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Volumn 73, Issue 6, 2007, Pages 793-804

Protective effect of baicalein against endotoxic shock in rats in vivo and in vitro

Author keywords

Baicalein; Circulatory failure; NF B; Nitric oxide; Reactive oxygen species; Sepsis

Indexed keywords

BAICALEIN; DNA; FLAVONOID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SCUTELLARIA BAICALENSIS EXTRACT; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846858005     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.11.025     Document Type: Article
Times cited : (93)

References (52)
  • 1
    • 0030843156 scopus 로고    scopus 로고
    • Sepsis, a new hypothesis for pathogenesis of the disease process
    • Bone R.C., Grodzin C.J., and Balk R.A. Sepsis, a new hypothesis for pathogenesis of the disease process. Chest 112 (1997) 235-243
    • (1997) Chest , vol.112 , pp. 235-243
    • Bone, R.C.1    Grodzin, C.J.2    Balk, R.A.3
  • 2
    • 0032433470 scopus 로고    scopus 로고
    • Has the mortality of septic shock changed with time?
    • Friedman G., Silva E., and Vincent J.L. Has the mortality of septic shock changed with time?. Crit Care Med 26 (1998) 2078-2086
    • (1998) Crit Care Med , vol.26 , pp. 2078-2086
    • Friedman, G.1    Silva, E.2    Vincent, J.L.3
  • 3
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler A.P., and Bernard G.R. Treating patients with severe sepsis. N Engl J Med 340 (1999) 207-214
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 4
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus D.C., Linde-Zwirbe W.T., Lidicker J., Clermont G., Carcillo J., and Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29 (2001) 1303-1310
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirbe, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 5
    • 0036216323 scopus 로고    scopus 로고
    • Therapeutic selection: has its time come?
    • Marik P.E., and Zalopa G.P. Therapeutic selection: has its time come?. Crit Care Med 30 (2002) 949-952
    • (2002) Crit Care Med , vol.30 , pp. 949-952
    • Marik, P.E.1    Zalopa, G.P.2
  • 7
    • 2442468054 scopus 로고    scopus 로고
    • Stress-hyperglycemia, insulin and immunomodulation in sepsis
    • Marix P.E., and Raghavan M. Stress-hyperglycemia, insulin and immunomodulation in sepsis. Intensive Care Med 30 (2004) 748-756
    • (2004) Intensive Care Med , vol.30 , pp. 748-756
    • Marix, P.E.1    Raghavan, M.2
  • 8
    • 0021243692 scopus 로고
    • Secretory products of macrophages and their physiological functions
    • Takemura R., and Werb Z. Secretory products of macrophages and their physiological functions. Am J Physiol 1246 (1984) C1-C9
    • (1984) Am J Physiol , vol.1246
    • Takemura, R.1    Werb, Z.2
  • 9
    • 0029889088 scopus 로고    scopus 로고
    • Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome
    • Jansen M.J., Hendriks T., Vogels M.T., van der Meer J.W., and Goris R.J. Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome. Crit Care Med 24 (1996) 1196-1202
    • (1996) Crit Care Med , vol.24 , pp. 1196-1202
    • Jansen, M.J.1    Hendriks, T.2    Vogels, M.T.3    van der Meer, J.W.4    Goris, R.J.5
  • 10
    • 0027237013 scopus 로고
    • Role of tumor necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock
    • Thiemermann C., Wu C.C., Szabo C., Pen'etti M., and Vane J.R. Role of tumor necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol 110 (1993) 177-182
    • (1993) Br J Pharmacol , vol.110 , pp. 177-182
    • Thiemermann, C.1    Wu, C.C.2    Szabo, C.3    Pen'etti, M.4    Vane, J.R.5
  • 11
    • 0027333425 scopus 로고
    • Tumor necrosis factor, other cytokines and disease
    • Tracey K.J., and Cerami A. Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol 9 (1993) 317-343
    • (1993) Annu Rev Cell Biol , vol.9 , pp. 317-343
    • Tracey, K.J.1    Cerami, A.2
  • 12
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • de Waal M.R., Abrams J., Bennett B., Figdor C.G., and de Vries J.E. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174 (1991) 1209-1220
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • de Waal, M.R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 14
    • 0027478367 scopus 로고
    • Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
    • Gerard C., Bruyns C., Marchant A., Abramowicz D., Vandenabeele P., Delvanx A., et al. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med 177 (1993) 547-550
    • (1993) J Exp Med , vol.177 , pp. 547-550
    • Gerard, C.1    Bruyns, C.2    Marchant, A.3    Abramowicz, D.4    Vandenabeele, P.5    Delvanx, A.6
  • 15
    • 0036186055 scopus 로고    scopus 로고
    • Nitric oxide-derived nitrate anion contributes to endotoxic shock and multiple organ injury/dysfunction
    • Yang F., Comtois A.S., Fang L., Hartman N.G., and Blaise G. Nitric oxide-derived nitrate anion contributes to endotoxic shock and multiple organ injury/dysfunction. Crit Care Med 30 (2002) 650-657
    • (2002) Crit Care Med , vol.30 , pp. 650-657
    • Yang, F.1    Comtois, A.S.2    Fang, L.3    Hartman, N.G.4    Blaise, G.5
  • 16
    • 0028967728 scopus 로고
    • Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo
    • Szabo C., Salzman A.L., and Ischiropoulos H. Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo. FEBS Lett 363 (1995) 235-238
    • (1995) FEBS Lett , vol.363 , pp. 235-238
    • Szabo, C.1    Salzman, A.L.2    Ischiropoulos, H.3
  • 17
    • 0028957065 scopus 로고
    • Tumor-derived factor synergizes with IFN-gamma and LPS, IL-2 or TNF-alpha to promote macrophage synthesis of TNF-alpha and TNF receptors for autocrine induction of nitric oxide synthase and enhanced nitric oxide-mediated tumor cytotoxicity
    • Jiang H., Stewart C.A., and Leu R.W. Tumor-derived factor synergizes with IFN-gamma and LPS, IL-2 or TNF-alpha to promote macrophage synthesis of TNF-alpha and TNF receptors for autocrine induction of nitric oxide synthase and enhanced nitric oxide-mediated tumor cytotoxicity. Immunobiology 192 (1995) 321-342
    • (1995) Immunobiology , vol.192 , pp. 321-342
    • Jiang, H.1    Stewart, C.A.2    Leu, R.W.3
  • 18
    • 0031695361 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS) stimulates the production of tumor necrosis factor (TNF)-alpha and expression of inducible nitric oxide synthase (iNOS) by osteoclasts (OCL) in murine bone marrow cell culture
    • Kikkawa I., Saito S., Tominaga K., Hoshino Y., Ooi Y., and Nakano M. Lipopolysaccharide (LPS) stimulates the production of tumor necrosis factor (TNF)-alpha and expression of inducible nitric oxide synthase (iNOS) by osteoclasts (OCL) in murine bone marrow cell culture. Microbiol Immunol 142 (1998) 591-598
    • (1998) Microbiol Immunol , vol.142 , pp. 591-598
    • Kikkawa, I.1    Saito, S.2    Tominaga, K.3    Hoshino, Y.4    Ooi, Y.5    Nakano, M.6
  • 19
    • 0024560261 scopus 로고
    • Changes in the levels of endogenous antioxidants in the liver of mice with experimental endotoxemia and the protective effects of the antioxidants
    • Sugino K., Dohi K., Yamada K., and Kawasaki T. Changes in the levels of endogenous antioxidants in the liver of mice with experimental endotoxemia and the protective effects of the antioxidants. Surgery 105 (1989) 200-206
    • (1989) Surgery , vol.105 , pp. 200-206
    • Sugino, K.1    Dohi, K.2    Yamada, K.3    Kawasaki, T.4
  • 20
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide
    • Beckman J.S., Beckman T.W., Chen J., Marshall P.A., and Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87 (1990) 1620-1624
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 21
    • 0026744448 scopus 로고
    • Multiple organ failure. Pathophysiology and potential future therapy
    • Deitch E.A. Multiple organ failure. Pathophysiology and potential future therapy. Ann Surg 216 (1992) 117-134
    • (1992) Ann Surg , vol.216 , pp. 117-134
    • Deitch, E.A.1
  • 22
    • 0029986709 scopus 로고    scopus 로고
    • Comparison of the effects of amino-guanidine and N omega-nitro-l-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat
    • Wu C.C., Ruetten H., and Thiemermann C. Comparison of the effects of amino-guanidine and N omega-nitro-l-arginine methyl ester on the multiple organ dysfunction caused by endotoxaemia in the rat. Eur J Pharmacol 300 (1996) 99-104
    • (1996) Eur J Pharmacol , vol.300 , pp. 99-104
    • Wu, C.C.1    Ruetten, H.2    Thiemermann, C.3
  • 23
    • 0035221973 scopus 로고    scopus 로고
    • Anti-HIV activity of medicinal herbs: usage and potential development
    • Wu J.A., Attele A.S., Zhang L., and Yuan C.S. Anti-HIV activity of medicinal herbs: usage and potential development. Am J Chin Med 29 (2001) 69-81
    • (2001) Am J Chin Med , vol.29 , pp. 69-81
    • Wu, J.A.1    Attele, A.S.2    Zhang, L.3    Yuan, C.S.4
  • 24
    • 0038464586 scopus 로고    scopus 로고
    • Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties
    • Bochorakova H., Paulova H., Slanina J., Musil P., and Taborska E. Main flavonoids in the root of Scutellaria baicalensis cultivated in Europe and their comparative antiradical properties. Phytother Res 17 (2003) 640-644
    • (2003) Phytother Res , vol.17 , pp. 640-644
    • Bochorakova, H.1    Paulova, H.2    Slanina, J.3    Musil, P.4    Taborska, E.5
  • 25
    • 12244301218 scopus 로고    scopus 로고
    • Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes
    • Shen Y.C., Chiou W.F., Chou Y.C., and Chen C.F. Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur J Pharmacol 465 (2003) 171-181
    • (2003) Eur J Pharmacol , vol.465 , pp. 171-181
    • Shen, Y.C.1    Chiou, W.F.2    Chou, Y.C.3    Chen, C.F.4
  • 26
    • 0030931592 scopus 로고    scopus 로고
    • Effects of flavonoids isolated from scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells
    • Kimura Y., Yokoi K., Matsushita N., and Okuda H. Effects of flavonoids isolated from scutellariae radix on the production of tissue-type plasminogen activator and plasminogen activator inhibitor-1 induced by thrombin and thrombin receptor agonist peptide in cultured human umbilical vein endothelial cells. J Pharm Pharmacol 49 (1997) 816-822
    • (1997) J Pharm Pharmacol , vol.49 , pp. 816-822
    • Kimura, Y.1    Yokoi, K.2    Matsushita, N.3    Okuda, H.4
  • 27
    • 0041672474 scopus 로고    scopus 로고
    • Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis
    • Zhang D.Y., Wu J., Ye F., Xue L., Jiang S., Yi J., et al. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Cancer Res 63 (2003) 4037-4043
    • (2003) Cancer Res , vol.63 , pp. 4037-4043
    • Zhang, D.Y.1    Wu, J.2    Ye, F.3    Xue, L.4    Jiang, S.5    Yi, J.6
  • 28
    • 0033022302 scopus 로고    scopus 로고
    • Inhibitory effects of baicalein and wogonin on lipo- polysaccharide-induced nitric oxide production in macrophages
    • Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipo- polysaccharide-induced nitric oxide production in macrophages. Pharmacol Toxicol 84 (1999) 288-291
    • (1999) Pharmacol Toxicol , vol.84 , pp. 288-291
    • Wakabayashi, I.1
  • 29
    • 0035087432 scopus 로고    scopus 로고
    • Melatonin prevents endotoxin-induced circulatory failure in rats
    • Wu C.C., Chiao C.W., Hsiao G., Chen A., and Yen M.H. Melatonin prevents endotoxin-induced circulatory failure in rats. J Pineal Res 30 (2001) 147-156
    • (2001) J Pineal Res , vol.30 , pp. 147-156
    • Wu, C.C.1    Chiao, C.W.2    Hsiao, G.3    Chen, A.4    Yen, M.H.5
  • 30
    • 0141512979 scopus 로고    scopus 로고
    • Inhibition by terbutaline of nitric oxide and superoxide anion levels of endotoxin-induced organs injury in the anesthetized rat
    • Liaw W.J., Tzao C., Wu J.Y., Chen S.J., Wang J.H., and Wu C.C. Inhibition by terbutaline of nitric oxide and superoxide anion levels of endotoxin-induced organs injury in the anesthetized rat. Shock 19 (2003) 281-288
    • (2003) Shock , vol.19 , pp. 281-288
    • Liaw, W.J.1    Tzao, C.2    Wu, J.Y.3    Chen, S.J.4    Wang, J.H.5    Wu, C.C.6
  • 31
    • 0033780038 scopus 로고    scopus 로고
    • Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase
    • Hong H.J., Loh S.H., and Yen M.H. Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase. Br J Pharmacol 131 (2000) 631-637
    • (2000) Br J Pharmacol , vol.131 , pp. 631-637
    • Hong, H.J.1    Loh, S.H.2    Yen, M.H.3
  • 32
    • 33645386321 scopus 로고    scopus 로고
    • N-acetylsecoboldine as a novel agent prevents acute renal failure during endotoxemia
    • Chiao C.W., Lee S.S., Wu C.C., and Su M.J. N-acetylsecoboldine as a novel agent prevents acute renal failure during endotoxemia. Eur J Pharmacol 535 (2006) 291-300
    • (2006) Eur J Pharmacol , vol.535 , pp. 291-300
    • Chiao, C.W.1    Lee, S.S.2    Wu, C.C.3    Su, M.J.4
  • 33
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65 (1983) 55-63
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 34
    • 1542358820 scopus 로고    scopus 로고
    • Measurements of nitric oxide concentration and hyporeactivity in rat superior mesenteric artery exposed to endotoxin
    • Hernanz R., Alonso M.J., Zibrandtsen H., Alvarez Y., Salaices M., and Simonsen U. Measurements of nitric oxide concentration and hyporeactivity in rat superior mesenteric artery exposed to endotoxin. Cardiovasc Res 62 (2004) 202-211
    • (2004) Cardiovasc Res , vol.62 , pp. 202-211
    • Hernanz, R.1    Alonso, M.J.2    Zibrandtsen, H.3    Alvarez, Y.4    Salaices, M.5    Simonsen, U.6
  • 35
    • 0036015050 scopus 로고    scopus 로고
    • Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages
    • Grossman B.J., Shanley T.P., Odoms K., Dunsmore K.E., Denenberg A.G., and Wong H.R. Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages. Inflammation 26 (2002) 129-137
    • (2002) Inflammation , vol.26 , pp. 129-137
    • Grossman, B.J.1    Shanley, T.P.2    Odoms, K.3    Dunsmore, K.E.4    Denenberg, A.G.5    Wong, H.R.6
  • 37
    • 0031020195 scopus 로고    scopus 로고
    • Antioxidant and prooxidant behavior of flavonoids: structureactivity relationships
    • Cao G., Sofic E., and Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structureactivity relationships. Free Radic Biol Med 22 (1997) 749-760
    • (1997) Free Radic Biol Med , vol.22 , pp. 749-760
    • Cao, G.1    Sofic, E.2    Prior, R.L.3
  • 38
    • 0033794615 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin
    • Shieh D.E., Liu L.T., and Lin C.C. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res 20 (2000) 2861-2865
    • (2000) Anticancer Res , vol.20 , pp. 2861-2865
    • Shieh, D.E.1    Liu, L.T.2    Lin, C.C.3
  • 39
    • 0035919828 scopus 로고    scopus 로고
    • Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity
    • Lebeau A., Esclaire F., Rostene W., and Pelaprat D. Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity. Neuroreport 12 (2001) 2199-2202
    • (2001) Neuroreport , vol.12 , pp. 2199-2202
    • Lebeau, A.1    Esclaire, F.2    Rostene, W.3    Pelaprat, D.4
  • 41
    • 0032928083 scopus 로고    scopus 로고
    • Nitric oxide in septic shock
    • Titheradge M.A. Nitric oxide in septic shock. Biochim Biophys Acta 1411 (1999) 437-455
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 437-455
    • Titheradge, M.A.1
  • 42
    • 0030843135 scopus 로고    scopus 로고
    • Nitric oxide and septic shock
    • Thiemermann C. Nitric oxide and septic shock. Gen Pharmacol 29 (1997) 159-166
    • (1997) Gen Pharmacol , vol.29 , pp. 159-166
    • Thiemermann, C.1
  • 43
    • 0030982969 scopus 로고    scopus 로고
    • Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats
    • Takano H., Yoshikawa T., Yamaguchi T., Hongo H., Fujii T., Boku Y., et al. Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats. Eur J Pharmacol 323 (1997) 107-110
    • (1997) Eur J Pharmacol , vol.323 , pp. 107-110
    • Takano, H.1    Yoshikawa, T.2    Yamaguchi, T.3    Hongo, H.4    Fujii, T.5    Boku, Y.6
  • 44
    • 0028806116 scopus 로고
    • Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats
    • Paya D., Maupoil V., Schott C., Rochette L., and Stoclet J.C. Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats. Cardiovasc Res 30 (1995) 952-959
    • (1995) Cardiovasc Res , vol.30 , pp. 952-959
    • Paya, D.1    Maupoil, V.2    Schott, C.3    Rochette, L.4    Stoclet, J.C.5
  • 45
    • 0025811660 scopus 로고
    • Evidence that an l-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin
    • Fleming I., Julou-Schaeffer G., Gray G.A., Parratt J.R., and Stoclet J.C. Evidence that an l-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin. Br J Pharmacol 103 (1991) 1047-1052
    • (1991) Br J Pharmacol , vol.103 , pp. 1047-1052
    • Fleming, I.1    Julou-Schaeffer, G.2    Gray, G.A.3    Parratt, J.R.4    Stoclet, J.C.5
  • 48
    • 17144439794 scopus 로고    scopus 로고
    • Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages
    • Suh N., Honda T., Finlay H.J., Barchowsky A., Williams C., Benoit N.E., et al. Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages. Cancer Res 58 (1998) 717-723
    • (1998) Cancer Res , vol.58 , pp. 717-723
    • Suh, N.1    Honda, T.2    Finlay, H.J.3    Barchowsky, A.4    Williams, C.5    Benoit, N.E.6
  • 49
    • 0027939931 scopus 로고
    • Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase
    • Xie Q.W., Kashiwabara Y., and Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J Biol Chem 269 (1994) 4705-4708
    • (1994) J Biol Chem , vol.269 , pp. 4705-4708
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 50
    • 2942675065 scopus 로고    scopus 로고
    • Nuclear factor-κB activation mediates cellular transformation, proliferation, invasion angiogenesis and metastasis of cancer
    • Shishodia S., and Aggarwal B.B. Nuclear factor-κB activation mediates cellular transformation, proliferation, invasion angiogenesis and metastasis of cancer. Cancer Treat Res 119 (2004) 139-173
    • (2004) Cancer Treat Res , vol.119 , pp. 139-173
    • Shishodia, S.1    Aggarwal, B.B.2
  • 51
    • 0028054728 scopus 로고
    • Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ failure
    • Yoshikawa T., Takano H., Takahashi S., Ichikawa H., and Kondo M. Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ failure. Circ Shock 42 (1994) 53-58
    • (1994) Circ Shock , vol.42 , pp. 53-58
    • Yoshikawa, T.1    Takano, H.2    Takahashi, S.3    Ichikawa, H.4    Kondo, M.5


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