Synergistic effects of baicalein with ciprofloxacin against NorA over-expressed methicillin-resistant Staphylococcus aureus (MRSA) and inhibition of MRSA pyruvate kinase

Journal of Ethnopharmacology

Volumn 137, Issue 1, 2011, Pages 767-773

  Chan, Ben C L ^a   Ip, Margaret ^a   Lau, Clara B S ^a   Lui, S L ^a   Jolivalt, Claude ^b,c   Ganem Elbaz, Carine ^b,c   Litaudon, Marc ^d   Reiner, Neil E ^e   Gong, Huansheng ^e   See, Raymond H ^e   Fung, K P ^a   Leung, P C ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b PSL RESEARCH UNIVERSITY   (France)

^c CNRS   (France)

^d INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Baicalein; Efflux; MDR; MRSA; NorA; Pyruvate kinase; Staphylococcus aureus

Indexed keywords

BACTERIAL ENZYME; BACTERIAL PROTEIN; BAICALEIN; CIPROFLOXACIN; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; KANAMYCIN; NORA PROTEIN; OXACILLIN; PEFLOXACIN; PYRUVATE KINASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DILUTION; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME INHIBITION; GENE OVEREXPRESSION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; TIME;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CIPROFLOXACIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FLAVANONES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PYRUVATE KINASE; TIME FACTORS; UP-REGULATION;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SCUTELLARIA BAICALENSIS; STAPHYLOCOCCUS AUREUS;

EID: 80052024937     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.06.039     Document Type: Article

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