Apigenin attenuates dopamine-induced apoptosis in melanocytes via oxidative stress-related p38, c-Jun NH2-terminal kinase and Akt signaling

Journal of Dermatological Science

Volumn 63, Issue 1, 2011, Pages 10-16

  Lin, Mao ^a   Lu, Shan shan ^a   Wang, Ao xue ^a   Qi, Xiao yi ^a   Zhao, Dan ^a   Wang, Zhao hui ^a   Man, Mao Qiang ^b   Tu, Cai xia ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION   (United States)

Author keywords

Akt; Apigenin; C Jun NH2 terminal kinase; Dopamine; P38; Vitiligo

Indexed keywords

APIGENIN; CASPASE 3; DOPAMINE; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MELANOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; APIGENIN; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MELANOCYTES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; VITILIGO;

EID: 79957568234     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2011.03.007     Document Type: Article

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