Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation

British Journal of Pharmacology

Volumn 168, Issue 2, 2013, Pages 421-431

  Oh, Shin Bi ^a   Park, Hee Ra ^a   Jang, Young Jung ^a   Choi, Seon Young ^a   Son, Tae Gen ^b   Lee, Jaewon ^a  

^a Pusan National University   (South Korea)

^b Dongnam Institute of Radiological and Medical Science   (South Korea)

Author keywords

brain tumour; cell death; neural progenitor cell; neurogenesis; oxidative stress; radiotherapy; whole brain irradiation

Indexed keywords

BAICALEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ANTIOXIDANT; FLAVANONE DERIVATIVE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; GAMMA RADIATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEARNING; MALE; MAZE TEST; MEMORY; MEMORY CONSOLIDATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OXIDATIVE STRESS; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION PROTECTION; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPATIAL MEMORY; STEM CELL; WHOLE BODY RADIATION; ANIMAL; AVOIDANCE BEHAVIOR; C57BL MOUSE; CELL LINE; COGNITION; CYTOLOGY; DRUG EFFECT; MEMORY DISORDER; METABOLISM; NEURAL STEM CELL; PHYSIOLOGY; RADIATION EXPOSURE;

ANIMALS; ANTIOXIDANTS; AVOIDANCE LEARNING; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL LINE; COGNITION; COGNITION DISORDERS; FLAVANONES; GAMMA RAYS; HIPPOCAMPUS; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROGENESIS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS;

MLCS; MLOWN;

EID: 84871579017     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02142.x     Document Type: Article

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