DAP-kinase: From functional gene cloning to establishment of its role in apoptosis and cancer

Cell Death and Differentiation

Volumn 8, Issue 1, 2001, Pages 6-15

  Cohen, O ^a   Kimchi, A ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Apoptosis; Cancer; DAP kinase; Functional gene cloning; Metastasis; Microfilaments

Indexed keywords

ACTIN; AMINO ACID; ANKYRIN; CALCIUM ION; CALMODULIN; DEATH ASSOCIATED PROTEIN KINASE; DNA; FAS LIGAND; GAMMA INTERFERON; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ACTIN FILAMENT; ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; B LYMPHOCYTE; CANCER CELL CULTURE; CANCER GROWTH; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CARCINOMA; CATALYSIS; CELL DEATH; CELL KILLING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME LOCALIZATION; ENZYME REGULATION; EXTRACELLULAR MATRIX; EXTRACTION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG CARCINOMA; METASTASIS; METHYLATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FAMILY; REVIEW; SAMPLE; SEQUENCE HOMOLOGY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CATALYSIS; CLONING, MOLECULAR; GENE EXPRESSION; GENE TARGETING; GENES, TUMOR SUPPRESSOR; HUMANS; MULTIGENE FAMILY; NEOPLASMS; ORGAN SPECIFICITY; PROTEIN STRUCTURE, TERTIARY;

ANIMALIA;

EID: 0035133960     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400794     Document Type: Review

References (39)

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28. Oncogenic mechanisms mediated by DNA methylation
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38. DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis
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