The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway

Cancer Genetics and Cytogenetics

Volumn 180, Issue 2, 2008, Pages 100-109

  Yang, Youfeng ^a   Padilla Nash, Hesed M ^a   Vira, Manish A ^a   Abu Asab, Mones S ^a   Val, Daniel ^a   Worrell, Robert ^a   Tsokos, Maria ^a   Merino, Maria J ^b   Pavlovich, Christian P ^a   Ried, Thomas ^a   Linehan, W Marston ^a   Vocke, Cathy D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERLEUKIN 2;

ADULT; ARTICLE; BIRT HOGG DUBE SYNDROME; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER MODEL; CARCINOGENICITY; CASE REPORT; CELL ISOLATION; CELL STRAIN UOK 257; CELL ULTRASTRUCTURE; CHROMOSOME 17P; CHROMOSOME LOSS; CLEAR CELL CARCINOMA; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONTACT INHIBITION; DRUG MEGADOSE; EPITHELIUM CELL; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; MALE; METASTASIS; ONCOGENE MYC; PRIORITY JOURNAL; RECURRENT CANCER; SCID MOUSE; SPECTRAL KARYOTYPING; SYMPTOM; TRIPLOIDY; TUMOR XENOGRAFT;

CARCINOMA, RENAL CELL; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 17; GENE DUPLICATION; GENES, MYC; HUMANS; KARYOTYPING; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PLOIDIES; PROTO-ONCOGENE PROTEINS; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; SYNDROME; TUMOR SUPPRESSOR PROTEINS;

EID: 38149094921     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.10.010     Document Type: Article

References (16)

1. Khoo S.K., Bradley M., Wong F.K., Hedblad M.A., Nordenskjöld M., and Teh B.T. Birt-Hogg-Dubé syndrome: mapping of a novel hereditary neoplasia gene to chromosome 17p12-q11.2. Oncogene 20 (2001) 5239-5242
2. Schmidt L.S., Warren M.B., Nickerson M.L., Weirich G., Matrosova V., Toro J.R., Turner M.L., Duray P., Merino M., Hewitt S., Pavlovich C.P., Glenn G., Greenberg C.R., Linehan W.M., and Zbar B. Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2. Am J Hum Genet 69 (2001) 876-882
3. Nickerson M.L., Warren M.B., Toro J.R., Matrosova V., Glenn G., Turner M.L., Duray P., Merino M., Choyke P., Pavlovich C.P., Sharma N., Walther M., Munroe D., Hill R., Maher E., Greenberg C., Lerman M.I., Linehan W.M., Zbar B., and Schmidt L.S. Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome. Cancer Cell 2 (2002) 157-164
4. Pavlovich C.P., Walther M.M., Eyler R.A., Hewitt S.M., Zbar B., Linehan W.M., and Merino M.J. Renal tumors in the Birt-Hogg-Dubé syndrome. Am J Surg Pathol 26 (2002) 1542-1552
5. Tickoo S.K., Reuter V.E., Amin M.B., Srigley J.R., Epstein J.I., and Min K.W. Renal oncocytosis: a morphologic study of fourteen cases. Am J Surg Pathol 23 (1999) 1094-1101
6. Adley B.P., Smith N.D., Nayar R., and Yang X.J. Birt-Hogg-Dubé syndrome: clinicopathologic findings and genetic alterations. Arch Pathol Lab Med 130 (2006) 1865-1870
7. Vocke C.D., Yang Y., Pavlovich C.P., Schmidt L.S., Nickerson M.L., Torres-Cabala C.A., Merino M.J., Walther M.M., Zbar B., and Linehan W.M. High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors. [Erratum in: J Natl Cancer Inst. 2005;97:1096]. J Natl Cancer Inst 97 (2005) 931-935
8. Gad S., Lefèvre S.H., Khoo S.K., Giraud S., Vieillefond A., Vasiliu V., Ferlicot S., Molinié V., Denoux Y., Thiounn N., Chrétien Y., Méjean A., Zerbib M., Benoît G., Hervé J.M., Allègre G., Bressac-de Paillerets B., Teh B.T., and Richard S. Mutations in BHD and TP53 genes, but not in HNF1β gene, in a large series of sporadic chromophobe renal cell carcinoma. [Erratum in: Br J Cancer 2007;96:1314]. Br J Cancer 96 (2007) 336-340
9. Baba M., Hong S.B., Sharma N., Warren M.B., Nickerson M.L., Iwamatsu A., Esposito D., Gillette W.K., Hopkins III R.F., Hartley J.L., Furihata M., Oishi S., Zhen W., Burke Jr. T.R., Linehan W.M., Schmidt L.S., and Zbar B. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling. Proc Natl Acad Sci U S A 103 (2006) 15552-15557
10. Garvin A.J., Re G.G., Tarnowski B.I., Hazen-Martin D.J., and Sens D.A. The G401 cell line, utilized for studies of chromosomal changes in Wilms' tumor, is derived from a rhabdoid tumor of the kidney. Am J Pathol 142 (1993) 375-380
11. Williams R.D., Elliott A.Y., Stein N., and Fraley E.E. In vitro cultivation of human renal cell cancer: I. Establishment of cells in culture. In Vitro 12 (1976) 623-627
12. Schröck E., du Manoir S., Veldman T., Schoell B., Wienberg J., Ferguson-Smith M.A., Ning Y., Ledbetter D.H., Bar-Am I., Soenksen D., Garini Y., and Ried T. Multicolor spectral karyotyping of human chromosomes. Science 273 (1996) 494-497
13. Li G., Cottier M., Sabido O., Gentil-Perret A., Lambert C., Genin C., and Tostain J. Different DNA ploidy patterns for the differentiation of common subtypes of renal tumors. Cell Oncol 27 (2005) 51-56
14. Padilla-Nash H.M., Barenboim-Stapleton L., Difilippantonio M.J., and Ried T. Spectral karyotyping analysis of human and mouse chromosomes. Nat Protoc 1 (2006) 3129-3142. http://www.nature.com/nprot/journal/v1/n6/abs/nprot.2006.358.html ]
15. ISCN 2005: an international system for human cytogenetic nomenclature (2005). In: Shaffer L.G., and Tommerup N. (Eds) (2005), S. Karger, Basel
16. Kuroda N., Toi M., Hiroi M., Shuin T., and Enzan H. Review of renal oncocytoma with focus on clinical and pathobiological aspects. Histol Histopathol 18 (2003) 935-942