaqtLk%3D
    • Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science. 1985;228:1440-3.
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 6
    • 33845517974 scopus 로고    scopus 로고
    • Molecular pathways in follicular lymphoma
    • 17039231 10.1038/sj.leu.2404426 1:CAS:528:DC%2BD28XhtlSqurzF
    • Bende RJ, Smit LA, van Noesel CJ. Molecular pathways in follicular lymphoma. Leukemia. 2007;21:18-29.
    • (2007) Leukemia , vol.21 , pp. 18-29
    • Bende, R.J.1    Smit, L.A.2    Van Noesel, C.J.3
  • 7
    • 0142153982 scopus 로고    scopus 로고
    • Profiling aberrant DNA methylation in hematologic neoplasms: A view from the top of the iceberg
    • 14585279 10.1016/S1521-6616(03)00208-0 1:CAS:528:DC%2BD3sXosFSmsLk%3D
    • Esteller M. Profiling aberrant DNA methylation in hematologic neoplasms: a view from the top of the iceberg. Clin Immunol. 2003;109:80-8.
    • (2003) Clin Immunol , vol.109 , pp. 80-88
    • Esteller, M.1
  • 9
    • 0033959282 scopus 로고    scopus 로고
    • The role of DNA hypermethylation in human neoplasia
    • 10675010 10.1002/(SICI)1522-2683(20000101)21:2<329: AID-ELPS329>3.0.CO;2-9 1:CAS:528:DC%2BD3cXht1Ggu7s%3D
    • Toyota M, Issa JP. The role of DNA hypermethylation in human neoplasia. Electrophoresis. 2000;21:329-33.
    • (2000) Electrophoresis , vol.21 , pp. 329-333
    • Toyota, M.1    Issa, J.P.2
  • 10
    • 0031804887 scopus 로고    scopus 로고
    • Hypermethylation of p15/ink4b/MTS2 gene is differentially implicated among non-Hodgkin's lymphoma
    • 9639423 10.1038/sj.leu.2401009 1:CAS:528:DyaK1cXkt1Kiu7g%3D
    • Martinez-Delgado B, Robledo M, Arranz E, Osorio A, Garcia MJ, Echezarreta G, Rivas C, Benitez J. Hypermethylation of p15/ink4b/MTS2 gene is differentially implicated among non-Hodgkin's lymphoma. Leukemia. 1998;12:937-41.
    • (1998) Leukemia , vol.12 , pp. 937-941
    • Martinez-Delgado, B.1    Robledo, M.2    Arranz, E.3    Osorio, A.4    Garcia, M.J.5    Echezarreta, G.6    Rivas, C.7    Benitez, J.8
  • 12
    • 0033199104 scopus 로고    scopus 로고
    • Frequent methylation silencing of p15 INK4b (MTS2) and p16 INK4a (MTS1) in B-cell and T-cell lymphomas
    • 10477703 1:CAS:528:DyaK1MXmtVahs7Y%3D
    • Baur AS, Shaw P, Burri N, Delacrétaz F, Bosman FT, Chaubert P. Frequent methylation silencing of p15 INK4b (MTS2) and p16 INK4a (MTS1) in B-cell and T-cell lymphomas. Blood. 1999;94:1773-81.
    • (1999) Blood , vol.94 , pp. 1773-1781
    • Baur, A.S.1    Shaw, P.2    Burri, N.3    Delacrétaz, F.4    Bosman, F.T.5    Chaubert, P.6
  • 13
    • 36549037146 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of Rb1 in addition to p15 and p16 in mantle cell and follicular lymphoma
    • 17900658 10.1016/j.humpath.2007.05.009 1:CAS:528:DC%2BD2sXhtlOls73J
    • Chim CS, Wong KY, Loong F, Lam WW, Srivastava G. Frequent epigenetic inactivation of Rb1 in addition to p15 and p16 in mantle cell and follicular lymphoma. Hum Pathol. 2007;38:1849-57.
    • (2007) Hum Pathol , vol.38 , pp. 1849-1857
    • Chim, C.S.1    Wong, K.Y.2    Loong, F.3    Lam, W.W.4    Srivastava, G.5
  • 17
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • 10385618 10.1101/gad.13.12.1501 1:CAS:528:DyaK1MXktlOhsLs%3D
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999;13:1501-12.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 18
    • 0034028030 scopus 로고    scopus 로고
    • Repair of O(6)-alkylguanine by alkyltransferases
    • 10767620 10.1016/S1383-5742(00)00017-X 1:CAS:528:DC%2BD3cXisVKgsbs%3D
    • Pegg AE. Repair of O(6)-alkylguanine by alkyltransferases. Mutat Res. 2000;462:83-100.
    • (2000) Mutat Res , vol.462 , pp. 83-100
    • Pegg, A.E.1
  • 19
    • 0035133960 scopus 로고    scopus 로고
    • DAP-kinase: From functional gene cloning to establishment of its role in apoptosis and cancer
    • 11313698 10.1038/sj.cdd.4400794 1:CAS:528:DC%2BD3MXhs1yks7c%3D
    • Cohen O, Kimchi A. DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancer. Cell Death Differ. 2001;8:6-15.
    • (2001) Cell Death Differ , vol.8 , pp. 6-15
    • Cohen, O.1    Kimchi, A.2
  • 20
    • 0036016924 scopus 로고    scopus 로고
    • Death associated protein kinase: From regulation of apoptosis to tumor suppressive function and B cell malignancies
    • 11997670 10.1023/A:1015364104672 1:CAS:528:DC%2BD38XmsVaitbw%3D
    • Ng MH. Death associated protein kinase: from regulation of apoptosis to tumor suppressive function and B cell malignancies. Apoptosis. 2002;7:261-70.
    • (2002) Apoptosis , vol.7 , pp. 261-270
    • Ng, M.H.1
  • 21
    • 53449086842 scopus 로고    scopus 로고
    • Molecular characteristics and prognostic significance of Bcl2/IgH gene rearrangement in Serbian follicular lymphoma patients
    • 18665753 1:CAS:528:DC%2BD1cXhtFGhsb3K
    • Radojkovic M, Ristic S, Colovic M, Cemerikic-Martinovic V, Radojkovic D, Krtolica K. Molecular characteristics and prognostic significance of Bcl2/IgH gene rearrangement in Serbian follicular lymphoma patients. Neoplasma. 2008;55:421-7.
    • (2008) Neoplasma , vol.55 , pp. 421-427
    • Radojkovic, M.1    Ristic, S.2    Colovic, M.3    Cemerikic-Martinovic, V.4    Radojkovic, D.5    Krtolica, K.6
  • 23
    • 34247129670 scopus 로고    scopus 로고
    • Comethylation of p16 and MGMT genes in colorectal carcinoma: Correlation with clinicopathological features and prognostic value
    • 17451198 1:CAS:528:DC%2BD2sXltlWhtL4%3D
    • Krtolica K, Krajnović M, Ušaj-Knežević S, Babić D, Jovanović D, Dimitrijević B. Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic value. World J Gastroenterol. 2007;13:1187-94.
    • (2007) World J Gastroenterol , vol.13 , pp. 1187-1194
    • Krtolica, K.1    Krajnović, M.2    Ušaj-Knežević, S.3    Babić, D.4    Jovanović, D.5    Dimitrijević, B.6
  • 25
    • 0029843950 scopus 로고    scopus 로고
    • Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
    • 8790415 10.1073/pnas.93.18.9821 1:CAS:528:DyaK28XlsFeht7Y%3D
    • Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA. 1996;93:9821-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9821-9826
    • Herman, J.G.1    Graff, J.R.2    Myohanen, S.3    Nelkin, B.D.4    Baylin, S.B.5
  • 26
    • 0033557903 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • 10029064 1:CAS:528:DyaK1MXht1Sjurk%3D
    • Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 1999;59:793-7.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 27
    • 0033564351 scopus 로고    scopus 로고
    • Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies
    • 10361133 1:CAS:528:DyaK1MXjvVGrtLc%3D
    • Katzenellenbogen RA, Baylin SB, Herman JG. Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. Blood. 1999;93:4347-53.
    • (1999) Blood , vol.93 , pp. 4347-4353
    • Katzenellenbogen, R.A.1    Baylin, S.B.2    Herman, J.G.3
  • 28
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • 7553621 1:CAS:528:DyaK2MXoslWmsrk%3D
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 1995;55:4525-30.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 29
    • 0036733566 scopus 로고    scopus 로고
    • Different incidence and pattern of p15INK4b and p16INK4a promoter region hypermethylation in Hodgkin's lymphoma and CD30-positive non-Hodgkin lymphomas
    • 12213729 10.1016/S0002-9440(10)64261-7 1:CAS:528:DC%2BD38XnsFOisrc%3D
    • Garcia MJ, Martinez-Delgado B, Cebrian A, Martinez A, Benitez J, Rivas C. Different incidence and pattern of p15INK4b and p16INK4a promoter region hypermethylation in Hodgkin's lymphoma and CD30-positive non-Hodgkin lymphomas. Am J Pathol. 2002;161:1007-13.
    • (2002) Am J Pathol , vol.161 , pp. 1007-1013
    • Garcia, M.J.1    Martinez-Delgado, B.2    Cebrian, A.3    Martinez, A.4    Benitez, J.5    Rivas, C.6
  • 30
    • 16544395214 scopus 로고    scopus 로고
    • Value of p16INK4a and RASSF1A promoter hypermethylation in prognosis of patients with resectable non-small cell lung cancer
    • 15447998 10.1158/1078-0432.CCR-04-0652 1:CAS:528:DC%2BD2cXnvVOjs74%3D
    • Wang J, Lee JJ, Wang L, Liu DD, Lu C, Fan YH, Kong WK, Mao L. Value of p16INK4a and RASSF1A promoter hypermethylation in prognosis of patients with resectable non-small cell lung cancer. Clin Cancer Res. 2004;10:6119-25.
    • (2004) Clin Cancer Res , vol.10 , pp. 6119-6125
    • Wang, J.1    Lee, J.J.2    Wang, L.3    Liu, D.D.4    Lu, C.5    Fan, Y.H.6    Kong, W.K.7    Mao, L.8
  • 32
    • 53049090443 scopus 로고    scopus 로고
    • Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas
    • 18539616 10.1093/annonc/mdn374 1:STN:280:DC%2BD1cnhslOjtQ%3D%3D
    • Amara K, Trimeche M, Ziadi S, Laatiri A, Hachana M, Korbi S. Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas. Ann Oncol. 2008;19:1774-86.
    • (2008) Ann Oncol , vol.19 , pp. 1774-1786
    • Amara, K.1    Trimeche, M.2    Ziadi, S.3    Laatiri, A.4    Hachana, M.5    Korbi, S.6
  • 33
    • 33646497449 scopus 로고    scopus 로고
    • Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer
    • 16675157 10.1016/j.prp.2005.11.011 1:CAS:528:DC%2BD28XntlWhtb0%3D
    • Lee M, Han WS, Kim OK, Sung SH, Cho MS, Lee SN, Koo H. Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer. Pathol Res Pract. 2006;202:415-24.
    • (2006) Pathol Res Pract , vol.202 , pp. 415-424
    • Lee, M.1    Han, W.S.2    Kim, O.K.3    Sung, S.H.4    Cho, M.S.5    Lee, S.N.6    Koo, H.7
  • 34
    • 0035407045 scopus 로고    scopus 로고
    • Overall survival in aggressive B-cell lymphomas is dependent on the accumulation of alterations in p53, p16, and p27
    • 10.1016/S0002-9440(10)61686-0
    • Sancez-Beato M, Saez AI, Navas IC. Overall survival in aggressive B-cell lymphomas is dependent on the accumulation of alterations in p53, p16, and p27. Am J Pathol. 2001;159:205-13.
    • (2001) Am J Pathol , vol.159 , pp. 205-213
    • Sancez-Beato, M.1    Saez, A.I.2    Navas, I.C.3
  • 35
    • 0031025368 scopus 로고    scopus 로고
    • Distinct patterns of inactivation of p15INK4B and p16INKA characterize the major types oh hematological malignancies
    • 9041182 1:CAS:528:DyaK2sXhs1Kisrc%3D
    • Herman JG, Civin CI, Issa JP, Collector MI, Sharkis SJ, Baylin SB. Distinct patterns of inactivation of p15INK4B and p16INKA characterize the major types oh hematological malignancies. Cancer Res. 1997;57:837-41.
    • (1997) Cancer Res , vol.57 , pp. 837-841
    • Herman, J.G.1    Civin, C.I.2    Issa, J.P.3    Collector, M.I.4    Sharkis, S.J.5    Baylin, S.B.6
  • 36
    • 77955148901 scopus 로고    scopus 로고
    • Frequency of aberrant promoter methylation of p15INK4B and O6-methylguanine-DNA methyltransferase genes in B-cell non-Hodgkin lymphoma: A pilot study
    • 10.2298/ABS1002211K
    • Kraguljac N, Krajnović M, Dimitrijević B, Mihaljević B, Gotić M, Krtolica K. Frequency of aberrant promoter methylation of p15INK4B and O6-methylguanine-DNA methyltransferase genes in B-cell non-Hodgkin lymphoma: a pilot study. Arch Biol Sci. 2010;62:211-21.
    • (2010) Arch Biol Sci , vol.62 , pp. 211-221
    • Kraguljac, N.1    Krajnović, M.2    Dimitrijević, B.3    Mihaljević, B.4    Gotić, M.5    Krtolica, K.6
  • 37
    • 84880318466 scopus 로고    scopus 로고
    • Concomitant aberrant methylation of p15 and MGMT genes in acute myeloid leukemia: Association with a particular immunophenotype of blast cells
    • 10.1007/s12032-012-0289-6
    • Kraguljac KN, Krajnović M, Bogdanović A, Suvajdžić N, Jovanović J, Dimitrijević B, Čolović M, Krtolica K. Concomitant aberrant methylation of p15 and MGMT genes in acute myeloid leukemia: association with a particular immunophenotype of blast cells. Med Oncol. 2012;29:3547-56.
    • (2012) Med Oncol , vol.29 , pp. 3547-3556
    • Kraguljac, K.N.1    Krajnović, M.2    Bogdanović, A.3    Suvajdžić, N.4    Jovanović, J.5    Dimitrijević, B.6    Čolović, M.7    Krtolica, K.8
  • 40
    • 77952093077 scopus 로고    scopus 로고
    • P15INK4b methylation correlates with thrombocytopenia, blast percentage, and survival in myelodysplastic syndrome in a dose dependent manner: Quantitation using pyrosequencing study
    • 19782398 10.1016/j.leukres.2009.09.007 1:CAS:528:DC%2BC3cXlt1agu7k%3D
    • Kim M, Oh B, Kim SY, Park HK, Hwang SM, Kim TY, She CJ, Yang I, Yoon SS, Yoon JH, Lee DS. p15INK4b methylation correlates with thrombocytopenia, blast percentage, and survival in myelodysplastic syndrome in a dose dependent manner: quantitation using pyrosequencing study. Leuk Res. 2010;34:718-22.
    • (2010) Leuk Res , vol.34 , pp. 718-722
    • Kim, M.1    Oh, B.2    Kim, S.Y.3    Park, H.K.4    Hwang, S.M.5    Kim, T.Y.6    She, C.J.7    Yang, I.8    Yoon, S.S.9    Yoon, J.H.10    Lee, D.S.11
  • 41
    • 0031839956 scopus 로고    scopus 로고
    • Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma
    • 9616165 1:CAS:528:DyaK1cXjvVGhtLw%3D
    • Elenitoba-Johnson KSJ, Gascoyne RD, Lim MS, Chhanabai M, Jaffe ES, Raffeld M. Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma. Blood. 1998;91:4677-85.
    • (1998) Blood , vol.91 , pp. 4677-4685
    • Elenitoba-Johnson, K.S.J.1    Gascoyne, R.D.2    Lim, M.S.3    Chhanabai, M.4    Jaffe, E.S.5    Raffeld, M.6
  • 42
    • 0942279488 scopus 로고    scopus 로고
    • Generating mutations but providing chemosensitivity: The role of O6-methylguanine DNA methyltransferase in human cancer
    • 14712205 10.1038/sj.onc.1207316 1:CAS:528:DC%2BD2cXovVKnsQ%3D%3D
    • Esteller M, Herman JG. Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene. 2004;23:1-8.
    • (2004) Oncogene , vol.23 , pp. 1-8
    • Esteller, M.1    Herman, J.G.2
  • 45
    • 5044235077 scopus 로고    scopus 로고
    • Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients
    • 15471559 10.1111/j.1349-7006.2004.tb03254.x 1:CAS:528: DC%2BD2cXpvFOgurc%3D
    • Tozawa T, Tamura G, Honda T, Nawata S, Kimura W, Makino N, Kawata S, Sugai T, Suto T, Motoyama T. Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients. Cancer Sci. 2004;95:736-40.
    • (2004) Cancer Sci , vol.95 , pp. 736-740
    • Tozawa, T.1    Tamura, G.2    Honda, T.3    Nawata, S.4    Kimura, W.5    Makino, N.6    Kawata, S.7    Sugai, T.8    Suto, T.9    Motoyama, T.10
  • 46
    • 0027362582 scopus 로고
    • P53 mutations is associated with progression in follicular lymphomas
    • 8400252 1:CAS:528:DyaK2cXltFeguw%3D%3D
    • Sander CA, Yano T, Clark HM, Harris C, Longo DL, Jafe ES, Raffeld M. p53 mutations is associated with progression in follicular lymphomas. Blood. 1993;82:1994-2004.
    • (1993) Blood , vol.82 , pp. 1994-2004
    • Sander, C.A.1    Yano, T.2    Clark, H.M.3    Harris, C.4    Longo, D.L.5    Jafe, E.S.6    Raffeld, M.7


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