메뉴 건너뛰기




Volumn 22, Issue 2, 2013, Pages 284-299

The Birt-Hogg-Dubé tumor suppressor folliculin negatively regulates ribosomal RNA synthesis

Author keywords

[No Author keywords available]

Indexed keywords

ESTRONE; RAS PROTEIN; RIBOSOME DNA; RIBOSOME RNA;

EID: 84871580429     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds428     Document Type: Article
Times cited : (17)

References (58)
  • 1
    • 0017760671 scopus 로고
    • Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons
    • Birt, A.R., Hogg, G.R. and Dube, W.J. (1977) Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons. Arch. Dermatol., 113, 1674-1677.
    • (1977) Arch. Dermatol. , vol.113 , pp. 1674-1677
    • Birt, A.R.1    Hogg, G.R.2    Dube, W.J.3
  • 3
    • 0035939821 scopus 로고    scopus 로고
    • Birt-Hogg-Dube syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11
    • Khoo, S.K., Bradley, M., Wong, F.K., Hedblad, M.A., Nordenskjold, M. and Teh, B.T. (2001) Birt-Hogg-Dube syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2. Oncogene, 20, 5239-5242.
    • (2001) 2. Oncogene , vol.20 , pp. 5239-5242
    • Khoo, S.K.1    Bradley, M.2    Wong, F.K.3    Hedblad, M.A.4    Nordenskjold, M.5    Teh, B.T.6
  • 5
    • 0000939691 scopus 로고    scopus 로고
    • Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome
    • Nickerson, M.L., Warren, M.B., Toro, J.R., Matrosova, V., Glenn, G., Turner, M.L., Duray, P., Merino, M., Choyke, P., Pavlovich, C.P. et al. (2002) Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome. Cancer Cell, 2, 157-164.
    • (2002) Cancer Cell , vol.2 , pp. 157-164
    • Nickerson, M.L.1    Warren, M.B.2    Toro, J.R.3    Matrosova, V.4    Glenn, G.5    Turner, M.L.6    Duray, P.7    Merino, M.8    Choyke, P.9    Pavlovich, C.P.10
  • 11
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki, K., Zhu, T. and Guan, K.L. (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell, 115, 577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 13
    • 32444433450 scopus 로고    scopus 로고
    • Hypoxia-induced energy stress regulates mRNA translation and cell growth
    • Liu, L., Cash, T.P., Jones, R.G., Keith, B., Thompson, C.B. and Simon, M.C. (2006) Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol. Cell, 21, 521-531.
    • (2006) Mol. Cell , vol.21 , pp. 521-531
    • Liu, L.1    Cash, T.P.2    Jones, R.G.3    Keith, B.4    Thompson, C.B.5    Simon, M.C.6
  • 14
    • 3042818799 scopus 로고    scopus 로고
    • Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome
    • Corradetti, M.N., Inoki, K., Bardeesy, N., DePinho, R.A. and Guan, K.L. (2004) Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome. Genes Dev., 18, 1533-1538.
    • (2004) Genes Dev. , vol.18 , pp. 1533-1538
    • Corradetti, M.N.1    Inoki, K.2    Bardeesy, N.3    Depinho, R.A.4    Guan, K.L.5
  • 16
    • 38449122032 scopus 로고    scopus 로고
    • Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
    • Baba, M., Furihata, M., Hong, S.B., Tessarollo, L., Haines, D.C., Southon, E., Patel, V., Igarashi, P., Alvord, W.G., Leighty, R. et al. (2008) Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J. Natl. Cancer Inst., 100, 140-154.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 140-154
    • Baba, M.1    Furihata, M.2    Hong, S.B.3    Tessarollo, L.4    Haines, D.C.5    Southon, E.6    Patel, V.7    Igarashi, P.8    Alvord, W.G.9    Leighty, R.10
  • 18
    • 34548359242 scopus 로고    scopus 로고
    • The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe
    • van Slegtenhorst, M., Khabibullin, D., Hartman, T.R., Nicolas, E., Kruger, W.D. and Henske, E.P. (2007) The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe. J. Biol. Chem., 282, 24583-24590.
    • (2007) J. Biol. Chem. , vol.282 , pp. 24583-24590
    • van Slegtenhorst, M.1    Khabibullin, D.2    Hartman, T.R.3    Nicolas, E.4    Kruger, W.D.5    Henske, E.P.6
  • 19
    • 33749165120 scopus 로고    scopus 로고
    • The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance
    • Singh, S.R., Zhen, W., Zheng, Z., Wang, H., Oh, S.W., Liu, W., Zbar, B., Schmidt, L.S. and Hou, S.X. (2006) The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance. Oncogene, 25, 5933-5941.
    • (2006) Oncogene , vol.25 , pp. 5933-5941
    • Singh, S.R.1    Zhen, W.2    Zheng, Z.3    Wang, H.4    Oh, S.W.5    Liu, W.6    Zbar, B.7    Schmidt, L.S.8    Hou, S.X.9
  • 20
    • 66449135377 scopus 로고    scopus 로고
    • Thinking outside the box about Ras
    • Kyriakis, J.M. (2009) Thinking outside the box about Ras. J. Biol. Chem., 284, 10993-10994.
    • (2009) J. Biol. Chem. , vol.284 , pp. 10993-10994
    • Kyriakis, J.M.1
  • 24
    • 0030724368 scopus 로고    scopus 로고
    • The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells
    • Yamamoto, T., Harada, N., Kano, K., Taya, S., Canaani, E., Matsuura, Y., Mizoguchi, A., Ide, C. and Kaibuchi, K. (1997) The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J. Cell Biol., 139, 785-795.
    • (1997) J. Cell Biol. , vol.139 , pp. 785-795
    • Yamamoto, T.1    Harada, N.2    Kano, K.3    Taya, S.4    Canaani, E.5    Matsuura, Y.6    Mizoguchi, A.7    Ide, C.8    Kaibuchi, K.9
  • 26
    • 49449101955 scopus 로고    scopus 로고
    • Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I
    • Bierhoff, H., Dundr, M., Michels, A.A. and Grummt, I. (2008) Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol. Cell Biol., 28, 4988-4998.
    • (2008) Mol. Cell Biol. , vol.28 , pp. 4988-4998
    • Bierhoff, H.1    Dundr, M.2    Michels, A.A.3    Grummt, I.4
  • 27
    • 0037363075 scopus 로고    scopus 로고
    • Does the ribosome translate cancer? Nat
    • Ruggero, D. and Pandolfi, P.P. (2003) Does the ribosome translate cancer? Nat. Rev. Cancer, 3, 179-192.
    • (2003) Rev. Cancer , vol.3 , pp. 179-192
    • Ruggero, D.1    Pandolfi, P.P.2
  • 29
    • 0028911033 scopus 로고
    • Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product
    • Cavanaugh, A.H., Hempel, W.M., Taylor, L.J., Rogalsky, V., Todorov, G. and Rothblum, L.I. (1995) Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product. Nature, 374, 177-180.
    • (1995) Nature , vol.374 , pp. 177-180
    • Cavanaugh, A.H.1    Hempel, W.M.2    Taylor, L.J.3    Rogalsky, V.4    Todorov, G.5    Rothblum, L.I.6
  • 30
    • 0036884829 scopus 로고    scopus 로고
    • The retinoblastoma tumour suppressor in development and cancer
    • Classon, M. and Harlow, E. (2002) The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer, 2, 910-917.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 910-917
    • Classon, M.1    Harlow, E.2
  • 31
    • 56149116334 scopus 로고    scopus 로고
    • Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription
    • Fatyol, K. and Grummt, I. (2008) Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription. Biochim. Biophys. Acta., 1779, 850-859.
    • (2008) Biochim. Biophys. Acta. , vol.1779 , pp. 850-859
    • Fatyol, K.1    Grummt, I.2
  • 33
    • 14644388169 scopus 로고    scopus 로고
    • Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development
    • Li, W.X. (2005) Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development. Dev. Dyn., 232, 656-672.
    • (2005) Dev. Dyn. , vol.232 , pp. 656-672
    • Li, W.X.1
  • 35
    • 0031964429 scopus 로고    scopus 로고
    • Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues
    • Karim, F.D. and Rubin, G.M. (1998) Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development, 125, 1-9.
    • (1998) Development , vol.125 , pp. 1-9
    • Karim, F.D.1    Rubin, G.M.2
  • 36
    • 65849386298 scopus 로고    scopus 로고
    • Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2
    • Benedict, J.W., Getty, A.L., Wishart, T.M., Gillingwater, T.H. and Pearce, D.A. (2009) Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2. J. Neurosci. Res., 87, 2157-2166.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 2157-2166
    • Benedict, J.W.1    Getty, A.L.2    Wishart, T.M.3    Gillingwater, T.H.4    Pearce, D.A.5
  • 37
    • 17044376248 scopus 로고    scopus 로고
    • Elevation of Hook1 in a disease model of Batten disease does not affect a novel interaction between Ankyrin G and Hook1
    • Weimer, J.M., Chattopadhyay, S., Custer, A.W. and Pearce, D.A. (2005) Elevation of Hook1 in a disease model of Batten disease does not affect a novel interaction between Ankyrin G and Hook1. Biochem. Biophys. Res. Commun., 330, 1176-1181.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 1176-1181
    • Weimer, J.M.1    Chattopadhyay, S.2    Custer, A.W.3    Pearce, D.A.4
  • 38
    • 0030923133 scopus 로고    scopus 로고
    • Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions
    • Aronheim, A., Zandi, E., Hennemann, H., Elledge, S.J. and Karin, M. (1997) Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions. Mol. Cell Biol., 17, 3094-3102.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 3094-3102
    • Aronheim, A.1    Zandi, E.2    Hennemann, H.3    Elledge, S.J.4    Karin, M.5
  • 39
    • 0033618256 scopus 로고    scopus 로고
    • Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast
    • Russell, S.J., Steger, K.A. and Johnston, S.A. (1999) Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast. J. Biol. Chem., 274, 21943-21952.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21943-21952
    • Russell, S.J.1    Steger, K.A.2    Johnston, S.A.3
  • 40
    • 0037650101 scopus 로고    scopus 로고
    • Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levels
    • Arabi, A., Rustum, C., Hallberg, E. and Wright, A.P. (2003) Accumulation of c-Myc and proteasomes at the nucleoli of cells containing elevated c-Myc protein levels. J. Cell Sci., 116, 1707-1717.
    • (2003) J. Cell Sci. , vol.116 , pp. 1707-1717
    • Arabi, A.1    Rustum, C.2    Hallberg, E.3    Wright, A.P.4
  • 41
    • 0035970007 scopus 로고    scopus 로고
    • Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation
    • Mattsson, K., Pokrovskaja, K., Kiss, C., Klein, G. and Szekely, L. (2001) Proteins associated with the promyelocytic leukemia gene product (PML)-containing nuclear body move to the nucleolus upon inhibition of proteasome-dependent protein degradation. Proc. Natl. Acad. Sci. USA, 98, 1012-1017.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1012-1017
    • Mattsson, K.1    Pokrovskaja, K.2    Kiss, C.3    Klein, G.4    Szekely, L.5
  • 44
    • 11244281646 scopus 로고    scopus 로고
    • RNA polymerases I and III, growth control and cancer
    • White, R.J. (2005) RNA polymerases I and III, growth control and cancer. Nat. Rev. Mol. Cell Biol., 6, 69-78.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 69-78
    • White, R.J.1
  • 45
    • 14744297005 scopus 로고    scopus 로고
    • Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
    • Grewal, S.S., Li, L., Orian, A., Eisenman, R.N. and Edgar, B.A. (2005) Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat. Cell Biol., 7, 295-302.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 295-302
    • Grewal, S.S.1    Li, L.2    Orian, A.3    Eisenman, R.N.4    Edgar, B.A.5
  • 46
    • 0025874324 scopus 로고
    • Identification of the genes coding for the second-largest subunits of RNA polymerases I and III of Drosophila melanogaster
    • Seifarth, W., Petersen, G., Kontermann, R., Riva, M., Huet, J. and Bautz, E.K. (1991) Identification of the genes coding for the second-largest subunits of RNA polymerases I and III of Drosophila melanogaster. Mol. Gen. Genet., 228, 424-432.
    • (1991) Mol. Gen. Genet. , vol.228 , pp. 424-432
    • Seifarth, W.1    Petersen, G.2    Kontermann, R.3    Riva, M.4    Huet, J.5    Bautz, E.K.6
  • 48
    • 77953719290 scopus 로고    scopus 로고
    • Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling
    • Hong, S.B., Oh, H., Valera, V.A., Stull, J., Ngo, D.T., Baba, M., Merino, M.J., Linehan, W.M. and Schmidt, L.S. Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling. Mol. Cancer, 9, 160.
    • Mol. Cancer , vol.9 , pp. 160
    • Hong, S.B.1    Oh, H.2    Valera, V.A.3    Stull, J.4    Ngo, D.T.5    Baba, M.6    Merino, M.J.7    Linehan, W.M.8    Schmidt, L.S.9
  • 49
    • 1542343973 scopus 로고    scopus 로고
    • mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability
    • Mayer, C., Zhao, J., Yuan, X. and Grummt, I. (2004) mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev., 18, 423-434.
    • (2004) Genes Dev. , vol.18 , pp. 423-434
    • Mayer, C.1    Zhao, J.2    Yuan, X.3    Grummt, I.4
  • 50
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • Rubin, G.M. and Spradling, A.C. (1982) Genetic transformation of Drosophila with transposable element vectors. Science, 218, 348-353.
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 51
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A.H. and Perrimon, N. (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development, 118, 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 52
    • 0036185054 scopus 로고    scopus 로고
    • RNAi triggered by symmetrically transcribed transgenes in Drosophila melanogaster
    • Giordano, E., Rendina, R., Peluso, I. and Furia, M. (2002) RNAi triggered by symmetrically transcribed transgenes in Drosophila melanogaster. Genetics, 160, 637-648.
    • (2002) Genetics , vol.160 , pp. 637-648
    • Giordano, E.1    Rendina, R.2    Peluso, I.3    Furia, M.4
  • 53
    • 0037516886 scopus 로고    scopus 로고
    • Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling
    • Li, J. and Li, W.X. (2003) Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling. Genetics, 164, 247-258.
    • (2003) Genetics , vol.164 , pp. 247-258
    • Li, J.1    Li, W.X.2
  • 54
    • 33748308794 scopus 로고    scopus 로고
    • JAK signaling globally counteracts heterochromatic gene silencing
    • Shi, S., Calhoun, H.C., Xia, F., Li, J., Le, L. and Li, W.X. (2006) JAK signaling globally counteracts heterochromatic gene silencing. Nat. Genet., 38, 1071-1076.
    • (2006) Nat. Genet. , vol.38 , pp. 1071-1076
    • Shi, S.1    Calhoun, H.C.2    Xia, F.3    Li, J.4    Le, L.5    Li, W.X.6
  • 55
    • 0000479657 scopus 로고
    • Transient expression of genes introduced into cultured cells of Drosophila
    • Di Nocera, P.P. and Dawid, I.B. (1983) Transient expression of genes introduced into cultured cells of Drosophila. Proc. Natl. Acad. Sci. USA, 80, 7095-7098.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 7095-7098
    • Nocera, P.P.D.1    Dawid, I.B.2
  • 56
    • 33751543026 scopus 로고    scopus 로고
    • A novel function of Drosophila eIF4A as a negative regulator of Dpp/BMP signalling that mediates SMAD degradation
    • Li, J. and Li, W.X. (2006) A novel function of Drosophila eIF4A as a negative regulator of Dpp/BMP signalling that mediates SMAD degradation. Nat. Cell Biol., 8, 1407-1414.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1407-1414
    • Li, J.1    Li, W.X.2
  • 57
    • 43149084600 scopus 로고    scopus 로고
    • Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability
    • Shi, S., Larson, K., Guo, D., Lim, S.J., Dutta, P., Yan, S.J. and Li, W.X. (2008) Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability. Nat. Cell Biol., 10, 489-496.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 489-496
    • Shi, S.1    Larson, K.2    Guo, D.3    Lim, S.J.4    Dutta, P.5    Yan, S.J.6    Li, W.X.7
  • 58
    • 55349106559 scopus 로고    scopus 로고
    • Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA
    • Connolly, K., Rife, J.P. and Culver, G. (2008) Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA. Mol. Microbiol., 70, 1062-1075.
    • (2008) Mol. Microbiol. , vol.70 , pp. 1062-1075
    • Connolly, K.1    Rife, J.P.2    Culver, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.