Ameliorative effects of telmisartan on the inflammatory response and impaired spatial memory in a rat model of Alzheimer's disease incorporating additional cerebrovascular disease factors

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 12, 2012, Pages 2141-2147

  Shindo, Taro ^a   Takasaki, Kotaro ^a   Uchida, Kanako ^a   Onimura, Rika ^a   Kubota, Kaori ^a   Uchida, Naoki ^a   Irie, Keiichi ^a   Katsurabayashi, Shutaro ^a   Mishima, Kenichi ^a   Nishimura, Ryoji ^a   Fujiwara, Michihiro ^a   Iwasaki, Katsunori ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Alzheimer disease; Inflammatory; Rat; Telmisartan; Tumor necrosis factor

Indexed keywords

AMYLOID BETA PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TELMISARTAN; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; GENE LOCATION; HIPPOCAMPUS; IMPAIRED SPATIAL MEMORY; INFLAMMATION; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; RAT;

ALZHEIMER DISEASE; AMYLOID; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANILIDES; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZIMIDAZOLES; BENZOATES; BRAIN ISCHEMIA; CEREBROVASCULAR DISORDERS; CEREBRUM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; INFLAMMATION; MALE; MAZE LEARNING; MEMORY; MEMORY DISORDERS; PPAR GAMMA; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84871577272     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00387     Document Type: Article

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